Propiolactone (BioDeep_00001867711)
Main id: BioDeep_00000012740
Volatile Flavor Compounds
代谢物信息卡片
β-Propiolactone
化学式: C3H4O2 (72.0211284)
中文名称: 丙内酯, β-丙内酯
谱图信息:
最多检出来源 () 0%
分子结构信息
SMILES: C1COC1=O
InChI: InChI=1S/C3H4O2/c4-3-1-2-5-3/h1-2H2
描述信息
D000890 - Anti-Infective Agents
D004202 - Disinfectants
同义名列表
4 个代谢物同义名
β-Propiolactone; Propiolactone; Propiolactone; beta-Propiolactone
数据库引用编号
11 个数据库交叉引用编号
- ChEBI: CHEBI:49073
- KEGG: C19297
- KEGGdrug: D05630
- PubChem: 2365
- DrugBank: DB09348
- ChEMBL: CHEMBL1200627
- MeSH: Propiolactone
- CAS: 25037-58-5
- CAS: 57-57-8
- PubChem: 124489969
- KNApSAcK: 49073
分类词条
相关代谢途径
Reactome(0)
BioCyc(0)
PlantCyc(0)
代谢反应
0 个相关的代谢反应过程信息。
Reactome(0)
BioCyc(0)
WikiPathways(0)
Plant Reactome(0)
INOH(0)
PlantCyc(0)
COVID-19 Disease Map(0)
PathBank(0)
PharmGKB(0)
0 个相关的物种来源信息
在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：
- PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
- NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
- Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
- Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。
点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。
文献列表
- Dongxiao Liu, Ruth Cruz-Cosme, Yong Wu, Julian Leibowitz, Qiyi Tang. 2-Bromopalmitate depletes lipid droplets to inhibit viral replication.
Journal of virology.
2024 Apr; 98(4):e0017124. doi:
10.1128/jvi.00171-24. [PMID: 38488361] - Dmitry V Bagrov, Grigory S Glukhov, Andrey V Moiseenko, Maria G Karlova, Daniil S Litvinov, Petr А Zaitsev, Liubov I Kozlovskaya, Anna A Shishova, Anastasia A Kovpak, Yury Y Ivin, Anastasia N Piniaeva, Alexey S Oksanich, Viktor P Volok, Dmitry I Osolodkin, Aydar A Ishmukhametov, Alexey M Egorov, Konstantin V Shaitan, Mikhail P Kirpichnikov, Olga S Sokolova. Structural characterization of β-propiolactone inactivated severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) particles.
Microscopy research and technique.
2022 Feb; 85(2):562-569. doi:
10.1002/jemt.23931. [PMID: 34498784] - Radu M Suciu, Irungu K Luvaga, Akram Hazeen, Chulangani Weerasooriya, Stewart K Richardson, Ari J Firestone, Kevin Shannon, Amy R Howell, Benjamin F Cravatt. Chemical proteomic analysis of palmostatin beta-lactone analogs that affect N-Ras palmitoylation.
Bioorganic & medicinal chemistry letters.
2021 12; 53(?):128414. doi:
10.1016/j.bmcl.2021.128414. [PMID: 34666187] - Divya Gupta, Haripriya Parthasarathy, Vishal Sah, Dixit Tandel, Dhiviya Vedagiri, Shashikala Reddy, Krishnan H Harshan. Inactivation of SARS-CoV-2 by β-propiolactone causes aggregation of viral particles and loss of antigenic potential.
Virus research.
2021 11; 305(?):198555. doi:
10.1016/j.virusres.2021.198555. [PMID: 34487766] - Ruta Kulkarni, Harshad P Patil, Sonali Palkar, Sanjay Lalwani, Akhilesh Chandra Mishra, Vidya Arankalle. Anti-SARS-CoV-2 IgG antibody response among Indian COVID-19 patients using β-propiolactone-inactivated, whole virus-based indirect ELISA.
Journal of virological methods.
2021 01; 287(?):113996. doi:
10.1016/j.jviromet.2020.113996. [PMID: 33126149] - Chuang Liu, Luiza Mendonça, Yang Yang, Yuanzhu Gao, Chenguang Shen, Jiwei Liu, Tao Ni, Bin Ju, Congcong Liu, Xian Tang, Jinli Wei, Xiaomin Ma, Yanan Zhu, Weilong Liu, Shuman Xu, Yingxia Liu, Jing Yuan, Jing Wu, Zheng Liu, Zheng Zhang, Lei Liu, Peiyi Wang, Peijun Zhang. The Architecture of Inactivated SARS-CoV-2 with Postfusion Spikes Revealed by Cryo-EM and Cryo-ET.
Structure (London, England : 1993).
