Tetramethylisoscutellarein (BioDeep_00000227066)
Secondary id: BioDeep_00000230000, BioDeep_00000270086, BioDeep_00000287075
human metabolite PANOMIX_OTCML-2023
代谢物信息卡片
化学式: C19H18O6 (342.1103)
中文名称: 4,5,7,8-四甲氧基黄酮, 4',5,7,8-四甲氧基黄酮, 6-去甲氧基坦格瑞汀
谱图信息:
最多检出来源 Chinese Herbal Medicine(otcml) 90%
分子结构信息
SMILES: c12c(c(c(cc1OC)OC)OC)oc(cc2=O)c1ccc(cc1)OC
InChI: InChI=1S/C19H18O6/c1-21-12-7-5-11(6-8-12)14-9-13(20)17-15(22-2)10-16(23-3)18(24-4)19(17)25-14/h5-10H,1-4H3
描述信息
Tetramethylisoscutellarein, also known as 5784-tetramethoxyflavone, is a member of the class of compounds known as 8-o-methylated flavonoids. 8-o-methylated flavonoids are flavonoids with methoxy groups attached to the C8 atom of the flavonoid backbone. Thus, tetramethylisoscutellarein is considered to be a flavonoid lipid molecule. Tetramethylisoscutellarein is practically insoluble (in water) and an extremely weak acidic compound (based on its pKa). Tetramethylisoscutellarein can be found in sweet orange, which makes tetramethylisoscutellarein a potential biomarker for the consumption of this food product.
6-Demethoxytangeretin is a citrus flavonoid isolated from Citrus reticulata. 6-Demethoxytangeretin exerts anti-inflammatory activity and anti-allergic activity, suppresses production and gene expression of interleukin-6 in human mast cell-1 via anaplastic lymphoma kinase (ALK) and mitogen-activated protein kinase (MAPK) pathways[1]. 6-Demethoxytangeretin facilitates the CRE-mediated transcription associated with learning and memory in cultured hippocampal neurons[2].
6-Demethoxytangeretin is a citrus flavonoid isolated from Citrus reticulata. 6-Demethoxytangeretin exerts anti-inflammatory activity and anti-allergic activity, suppresses production and gene expression of interleukin-6 in human mast cell-1 via anaplastic lymphoma kinase (ALK) and mitogen-activated protein kinase (MAPK) pathways[1]. 6-Demethoxytangeretin facilitates the CRE-mediated transcription associated with learning and memory in cultured hippocampal neurons[2].
同义名列表
11 个代谢物同义名
5,7,8-Trimethoxy-2-(4-methoxyphenyl)-4H-1-benzopyran-4-one; 5,7,8-Trimethoxy-2-(4-methoxyphenyl)-4H-chromen-4-one; Tetra-O-methylisoscutellarein; 5,7,8,4-tetramethoxyflavone; 4,5,7,8-Tetramethoxyflavone; Tetra-O-methylscutellarein; Tetramethylisoscutellarein; 5784-Tetramethoxyflavone; 6-Demethoxytangeritin; 6-Demethoxytangeretin; 6-Demethoxytangeretin
分类词条
相关代谢途径
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代谢反应
0 个相关的代谢反应过程信息。
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INOH(0)
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COVID-19 Disease Map(0)
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3 个相关的物种来源信息
在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有:
- PubMed: 来源于PubMed文献库中的文献信息,我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表,这个列表按照代谢物同时出现的文献数量降序排序,取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
- NCBI Taxonomy: 通过文献数据挖掘,得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序,取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
- Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
- Chemical Reaction: 在化学反应过程中,存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。
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