ST 29:1;O (BioDeep_00000010969)

Secondary id: BioDeep_00000005557, BioDeep_00000019592, BioDeep_00000840530, BioDeep_00001872301

代谢物信息卡片

4alpha,14alpha-dimethyl-5alpha-cholest-9(11)-en-3beta-ol

化学式: C29H50O (414.386145)
中文名称:
谱图信息: 最多检出来源 Viridiplantae(plant) 0.58%

分子结构信息

SMILES: C12CC[C@@]3([H])C(C)(C)[C@@H](O)CC[C@]3(C)C=1CC[C@]1(C)[C@@]([H])([C@@](C)([H])CCCC(C)C)CC[C@@]21[H]
InChI: InChI=1S/C29H50O/c1-7-21(19(2)3)9-8-20(4)25-12-13-26-24-11-10-22-18-23(30)14-16-28(22,5)27(24)15-17-29(25,26)6/h19-23,25,27,30H,7-18H2,1-6H3/t20-,21+,22+,23+,25-,27+,28+,29-/m1/s1

描述信息

A cholestanoid that is 5alpha-cholesta-8-en-3beta-ol bearing two additional methyl substituents at position 4.

同义名列表

26 个代谢物同义名

4,4-Dimethyl-5alpha-cholesta-8-en-3beta-ol; 4,4-Dimethyl-5alpha-cholest-8-en-3beta-ol; 4,4-Dimethylcholest-8-enol; ST 29:1;O; (24S)-23S,28R-cyclostigmastan-3beta-ol; 23,24-dihydro-5alpha-calystanol; (3beta,5alpha,24R)-Stigmast-8(14)-en-3-ol; 8(14)-Stigmastenol; 5alpha-24Z-ethylidene-cholestan-3beta-ol; 7-dehydrostigmasterol; 28-Isofucostanol; poriferast-8-en-3beta-ol; stigmast-25-en-3beta-ol; poriferast-8(14)-en-3beta-ol; poriferast-7-en-3beta-ol; 23-methylene-24-methyl-5alpha-cholestan-3beta-ol; 23-methylene-24-methylcholestanol; 23,24-Dimethylcholest-22-en-3beta-ol; 14-nor-lanosta-5-en-3beta-ol; 4,24-Dimethylcholest-24-en-3beta-ol; stigmast-22E-en-3beta-ol; 4alpha,14alpha-dimethyl-5alpha-cholest-9(11)-en-3beta-ol; 27-nor-23,26,26-trimethyl-cholest-5-en-3beta-ol; Echissaposterol; 4,4-dimethyl-5alpha-cholest-7-en-3beta-ol; SCHEMBL13770890

数据库引用编号

48 个数据库交叉引用编号

ChEBI: CHEBI:87044
ChEBI: CHEBI:193418
ChEBI: CHEBI:173023
ChEBI: CHEBI:173019
ChEBI: CHEBI:173018
ChEBI: CHEBI:172996
ChEBI: CHEBI:172976
ChEBI: CHEBI:16455
KEGG: C15915
PubChem: 12070223
PubChem: 52931488
PubChem: 16058080
PubChem: 5283664
PubChem: 6321371
PubChem: 5283647
PubChem: 52931361
PubChem: 42608408
PubChem: 42608404
PubChem: 42608403
PubChem: 5283650
PubChem: 52931341
PubChem: 52931326
PubChem: 5460076
LipidMAPS: LMST01010225
LipidMAPS: LMST01110011
LipidMAPS: LMST01040238
LipidMAPS: LMST01040162
LipidMAPS: LMST01040141
LipidMAPS: LMST01040135
LipidMAPS: LMST01040134
LipidMAPS: LMST01040125
LipidMAPS: LMST01031047
LipidMAPS: LMST01030145
LipidMAPS: LMST01030140
LipidMAPS: LMST01030139
LipidMAPS: LMST01030108
LipidMAPS: LMST01010331
LipidMAPS: LMST01010306
LipidMAPS: LMST01010207
CAS: 5241-24-7
CAS: 6384-28-7
PMhub: MS000024881
MetaboLights: MTBLC87044
ChEBI: CHEBI:212200
PubChem: 47205233
NIKKAJI: J2.796.893G
RefMet: 4,4-Dimethyl-5alpha-cholesta-8-en-3beta-ol
RefMet: ST 29:1;O

分类词条

代谢反应

7 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(4)

superpathway of cholesterol biosynthesis: H⁺ + O₂ + a ferrocytochrome b₅ + lathosterol ⟶ 7-dehydrocholesterol + H₂O + a ferricytochrome b₅
cholesterol biosynthesis II (via 24,25-dihydrolanosterol): H⁺ + O₂ + a ferrocytochrome b₅ + lathosterol ⟶ 7-dehydrocholesterol + H₂O + a ferricytochrome b₅
cholesterol biosynthesis II (via 24,25-dihydrolanosterol): 24,25-dihydrolanosterol + O₂ + a reduced [NADPH-hemoprotein reductase] ⟶ 4,4-dimethyl-14α-hydroxymethyl-5α-cholesta-8-en-3β-ol + H₂O + an oxidized [NADPH-hemoprotein reductase]
superpathway of cholesterol biosynthesis: 24,25-dihydrolanosterol + O₂ + a reduced [NADPH-hemoprotein reductase] ⟶ 4,4-dimethyl-14α-hydroxymethyl-5α-cholesta-8-en-3β-ol + H₂O + an oxidized [NADPH-hemoprotein reductase]

WikiPathways(3)

Cholesterol metabolism with Bloch and Kandutsch-Russell pathways: 7-dehydodesmosterol ⟶ 7-dehdrocholesterol
Cholesterol biosynthesis with skeletal dysplasias: 7-Dehydrodesmosterol ⟶ 7-Dehydrocholesterol
Cholesterol biosynthesis pathway in hepatocytes: T-MAS ⟶ Zymosterol

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

8 个相关的物种来源信息

942674 - Amphilectus fucorum: 10.1016/S0040-4020(01)85914-7
85778 - Axinella aruensis: 10.1016/0039-128X(89)90015-9
798305 - Axinella cannabina: 10.1039/P19830000147
54464 - Clerodendrum chinense:
13447 - Conium maculatum: 10.2298/JSC110206128R
68564 - Petrosia ficiformis: 10.1016/0039-128X(80)90095-1
569448 - Salpa thompsoni: 10.1248/CPB.34.4562
4577 - Zea mays: 10.1016/0031-9422(84)83081-2

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：

PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。

文献列表

Yoji Tachibana. [Synthesis and structure-activity relationships of bioactive compounds using sterols]. Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan. 2006 Nov; 126(11):1139-54. doi: 10.1248/yakushi.126.1139. [PMID: 17077615]