2020 11; 28(11):1218-1224.e4. doi:
10.1016/j.str.2020.10.001. [PMID: 33058760] - Shengli Xia, Kai Duan, Yuntao Zhang, Dongyang Zhao, Huajun Zhang, Zhiqiang Xie, Xinguo Li, Cheng Peng, Yanbo Zhang, Wei Zhang, Yunkai Yang, Wei Chen, Xiaoxiao Gao, Wangyang You, Xuewei Wang, Zejun Wang, Zhengli Shi, Yanxia Wang, Xuqin Yang, Lianghao Zhang, Lili Huang, Qian Wang, Jia Lu, Yongli Yang, Jing Guo, Wei Zhou, Xin Wan, Cong Wu, Wenhui Wang, Shihe Huang, Jianhui Du, Ziyan Meng, An Pan, Zhiming Yuan, Shuo Shen, Wanshen Guo, Xiaoming Yang. Effect of an Inactivated Vaccine Against SARS-CoV-2 on Safety and Immunogenicity Outcomes: Interim Analysis of 2 Randomized Clinical Trials.
JAMA.
2020 09; 324(10):951-960. doi:
10.1001/jama.2020.15543. [PMID: 32789505] - Alexander S Jureka, Jesus A Silvas, Christopher F Basler. Propagation, Inactivation, and Safety Testing of SARS-CoV-2.
Viruses.
2020 06; 12(6):. doi:
10.3390/v12060622. [PMID: 32517266] - Yiyi Yan, Xingchen Huo, Taoshan Ai, Jianguo Su. β-glucan and anisodamine can enhance the immersion immune efficacy of inactivated cyprinid herpesvirus 2 vaccine in Carassius auratus gibelio.
Fish & shellfish immunology.
2020 Mar; 98(?):285-295. doi:
10.1016/j.fsi.2020.01.025. [PMID: 31962149] - Tobie D Lee, Olivia W Lee, Kyle R Brimacombe, Lu Chen, Rajarshi Guha, Sabrina Lusvarghi, Bethilehem G Tebase, Carleen Klumpp-Thomas, Robert W Robey, Suresh V Ambudkar, Min Shen, Michael M Gottesman, Matthew D Hall. A High-Throughput Screen of a Library of Therapeutics Identifies Cytotoxic Substrates of P-glycoprotein.
Molecular pharmacology.
2019 11; 96(5):629-640. doi:
10.1124/mol.119.115964. [PMID: 31515284] - Ebtesam Olayan, Manal El-Khadragy, Aly Fahmy Mohamed, Amany Khalil Mohamed, Rania Ibrahim Shebl, Hany M Yehia. Evaluation of Different Stabilizers and Inactivating Compounds for the Enhancement of Vero Cell Rabies Vaccine Stability and Immunogenicity: In Vitro Study.
BioMed research international.
2019; 2019(?):4518163. doi:
10.1155/2019/4518163. [PMID: 31008105] - Tian Qiu, Rahul S Kathayat, Yang Cao, Michael W Beck, Bryan C Dickinson. A Fluorescent Probe with Improved Water Solubility Permits the Analysis of Protein S-Depalmitoylation Activity in Live Cells.
Biochemistry.
2018 01; 57(2):221-225. doi:
10.1021/acs.biochem.7b00835. [PMID: 29023093] - Lijie Tang, Haiyan Kang, Kexin Duan, Mengting Guo, Gaihong Lian, Yang Wu, Yijing Li, Shuai Gao, Yanping Jiang, Jiyuan Yin, Min Liu. Effects of Three Types of Inactivation Agents on the Antibody Response and Immune Protection of Inactivated IHNV Vaccine in Rainbow Trout.
Viral immunology.
2016 09; 29(7):430-5. doi:
10.1089/vim.2016.0035. [PMID: 27548006] - Yutaka Sasaki, Naoto Yoshino, Shigehiro Sato, Yasushi Muraki. Analysis of the beta-propiolactone sensitivity and optimization of inactivation methods for human influenza H3N2 virus.
Journal of virological methods.
2016 09; 235(?):105-111. doi:
10.1016/j.jviromet.2016.04.013. [PMID: 27142111] - Linlin Zhang, Jie Ma, Yuding Fan, Yong Zhou, Jin Xu, Wenzhi Liu, Zemao Gu, Lingbing Zeng. Immune response and protection in gibel carp, Carassius gibelio, after vaccination with β-propiolactone inactivated cyprinid herpesvirus 2.
Fish & shellfish immunology.
2016 Feb; 49(?):344-50. doi:
10.1016/j.fsi.2016.01.003. [PMID: 26772479] - Lixia Jia, Mariangela Chisari, Mohammad H Maktabi, Courtney Sobieski, Hao Zhou, Aaron M Konopko, Brent R Martin, Steven J Mennerick, Kendall J Blumer. A mechanism regulating G protein-coupled receptor signaling that requires cycles of protein palmitoylation and depalmitoylation.
The Journal of biological chemistry.
