Classification Term: 170763
Acorane sesquiterpenoids (ontology term: 06ea18b9ca314723c9c58463a2414a72)
found 162 associated metabolites at sub_class
metabolite taxonomy ontology rank level.
Ancestor: Sesquiterpenoids
Child Taxonomies: There is no child term of current ontology term.
Thymoquinone
Thymoquinone is a member of the class of 1,4-benzoquinones that is 1,4-bezoquinone in which the hydrogens at positions 2 and 5 are replaced by methyl and isopropyl groups, respectively. It is a natural compound isolated from Nigella sativa which has demonstrated promising chemotherapeutic activity. It has a role as an anti-inflammatory agent, an antioxidant, an adjuvant, an antineoplastic agent, a cardioprotective agent, an antidepressant and a plant metabolite. Thymoquinone is a natural compound with widespread protective effects, including anti-oxidative, anti-inflammatory, immunomodulatory, anti-cancer, and anti-microbial. Thymoquinone is a natural product found in Ayapana triplinervis, Tetraclinis articulata, and other organisms with data available. A member of the class of 1,4-benzoquinones that is 1,4-bezoquinone in which the hydrogens at positions 2 and 5 are replaced by methyl and isopropyl groups, respectively. It is a natural compound isolated from Nigella sativa which has demonstrated promising chemotherapeutic activity. Major constituent of seed oil of black cumin, Nigella sativa (24\\\%). Thymoquinone is found in herbs and spices and winter savory. Thymoquinone is found in herbs and spices. Thymoquinone is a major constituent of seed oil of black cumin, Nigella sativa (24\\\% COVID info from DrugBank Corona-virus Coronavirus SARS-CoV-2 COVID-19 SARS-CoV COVID19 SARS2 SARS Thymoquinone is an orally active natural product isolated from N. sativa Thymoquinone down-regulates the VEGFR2-PI3K-Akt pathway. Thymoquinone has antioxidant, anti-inflammatory, anticancer, antiviral, anticonvulsant, antifungal, antiviral, antiangiogenic activity and hepatoprotective effects. Thymoquinone can be used to study Alzheimer's disease, cancer, cardiovascular disease, infectious disease and inflammation [1][2][3][4][5].
Italicene ether
Italicene ether is found in herbs and spices. Italicene ether is a constituent of Helichrysum italicum (curry plant).
alpha-Alaskene
alpha-Alaskene belongs to the family of Sesquiterpenes. These are terpenes with three consecutive isoprene units
Epiacoronene
4-Acorene-3,8-dione is found in herbs and spices. 4-Acorene-3,8-dione is a constituent of Acorus calamus (sweet flag). Constituent of Acorus calamus (sweet flag). Epiacoronene is found in herbs and spices and root vegetables.
Epiacorone
Constituent of Acorus calamus (sweet flag). Epiacorone is found in herbs and spices and root vegetables. Acorone is found in herbs and spices. Acorone is a constituent of Acorus calamus (sweet flag).
2-Hydroxyacorenone
2-Hydroxyacorenone is found in herbs and spices. 2-Hydroxyacorenone is a constituent of Acorus calamus (sweet flag)
1-Hydroxyepiacorone
1-Hydroxyepiacorone is found in herbs and spices. 1-Hydroxyepiacorone is a constituent of Acorus calamus (sweet flag)
1-Hydroxyacorenone
1-Hydroxyacorenone is found in herbs and spices. 1-Hydroxyacorenone is a constituent of Acorus calamus (sweet flag) Constituent of Acorus calamus (sweet flag). 1-Hydroxyacorenone is found in herbs and spices and root vegetables.
Thymoquinone
Thymoquinone is an orally active natural product isolated from N. sativa Thymoquinone down-regulates the VEGFR2-PI3K-Akt pathway. Thymoquinone has antioxidant, anti-inflammatory, anticancer, antiviral, anticonvulsant, antifungal, antiviral, antiangiogenic activity and hepatoprotective effects. Thymoquinone can be used to study Alzheimer's disease, cancer, cardiovascular disease, infectious disease and inflammation [1][2][3][4][5].
