D-Ribose (BioDeep_00000015049)

 

Secondary id: BioDeep_00000004143, BioDeep_00000406174, BioDeep_00000412695

PANOMIX_OTCML-2023 BioNovoGene_Lab2019


代谢物信息卡片


D-ribo-2,3,4,5-tetrahydroxyvaleraldehyde

化学式: C5H10O5 (150.0528)
中文名称: D-(-)-核糖, D-核糖, (2R,3R,4R)-2,3,4,5-四羟基戊醛
谱图信息: 最多检出来源 Homo sapiens(blood) 17.7%

分子结构信息

SMILES: C(C(C(C(C=O)O)O)O)O
InChI: InChI=1S/C5H10O5/c6-1-2-3(7)4(8)5(9)10-2/h2-9H,1H2/t2-,3-,4-,5?/m1/s1

描述信息

CONFIDENCE standard compound; INTERNAL_ID 227
D-Ribose(mixture of isomers) is an energy enhancer, and acts as a sugar moiety of ATP, and widely used as a metabolic therapy supplement for chronic fatigue syndrome or cardiac energy metabolism. D-Ribose(mixture of isomers) is active in protein glycation, induces NF-κB inflammation in a RAGE-dependent manner[1].
D-Ribose(mixture of isomers) is an energy enhancer, and acts as a sugar moiety of ATP, and widely used as a metabolic therapy supplement for chronic fatigue syndrome or cardiac energy metabolism. D-Ribose(mixture of isomers) is active in protein glycation, induces NF-κB inflammation in a RAGE-dependent manner[1].
D-Ribose(mixture of isomers) is an energy enhancer, and acts as a sugar moiety of ATP, and widely used as a metabolic therapy supplement for chronic fatigue syndrome or cardiac energy metabolism. D-Ribose(mixture of isomers) is active in protein glycation, induces NF-κB inflammation in a RAGE-dependent manner[1].

同义名列表

10 个代谢物同义名

(2R,3R,4R)-2,3,4,5-Tetrahydroxypentanal; D-Ribose; D-ribo-2,3,4,5-tetrahydroxyvaleraldehyde; aldehydo-D-ribo-pentose; aldehydo-D-ribose; ZINC02508189; CHEBI:47014; D-Ribose(mixture of isomers); D-Ribose; (2R,3R,4R)-2,3,4,5-tetrahydroxypentanal



数据库引用编号

36 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(0)

BioCyc(3)

PlantCyc(0)

代谢反应

29 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(29)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