2014 Feb; 289(9):6249-57. doi:
10.1074/jbc.m113.531475. [PMID: 24385443] - Pierre Bonnafous, Marie-Claire Nicolaï, Jean-Christophe Taveau, Michel Chevalier, Fabienne Barrière, Julie Medina, Olivier Le Bihan, Olivier Adam, Frédéric Ronzon, Olivier Lambert. Treatment of influenza virus with beta-propiolactone alters viral membrane fusion.
Biochimica et biophysica acta.
2014 Jan; 1838(1 Pt B):355-63. doi:
10.1016/j.bbamem.2013.09.021. [PMID: 24140008] - Wen Qi An, Zhi Guo Su, Ruo Wen Pan, Bao Ping Yang, Yong Chao Zhang, Liang Shi, Qing Li. The immunogenicity and protection effect of the BPL-inactivated CA16 vaccine in different animal systems.
Human vaccines & immunotherapeutics.
2014; 10(3):628-39. doi:
10.4161/hv.27295. [PMID: 24401488] - Elaine Santana Rodríguez, Alaín González Pose, María Pilar Rodríguez Moltó, Angela Sosa Espinoza, Pastor Alfonso Zamora, Marisela Suárez Pedroso. Biosafety evaluation of recombinant protein production in goat mammary gland using adenoviral vectors: preliminary study.
Biotechnology journal.
2012 Aug; 7(8):1049-53. doi:
10.1002/biot.201100455. [PMID: 22407796] - Mariarosaria Marinaro, Giovanni Rezza, Giuseppe Del Giudice, Valeriana Colao, Elvira Tarsitano, Michele Camero, Michele Losurdo, Canio Buonavoglia, Maria Tempesta. A caprine herpesvirus 1 vaccine adjuvanted with MF59™ protects against vaginal infection and interferes with the establishment of latency in goats.
PloS one.
2012; 7(4):e34913. doi:
10.1371/journal.pone.0034913. [PMID: 22511971] - Chien-Te Tseng, Elena Sbrana, Naoko Iwata-Yoshikawa, Patrick C Newman, Tania Garron, Robert L Atmar, Clarence J Peters, Robert B Couch. Immunization with SARS coronavirus vaccines leads to pulmonary immunopathology on challenge with the SARS virus.
PloS one.
2012; 7(4):e35421. doi:
10.1371/journal.pone.0035421. [PMID: 22536382] - Hsin-I Chang, Ming-Kung Yeh. Clinical development of liposome-based drugs: formulation, characterization, and therapeutic efficacy.
International journal of nanomedicine.
2012; 7(?):49-60. doi:
10.2147/ijn.s26766. [PMID: 22275822] - Nichole L Hines, Cathy L Miller. Avian paramyxovirus serotype-1: a review of disease distribution, clinical symptoms, and laboratory diagnostics.
Veterinary medicine international.
2012; 2012(?):708216. doi:
10.1155/2012/708216. [PMID: 22577610] - Bernard Desbat, Eloïse Lancelot, Tino Krell, Marie-Claire Nicolaï, Fred Vogel, Michel Chevalier, Frédéric Ronzon. Effect of the β-propiolactone treatment on the adsorption and fusion of influenza A/Brisbane/59/2007 and A/New Caledonia/20/1999 virus H1N1 on a dimyristoylphosphatidylcholine/ganglioside GM3 mixed phospholipids monolayer at the air-water interface.
Langmuir : the ACS journal of surfaces and colloids.
2011 Nov; 27(22):13675-83. doi:
10.1021/la2027175. [PMID: 21981550] - Nicola Decaro, Viviana Mari, Rossana Sciarretta, Valeriana Colao, Michele Losurdo, Cristiana Catella, Gabriella Elia, Vito Martella, Giuseppe Del Giudice, Canio Buonavoglia. Immunogenicity and protective efficacy in dogs of an MF59™-adjuvanted vaccine against recombinant canine/porcine coronavirus.
Vaccine.
2011 Mar; 29(11):2018-23. doi:
10.1016/j.vaccine.2011.01.028. [PMID: 21272607] - Darsaniya Punyadarsaniya, Chi-Hui Liang, Christine Winter, Henning Petersen, Silke Rautenschlein, Isabel Hennig-Pauka, Christel Schwegmann-Wessels, Chung-Yi Wu, Chi-Huey Wong, Georg Herrler. Infection of differentiated porcine airway epithelial cells by influenza virus: differential susceptibility to infection by porcine and avian viruses.
PloS one.
2011; 6(12):e28429. doi:
10.1371/journal.pone.0028429. [PMID: 22174804] - Ming-Jen Cheng, Wen-Li Lo, Lee-Yu Huang, Chyi-Jia Wang, Chung-Yi Chen. Isolation of a 2-oxetanone from the fruits of Synsepalum dulcificum.
Natural product research.
