Classification Term: 169440
Perfluoroalkyl carboxylic acids (ontology term: 2522b14dd9bb8f9747e091d737e3c54d)
found 11 associated metabolites at sub_class metabolite taxonomy ontology rank level.
Ancestor: Alkyl fluorides
Child Taxonomies: There is no child term of current ontology term.
Perfluorohexanoic acid
CONFIDENCE standard compound; INTERNAL_ID 5946 CONFIDENCE standard compound; INTERNAL_ID 2406 INTERNAL_ID 2406; CONFIDENCE standard compound CONFIDENCE Reference Standard (Level 1); INTERNAL_ID 8771 CONFIDENCE standard compound; EAWAG_UCHEM_ID 2715
Perfluoroheptanoic acid
CONFIDENCE standard compound; INTERNAL_ID 5947 CONFIDENCE standard compound; INTERNAL_ID 2410 CONFIDENCE standard compound; EAWAG_UCHEM_ID 2716
Perfluorooctanoic acid
Perfluorooctanoic acid is a fluoroalkanoic acid that is perfluorinated octanoic acid. It has a role as an environmental contaminant, a xenobiotic, a carcinogenic agent, a surfactant and an endocrine disruptor. It is functionally related to a perfluorooctane and an octanoic acid. Perfluorooctanoic Acid (PFOA) can cause cancer according to The National Toxicology Program. It can cause developmental toxicity according to The Environmental Protection Agency (EPA). Perfluorooctanoic acid (PFOA), also known as C8 and perfluorooctanoate, is a synthetic, stable perfluorinated carboxylic acid and fluorosurfactant. One industrial application is as a surfactant in the emulsion polymerization of fluoropolymers. It has been used in the manufacture of such prominent consumer goods as Teflon and Gore-Tex. PFOA has been manufactured since the 1940s in industrial quantities. It is also formed by the degradation of precursors such as some fluorotelomers. PFOA persists indefinitely in the environment. It is a toxicant and carcinogen in animals. PFOA has been detected in the blood of more than 98\% of the general US population in the low and sub-parts per billion range, and levels are higher in chemical plant employees and surrounding subpopulations. Exposure has been associated with increased cholesterol and uric acid levels, and recently higher serum levels of PFOA were found to be associated with increased risk of chronic kidney disease in the general United States population, consistent with earlier animal studies. This association was independent of confounders such as age, sex, race/ethnicity, body mass index, diabetes, hypertension, and serum cholesterol level. .
Perfluoroundecanoic acid
CONFIDENCE standard compound; INTERNAL_ID 5951 CONFIDENCE standard compound; EAWAG_UCHEM_ID 2722
Perfluorobutanoic acid
D019995 - Laboratory Chemicals > D007202 - Indicators and Reagents CONFIDENCE standard compound; INTERNAL_ID 2381 CONFIDENCE Reference Standard (Level 1); INTERNAL_ID 8237