8 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：

  • PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。

亚细胞结构定位 关联基因列表


文献列表

  • Ke Xu, Yi Ren, Shuang Zhao, Jinzhou Feng, Qingyuan Wu, Xue Gong, Jianjun Chen, Peng Xie. Oral D-ribose causes depressive-like behavior by altering glycerophospholipid metabolism via the gut-brain axis. Communications biology. 2024 01; 7(1):69. doi: 10.1038/s42003-023-05759-1. [PMID: 38195757]
  • Jing-Jing Liu, Zhan-Yi Wang, Bin-Bin Jiang, Shu-Qin Gao, Ying-Wu Lin. Protective effect of thymoquinone on glycation of human myoglobin induced by d-ribose. International journal of biological macromolecules. 2023 Dec; 253(Pt 4):127016. doi: 10.1016/j.ijbiomac.2023.127016. [PMID: 37741485]
  • Mahdi Hatami, Maryam Kouchak, Alireza Kheirollah, Layasadat Khorsandi, Mojtaba Rashidi. Quercetin-loaded solid lipid nanoparticles exhibit antitumor activity and suppress the proliferation of triple-negative MDA-MB 231 breast cancer cells: implications for invasive breast cancer treatment. Molecular biology reports. 2023 Oct; ?(?):. doi: 10.1007/s11033-023-08848-w. [PMID: 37831347]
  • Miyeon Kim, Ju Young Bae, Soyeon Yoo, Hyun Woo Kim, Sang Ah Lee, Eui Tae Kim, Gwanpyo Koh. 2-Deoxy-d-ribose induces ferroptosis in renal tubular epithelial cells via ubiquitin-proteasome system-mediated xCT protein degradation. Free radical biology & medicine. 2023 Sep; 208(?):384-393. doi: 10.1016/j.freeradbiomed.2023.08.027. [PMID: 37659699]
  • Amina Arken, Xinmin Zhao, Yanhua Gao, Adil Omar, Dan Tang, Ahmidin Waili, Zi Yang, Yahui Wang, Haji Akbar Aisa, Abulimiti Yili. Biochemical characterization, and anti-inflammatory and antitumor activities of glycoprotein from lamb abomasum. Journal of ethnopharmacology. 2023 Jul; 311(?):116359. doi: 10.1016/j.jep.2023.116359. [PMID: 36965544]
  • Sebastian Marquardt, Pablo Andrés Manavella. A ribose world: current status and future challenges of plant RNA biology. Journal of experimental botany. 2023 04; 74(7):2203-2207. doi: 10.1093/jxb/erad070. [PMID: 37031364]
  • Rafael Itzhakov, Dmitry Tworowski, Noy Sadot, Tali Sayas, Elazar Fallik, Maya Kleiman, Elena Poverenov. Nucleoside-Based Cross-Linkers for Hydrogels with Tunable Properties. ACS applied materials & interfaces. 2023 Feb; 15(5):7359-7370. doi: 10.1021/acsami.2c19525. [PMID: 36701767]
  • Vlasta Matušková, Marek Zatloukal, Tomáš Pospíšil, Jiří Voller, Hana Vylíčilová, Karel Doležal, Miroslav Strnad. From synthesis to the biological effect of isoprenoid 2'-deoxyriboside and 2',3'-dideoxyriboside cytokinin analogues. Phytochemistry. 2023 Jan; 205(?):113481. doi: 10.1016/j.phytochem.2022.113481. [PMID: 36283448]
  • Prairna Balyan, Mohammad Shamsul Ola, Abdullah S Alhomida, Ahmad Ali. D-Ribose-Induced Glycation and Its Attenuation by the Aqueous Extract of Nigella sativa Seeds. Medicina (Kaunas, Lithuania). 2022 Dec; 58(12):. doi: 10.3390/medicina58121816. [PMID: 36557018]
  • Yuxin Cao, Jiayin Wang, Songlin Wu, Xiaochang Yin, Jia Shu, Xing Dai, Yannan Liu, Linhua Sun, Danmeng Zhu, Xing Wang Deng, Keqiong Ye, Weiqiang Qian. The small nucleolar RNA SnoR28 regulates plant growth and development by directing rRNA maturation. The Plant cell. 2022 10; 34(11):4173-4190. doi: 10.1093/plcell/koac265. [PMID: 36005862]
  • Michail Michailidis, Vaia Styliani Titeli, Evangelos Karagiannis, Kyriaki Feidaki, Ioannis Ganopoulos, Georgia Tanou, Anagnostis Argiriou, Athanassios Molassiotis. Tissue-specific transcriptional analysis outlines calcium-induced core metabolic changes in sweet cherry fruit. Plant physiology and biochemistry : PPB. 2022 Oct; 189(?):139-152. doi: 10.1016/j.plaphy.2022.08.022. [PMID: 36087439]
  • Cheng-Pei Chung, Shih-Min Hsia, Wen-Szu Chang, Din-Wen Huang, Wen-Chang Chiang, Mohamed Ali, Ming-Yi Lee, Chi-Hao Wu. Antiglycation Effects of Adlay Seed and Its Active Polyphenol Compounds: An In Vitro Study. Molecules (Basel, Switzerland). 2022 Oct; 27(19):. doi: 10.3390/molecules27196729. [PMID: 36235272]
  • Archana Yadav, Chetna Singh. Cyclooxygenase-2 activates the free radical-mediated apoptosis of polymorphonuclear leukocytes in the maneb- and paraquat-intoxicated rats. Pesticide biochemistry and physiology. 2022 Oct; 187(?):105202. doi: 10.1016/j.pestbp.2022.105202. [PMID: 36127053]
  • Fahaad Alenazi, Mohd Saleem, Azharuddin Sajid Syed Khaja, Mubashir Zafar, Mohammed Salem Alharbi, Turki Al Hagbani, Mohd Yasir Khan, Waseem Ahmad, Saheem Ahmad. Antiglycation potential of plant based TiO2 nanoparticle in D-ribose glycated BSA in vitro. Cell biochemistry and function. 2022 Oct; 40(7):784-796. doi: 10.1002/cbf.3744. [PMID: 36128730]