2010 Nov; 24(19):1850-3. doi:
10.1080/14786419.2010.482934. [PMID: 21104531] - Isa S Abubakar, Saidu B Abubakar, Abdulrazaq G Habib, Abdulsalam Nasidi, Nandul Durfa, Peter O Yusuf, Solomon Larnyang, John Garnvwa, Elijah Sokomba, Lateef Salako, R David G Theakston, Ed Juszczak, Nicola Alder, David A Warrell. Randomised controlled double-blind non-inferiority trial of two antivenoms for saw-scaled or carpet viper (Echis ocellatus) envenoming in Nigeria.
PLoS neglected tropical diseases.
2010 Jul; 4(7):e767. doi:
10.1371/journal.pntd.0000767. [PMID: 20668549] - Frank J Dekker, Oliver Rocks, Nachiket Vartak, Sascha Menninger, Christian Hedberg, Rengarajan Balamurugan, Stefan Wetzel, Steffen Renner, Marc Gerauer, Beate Schölermann, Marion Rusch, John W Kramer, Daniel Rauh, Geoffrey W Coates, Luc Brunsveld, Philippe I H Bastiaens, Herbert Waldmann. Small-molecule inhibition of APT1 affects Ras localization and signaling.
Nature chemical biology.
2010 Jun; 6(6):449-56. doi:
10.1038/nchembio.362. [PMID: 20418879] - Jacqueline Gelfi, Michael Pappalardo, Carine Claverys, Brigitte Peralta, Jean-Luc Guerin. Safety and efficacy of an inactivated Carbopol-adjuvanted goose haemorrhagic polyomavirus vaccine for domestic geese.
Avian pathology : journal of the W.V.P.A.
2010 Apr; 39(2):111-6. doi:
10.1080/03079451003604647. [PMID: 20390545] - Noam Erez, Nir Paran, Galia Maik-Rachline, Boaz Politi, Tomer Israely, Paula Schnider, Pinhas Fuchs, Sharon Melamed, Shlomo Lustig. Induction of cell-cell fusion by ectromelia virus is not inhibited by its fusion inhibitory complex.
Virology journal.
2009 Sep; 6(?):151. doi:
10.1186/1743-422x-6-151. [PMID: 19785778] - G Kamaraj, S K Rana, V A Srinivasan. Serological response in cattle immunized with inactivated oil and Algel adjuvant vaccines against infectious bovine rhinotracheitis.
The new microbiologica.
2009 Apr; 32(2):135-41. doi:
NULL. [PMID: 19579689] - Luis Souza de Souza Reis, Neuza Maria Frazatti-Gallina, Rosana de Lima Paoli, Rogerio Giuffrida, Avelino Albas, Eunice Oba, Paulo Eduardo Pardo. Efficiency of Matricaria chamomilla CH12 and number of doses of rabies vaccine on the humoral immune response in cattle.
Journal of veterinary science.
2008 Dec; 9(4):433-5. doi:
10.4142/jvs.2008.9.4.433. [PMID: 19043320] - Bernd Kalbfuss, Yvonne Genzel, Michael Wolff, Anke Zimmermann, Robert Morenweiser, Udo Reichl. Harvesting and concentration of human influenza A virus produced in serum-free mammalian cell culture for the production of vaccines.
Biotechnology and bioengineering.
2007 May; 97(1):73-85. doi:
10.1002/bit.21139. [PMID: 16921531] - Rafael Otero, Guillermo León, José María Gutiérrez, Gustavo Rojas, María Fabiola Toro, Jacqueline Barona, Verónica Rodríguez, Abel Díaz, Vitelbina Núñez, Juan Carlos Quintana, Shirley Ayala, Diana Mosquera, Lesdy L Conrado, Diego Fernández, Yobana Arroyo, Carlos A Paniagua, Mercedes López, Carlos E Ospina, Claudia Alzate, Jorge Fernández, Jazmín J Meza, Juan F Silva, Patricia Ramírez, Patricia E Fabra, Eugenio Ramírez, Elkin Córdoba, Ana B Arrieta, David A Warrell, R David G Theakston. Efficacy and safety of two whole IgG polyvalent antivenoms, refined by caprylic acid fractionation with or without beta-propiolactone, in the treatment of Bothrops asper bites in Colombia.
Transactions of the Royal Society of Tropical Medicine and Hygiene.
2006 Dec; 100(12):1173-82. doi:
10.1016/j.trstmh.2006.01.006. [PMID: 16698053] - Hao Fu Dai, Wen Li Mei. Ophiopojaponin D, a new phenylpropanoid glycoside from Ophiopogon japonicus Ker-Gawl.
Archives of pharmacal research.
2005 Nov; 28(11):1236-8. doi:
10.1007/bf02978205. [PMID: 16350848] - Guillermo León, Bruno Lomonte, José María Gutiérrez. Anticomplementary activity of equine whole IgG antivenoms: comparison of three fractionation protocols.
Toxicon : official journal of the International Society on Toxinology.
