All-trans-retinal (BioDeep_00000875153)

描述信息

A retinal in which all four exocyclic double bonds have E- (trans-) geometry.
13-cis-retinal, also known as vitamin a aldehyde or retinaldehyde, is a member of the class of compounds known as retinoids. Retinoids are oxygenated derivatives of 3,7-dimethyl-1-(2,6,6-trimethylcyclohex-1-enyl)nona-1,3,5,7-tetraene and derivatives thereof. Thus, 13-cis-retinal is considered to be an isoprenoid lipid molecule. 13-cis-retinal is practically insoluble (in water) and an extremely weak basic (essentially neutral) compound (based on its pKa). 13-cis-retinal can be found primarily in blood, as well as throughout most human tissues. Within the cell, 13-cis-retinal is primarily located in the cytoplasm and in the membrane (predicted from logP). It can also be found in the extracellular space. 13-cis-retinal exists in all living organisms, ranging from bacteria to humans. In humans, 13-cis-retinal is involved in the retinol metabolism. 13-cis-retinal is also involved in vitamin A deficiency, which is a metabolic disorder.

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