(1R,4S,5R)-1,8-Dimethyl-4-(prop-1-en-2-yl)spiro[4.5]dec-7-ene
(1s,4s,5s)-1-isopropyl-4,8-dimethylspiro[4.5]deca-6,8-diene
(1s,5r)-1,10-dimethyl-8-(prop-1-en-2-yl)spiro[4.5]deca-7,9-dien-6-one
(1s,5s)-1,8-dimethyl-4-(propan-2-ylidene)spiro[4.5]dec-7-ene
1,9-dihydroxy-9-(hydroxymethyl)-1,5,5-trimethylspiro[5.5]undec-3-ene-2,8-dione
(1s,2r,4s,5s)-2-hydroxy-1-isopropyl-4,8-dimethylspiro[4.5]dec-8-en-7-one
2',5,6-trihydroxy-2',4'-dimethyl-4-methylidene-3'a,4',5',7'a-tetrahydrospiro[cyclohexane-1,3'-furo[2,3-c]pyra]-2-en-7'-one
(1r,4s,5s)-1-isopropyl-4,8-dimethylspiro[4.5]dec-8-en-7-one
(4r,5s)-4,8-dimethyl-1-(prop-1-en-2-yl)spiro[4.5]deca-1,7-diene
(1s,3e,5r)-3-[2-(2-hydroxy-6-oxo-4,5-dihydro-3h-pyridin-4-yl)ethylidene]-1,5-dimethyl-4-oxocyclohexyl acetate
(1r,4s,5s,8r)-1-isopropyl-4,8-dimethylspiro[4.5]decane-2,7-dione
(1s,4s,5s,8s)-1-isopropyl-4,8-dimethylspiro[4.5]decane-2,7-dione
9-hydroxy-4-isopropyl-8-methylspiro[4.5]dec-7-ene-1-carboxylic acid
(1r,4r,5r)-1,8-dimethyl-4-(prop-1-en-2-yl)spiro[4.5]dec-7-ene
(4r,5r,6s,7r)-6-(acetyloxy)-4,8-dimethyl-2-oxo-1-(propan-2-ylidene)spiro[4.5]dec-8-en-7-yl acetate
{1-isopropyl-4-methylidenespiro[4.5]dec-7-en-8-yl}methanol
2-[(1r,4r,5r)-4,8-dimethylspiro[4.5]dec-7-en-1-yl]propan-2-ol
n-{7-isopropyl-2,10-dimethylspiro[4.5]dec-1-en-6-yl}methoxycarboximidic acid
2-[(4r)-4,8-dimethylspiro[4.5]dec-7-en-1-yl]propan-2-ol
2',6-dimethyl-3-methylidene-4,7a-dihydro-3ah-spiro[1-benzofuran-7,1'-cyclopentan]-2-one
(6s,9r)-1,9-dihydroxy-9-(hydroxymethyl)-1,5,5-trimethylspiro[5.5]undec-3-ene-2,8-dione
2-bromo-6-isopropyl-4,8a-dimethyl-1,2,3,4,7,8-hexahydronaphthalen-4a-ol
(1r,4r,5r)-1,8-dimethyl-4-(prop-1-en-2-yl)spiro[4.5]dec-7-en-6-one
(1s,2's,3'ar,4's,5s,6s,7'as)-2',5,6-trihydroxy-2',4'-dimethyl-4-methylidene-3'a,4',5',7'a-tetrahydrospiro[cyclohexane-1,3'-furo[2,3-c]pyra]-2-en-7'-one
(1s,4r,5r)-1-(3-hydroxyprop-1-en-2-yl)-4,8-dimethylspiro[4.5]dec-7-en-6-one
2,6,11-trimethyl-8-oxatricyclo[7.4.0.0¹,⁵]tridec-10-en-6-ol
(5r,6s,10s)-7-isopropyl-2,10-dimethylspiro[4.5]dec-1-en-6-ol
(2r,4r,5r)-4-isopropyl-8-methyl-1-methylidenespiro[4.5]dec-7-en-2-ol
(3r,6r)-7-ethyl-3-hydroxy-3,11-dimethyl-5-methylidene-1-oxaspiro[5.5]undecane-2,4-dione
[1-methyl-4-(propan-2-ylidene)spiro[4.5]dec-7-en-8-yl]methanol
(1r,4s,5s,8s)-1-hydroxy-1-isopropyl-4,8-dimethylspiro[4.5]decane-2,7-dione
(1s,4s,5s)-1-hydroxy-1-isopropyl-4,8-dimethylspiro[4.5]dec-8-ene-2,7-dione
6-ethyl-7,9-dimethyl-4,8-dioxospiro[4.5]dec-6-ene-1-carboxylic acid
