Sulfadiazine (BioDeep_00000001571)

 

Secondary id: BioDeep_00001867783

human metabolite blood metabolite Chemicals and Drugs Antibiotics natural product


代谢物信息卡片


4-amino-N-(pyrimidin-2-yl)benzene-1-sulfonamide

化学式: C10H10N4O2S (250.052444)
中文名称: 磺胺嘧啶
谱图信息: 最多检出来源 Mentha canadensis(plant) 1.78%

分子结构信息

SMILES: C1=CN=C(N=C1)NS(=O)(=O)C2=CC=C(C=C2)N
InChI: InChI=1S/C10H10N4O2S/c11-8-2-4-9(5-3-8)17(15,16)14-10-12-6-1-7-13-10/h1-7H,11H2,(H,12,13,14)

描述信息

Sulfadiazine is only found in individuals that have used or taken this drug. It is one of the short-acting sulfonamides used in combination with pyrimethamine to treat toxoplasmosis in patients with acquired immunodeficiency syndrome and in newborns with congenital infections. [PubChem]Sulfadiazine is a competitive inhibitor of the bacterial enzyme dihydropteroate synthetase. This enzyme is needed for the proper processing of para-aminobenzoic acid (PABA) which is essential for folic acid synthesis. The inhibited reaction is necessary in these organisms for the synthesis of folic acid.
J - Antiinfectives for systemic use > J01 - Antibacterials for systemic use > J01E - Sulfonamides and trimethoprim > J01EC - Intermediate-acting sulfonamides
D - Dermatologicals > D06 - Antibiotics and chemotherapeutics for dermatological use > D06B - Chemotherapeutics for topical use > D06BA - Sulfonamides
Antibacterial agent. It is used in some countries for control of bacterial disease in farmed fish. Not approved for aquacultural use in the USA
D000890 - Anti-Infective Agents > D000977 - Antiparasitic Agents > D000981 - Antiprotozoal Agents
C254 - Anti-Infective Agent > C29739 - Sulfonamide Anti-Infective Agent
D000890 - Anti-Infective Agents > D000900 - Anti-Bacterial Agents
D000890 - Anti-Infective Agents > D013424 - Sulfanilamides
CONFIDENCE standard compound; EAWAG_UCHEM_ID 179
CONFIDENCE standard compound; INTERNAL_ID 1011

同义名列表

32 个代谢物同义名

4-amino-N-(pyrimidin-2-yl)benzene-1-sulfonamide; 4-Amino-N-2-pyrimidinylbenzenesulphonamide; 4-Amino-N-2-pyrimidinylbenzenesulfonamide; N(1)-2-Pyrimidinylsulphanilamide; N(1)-2-Pyrimidinylsulfanilamide; N(1)-2-Pyrimidylsulphanilamide; N(1)-2-Pyrimidylsulfanilamide; 2-Sulphanilylaminopyrimidine; 2-Sulfanilylaminopyrimidine; 2-Sulphanilamidopyrimidine; 2-Sulfanilamidopyrimidine; Sulfanilamidopyrimidine; Sulfadiazine, zinc; Zinc sulfadiazine; Sulphapyrimidine; Sulfapyrimidine; Sulphadiazinum; Sulfapyrimidin; Sulfapirimidin; Sulphadiazina; Sulfadiazinum; Sulphadiazine; Sulphadiazin; sulfadiazine; Sulfadiazene; Sulfadiazina; Sulfadiazin; Sulfazine; Sulfazin; SDA; Sulfadiazine; Sulfadiazine



数据库引用编号

38 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(0)

BioCyc(0)

PlantCyc(0)

