Azulene (BioDeep_00000409925)

Main id: BioDeep_00000000737

 

PANOMIX_OTCML-2023 natural product


代谢物信息卡片


Azulene

化学式: C10H8 (128.0625968)
中文名称: 甘菊蓝, 偶氮苯
谱图信息: 最多检出来源 () 0%

分子结构信息

SMILES: C12=CC=CC=CC1=CC=C2
InChI: InChI=1S/C10H8/c1-2-5-9-7-4-8-10(9)6-3-1/h1-8H

描述信息

One micro litter of the liquid sample was dropped in a 10 mL glass vial. The vial was placed under the DART ion source.; Direct analysis in real time (DART) is a method of atmospheric pressure chemical ionization (APCI). Protons, H+, generated by glow discharge ionization of the He gas in the ionization chamber, DART-SVP (IonSense Inc., MA, USA), were major reactant ions for the chemical ionization of samples.; The interface introducing the product ions to the mass spectrometer was Vapur Interface (AMR. Inc., Tokyo, Japan). The pressure in the interface was 710 Torr (96.3 kPa).; 1 mg of azulene was placed on glass capillary. The capillary was placed in the gas flow that ran from the ion source.; Azulene was purchased from TCI A0634.; This record was created by the financial support of MEXT/JSPS KAKENHI Grant Number 16HP2005 to the Mass Spectrometry Society of Japan.
D018373 - Peripheral Nervous System Agents > D018689 - Sensory System Agents
D002491 - Central Nervous System Agents > D000700 - Analgesics
D000893 - Anti-Inflammatory Agents
D018501 - Antirheumatic Agents
Azulene (Cyclopentacycloheptene) is as an isomer of naphthalene with high anti-HIV activity. Azulene, isolated from the distillation of chamomile oil, is a scaffold in medicinal chemistry[1][2][3].
Azulene (Cyclopentacycloheptene) is as an isomer of naphthalene with high anti-HIV activity. Azulene, isolated from the distillation of chamomile oil, is a scaffold in medicinal chemistry[1][2][3].

同义名列表

4 个代谢物同义名

Azulene; Cyclopentacycloheptene; Azulene; Azulene



数据库引用编号

11 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(0)

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PlantCyc(0)

代谢反应

0 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

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PharmGKB(0)