(1r,4r,5s)-9-hydroxy-1-isopropyl-4,8-dimethylspiro[4.5]dec-8-ene-6,7,10-trione
(2r)-2,6,6,10-tetramethyl-7-oxatricyclo[6.4.0.0¹,⁵]dodec-9-ene
(1s,2r,5r,8r)-2,6,6,10-tetramethyl-7-oxatricyclo[6.4.0.0¹,⁵]dodec-9-ene
n-[(5s,6r,7s,10s)-7-isopropyl-2,10-dimethylspiro[4.5]dec-1-en-6-yl]methanimine
4-isopropyl-8-methyl-1-methylidenespiro[4.5]dec-7-en-2-ol
1,5',6,6-tetramethyl-7-oxaspiro[bicyclo[3.2.1]octane-2,1'-cyclopentane]
n-[(5s,6r,7s,10s)-7-isopropyl-2,10-dimethylspiro[4.5]dec-1-en-6-yl]methoxycarboximidic acid
2-hydroxy-4-isopropyl-1,8-dimethylspiro[4.5]dec-8-en-7-one
(1s,2'r,3'ar,4's,5s,6s,7'as)-5-(acetyloxy)-2'-hydroxy-2',4,4'-trimethyl-7'-oxo-3'a,4',5',7'a-tetrahydrospiro[cyclohexane-1,3'-furo[2,3-c]pyra]-3-en-6-yl acetate
[1-methyl-4-(prop-1-en-2-yl)spiro[4.5]dec-7-en-8-yl]methanol
1-isopropyl-4,8-dimethylspiro[4.5]dec-8-ene-2,7-diol
(4r,5r)-4-isopropyl-8-methyl-1-methylidenespiro[4.5]dec-7-en-2-one
(3s,6r)-7-ethyl-3-hydroxy-3,11-dimethyl-5-methylidene-1-oxaspiro[5.5]undecane-2,4-dione
(1s,5r)-1-isopropyl-8-methyl-4-methylidenespiro[4.5]dec-7-ene
2-{4,8-dimethylspiro[4.5]dec-7-en-1-yl}propane-1,2-diol
[(1s,5r)-1-isopropyl-4-methylidenespiro[4.5]dec-7-en-8-yl]methanol
(1s,2r,4s,5s)-1-isopropyl-4,8-dimethyl-9-oxospiro[4.5]dec-7-en-2-yl acetate
(5s,6r,7s,10r)-7-isopropyl-2,10-dimethylspiro[4.5]dec-1-en-6-ol
(1r,4s,5s)-1,8-dimethyl-4-(prop-1-en-2-yl)spiro[4.5]dec-7-ene
(1s,4s,5s)-1-isopropyl-4,8-dimethylspiro[4.5]dec-8-en-7-ol
8-(hydroxymethyl)-1-isopropyl-4-methylspiro[4.5]dec-8-en-7-one
(1r,5r,6r)-1,8-dimethyl-4-(propan-2-ylidene)spiro[4.5]dec-8-en-6-ol
(1s,2s,4r,5s,9r)-2,9-dihydroxy-4-isopropyl-1,8-dimethylspiro[4.5]dec-7-en-6-one
(1s,4s,5s,9s)-9-hydroxy-4-isopropyl-8-methylspiro[4.5]dec-7-ene-1-carboxylic acid
(1r,5r)-1,8-dimethyl-4-(propan-2-ylidene)spiro[4.5]dec-7-ene
(2s)-2-[(1s,4s,5r,8r)-8-hydroperoxy-4,8-dimethylspiro[4.5]dec-6-en-1-yl]propane-1,2-diol
6-[(3s,3ar,5s,6r,6as)-5-hydroxy-3,6-dimethyl-hexahydrocyclopenta[b]furan-6a-yl]-3-hydroxy-4-methylpyran-2-one
(1r,4s,5s)-1-isopropyl-4,8-dimethylspiro[4.5]dec-8-ene-2,7-dione
1-(3-hydroxyprop-1-en-2-yl)-4,8-dimethylspiro[4.5]dec-7-en-6-one
(1r,2r,4s,5s,9s)-9-hydroxy-8-(hydroxymethyl)-4-methyl-1-(prop-1-en-2-yl)spiro[4.5]dec-7-en-2-yl acetate
(4r,5s)-4,8-dimethyl-1-(propan-2-ylidene)spiro[4.5]dec-7-en-2-one
(1s,2s,4r,5r)-2-hydroxy-4-isopropyl-1,8-dimethylspiro[4.5]dec-8-en-7-one
4,7,7,11-tetramethyl-6-oxatricyclo[6.3.0.0¹,⁵]undecan-5-ol
7-(acetyloxy)-4,8-dimethyl-2-oxo-1-(propan-2-ylidene)spiro[4.5]dec-8-en-6-yl acetate