代谢反应

0 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

9 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：

  • PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。



文献列表

  • Muhammad Nafees, Muhammad Azhar Ali, Linlin Qiu, Ying Yin, Meiling Xu, Guobing Wang, Shafaqat Ali, Hongyan Guo. Mechanistic approach of tannery wastewater and sulfadiazine mutual toxicity in wheat (Triticum aestivum L.) and mitigation through exogenous application of gallic acid. Chemosphere. 2024 Jun; 358(?):142203. doi: 10.1016/j.chemosphere.2024.142203. [PMID: 38697571]
  • Guoqun Yang, Dong Jiang, Li-Jun Huang, Chuantong Cui, Runke Yang, Xin Pi, Xia Peng, Xiaofeng Peng, Jianhui Pi, Ning Li. Distinct toxic effects, gene expression profiles, and phytohormone responses of Polygonatum cyrtonema exposed to two different antibiotics. Journal of hazardous materials. 2024 Mar; 466(?):133639. doi: 10.1016/j.jhazmat.2024.133639. [PMID: 38309169]
  • Zekun Zhang, Le Zhao, Jie Yang, Jiayin Pang, Hans Lambers, Honghua He. Effects of environmentally relevant concentrations of oxytetracycline and sulfadiazine on the bacterial communities, antibiotic resistance genes, and functional genes are different between maize rhizosphere and bulk soil. Environmental science and pollution research international. 2024 Mar; 31(15):22663-22678. doi: 10.1007/s11356-024-32578-6. [PMID: 38409385]
  • Muhammad Nafees, Adiba Khan Sehrish, Sarah Owdah Alomrani, Linlin Qiu, Aasim Saeed, Shoaib Ahmad, Shafaqat Ali, Hongyan Guo. Mechanism and synergistic effect of sulfadiazine (SDZ) and cadmium toxicity in spinach (Spinacia oleracea L.) and its alleviation through zinc fortification. Journal of hazardous materials. 2024 02; 464(?):132903. doi: 10.1016/j.jhazmat.2023.132903. [PMID: 37979422]
  • Ronghui He, Jian Sun, Xiaoyan Bai, Qintie Lin, Yong Yuan, Yaping Zhang, Kang Dai, Zhenbo Xu. A novel alginate-embedded magnetic biochar-anoxygenic photosynthetic bacteria composite microspheres for multipollutant removal: Mechanisms of photo-bioelectrochemical enhancement and excellent reusability performance. Environmental research. 2024 Jan; 247(?):118158. doi: 10.1016/j.envres.2024.118158. [PMID: 38224936]
  • Guangsheng Qian, Jingyi Shao, Peng Hu, Wentao Tang, Yihang Xiao, Tianwei Hao. From micro to macro: The role of seawater in maintaining structural integrity and bioactivity of granules in treating antibiotic-laden mariculture wastewater. Water research. 2023 Nov; 246(?):120702. doi: 10.1016/j.watres.2023.120702. [PMID: 37837903]
  • Samuel Cota Teixeira, Marina Paschoalino, Guilherme de Souza, Alessandra Monteiro Rosini, Joed Pires de Lima Junior, Luana Carvalho Luz, Aryani Felixa Fajardo Martínez, Rosiane Nascimento Alves, Marcos Paulo Oliveira Almeida, Jaqueline Lopes Damasceno, Marcelo José Barbosa Silva, Francesca Ietta, Bellisa Freitas Barbosa, Eloisa Amália Vieira Ferro, Carlos Henrique Gomes Martins. Rottlerin impairs early and late steps of Toxoplasma gondii infection in human trophoblast cells and villous explants. Chemico-biological interactions. 2023 Sep; ?(?):110716. doi: 10.1016/j.cbi.2023.110716. [PMID: 37722575]
  • Hutao Wang, Caiye Hu, Yi Wang, Yangguo Zhao, Chunji Jin, Liang Guo. Elucidating microalgae-mediated metabolism for sulfadiazine removal mechanism and transformation pathways. Environmental pollution (Barking, Essex : 1987). 2023 Jun; 327(?):121598. doi: 10.1016/j.envpol.2023.121598. [PMID: 37031851]
  • Bo Zhao, Jiali Wang, Na Sun, Chunguang Liu. Low concentration of bromide ions improves sulfadiazine phytoremoval and attenuates its phytotoxicity. The Science of the total environment. 2023 Jun; ?(?):164857. doi: 10.1016/j.scitotenv.2023.164857. [PMID: 37321499]
  • Meihong Tan, Wanping Shi, Haifeng Wang, Guanglan Di, Zhengxin Xie, Shisuo Fan, Jun Tang, Fengshou Dong. Effective photodegradation of antibiotics by guest-host synergy between photosensitizer and bismuth vanadate: Underlying mechanism and toxicity assessment. Chemosphere. 2023 Jun; 325(?):138362. doi: 10.1016/j.chemosphere.2023.138362. [PMID: 36905996]