2005 Jan; 45(1):123-8. doi:
10.1016/j.toxicon.2004.07.025. [PMID: 15581691] - Yuxian He, Yusen Zhou, Pamela Siddiqui, Shibo Jiang. Inactivated SARS-CoV vaccine elicits high titers of spike protein-specific antibodies that block receptor binding and virus entry.
Biochemical and biophysical research communications.
2004 Dec; 325(2):445-52. doi:
10.1016/j.bbrc.2004.10.052. [PMID: 15530413] - Neuza M Frazatti-Gallina, Regina M Mourão-Fuches, Rosana L Paoli, Maria L N Silva, Cosue Miyaki, Elizabeth J G Valentini, Isaias Raw, Hisako G Higashi. Vero-cell rabies vaccine produced using serum-free medium.
Vaccine.
2004 Dec; 23(4):511-7. doi:
10.1016/j.vaccine.2004.06.014. [PMID: 15530700] - Cun-gui Cheng, Cui-rong Sun, Yuan-jiang Pan. [Direct identification of Ophiogon japonicus (Thunb.)Ker-Gawl. from its confusable varieties by second derivative FTIR spectroscopy combined with statistics].
Guang pu xue yu guang pu fen xi = Guang pu.
2004 Sep; 24(9):1055-9. doi:
". [PMID: 15762521] - Lin Tang, Qingyu Zhu, Ede Qin, Man Yu, Zhifen Ding, Huiying Shi, Xiaojie Cheng, Caiping Wang, Guohui Chang, Qiang Zhu, Fang Fang, Haiyan Chang, Shuangli Li, Xumin Zhang, Xishu Chen, Jun Yu, Jian Wang, Ze Chen. Inactivated SARS-CoV vaccine prepared from whole virus induces a high level of neutralizing antibodies in BALB/c mice.
DNA and cell biology.
2004 Jun; 23(6):391-4. doi:
10.1089/104454904323145272. [PMID: 15231072] - Fawzia M Refaie, Amr Y Esmat, Aly F Mohamed, Walid A Mohamed. The effect of chemical inactivation of bovine viral diarrhea virus with beta-propiolactone and binary ethyleneimine on plasma proteins and coagulation factors.
The Egyptian journal of immunology.
2004; 11(2):9-20. doi:
. [PMID: 16734113] - S J Katona, M Bowen, E R Kaminski. Effect of beta propiolactone viral inactivation on alpha1 antitrypsin values.
Journal of clinical pathology.
2002 Sep; 55(9):659-61. doi:
10.1136/jcp.55.9.659. [PMID: 12194994] - G Giannoukos, D Szapary, C L Smith, J E Meeker, S S Simons. New antiprogestins with partial agonist activity: potential selective progesterone receptor modulators (SPRMs) and probes for receptor- and coregulator-induced changes in progesterone receptor induction properties.
Molecular endocrinology (Baltimore, Md.).
2001 Feb; 15(2):255-70. doi:
10.1210/mend.15.2.0596. [PMID: 11158332] - V Lalosević, L Lazarević-Ivanc, D Lalosević. [Clinical trial of YU BHK Rabivak vaccine against rabies in volunteers].
Medicinski pregled.
2001; 54 Suppl 1(?):23-7. doi:
NULL. [PMID: 12078123] - M S Cortizo, J L Alessandrini, S B Etcheverr, A M Cortizo. A vanadium/aspirin complex controlled release using a poly(beta-propiolactone) film. Effects on osteosarcoma cells.
Journal of biomaterials science. Polymer edition.
2001; 12(9):945-59. doi:
10.1163/156856201753252499. [PMID: 11787522] - S A Lawrence. beta-Propiolactone: viral inactivation in vaccines and plasma products.
PDA journal of pharmaceutical science and technology.
2000 May; 54(3):209-17. doi:
NULL. [PMID: 10927912] - L Perler, H Pfister, M Schweizer, E Peterhans, T W Jungi. A bioassay for interferon type I based on inhibition of Sendai virus growth.
Journal of immunological methods.
1999 Jan; 222(1-2):189-96. doi:
10.1016/s0022-1759(98)00198-7. [PMID: 10022385] - A Scheidler, K Rokos, T Reuter, R Ebermann, G Pauli. Inactivation of viruses by beta-propiolactone in human cryo poor plasma and IgG concentrates.
Biologicals : journal of the International Association of Biological Standardization.
1998 Jun; 26(2):135-44. doi:
10.1006/biol.1998.0125. [PMID: 9811521] - R Guidolin, J F Morais, M A Stephano, J R Marcelino, I K Yamaguchi, H G Higashi. Effect of beta-propiolactone treatment on the complement activation mediated by equine antisera.
Revista do Instituto de Medicina Tropical de Sao Paulo.
1997 Mar; 39(2):119-22. doi:
10.1590/s0036-46651997000200010. [PMID: 9394526] - H Rübsamen-Waigmann. [Virus inactivation of plasma products. Practical methods and their safety].
Deutsche medizinische Wochenschrift (1946).
1994 Mar; 119(10):345-8. doi:
10.1055/s-2008-1058701. [PMID: 8125038] - S G Norley, J Löwer, R Kurth. Insufficient inactivation of HIV-1 in human cryo poor plasma by beta-propiolactone: results from a highly accurate virus detection method.
Biologicals : journal of the International Association of Biological Standardization.
1993 Sep; 21(3):251-8. doi:
10.1006/biol.1993.1082. [PMID: 8117438] - H Dichtelmüller, D Rudnick, B Breuer, K H Gänshirt. Validation of virus inactivation and removal for the manufacturing procedure of two immunoglobulins and a 5\% serum protein solution treated with beta-propiolactone.
Biologicals : journal of the International Association of Biological Standardization.
1993 Sep; 21(3):259-68. doi:
10.1006/biol.1993.1083. [PMID: 8117439] - A E Agbarakwe, S A Misbah, H Griffiths, H M Chapel. Effect of beta propiolactone on specific antibody measurements by ELISA.
Journal of clinical pathology.
1993 Apr; 46(4):368-9. doi:
10.1136/jcp.46.4.368. [PMID: 8496395] - H Suomela. Inactivation of viruses in blood and plasma products.
Transfusion medicine reviews.
1993 Jan; 7(1):42-57. doi:
10.1016/s0887-7963(93)70032-2. [PMID: 8431658] - A L Smith, M S de Souza, D Finzi, S W Barthold. Responses of mice to murine coronavirus immunization.
Archives of virology.
1992; 125(1-4):39-52. doi:
10.1007/bf01309627. [PMID: 1322658] - D J King. Evaluation of different methods of inactivation of Newcastle disease virus and avian influenza virus in egg fluids and serum.
Avian diseases.
1991 Jul; 35(3):505-14. doi:
10.2307/1591214. [PMID: 1835374] - B Horowitz. Inactivation of viruses found with plasma proteins.
Biotechnology (Reading, Mass.).
1991; 19(?):417-30. doi:
10.1016/b978-0-7506-9120-8.50022-6. [PMID: 1786476] - J Sheldon, P Riches, J R Hobbs. Neopterin radioimmunoassay results are unaffected by beta-propiolactone: safer monitoring of HIV-positive serum samples.
Clinical chemistry.
1990 Jan; 36(1):175. doi:
10.1093/clinchem/36.1.175a. [PMID: 2404641] - W Stephan. Inactivation of hepatitis viruses and HIV in plasma and plasma derivatives by treatment with beta-propiolactone/UV irradiation.
Current studies in hematology and blood transfusion.
1989; ?(56):122-7. doi:
10.1159/000416562. [PMID: 2642784] - H Dichtelmüller, W Stephan. [Monitoring of sterilization procedures for plasma derivatives using bacteriophages].
Immunitat und Infektion.
1988 Feb; 16(1):18-20. doi:
NULL. [PMID: 3283031] - M C Anderson, H Baer, D J Frazier, G V Quinnan. The role of specific IgE and beta-propiolactone in reactions resulting from booster doses of human diploid cell rabies vaccine.
The Journal of allergy and clinical immunology.
1987 Dec; 80(6):861-8. doi:
10.1016/s0091-6749(87)80278-6. [PMID: 3693763] - M J Ball. Effect of two disinfectant treatments on laboratory analyses.
Journal of the Royal Society of Medicine.
1987 Aug; 80(8):482-4. doi:
10.1177/014107688708000808. [PMID: 2821254] - M C Swanson, E Rosanoff, M Gurwith, M Deitch, P Schnurrenberger, C E Reed. IgE and IgG antibodies to beta-propiolactone and human serum albumin associated with urticarial reactions to rabies vaccine.
The Journal of infectious diseases.
1987 May; 155(5):909-13. doi:
10.1093/infdis/155.5.909. [PMID: 3559291] - H Dichtelmüller, W Stephan, A M Prince, L Gürtler, F Deinhardt. Inactivation of HIV in plasma derivatives by beta-propiolactone and UV irradiation.
Infection.
1987; 15(5):367-9. doi:
10.1007/bf01647745. [PMID: 3121517] - D Heinrich, U Sugg, H H Brackmann, W Stephan, R Lissner. Virus safety of beta-propiolactone treated plasma preparations. Clinical experiences.
Developments in biological standardization.
1987; 67(?):311-7. doi:
NULL. [PMID: 3649316] - M J Ball, V Spriggs, P M Sutton, H Chapel. Effect of beta-propiolactone--an inhibitor of HTLV III/LAV activity--on immunological analyses.
Journal of immunological methods.