  • Chuan He, Xiujun Sun, Zhenzhen Huang, Zishan Wang, Xianxian Luo, Jia Song, Xiangjing Wang, Junwei Zhao, Wensheng Xiang. Saccharothrix luteola sp. nov., a novel cellulose-degrading actinobacterium isolated from soil and emended description of the genus Saccharothrix. International journal of systematic and evolutionary microbiology. 2022 Oct; 72(10):. doi: 10.1099/ijsem.0.005572. [PMID: 36268867]
  • Sangsang Tang, Yuanming Shen, Xinyi Wei, Zhangjin Shen, Weiguo Lu, Junfen Xu. Olaparib synergizes with arsenic trioxide by promoting apoptosis and ferroptosis in platinum-resistant ovarian cancer. Cell death & disease. 2022 09; 13(9):826. doi: 10.1038/s41419-022-05257-y. [PMID: 36163324]
  • Xu-Dong Gao, Yue Hu, Wei-Feng Wang, Xiao-Bo Zhao, Xin-Zhen Du, Yan-Ping Shi. Rapid and Selective 19F NMR-Based Sensors for Fingerprint Identification of Ribose. Analytical chemistry. 2022 08; 94(33):11564-11572. doi: 10.1021/acs.analchem.2c01832. [PMID: 35968680]
  • Rikitha S Fernandes, Nilanjan Dey. Synthetic Supramolecular Host for D-(-)-Ribose: Ratiometric Fluorescence Response via Multivalent Lectin-Carbohydrate Interactions. Chembiochem : a European journal of chemical biology. 2022 Jul; 23(13):e202200044. doi: 10.1002/cbic.202200044. [PMID: 35429209]
  • Sharat Sarmah, Archita Goswami, Vinay Kumar Belwal, Atanu Singha Roy. Mitigation of ribose and glyoxal induced glycation, AGEs formation and aggregation of human serum albumin by citrus fruit phytochemicals naringin and naringenin: An insight into their mechanism of action. Food research international (Ottawa, Ont.). 2022 Jul; 157(?):111358. doi: 10.1016/j.foodres.2022.111358. [PMID: 35761621]
  • Yicong Bian, Jian Meng, Sheng Ma, Guangze Li, Yuya Wang, Shaorong Li, Linsheng Liu, Chenrong Huang, Hua Zhang, Dafang Zhong, Liyan Miao. Metabolite profiles and mass balance of fuzuloparib, a novel poly (ADP-ribose) polymerase inhibitor, in subjects with advanced solid cancers. British journal of clinical pharmacology. 2022 07; 88(7):3307-3320. doi: 10.1111/bcp.15256. [PMID: 35112382]
  • Alisha N Jones, André Mourão, Anna Czarna, Alex Matsuda, Roberto Fino, Krzysztof Pyrc, Michael Sattler, Grzegorz M Popowicz. Characterization of SARS-CoV-2 replication complex elongation and proofreading activity. Scientific reports. 2022 Jun; 12(1):9593. doi: 10.1038/s41598-022-13380-1. [PMID: 35688849]
  • Cheng Zheng, Mingjin Qu, Yingmiao Liu, Junzhi Wang, Hanjie Ying. Design and optimizing a new CDP-choline in vitro multienzyme producing process starts from d-ribose. Biotechnology and applied biochemistry. 2022 Jun; 69(3):1029-1035. doi: 10.1002/bab.2173. [PMID: 33885187]
  • Yongquan Xue, Trisha Shamp, G A Nagana Gowda, Michael Crabtree, Debasis Bagchi, Daniel Raftery. A Combination of Nicotinamide and D-Ribose (RiaGev) Is Safe and Effective to Increase NAD+ Metabolome in Healthy Middle-Aged Adults: A Randomized, Triple-Blind, Placebo-Controlled, Cross-Over Pilot Clinical Trial. Nutrients. 2022 May; 14(11):. doi: 10.3390/nu14112219. [PMID: 35684021]
  • Yongfang Li, Dong Zhang, Xin Gao, Xiaowei Wang, Lu Zhang. 2'- and 3'-Ribose Modifications of Nucleotide Analogues Establish the Structural Basis to Inhibit the Viral Replication of SARS-CoV-2. The journal of physical chemistry letters. 2022 May; 13(18):4111-4118. doi: 10.1021/acs.jpclett.2c00087. [PMID: 35503748]
  • Kiran S Toti, John R Jimah, Veronica Salmaso, Jenny E Hinshaw, Kenneth A Jacobson. Synthesis and Effect of Conformationally Locked Carbocyclic Guanine Nucleotides on Dynamin. Biomolecules. 2022 04; 12(4):. doi: 10.3390/biom12040584. [PMID: 35454173]
  • Irmgard U Haussmann, Yanying Wu, Mohanakarthik P Nallasivan, Nathan Archer, Zsuzsanna Bodi, Daniel Hebenstreit, Scott Waddell, Rupert Fray, Matthias Soller. CMTr cap-adjacent 2'-O-ribose mRNA methyltransferases are required for reward learning and mRNA localization to synapses. Nature communications. 2022 03; 13(1):1209. doi: 10.1038/s41467-022-28549-5. [PMID: 35260552]
  • Biebele Abel, Megumi Murakami, Dilip K Tosh, Jinha Yu, Sabrina Lusvarghi, Ryan G Campbell, Zhan-Guo Gao, Kenneth A Jacobson, Suresh V Ambudkar. Interaction of A3 adenosine receptor ligands with the human multidrug transporter ABCG2. European journal of medicinal chemistry. 2022 Mar; 231(?):114103. doi: 10.1016/j.ejmech.2022.114103. [PMID: 35152062]
  • Zhiwei Lu, Xinyue Liu, Xuejiao Li, Chuanjia Zhai, Yulian Shi, Xiaoyan Gao. BH+/MH+-matching method for discovery of cis-diol-containing modified nucleosides in urine by ribose-targeted solid phase extraction followed by dual-mass spectrometry platform identification. Journal of pharmaceutical and biomedical analysis. 2022 Feb; 210(?):114555. doi: 10.1016/j.jpba.2021.114555. [PMID: 34974239]
  • Yuanyuan Jiang, Lanxin Liu, Morenci Manning, Madison Bonahoom, Aaron Lotvola, Zhe Yang, Zeng-Quan Yang. Structural analysis, virtual screening and molecular simulation to identify potential inhibitors targeting 2'-O-ribose methyltransferase of SARS-CoV-2 coronavirus. Journal of biomolecular structure & dynamics. 2022 02; 40(3):1331-1346. doi: 10.1080/07391102.2020.1828172. [PMID: 33016237]
  • Ikuho Ban, Hikari Sugawa, Ryoji Nagai. Protein Modification with Ribose Generates Nδ-(5-hydro-5-methyl-4-imidazolone-2-yl)-ornithine. International journal of molecular sciences. 2022 01; 23(3):. doi: 10.3390/ijms23031224. [PMID: 35163152]
  • Lixian Mou, Pingdong Hu, Xiao Cao, Yue Chen, Yong Xu, Tao He, Yan Wei, Rongqiao He. Comparison of bovine serum albumin glycation by ribose and fructose in vitro and in vivo. Biochimica et biophysica acta. Molecular basis of disease. 2022 01; 1868(1):166283. doi: 10.1016/j.bbadis.2021.166283. [PMID: 34601015]
  • Fangfei Li, Xiaoqiu Wu, Xuekun Fu, Jin Liu, Wangze Song, Gary Guishan Xiao, Aiping Lu, Ge Zhang. Poly (ADP-ribose) polymerase 1 (PARP1) inhibition promotes pulmonary metastasis of osteosarcoma by boosting ezrin phosphorylation. International journal of biological sciences. 2022; 18(3):1238-1253. doi: 10.7150/ijbs.58784. [PMID: 35173550]
  • Fabrice Lucien, Eduardo E Benarroch, Aidan Mullan, Farwa Ali, Bradley F Boeve, Michelle M Mielke, Ronald C Petersen, Yohan Kim, Cole Stang, Emanuele Camerucci, Owen A Ross, Zbigniew K Wszolek, David Knopman, James Bower, Wolfgang Singer, Rodolfo Savica. Poly (ADP-Ribose) and α-synuclein extracellular vesicles in patients with Parkinson disease: A possible biomarker of disease severity. PloS one. 2022; 17(4):e0264446. doi: 10.1371/journal.pone.0264446. [PMID: 35395000]
  • Silvana Casati, Paola Rota, Pietro Allevi, Alessandra Mingione, Roberta Ottria, Pierangela Ciuffreda. Clarifying the Use of Benzylidene Protecting Group for D-(+)-Ribono-1,4-Lactone, an Essential Building Block in the Synthesis of C-Nucleosides. Molecules (Basel, Switzerland). 2021 Oct; 26(21):. doi: 10.3390/molecules26216447. [PMID: 34770855]
  • Afreen Khanam, Sultan Alouffi, Shahnawaz Rehman, Irfan Ahmad Ansari, Uzma Shahab, Saheem Ahmad. An in vitro approach to unveil the structural alterations in d-ribose induced glycated fibrinogen. Journal of biomolecular structure & dynamics. 2021 09; 39(14):5209-5223. doi: 10.1080/07391102.2020.1802339. [PMID: 32772827]
  • Yanhui Lu, Hua Jiang, Huijing Zhang, Ruxue Li, Qi Zhang, Dan Luo, Xue Cai, Mingzi Li. Serum oxidized low density lipoprotein serves as a mediator for the inverse relationship between serum d-ribose and cognitive performance in type 2 diabetic patients. Free radical biology & medicine. 2021 08; 171(?):91-98. doi: 10.1016/j.freeradbiomed.2021.05.015. [PMID: 33989757]
  • Rameez Jabeer Khan, Rajat Kumar Jha, Gizachew Muluneh Amera, Monika Jain, Ekampreet Singh, Amita Pathak, Rashmi Prabha Singh, Jayaraman Muthukumaran, Amit Kumar Singh. Targeting SARS-CoV-2: a systematic drug repurposing approach to identify promising inhibitors against 3C-like proteinase and 2'-O-ribose methyltransferase. Journal of biomolecular structure & dynamics. 2021 05; 39(8):2679-2692. doi: 10.1080/07391102.2020.1753577. [PMID: 32266873]
  • Songlin Wu, Yuqiu Wang, Jiayin Wang, Xilong Li, Jiayang Li, Keqiong Ye. Profiling of RNA ribose methylation in Arabidopsis thaliana. Nucleic acids research. 2021 04; 49(7):4104-4119. doi: 10.1093/nar/gkab196. [PMID: 33784398]
  • Lu Zhang, Dong Zhang, Xiaowei Wang, Congmin Yuan, Yongfang Li, Xilin Jia, Xin Gao, Hui-Ling Yen, Peter Pak-Hang Cheung, Xuhui Huang. 1'-Ribose cyano substitution allows Remdesivir to effectively inhibit nucleotide addition and proofreading during SARS-CoV-2 viral RNA replication. Physical chemistry chemical physics : PCCP. 2021 Mar; 23(10):5852-5863. doi: 10.1039/d0cp05948j. [PMID: 33688867]
  • Chun-Tien Kuo, Robert J Lee, Ramiro Garzon. Methods Used to Make Lipid Nanoparticles to Deliver LNA Gapmers Against lncRNAs into Acute Myeloid Leukemia (AML) Blasts. Methods in molecular biology (Clifton, N.J.). 2021; 2348(?):167-174. doi: 10.1007/978-1-0716-1581-2_11. [PMID: 34160806]
  • Anna Feroz, Peerzada Shariq Shaheen Khaki, Mohd Sajid Khan, Bilqees Bano. Protein aggregation as a consequence of non-enzymatic glycation: Therapeutic intervention using aspartic acid and arginine. International journal of biological macromolecules. 2020 Nov; 163(?):1844-1858. doi: 10.1016/j.ijbiomac.2020.09.083. [PMID: 32956747]
  • Wenni Tian, Nan Xiao, Yunyun Yang, Jie Xiao, Ruiping Zeng, Lanhua Xie, Ziyou Qiu, Pan Li, Bing Du. Structure, antioxidant and immunomodulatory activity of a polysaccharide extracted from Sacha inchi seeds. International journal of biological macromolecules. 2020 Nov; 162(?):116-126. doi: 10.1016/j.ijbiomac.2020.06.150. [PMID: 32565299]
  • Wei Cao, Junqiang Qiu, Tianwei Cai, Longyan Yi, Dan Benardot, Menghui Zou. Effect of D-ribose supplementation on delayed onset muscle soreness induced by plyometric exercise in college students. Journal of the International Society of Sports Nutrition. 2020 Aug; 17(1):42. doi: 10.1186/s12970-020-00371-8. [PMID: 32778175]
  • Rabia Nabi, Sahir Sultan Alvi, Mohammad Shafi Shah, Saheem Ahmad, Mohammad Faisal, Abdulrahman A Alatar, M Salman Khan. A biochemical & biophysical study on in-vitro anti-glycating potential of iridin against d-Ribose modified BSA. Archives of biochemistry and biophysics. 2020 06; 686(?):108373. doi: 10.1016/j.abb.2020.108373. [PMID: 32325089]
  • Huan Zhan, Wei Tang, Heping Cui, Khizar Hayat, Shahzad Hussain, Muhammad Usman Tahir, Songlin Zhang, Xiaoming Zhang, Chi-Tang Ho. Formation kinetics of Maillard reaction intermediates from glycine-ribose system and improving Amadori rearrangement product through controlled thermal reaction and vacuum dehydration. Food chemistry. 2020 May; 311(?):125877. doi: 10.1016/j.foodchem.2019.125877. [PMID: 31780222]
  • Leonor García-Bayona, Laurie E Comstock. Utilizing Ribose Compounds: How Bacteroides PUL It Off. Cell host & microbe. 2020 01; 27(1):6-8. doi: 10.1016/j.chom.2019.12.010. [PMID: 31951823]
  • Veronica Salmaso, Kenneth A Jacobson. Survey of ribose ring pucker of signaling nucleosides and nucleotides. Nucleosides, nucleotides & nucleic acids. 2020; 39(1-3):322-341. doi: 10.1080/15257770.2019.1658115. [PMID: 31460850]
  • Tanjina Kader, Carolyn M Porteous, Gregory T Jones, Nina Dickerhof, Vinod K Narayana, Dedreia Tull, Sreya Taraknath, Sally P A McCormick. Ribose-cysteine protects against the development of atherosclerosis in apoE-deficient mice. PloS one. 2020; 15(2):e0228415. doi: 10.1371/journal.pone.0228415. [PMID: 32084149]
  • Paola Cetera, Maurizio D'Auria, Marisabel Mecca, Luigi Todaro. Gallic acid as main product in the water extractives of Quercus frainetto ten. Natural product research. 2019 Oct; 33(19):2864-2867. doi: 10.1080/14786419.2018.1503266. [PMID: 30427753]
  • Yao Chen, Lexiang Yu, Yujing Wang, Yan Wei, Yong Xu, Tao He, Rongqiao He. d-Ribose contributes to the glycation of serum protein. Biochimica et biophysica acta. Molecular basis of disease. 2019 09; 1865(9):2285-2292. doi: 10.1016/j.bbadis.2019.05.005. [PMID: 31085227]
  • Lexiang Yu, Yao Chen, Yong Xu, Tao He, Yan Wei, Rongqiao He. D-ribose is elevated in T1DM patients and can be involved in the onset of encephalopathy. Aging. 2019 07; 11(14):4943-4969. doi: 10.18632/aging.102089. [PMID: 31307014]
  • Jinni Hong, Owais M Bhat, Guangbi Li, Sara K Dempsey, Qinghua Zhang, Joseph K Ritter, Weiwei Li, Pin-Lan Li. Lysosomal regulation of extracellular vesicle excretion during d-ribose-induced NLRP3 inflammasome activation in podocytes. Biochimica et biophysica acta. Molecular cell research. 2019 05; 1866(5):849-860. doi: 10.1016/j.bbamcr.2019.02.007. [PMID: 30771382]
  • Pyeoung-Ann Kang, Juntaek Oh, Haehee Lee, Claus-Peter Witte, Sangkee Rhee. Crystal structure and mutational analyses of ribokinase from Arabidopsis thaliana. Journal of structural biology. 2019 04; 206(1):110-118. doi: 10.1016/j.jsb.2019.02.007. [PMID: 30822455]
  • Ning Zhang, Shaoyang Zhao, Jinni Hong, Weiwei Li, Xuemei Wang. Protective Effects of Kaempferol on D-Ribose-Induced Mesangial Cell Injury. Oxidative medicine and cellular longevity. 2019; 2019(?):7564207. doi: 10.1155/2019/7564207. [PMID: 31049137]
  • Neeli Habib, Inam Ullah Khan, Xiao Chu, Min Xiao, Shuai Li, Bao-Zhu Fang, Xiao-Yang Zhi, Wen-Jun Li. Actinoplanes deserti sp. nov., isolated from a desert soil sample. Antonie van Leeuwenhoek. 2018 Dec; 111(12):2303-2310. doi: 10.1007/s10482-018-1121-x. [PMID: 29974366]
  • Roberta Balansin Rigon, Sabine Kaessmeyer, Christopher Wolff, Christian Hausmann, Nan Zhang, Michaela Sochorová, Andrej Kováčik, Rainer Haag, Kateřina Vávrová, Martina Ulrich, Monika Schäfer-Korting, Christian Zoschke. Ultrastructural and Molecular Analysis of Ribose-Induced Glycated Reconstructed Human Skin. International journal of molecular sciences. 2018 Nov; 19(11):. doi: 10.3390/ijms19113521. [PMID: 30413126]
  • Jia-Run Han, Jia-Nan Yan, Shi-Guang Sun, Yue Tang, Wen-Hui Shang, Ao-Ting Li, Xiao-Kun Guo, Yi-Nan Du, Hai-Tao Wu, Bei-Wei Zhu, Youling L Xiong. Characteristic antioxidant activity and comprehensive flavor compound profile of scallop (Chlamys farreri) mantle hydrolysates-ribose Maillard reaction products. Food chemistry. 2018 Sep; 261(?):337-347. doi: 10.1016/j.foodchem.2018.04.044. [PMID: 29739602]
  • Alshaymaa Amin Zaki El-Bahy, Yara Mohamed Aboulmagd, Mohanad Zaki. Diabetex: A novel approach for diabetic wound healing. Life sciences. 2018 Aug; 207(?):332-339. doi: 10.1016/j.lfs.2018.06.020. [PMID: 29953880]
  • Jinni Hong, Xuemei Wang, Ning Zhang, Hong Fu, Weiwei Li. D-ribose induces nephropathy through RAGE-dependent NF-κB inflammation. Archives of pharmacal research. 2018 Aug; 41(8):838-847. doi: 10.1007/s12272-018-1061-z. [PMID: 30101366]
  • Dorottya Nagy-Szakal, Dinesh K Barupal, Bohyun Lee, Xiaoyu Che, Brent L Williams, Ellie J R Kahn, Joy E Ukaigwe, Lucinda Bateman, Nancy G Klimas, Anthony L Komaroff, Susan Levine, Jose G Montoya, Daniel L Peterson, Bruce Levin, Mady Hornig, Oliver Fiehn, W Ian Lipkin. Insights into myalgic encephalomyelitis/chronic fatigue syndrome phenotypes through comprehensive metabolomics. Scientific reports. 2018 07; 8(1):10056. doi: 10.1038/s41598-018-28477-9. [PMID: 29968805]
  • Bei Yan, Yao Liu, Aixin Shi, Zhihong Wang, Jiye Aa, Xiaoping Huang, Yi Liu. Investigation of the Antifatigue Effects of Korean Ginseng on Professional Athletes by Gas Chromatography-Time-of-Flight-Mass Spectrometry-Based Metabolomics. Journal of AOAC International. 2018 May; 101(3):701-707. doi: 10.5740/jaoacint.17-0220. [PMID: 28927488]
  • Beibei Wu, Lexiang Yu, Pingdong Hu, Yang Lu, Juan Li, Yan Wei, Rongqiao He. GRP78 protects CHO cells from ribosylation. Biochimica et biophysica acta. Molecular cell research. 2018 Apr; 1865(4):629-637. doi: 10.1016/j.bbamcr.2018.02.001. [PMID: 29410209]
  • Kent R Thurber, Thanh-Ngoc Le, Victor Changcoco, David J R Brook. Verdazyl-ribose: A new radical for solid-state dynamic nuclear polarization at high magnetic field. Journal of magnetic resonance (San Diego, Calif. : 1997). 2018 04; 289(?):122-131. doi: 10.1016/j.jmr.2018.02.016. [PMID: 29501956]
  • Koji Morita, Makoto Koizumi. Synthesis of ENA Nucleotides and ENA Oligonucleotides. Current protocols in nucleic acid chemistry. 2018 03; 72(1):4.79.1-4.79.21. doi: 10.1002/cpnc.46. [PMID: 29927121]
  • Nanhai Zhang, Zongcai Tu, Hui Wang, Guangxian Liu, Zhenxing Wang, Tao Huang, Xu Qin, Xing Xie, A'mei Wang. Liquid Chromatography High-Resolution Mass Spectrometry Identifies the Glycation Sites of Bovine Serum Albumin Induced by d-Ribose with Ultrasonic Treatment. Journal of agricultural and food chemistry. 2018 Jan; 66(3):563-570. doi: 10.1021/acs.jafc.7b04578. [PMID: 29280631]
  • Rebekka Y Schroeder, Anting Zhu, Holger Eubel, Kathleen Dahncke, Claus-Peter Witte. The ribokinases of Arabidopsis thaliana and Saccharomyces cerevisiae are required for ribose recycling from nucleotide catabolism, which in plants is not essential to survive prolonged dark stress. The New phytologist. 2018 Jan; 217(1):233-244. doi: 10.1111/nph.14782. [PMID: 28921561]
  • Nilanjan Dey, Santanu Bhattacharya. Fluorescent Organic Nanoaggregates for Selective Recognition of d-(-)-Ribose in Biological Fluids and Oral Supplements. Chemistry (Weinheim an der Bergstrasse, Germany). 2017 Nov; 23(65):16547-16554. doi: 10.1002/chem.201703034. [PMID: 28875564]
  • Xixi Chen, Tao Su, Yao Chen, Yingge He, Ying Liu, Yong Xu, Yan Wei, Juan Li, Rongqiao He. d-Ribose as a Contributor to Glycated Haemoglobin. EBioMedicine. 2017 Nov; 25(?):143-153. doi: 10.1016/j.ebiom.2017.10.001. [PMID: 29033370]
  • Richard Nitzsche, Özlem Günay-Esiyok, Maximilian Tischer, Vyacheslav Zagoriy, Nishith Gupta. A plant/fungal-type phosphoenolpyruvate carboxykinase located in the parasite mitochondrion ensures glucose-independent survival of Toxoplasma gondii. The Journal of biological chemistry. 2017 09; 292(37):15225-15239. doi: 10.1074/jbc.m117.802702. [PMID: 28726641]
  • Shu-Ying Liu, Chih-Hao Huang, Jia-Ching Shieh, Tai-Lin Lee. Cinnamomum osmophloeum Kanehira ethanol extracts prevents human liver-derived HepG2 cell death from oxidation stress by induction of ghrelin gene expression. Journal of biosciences. 2017 Sep; 42(3):439-448. doi: 10.1007/s12038-017-9697-2. [PMID: 29358557]