  • Feng Gao, Jin-Long Zhou, Yu-Ru Zhang, Ashiwin Vadiveloo, Qing-Guo Chen, Jun-Zhi Liu, Qiao Yang, Ya-Ming Ge. Efficient coupling of sulfadiazine removal with microalgae lipid production in a membrane photobioreactor. Chemosphere. 2023 Mar; 316(?):137880. doi: 10.1016/j.chemosphere.2023.137880. [PMID: 36649892]
  • Taiwo J Erinle, Martine Boulianne, Deborah Adewole. Red osier dogwood extract vs. trimethoprim-sulfadiazine (Part 2). Pharmacodynamic effects on ileal and cecal microbiota of broiler chickens challenged orally with Salmonella Enteritidis. Poultry science. 2023 Feb; 102(4):102550. doi: 10.1016/j.psj.2023.102550. [PMID: 36854216]
  • Eliška Kobercová, Miroslav Srba, Lukáš Fischer. Sulfadiazine and phosphinothricin selection systems optimised for the transformation of tobacco BY-2 cells. Plant cell reports. 2023 Jan; ?(?):. doi: 10.1007/s00299-022-02975-7. [PMID: 36609768]
  • Kiran Yasmin Khan, Guanlin Li, Daolin Du, Barkat Ali, Shuang Zhang, Meiying Zhong, Peter Joseph Stoffella, Babar Iqbal, Xiaoqiang Cui, Lijiang Fu, Ya Guo. Impact of polystyrene microplastics with combined contamination of norfloxacin and sulfadiazine on Chrysanthemum coronarium L. Environmental pollution (Barking, Essex : 1987). 2023 Jan; 316(Pt 1):120522. doi: 10.1016/j.envpol.2022.120522. [PMID: 36309303]
  • Xinyuan Yao, Jian Sun, Xiaoyan Bai, Yong Yuan, Yaping Zhang, Yanbin Xu, Guofu Huang. A high-efficiency mixotrophic photoelectroactive biofilm reactor (MPBR) for enhanced simultaneous removal of nutrients and antibiotics by integrating light intensity regulation and microbial extracellular electron extraction. Journal of environmental management. 2023 Jan; 325(Pt A):116520. doi: 10.1016/j.jenvman.2022.116520. [PMID: 36306650]
  • Hao Zhang, Zuhan Ge, Yaguang Li, Suzhen Huang, Jibiao Zhang, Zheng Zheng. Response of submerged macrophytes and leaf biofilms to different concentrations of oxytetracycline and sulfadiazine. Chemosphere. 2022 Dec; 308(Pt 1):136098. doi: 10.1016/j.chemosphere.2022.136098. [PMID: 35995188]
  • V Matamoros, M Escolà Casas, E Pastor, Đ Tadić, N Cañameras, N Carazo, J M Bayona. Effects of tetracycline, sulfonamide, fluoroquinolone, and lincosamide load in pig slurry on lettuce: Agricultural and human health implications. Environmental research. 2022 12; 215(Pt 1):114237. doi: 10.1016/j.envres.2022.114237. [PMID: 36084673]
  • Hutao Wang, Caiye Hu, Yi Wang, Chunji Jin, Zonglian She, Liang Guo. Mixotrophic cultivation of Chlorella pyrenoidosa under sulfadiazine stress: High-value product recovery and toxicity tolerance evaluation. Bioresource technology. 2022 Nov; 363(?):127987. doi: 10.1016/j.biortech.2022.127987. [PMID: 36126847]
  • Ronield Fernandez, Nieves R Colás-Ruiz, Gonzalo Martínez-Rodríguez, Pablo A Lara-Martín, Juan Miguel Mancera, Chiara Trombini, Julián Blasco, Miriam Hampel. The antibacterials ciprofloxacin, trimethoprim and sulfadiazine modulate gene expression, biomarkers and metabolites associated with stress and growth in gilthead sea bream (Sparus aurata). Aquatic toxicology (Amsterdam, Netherlands). 2022 Sep; 250(?):106243. doi: 10.1016/j.aquatox.2022.106243. [PMID: 35872527]
  • Shideng Yuan, Heng Zhang, Shiling Yuan. Theoretical insights into the uptake of sulfonamides onto phospholipid bilayers: Mechanisms, interaction and toxicity evaluation. Journal of hazardous materials. 2022 08; 435(?):129033. doi: 10.1016/j.jhazmat.2022.129033. [PMID: 35525012]
  • Xiaoming Wang, Yue Wang, Ci Fang, Qianmei Gong, Jinhu Huang, Yujuan Zhang, Liping Wang. Allicin affects the pharmacokinetics of sulfadiazine and florfenicol by downregulating the expression of jejunum P-gp and BCRP in broilers. Poultry science. 2022 Jul; 101(7):101947. doi: 10.1016/j.psj.2022.101947. [PMID: 35688033]
  • Yue Wang, Jinghua Li, Yao Lei, Xiaoqiang Li, Dillirani Nagarajan, Duu-Jong Lee, Jo-Shu Chang. Bioremediation of sulfonamides by a microalgae-bacteria consortium - Analysis of pollutants removal efficiency, cellular composition, and bacterial community. