Perfluoroundecanoic acid (BioDeep_00000018372)

   

human metabolite Industrial Pollutants


代谢物信息卡片


Perfluoroundecanoic acid

化学式: C11HF21O2 (563.9641)
中文名称: 二十一氟十一烷酸, 全氟正十一酸, 全氟十一烷酸
谱图信息: 最多检出来源 Homo sapiens(not specific) 49.83%

分子结构信息

SMILES: C(=O)(C(C(C(C(C(C(C(C(C(C(F)(F)F)(F)F)(F)F)(F)F)(F)F)(F)F)(F)F)(F)F)(F)F)(F)F)O
InChI: InChI=1S/C11HF21O2/c12-2(13,1(33)34)3(14,15)4(16,17)5(18,19)6(20,21)7(22,23)8(24,25)9(26,27)10(28,29)11(30,31)32/h(H,33,34)

描述信息

同义名列表

2 个代谢物同义名

Perfluoroundecanoic acid; PFUdA



数据库引用编号

7 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(0)

BioCyc(0)

PlantCyc(0)

代谢反应

0 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

1 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有:

  • PubMed: 来源于PubMed文献库中的文献信息,我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表,这个列表按照代谢物同时出现的文献数量降序排序,取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘,得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序,取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中,存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称,可以跳转到相关代谢物的信息页面。

亚细胞结构定位 关联基因列表


文献列表

  • Yi Liu, Haoyu Zhang, Fei Xu, Xiaozhen Zhang, Nan Zhao, Lei Ding. Associations between serum per- and polyfluoroalkyl substances as mixtures and lipid levels: A cross-sectional study in Jinan. The Science of the total environment. 2024 May; 923(?):171305. doi: 10.1016/j.scitotenv.2024.171305. [PMID: 38423340]
  • Wanying Gui, Hua Guo, Congcong Wang, Minjia Li, Yuanxiang Jin, Kun Zhang, Jiayin Dai, Yanbin Zhao. Comparative developmental toxicities of zebrafish towards structurally diverse per- and polyfluoroalkyl substances. The Science of the total environment. 2023 Aug; 902(?):166569. doi: 10.1016/j.scitotenv.2023.166569. [PMID: 37633367]
  • Emily Marques, Marisa Pfohl, Wei Wei, Giuseppe Tarantola, Lucie Ford, Ogochukwu Amaeze, Jessica Alesio, Sangwoo Ryu, Xuelian Jia, Hao Zhu, Geoffrey D Bothun, Angela Slitt. Replacement per- and polyfluoroalkyl substances (PFAS) are potent modulators of lipogenic and drug metabolizing gene expression signatures in primary human hepatocytes. Toxicology and applied pharmacology. 2022 05; 442(?):115991. doi: 10.1016/j.taap.2022.115991. [PMID: 35337807]
  • Xiu Xin, Haiqiong Chen, Fuhong Tian, Jingjing Li, Haoni Yan, Yige Yu, Feifei Ma, Huitao Li, Yiyan Wang, Xiaoheng Li, Yang Zhu, Ren-Shan Ge. Effects of perfluoroundecanoic acid on the function of Leydig cells in adult male rats. Toxicology and applied pharmacology. 2022 03; 439(?):115903. doi: 10.1016/j.taap.2022.115903. [PMID: 35143807]
  • Xu Han, Lingling Meng, Gaoxin Zhang, Yingming Li, Yali Shi, Qinghua Zhang, Guibin Jiang. Exposure to novel and legacy per- and polyfluoroalkyl substances (PFASs) and associations with type 2 diabetes: A case-control study in East China. Environment international. 2021 11; 156(?):106637. doi: 10.1016/j.envint.2021.106637. [PMID: 33993001]
  • Randi Grønnestad, Silje Modahl Johanson, Mette H B Müller, Daniel Schlenk, Philip Tanabe, Åse Krøkje, Veerle L B Jaspers, Bjørn Munro Jenssen, Erik M Ræder, Jan L Lyche, Qingyang Shi, Augustine Arukwe. Effects of an environmentally relevant PFAS mixture on dopamine and steroid hormone levels in exposed mice. Toxicology and applied pharmacology. 2021 10; 428(?):115670. doi: 10.1016/j.taap.2021.115670. [PMID: 34371090]
  • Haoni Yan, Changchang Li, Cheng Zou, Xiu Xin, Xiaoheng Li, Huitao Li, Yang Li, Zengqiang Li, Yiyan Wang, Haolin Chen, Ren-Shan Ge. Perfluoroundecanoic acid inhibits Leydig cell development in pubertal male rats via inducing oxidative stress and autophagy. Toxicology and applied pharmacology. 2021 03; 415(?):115440. doi: 10.1016/j.taap.2021.115440. [PMID: 33549592]
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  • Yu Ait Bamai, Houman Goudarzi, Atsuko Araki, Emiko Okada, Ikuko Kashino, Chihiro Miyashita, Reiko Kishi. Effect of prenatal exposure to per- and polyfluoroalkyl substances on childhood allergies and common infectious diseases in children up to age 7 years: The Hokkaido study on environment and children's health. Environment international. 2020 10; 143(?):105979. doi: 10.1016/j.envint.2020.105979. [PMID: 32717646]
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  • Youping Tian, Hong Liang, Maohua Miao, Fen Yang, Honglei Ji, Wencheng Cao, Xiaofang Liu, Xiaotian Zhang, Aimin Chen, Hong Xiao, Hui Hu, Wei Yuan. Maternal plasma concentrations of perfluoroalkyl and polyfluoroalkyl substances during pregnancy and anogenital distance in male infants. Human reproduction (Oxford, England). 2019 07; 34(7):1356-1368. doi: 10.1093/humrep/dez058. [PMID: 31242507]
  • Clare E Workman, Allan B Becker, Meghan B Azad, Theo J Moraes, Piush J Mandhane, Stuart E Turvey, Padmaja Subbarao, Jeffrey R Brook, Malcolm R Sears, Charles S Wong. Associations between concentrations of perfluoroalkyl substances in human plasma and maternal, infant, and home characteristics in Winnipeg, Canada. Environmental pollution (Barking, Essex : 1987). 2019 Jun; 249(?):758-766. doi: 10.1016/j.envpol.2019.03.054. [PMID: 30933773]
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  • Miaomiao Wang, Weihong Guo, Steve Gardner, Myrto Petreas, June-Soo Park. Per- and polyfluoroalkyl substances in Northern California cats: Temporal comparison and a possible link to cat hyperthyroidism. Environmental toxicology and chemistry. 2018 10; 37(10):2523-2529. doi: 10.1002/etc.4239. [PMID: 30229994]
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  • Anna Axmon, Jonatan Axelsson, Kristina Jakobsson, Christian H Lindh, Bo A G Jönsson. Time trends between 1987 and 2007 for perfluoroalkyl acids in plasma from Swedish women. Chemosphere. 2014 May; 102(?):61-7. doi: 10.1016/j.chemosphere.2013.12.021. [PMID: 24440039]
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  • Junho Jeon, Kurunthachalam Kannan, Han Kyu Lim, Hyo Bang Moon, Sang D Kim. Bioconcentration of perfluorinated compounds in blackrock fish, Sebastes schlegeli, at different salinity levels. Environmental toxicology and chemistry. 2010 Nov; 29(11):2529-35. doi: 10.1002/etc.310. [PMID: 20853453]
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