1986 Dec; 95(1):113-6. doi:
10.1016/0022-1759(86)90324-8. [PMID: 3640791] - R H Smith, B Ziola. Cyclophosphamide and dimethyl dioctadecyl ammonium bromide immunopotentiate the delayed-type hypersensitivity response to inactivated enveloped viruses.
Immunology.
1986 Jun; 58(2):245-50. doi:
NULL. [PMID: 2423444] - I S Levenbook, B A Merritt, E A Fitzgerald, B L Elisberg. Sensitization induced in guinea pigs with beta-propiolactone-treated serum albumin: experimental evidence for the cause of allergic reactions in humans receiving human diploid cell rabies vaccines.
International archives of allergy and applied immunology.
1986; 80(1):110-1. doi:
10.1159/000234035. [PMID: 3957443] - M Höckel, R Kaufmann. Placental transfer of class G immunoglobulins treated with beta-propiolactone (beta-PL) for intravenous application--a case report.
Journal of perinatal medicine.
1986; 14(3):205-8. doi:
NULL. [PMID: 3783391] - L E Podoplekina, N A Shutova, Fyodorov YuV. Influence of several chemical reagents on lymphocytic choriomeningitis and Tacaribe viruses.
Virologie.
1986 Jan; 37(1):43-8. doi:
". [PMID: 3962180] - A M Prince, W Stephan, H Dichtelmüller, B Brotman, T Huima. Inactivation of the Hutchinson strain of non-A, non-B hepatitis virus by combined use of beta-propiolactone and ultraviolet irradiation.
Journal of medical virology.
1985 Jun; 16(2):119-25. doi:
10.1002/jmv.1890160204. [PMID: 3925077] - M J Ball, D Griffiths. Effect on chemical analyses of beta-propiolactone treatment of whole blood and plasma.
Lancet (London, England).
1985 May; 1(8438):1160-1. doi:
10.1016/s0140-6736(85)92465-1. [PMID: 2860363] - R L Levings, M L Kaeberle, D E Reed. The effect of some common inactivation procedures on the antigens of bovine herpesvirus 1.
Veterinary microbiology.
1984 Aug; 9(4):313-28. doi:
10.1016/0378-1135(84)90001-4. [PMID: 6093334] - W Stephan. Contributions to the optimal use of human blood. IX. Elimination of hepatitis B transmission by (potentially) infectious plasma derivatives.
Vox sanguinis.
1984; 46(6):421. doi:
NULL. [PMID: 6431692] - A M Prince, W Stephan, B Brotman. Inactivation of non-A, non-B virus infectivity by a beta propiolactone/ultraviolet irradiation treatment and Aerosil adsorption procedure used for preparation of a stabilized human serum.
Vox sanguinis.
1984; 46(2):80-5. doi:
10.1111/j.1423-0410.1984.tb00056.x. [PMID: 6322448] - H Yoshizawa, Y Itoh, S Iwakiri, K Kitajima, Y Noguchi, K Tachibana, T Nakamura, Y Miyakawa, M Mayumi. Beta-propiolactone for the inactivation of non-A/non-B type 1 hepatitis virus capable of inducing cytoplasmic tubular ultrastructures in chimpanzees.
Vox sanguinis.
1984; 46(2):86-91. doi:
10.1111/j.1423-0410.1984.tb00057.x. [PMID: 6422638] - A M Prince, W Stephan, R Kotitschke, B Brotman. Inactivation of hepatitis B and non-A, non-B viruses by combined use of Tween 80, beta-propiolactone, and ultraviolet irradiation.
Thrombosis and haemostasis.
1983 Aug; 50(2):534-6. doi:
10.1055/s-0038-1665248. [PMID: 6415846] - G G Frösner, W Stephan, H Dichtelmüller. Inactivation of hepatitis A virus added to pooled human plasma by beta-propiolactone treatment and ultraviolet irradiation.
European journal of clinical microbiology.
1983 Aug; 2(4):355-7. doi:
10.1007/bf02019469. [PMID: 6313360] - R Kotitschke, W Stephan, A M Prince, B Brotman. Evaluation of thrombogenicity of beta-propiolactone/ultraviolet (beta-PL/UV) treated PPSB in chimpanzees.
Thrombosis research.
1983 May; 30(3):235-44. doi:
10.1016/0049-3848(83)90077-4. [PMID: 6868023] - A M Prince, W Stephan, B Brotman. beta-propiolactone/ultraviolet irradiation: a review of its effectiveness for inactivation of viruses in blood derivatives.
Reviews of infectious diseases.
1983 Jan; 5(1):92-107. doi:
10.1093/clinids/5.1.92. [PMID: 6828813] - D Heinrich, R Kotitschke, H Berthold. Clinical evaluation of the hepatitis safety of a beta-propiolactone/ultraviolet treated factor IX concentrate (PPSB).
Thrombosis research.