[(1r,4s,5r)-1-methyl-4-(prop-1-en-2-yl)spiro[4.5]dec-7-en-8-yl]methanol
(1s,4r,5r)-1,8-dimethyl-4-(prop-1-en-2-yl)spiro[4.5]dec-7-ene
(1r)-1,8-dimethyl-4-(prop-1-en-2-yl)spiro[4.5]dec-7-ene
(1r,4r,5s)-9-amino-1-isopropyl-4,8-dimethylspiro[4.5]dec-8-ene-6,7,10-trione
(1s,4s,5s)-1-isopropyl-4-methylspiro[4.5]dec-6-en-8-one
2,9-dihydroxy-4-isopropyl-1,8-dimethylspiro[4.5]dec-7-en-6-one
(1r,2r,4s,5s,9s)-9-hydroxy-4,8-dimethyl-1-(prop-1-en-2-yl)spiro[4.5]dec-7-en-2-yl acetate
(1s,4s,5s)-1-isopropyl-4,8-dimethylspiro[4.5]dec-8-ene-2,7-dione
(1s,4s,5s,8r,11r)-4,7,7,11-tetramethyl-6-oxatricyclo[6.3.0.0¹,⁵]undecan-5-ol
8-chloro-1,5,9-trimethyl-4-methylidenespiro[5.5]undec-8-en-1-ol
C15H23ClO (254.14373379999998)
(1r,4r,5s,10s)-7,10-dihydroxy-1-isopropyl-4,8-dimethylspiro[4.5]dec-7-ene-6,9-dione
n'-{7-isopropyl-2,10-dimethylspiro[4.5]dec-1-en-6-yl}-n,n-dimethylcarbamimidothioic acid
C18H32N2S (308.22860720000006)
9-(bromomethylidene)-1,2,5-trimethylspiro[5.5]undeca-1,7-dien-3-one
C15H19BrO (294.06191839999997)
2-{4,8-dimethylspiro[4.5]dec-7-en-1-yl}propan-2-ol
(1r,3s,5s)-3-[(1r)-1-hydroxy-2-(2-hydroxy-6-oxo-4,5-dihydro-3h-pyridin-4-yl)ethyl]-1,5-dimethyl-4-oxocyclohexyl acetate
n-[(5s,6r,7s,10r)-7-isopropyl-2,10-dimethylspiro[4.5]dec-1-en-6-yl]carboximidic acid
4-isopropyl-8-methyl-1-methylidenespiro[4.5]dec-7-en-2-one
2,10-dihydroxy-4-isopropyl-1,8-dimethylspiro[4.5]dec-8-en-7-one
1,8-dimethyl-4-(propan-2-ylidene)spiro[4.5]dec-8-en-6-ol
(1r,3e,5r)-3-[2-(2-hydroxy-6-oxo-4,5-dihydro-3h-pyridin-4-yl)ethylidene]-1,5-dimethyl-4-oxocyclohexyl acetate
(2's,3ar,7r,7as)-2',6-dimethyl-3-methylidene-4,7a-dihydro-3ah-spiro[1-benzofuran-7,1'-cyclopentan]-2-one
(1s,2r,4s,5s)-1-isopropyl-4,8-dimethylspiro[4.5]dec-8-ene-2,7-diol
9-hydroxy-4,8-dimethyl-1-(prop-1-en-2-yl)spiro[4.5]dec-7-en-2-yl acetate
1-isopropyl-4-methyl-8-methylidenespiro[4.5]dec-9-en-7-ol
7-ethyl-3-hydroxy-3,11-dimethyl-5-methylidene-1-oxaspiro[5.5]undecane-2,4-dione
2-(1,2-dihydroxypropan-2-yl)-6,10-dimethylspiro[4.5]deca-6,9-dien-8-one
1-methyl-4-(prop-1-en-2-yl)spiro[4.5]dec-6-en-8-one
(1s,4s,5r)-1-isopropyl-4-methylspiro[4.5]dec-6-en-8-one
(2s,4r,4ar,8as)-2-bromo-6-isopropyl-4,8a-dimethyl-1,2,3,4,7,8-hexahydronaphthalen-4a-ol
5-(acetyloxy)-2'-hydroxy-2',4,4'-trimethyl-7'-oxo-3'a,4',5',7'a-tetrahydrospiro[cyclohexane-1,3'-furo[2,3-c]pyra]-3-en-6-yl acetate
[(1r,5s)-1-methyl-4-(propan-2-ylidene)spiro[4.5]dec-7-en-8-yl]methanol
(1s,4s,5s)-8-(hydroxymethyl)-1-isopropyl-4-methylspiro[4.5]dec-8-en-7-one
4-(2-hydroxypropan-2-yl)-1,8-dimethylspiro[4.5]dec-7-en-1-ol