  • Ludmilla Bär, Kristin Wächter, Nicole Wege, Alexander Navarrete Santos, Andreas Simm, Michael Föller. Advanced glycation end products stimulate gene expression of fibroblast growth factor 23. Molecular nutrition & food research. 2017 08; 61(8):. doi: 10.1002/mnfr.201601019. [PMID: 28130827]
  • Chen Wang, Yang Liu, Tao-Tao Zhang, Cai-Ge Lu, Ya Liu, Dian-Peng Zhang, Wei-Cheng Liu. Metschnikowia persici sp. nov., A Novel Protease-Producing Yeast Species from China. Current microbiology. 2017 Mar; 74(3):365-370. doi: 10.1007/s00284-017-1194-1. [PMID: 28168603]
  • Firoz Akhter, M Salman Khan, Mohammad Faisal, Abdulrahman A Alatar, Saheem Ahmad. Detection of Circulating Auto-Antibodies Against Ribosylated-LDL in Diabetes Patients. Journal of clinical laboratory analysis. 2017 Mar; 31(2):. doi: 10.1002/jcla.22039. [PMID: 27561427]
  • Kaija-Leena Kolho, Alberto Pessia, Tytti Jaakkola, Willem M de Vos, Vidya Velagapudi. Faecal and Serum Metabolomics in Paediatric Inflammatory Bowel Disease. Journal of Crohn's & colitis. 2017 Mar; 11(3):321-334. doi: 10.1093/ecco-jcc/jjw158. [PMID: 27609529]
  • Azaj Ahmed, Anas Shamsi, Bilqees Bano. Characterizing harmful advanced glycation end-products (AGEs) and ribosylated aggregates of yellow mustard seed phytocystatin: Effects of different monosaccharides. Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy. 2017 Jan; 171(?):183-192. doi: 10.1016/j.saa.2016.08.004. [PMID: 27526342]
  • John W Riggs, Nathan C Rockwell, Philip C Cavales, Judy Callis. Identification of the Plant Ribokinase and Discovery of a Role for Arabidopsis Ribokinase in Nucleoside Metabolism. The Journal of biological chemistry. 2016 Oct; 291(43):22572-22582. doi: 10.1074/jbc.m116.754689. [PMID: 27601466]
  • Lusani Norah Vhangani, Jessy Van Wyk. Antioxidant activity of Maillard reaction products (MRPs) in a lipid-rich model system. Food chemistry. 2016 Oct; 208(?):301-8. doi: 10.1016/j.foodchem.2016.03.100. [PMID: 27132854]
  • Han-Peng Jiang, Jie-Mei Chu, Meng-Dan Lan, Ping Liu, Na Yang, Fang Zheng, Bi-Feng Yuan, Yu-Qi Feng. Comprehensive profiling of ribonucleosides modification by affinity zirconium oxide-silica composite monolithic column online solid-phase microextraction - Mass spectrometry analysis. Journal of chromatography. A. 2016 Sep; 1462(?):90-9. doi: 10.1016/j.chroma.2016.07.086. [PMID: 27495369]
  • Hikari Sugawa, Rei-Ichi Ohno, Jun-Ichi Shirakawa, Akari Nakajima, Amane Kanagawa, Tetsuya Hirata, Tsuyoshi Ikeda, Narumi Moroishi, Mime Nagai, Ryoji Nagai. Eucommia ulmoides extracts prevent the formation of advanced glycation end products. Food & function. 2016 Jun; 7(6):2566-73. doi: 10.1039/c5fo01563d. [PMID: 27080730]
  • Jun Yang, Sunny Sharma, Peter Watzinger, Johannes David Hartmann, Peter Kötter, Karl-Dieter Entian. Mapping of Complete Set of Ribose and Base Modifications of Yeast rRNA by RP-HPLC and Mung Bean Nuclease Assay. PloS one. 2016; 11(12):e0168873. doi: 10.1371/journal.pone.0168873. [PMID: 28033325]
  • Beibei Wu, Yan Wei, Yujing Wang, Tao Su, Lei Zhou, Ying Liu, Rongqiao He. Gavage of D-Ribose induces Aβ-like deposits, Tau hyperphosphorylation as well as memory loss and anxiety-like behavior in mice. Oncotarget. 2015 Oct; 6(33):34128-42. doi: 10.18632/oncotarget.6021. [PMID: 26452037]
  • Vicente Ramírez, Beatriz Gonzalez, Ana López, María José Castelló, María José Gil, Graham J Etherington, Bo Zheng, Peng Chen, Pablo Vera. Loss of a Conserved tRNA Anticodon Modification Perturbs Plant Immunity. PLoS genetics. 2015 Oct; 11(10):e1005586. doi: 10.1371/journal.pgen.1005586. [PMID: 26492405]
  • Nai-dong Chen, Yun-fei Meng, Hou-jun Yao, Cai-yun Cao, Chen Chen, Jun Li. [Study on Monosaccharide Compositions of Polysaccharide in Dendrobium Stems of Different Resources by PMP-HPCE]. Zhong yao cai = Zhongyaocai = Journal of Chinese medicinal materials. 2015 Aug; 38(8):1607-10. doi: ". [PMID: 26983229]
  • Jie-Mei Chu, Chu-Bo Qi, Yun-Qing Huang, Han-Peng Jiang, Yan-Hong Hao, Bi-Feng Yuan, Yu-Qi Feng. Metal Oxide-Based Selective Enrichment Combined with Stable Isotope Labeling-Mass Spectrometry Analysis for Profiling of Ribose Conjugates. Analytical chemistry. 2015 Jul; 87(14):7364-72. doi: 10.1021/acs.analchem.5b01614. [PMID: 26086917]
  • Kevin Trujillo, Silvia Paoletta, Evgeny Kiselev, Kenneth A Jacobson. Molecular modeling of the human P2Y14 receptor: A template for structure-based design of selective agonist ligands. Bioorganic & medicinal chemistry. 2015 Jul; 23(14):4056-64. doi: 10.1016/j.bmc.2015.03.042. [PMID: 25868749]