48 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：

  • PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。



文献列表

  • Ratan Singh, Dheeraj Rathore. Impact assessment of azulene and chromium on growth and metabolites of wheat and chilli cultivars under biosurfactant augmentation. Ecotoxicology and environmental safety. 2019 Dec; 186(?):109789. doi: 10.1016/j.ecoenv.2019.109789. [PMID: 31629906]
  • Itzamná Baqueiro-Peña, José Á Guerrero-Beltrán. Physicochemical and antioxidant characterization of Justicia spicigera. Food chemistry. 2017 Mar; 218(?):305-312. doi: 10.1016/j.foodchem.2016.09.078. [PMID: 27719914]
  • Petra M Bleeker, Eleni A Spyropoulou, Paul J Diergaarde, Hanne Volpin, Michiel T J De Both, Philipp Zerbe, Joerg Bohlmann, Vasiliki Falara, Yuki Matsuba, Eran Pichersky, Michel A Haring, Robert C Schuurink. RNA-seq discovery, functional characterization, and comparison of sesquiterpene synthases from Solanum lycopersicum and Solanum habrochaites trichomes. Plant molecular biology. 2011 Nov; 77(4-5):323-36. doi: 10.1007/s11103-011-9813-x. [PMID: 21818683]
  • Ompal Singh, Zakia Khanam, Neelam Misra, Manoj Kumar Srivastava. Chamomile (Matricaria chamomilla L.): An overview. Pharmacognosy reviews. 2011 Jan; 5(9):82-95. doi: 10.4103/0973-7847.79103. [PMID: 22096322]
  • Shanmugam Achiraman, Govindaraju Archunan, Ponnirul Ponmanickam, Kamatchi Rameshkumar, Soundrapandian Kannan, George John. 1-Iodo-2 methylundecane [1I2MU]: an estrogen-dependent urinary sex pheromone of female mice. Theriogenology. 2010 Aug; 74(3):345-53. doi: 10.1016/j.theriogenology.2010.01.027. [PMID: 20570325]
  • Soon-Hee Lee, Yong Heo, Young-Chul Kim. Effect of German chamomile oil application on alleviating atopic dermatitis-like immune alterations in mice. Journal of veterinary science. 2010 Mar; 11(1):35-41. doi: 10.4142/jvs.2010.11.1.35. [PMID: 20195063]
  • Angela M Mitchell, Gary A Strobel, Emily Moore, Richard Robison, Joe Sears. Volatile antimicrobials from Muscodor crispans, a novel endophytic fungus. Microbiology (Reading, England). 2010 Jan; 156(Pt 1):270-277. doi: 10.1099/mic.0.032540-0. [PMID: 19797357]
  • Biljana Bozin, Neda Mimica-Dukic, Mirjana Bogavac, Ljiljana Suvajdzic, Natasa Simin, Isidora Samojlik, Maria Couladis. Chemical composition, antioxidant and antibacterial properties of Achillea collina Becker ex Heimerl s.l. and A. pannonica Scheele essential oils. Molecules (Basel, Switzerland). 2008 Sep; 13(9):2058-68. doi: 10.3390/molecules13092058. [PMID: 18830141]
  • Filomena Conforti, Federica Menichini, Monica R Loizzo, A Giancarlo Statti, Antonio Rapisarda, Francesco Menichini, Peter J Houghton. Antioxidant, alpha-amylase inhibitory and brine-shrimp toxicity studies on Centaurea centaurium L. methanolic root extract. Natural product research. 2008; 22(16):1457-66. doi: 10.1080/14786410802098071. [PMID: 19023809]
  • Yoshitaka Iwazu, Sumiko Honma, Genro Fujisawa, Kiyoko Uki, Ichiro Yanaka, Yoshiaki Sato, Mitsunobu Murata, Eiji Kusano, Yasushi Asano. Hyponatremic seizure associated with acute respiratory infection. Clinical and experimental nephrology. 2007 Sep; 11(3):230-234. doi: 10.1007/s10157-007-0476-5. [PMID: 17891351]
  • Gary A Strobel, Katreena Kluck, Wilford M Hess, Joe Sears, David Ezra, Percy N Vargas. Muscodor albus E-6, an endophyte of Guazuma ulmifolia making volatile antibiotics: isolation, characterization and experimental establishment in the host plant. Microbiology (Reading, England). 2007 Aug; 153(Pt 8):2613-2620. doi: 10.1099/mic.0.2007/008912-0. [PMID: 17660425]
  • Hiroyasu Sakai, Miwa Misawa. Effect of sodium azulene sulfonate on capsaicin-induced pharyngitis in rats. Basic & clinical pharmacology & toxicology. 2005 Jan; 96(1):54-9. doi: 10.1111/j.1742-7843.2005.pto960108.x. [PMID: 15667596]
  • Bing Bing Lin, Tadayoshi Morita, Yun-Shan Lin, Hui-Ling Chen. A facile synthesis of 1-ethoxy-4-cyano-5-ethoxycarbonyl-3H-azuleno[1,2-c]pyran-3-one, a selective 15-lipoxygenase inhibitor. Bioorganic & medicinal chemistry letters. 2004 Jan; 14(1):63-5. doi: 10.1016/j.bmcl.2003.10.012. [PMID: 14684299]
  • H Kimata. Enhancement of allergic skin wheal responses in patients with atopic eczema/dermatitis syndrome by playing video games or by a frequently ringing mobile phone. European journal of clinical investigation. 2003 Jun; 33(6):513-7. doi: 10.1046/j.1365-2362.2003.01177.x. [PMID: 12795649]
  • Won Seok Park, Eui Dong Son, Gae Won Nam, Soo Hyun Kim, Min Soo Noh, Byeong Gon Lee, Ih Seop Jang, Se Eun Kim, Jung Joon Lee, Chang Hoon Lee. Torilin from Torilis japonica, as a new inhibitor of testosterone 5 alpha-reductase. Planta medica. 2003 May; 69(5):459-61. doi: 10.1055/s-2003-39717. [PMID: 12802730]
  • Eleni Rekka, Michael Chrysselis, Ioanna Siskou, Angeliki Kourounakis. Synthesis of new azulene derivatives and study of their effect on lipid peroxidation and lipoxygenase activity. Chemical & pharmaceutical bulletin. 2002 Jul; 50(7):904-7. doi: 10.1248/cpb.50.904. [PMID: 12130848]
  • E Mazzio, J Huber, S Darling, N Harris, K F Soliman. Effect of antioxidants on L-glutamate and N-methyl-4-phenylpyridinium ion induced-neurotoxicity in PC12 cells. Neurotoxicology. 2001 Apr; 22(2):283-8. doi: 10.1016/s0161-813x(01)00017-1. [PMID: 11405259]
  • N Chaves, T Sosa, J C Alías, J C Escudero. Identification and effects of interaction phytotoxic compounds from exudate of Cistus ladanifer leaves. Journal of chemical ecology. 2001 Mar; 27(3):611-21. doi: 10.1023/a:1010336921853. [PMID: 11441449]
  • A Espinosa-Mansilla, F Salinas. Kinetic study of the malonaldehyde-azulene reaction determination of malonaldehyde in human plasma. Analytical biochemistry. 1994 Nov; 222(2):396-403. doi: 10.1006/abio.1994.1508. [PMID: 7864364]
  • J L Lamaison, A P Carnat. [Study of azulen in 3 subspecies of Achillea millefolium L]. Annales pharmaceutiques francaises. 1988; 46(2):139-43. doi: ". [PMID: 3214101]
  • R P Hanzlik, P Bhatia. Metabolism of azulene in rats. Xenobiotica; the fate of foreign compounds in biological systems. 1981 Nov; 11(11):779-83. doi: 10.3109/00498258109045882. [PMID: 7336759]
  • R M MUIR, C HANSCH. Azulene derivatives as plant growth regulators. Nature. 1961 May; 190(?):741-2. doi: 10.1038/190741a0. [PMID: 13773632]
  • G KRISTEN, W SCHMIDT. [Chamomile & azulene; pharmacology, therapy & galenicals]. Archiv der Pharmazie und Berichte der Deutschen Pharmazeutischen Gesellschaft. 1957 Aug; 290/62(8-9):105-14. doi: ". [PMID: 13459370]