8-(hydroxymethyl)-1-isopropyl-4-methylspiro[4.5]dec-8-en-7-ol
(5r,6s,7r,10s)-7-isopropyl-2,10-dimethylspiro[4.5]dec-1-en-6-ol
n-{7-isopropyl-2,10-dimethylspiro[4.5]dec-1-en-6-yl}methanimine
5-isopropyl-1',2-dimethyl-3',8'-dioxaspiro[cyclopentane-1,5'-tricyclo[5.1.0.0²,⁴]octane]
(1s,4s,5s,7r)-8-(hydroxymethyl)-1-isopropyl-4-methylspiro[4.5]dec-8-en-7-ol
n'-[(5s,6r,7s,10r)-7-isopropyl-2,10-dimethylspiro[4.5]dec-1-en-6-yl]-n,n-dimethylcarbamimidothioic acid
C18H32N2S (308.22860720000006)
4,8-dimethyl-1-(propan-2-ylidene)spiro[4.5]dec-7-en-2-one
n-{7-isopropyl-2,10-dimethylspiro[4.5]dec-1-en-6-yl}carboximidic acid
(1s,2s,4r,5s,10r)-2,10-dihydroxy-4-isopropyl-1,8-dimethylspiro[4.5]dec-8-en-7-one
(1s,4s,5s,7r,8r)-8-(hydroxymethyl)-1-isopropyl-4-methylspiro[4.5]dec-9-ene-7,8-diol
(1s,4s,5r)-1,8-dimethyl-4-(prop-1-en-2-yl)spiro[4.5]dec-7-ene
(1s,5r,6s)-8-chloro-1,5,9-trimethyl-4-methylidenespiro[5.5]undec-8-en-1-ol
C15H23ClO (254.14373379999998)
7-isopropyl-4,10-dimethyltricyclo[4.4.0.0¹,⁵]dec-2-ene
9-hydroxy-1-isopropyl-4,8-dimethylspiro[4.5]dec-7-en-6-one
2-{8-hydroperoxy-4,8-dimethylspiro[4.5]dec-6-en-1-yl}propane-1,2-diol
(1r,4r,5s)-1-isopropyl-4,8-dimethylspiro[4.5]dec-8-ene-6,7,10-trione
(1r,4r,5r,7s)-1-isopropyl-4-methyl-8-methylidenespiro[4.5]dec-9-en-7-ol
1,8-dimethyl-4-(propan-2-ylidene)spiro[4.5]dec-7-ene
(1s,4r,5r)-4-(2-hydroxypropan-2-yl)-1,8-dimethylspiro[4.5]dec-7-en-1-ol
(1r,4s,5r)-1-methyl-4-(prop-1-en-2-yl)spiro[4.5]dec-6-en-8-one
2-[(4s,5r)-4,8-dimethylspiro[4.5]dec-7-en-1-yl]propan-2-ol
(1s,2r,4r,5r)-4-(2-hydroxypropan-2-yl)-1,8-dimethylspiro[4.5]dec-7-en-2-ol
2-[(1r,4r,5s)-4,8-dimethylspiro[4.5]dec-7-en-1-yl]propan-2-ol
[(1r,4s,5s)-1-methyl-4-(prop-1-en-2-yl)spiro[4.5]dec-7-en-8-yl]methanol
1,8-dimethyl-4-(prop-1-en-2-yl)spiro[4.5]dec-7-ene
9-hydroxy-8-(hydroxymethyl)-4-methyl-1-(prop-1-en-2-yl)spiro[4.5]dec-7-en-2-yl acetate
(1s,4s,5s)-1-isopropyl-4-methyl-8-methylidenespiro[4.5]dec-6-ene
(2r)-2-[(1r,4r,5s)-4,8-dimethylspiro[4.5]dec-7-en-1-yl]propane-1,2-diol
(1r,5s)-1-isopropyl-4-methylidenespiro[4.5]deca-2,7-diene-8-carboxylic acid
(1s,5r)-1,8-dimethyl-4-(propan-2-ylidene)spiro[4.5]dec-7-ene
(5s,6s,9z)-9-(bromomethylidene)-1,2,5-trimethylspiro[5.5]undeca-1,7-dien-3-one
C15H19BrO (294.06191839999997)
(1s,2r,5r,6r,9r)-2,6,11-trimethyl-8-oxatricyclo[7.4.0.0¹,⁵]tridec-10-en-6-ol
(1r,4s,5s,8s)-1-isopropyl-4,8-dimethylspiro[4.5]decane-2,7-dione
(5s,6s,9e)-9-(bromomethylidene)-1,2,5-trimethylspiro[5.5]undeca-1,7-dien-3-one
C15H19BrO (294.06191839999997)