  • Harold S Bernhardt. The juxtaposition of ribose hydroxyl groups: the root of biological catalysis and the RNA world?. Origins of life and evolution of the biosphere : the journal of the International Society for the Study of the Origin of Life. 2015 Jun; 45(1-2):15-9. doi: 10.1007/s11084-015-9403-z. [PMID: 25716915]
  • Michaela Griesser, Georg Weingart, Katharina Schoedl-Hummel, Nora Neumann, Manuel Becker, Kurt Varmuza, Falk Liebner, Rainer Schuhmacher, Astrid Forneck. Severe drought stress is affecting selected primary metabolites, polyphenols, and volatile metabolites in grapevine leaves (Vitis vinifera cv. Pinot noir). Plant physiology and biochemistry : PPB. 2015 Mar; 88(?):17-26. doi: 10.1016/j.plaphy.2015.01.004. [PMID: 25602440]
  • Jun Yang, Sunny Sharma, Peter Kötter, Karl-Dieter Entian. Identification of a new ribose methylation in the 18S rRNA of S. cerevisiae. Nucleic acids research. 2015 Feb; 43(4):2342-52. doi: 10.1093/nar/gkv058. [PMID: 25653162]
  • I Sadowska-Bartosz, S Galiniak, J Skolimowski, I Stefaniuk, G Bartosz. Nitroxides prevent protein glycoxidation in vitro. Free radical research. 2015 Feb; 49(2):113-21. doi: 10.3109/10715762.2014.982113. [PMID: 25363554]
  • Han-Peng Jiang, Chu-Bo Qi, Jie-Mei Chu, Bi-Feng Yuan, Yu-Qi Feng. Profiling of cis-diol-containing nucleosides and ribosylated metabolites by boronate-affinity organic-silica hybrid monolithic capillary liquid chromatography/mass spectrometry. Scientific reports. 2015 Jan; 5(?):7785. doi: 10.1038/srep07785. [PMID: 25585609]
  • Yanjun Tang, Wei Dong, Keyu Wan, Ligang Zhang, Chun Li, Lili Zhang, Ning Liu. Exopolysaccharide Produced by Lactobacillus Plantarum Induces Maturation of Dendritic Cells in BALB/c Mice. PloS one. 2015; 10(11):e0143743. doi: 10.1371/journal.pone.0143743. [PMID: 26599612]
  • Azad A Siddiqui, Aamir Sohail, Sheraz A Bhat, Md T Rehman, Bilqees Bano. Non-enzymatic Glycation of Almond Cystatin Leads to Conformational Changes and Altered Activity. Protein and peptide letters. 2015; 22(5):449-59. doi: 10.2174/0929866522666150326105704. [PMID: 25808045]
  • Stephen T Sinatra, Corby Caiazzo. (D)-Ribose supplementation in the equine: lack of effect on glycated plasma proteins suggesting safety in humans. Journal of the American College of Nutrition. 2015; 34(2):108-12. doi: 10.1080/07315724.2015.1022459. [PMID: 25789547]
  • Matharage Gayani Dilshara, Kyoung-Tae Lee, Chang-Min Lee, Yung Hyun Choi, Hak-Ju Lee, Il-Whan Choi, Gi-Young Kim. New compound, 5-O-isoferuloyl-2-deoxy-D-ribono-γ-lacton from Clematis mandshurica: Anti-inflammatory effects in lipopolysaccharide-stimulated BV2 microglial cells. International immunopharmacology. 2015 Jan; 24(1):14-23. doi: 10.1016/j.intimp.2014.10.030. [PMID: 25445966]
  • Firoz Akhter, M Salman Khan, Saheem Ahmad. Acquired immunogenicity of calf thymus DNA and LDL modified by D-ribose: a comparative study. International journal of biological macromolecules. 2015 Jan; 72(?):1222-7. doi: 10.1016/j.ijbiomac.2014.10.034. [PMID: 25450543]
  • Tanjina Kader, Carolyn M Porteous, Michael J A Williams, Steven P Gieseg, Sally P A McCormick. Ribose-cysteine increases glutathione-based antioxidant status and reduces LDL in human lipoprotein(a) mice. Atherosclerosis. 2014 Dec; 237(2):725-33. doi: 10.1016/j.atherosclerosis.2014.10.101. [PMID: 25463112]
  • Izabela Sadowska-Bartosz, Sabina Galiniak, Grzegorz Bartosz. Kinetics of glycoxidation of bovine serum albumin by glucose, fructose and ribose and its prevention by food components. Molecules (Basel, Switzerland). 2014 Nov; 19(11):18828-49. doi: 10.3390/molecules191118828. [PMID: 25407721]
  • Weidong Dai, Peiyuan Yin, Zhongda Zeng, Hongwei Kong, Hongwei Tong, Zhiliang Xu, Xin Lu, Rainer Lehmann, Guowang Xu. Nontargeted modification-specific metabolomics study based on liquid chromatography-high-resolution mass spectrometry. Analytical chemistry. 2014 Sep; 86(18):9146-53. doi: 10.1021/ac502045j. [PMID: 25186149]
  • Peter M Clark, Graciela Flores, Nikolai M Evdokimov, Melissa N McCracken, Timothy Chai, Evan Nair-Gill, Fiona O'Mahony, Simon W Beaven, Kym F Faull, Michael E Phelps, Michael E Jung, Owen N Witte. Positron emission tomography probe demonstrates a striking concentration of ribose salvage in the liver. Proceedings of the National Academy of Sciences of the United States of America. 2014 Jul; 111(28):E2866-74. doi: 10.1073/pnas.1410326111. [PMID: 24982199]