1982 Oct; 28(1):75-83. doi:
10.1016/0049-3848(82)90035-4. [PMID: 7157232] - R V Pollock, L E Carmichael. Dog response to inactivated canine parvovirus and feline panleukopenia virus vaccines.
The Cornell veterinarian.
1982 Jan; 72(1):16-35. doi:
. [PMID: 6279359] - W Stephan, H Berthold, A M Prince. Effect of combined treatment of serum containing hepatitis B virus with beta-propiolactone and ultraviolet irradiation.
Vox sanguinis.
1981 Sep; 41(3):134-8. doi:
10.1111/j.1423-0410.1981.tb01026.x. [PMID: 7331286] - W Stephan, R Kotitschke, A M Prince, B Brotman. Long-term tolerance and recovery of beta-propiolactone/ultraviolet (beta PL/UV) treated PPSB in chimpanzees.
Thrombosis and haemostasis.
1981 Aug; 46(2):511-4. doi:
10.1055/s-0038-1653399. [PMID: 7302890] - D C Graves, L V Jones. Early syncytium formation by bovine leukemia virus.
Journal of virology.
1981 Jun; 38(3):1055-63. doi:
10.1128/jvi.38.3.1055-1063.1981. [PMID: 6264150] - R Jennings, T Smith, C W Potter. Use of the enzyme-linked immunosorbent assay (ELISA) for the estimation of serum antibodies in an influenza virus vaccine study.
Medical microbiology and immunology.
1981; 169(4):247-58. doi:
10.1007/bf02125524. [PMID: 6268957] - A M Prince, W Stephan, B Brotman, M C van den Ende. Evaluation of the effect of betapropiolactone/ultraviolet irradiation (BPL/UV) treatment of source plasma on hepatitis transmission by factor IX complex in chimpanzees.
Thrombosis and haemostasis.
1980 Dec; 44(3):138-42. doi:
. [PMID: 7466740] - H H Sonneborn, W Stephan. [Tolerance of beta-propiolactone-treated and UV-irradiated rat serum].
Infusionstherapie und klinische Ernahrung.
1980 Jun; 7(3):145-7. doi:
NULL. [PMID: 7191834] - Y Tomita, T Kuwata. Suppressive effects of interferon on syncytium formation by RD-114 virus in human transformed cells.
The Journal of general virology.
1979 Apr; 43(1):111-7. doi:
10.1099/0022-1317-43-1-111. [PMID: 225412] - Z O Kubinski, H Kubinski. Alterations in Bacillus subtilis transforming DNA induced by beta-propiolactone and 1,3-propane sultone, two mutagenic and carcinogenic alkylating agents.
Journal of bacteriology.
1978 Dec; 136(3):854-66. doi:
10.1128/jb.136.3.854-866.1978. [PMID: 102637] - O Tomori, A Fabiyi. Orungo virus, an orbivirus from Africa: effects of physical and chemical agents.
African journal of medicine and medical sciences.
1977 Mar; 6(1):33-8. doi:
". [PMID: 24332] - T J Wiktor, P C Doherty, H Koprowski. In vitro evidence of cell-mediated immunity after exposure of mice to both live and inactivated rabies virus.
Proceedings of the National Academy of Sciences of the United States of America.
1977 Jan; 74(1):334-8. doi:
10.1073/pnas.74.1.334. [PMID: 299948] - S Barandun, F Skvaril, A Morell. [Prophylaxis and therapy with gamma globulin. General characterization and clinical use of gamma globulin preparations].
Schweizerische medizinische Wochenschrift.
1976 Apr; 106(16):533-42. doi:
NULL. [PMID: 62393] - T A Koski, G G Christianson, F L Cole. Inactivation of mycoplasmas by use of phenol, formalin and beta-propiolactone.
Journal of biological standardization.
1976 Apr; 4(2):151-4. doi:
10.1016/0092-1157(76)90026-3. [PMID: 819443] - B C Del Villano, B P Croker, P J McConahey, F J Dixon. Immunopathogenicity and oncogenicity of murine leukemia viruses. II. Infection of mice and rats with Scripps leukemia virus.
The American journal of pathology.
1976 Feb; 82(2):299-314. doi:
NULL. [PMID: 175661] - D Pruggmayer, W Stephan. Gas chromatographic trace analysis of beta-propiolactone in sterilized serum proteins.
Vox sanguinis.
1976; 31?-73(3):191-8. doi:
10.1159/000467314. [PMID: 969391] - H M Sottnek, W A Cassel, W G Campbell. The pathogenesis of Vaccinia virus toxicity. I. The role of virus-platelet interaction.
Laboratory investigation; a journal of technical methods and pathology.
1975 Nov; 33(5):514-21. doi:
NULL. [PMID: 1195668] - G P Demakov, M A Shilov, V N Ogorodnikova. [Sterilization of the serum of convalescents with betapropiolactone].
Veterinariia.
1975 Aug; ?(8):109-10. doi:
NULL. [PMID: 1216618]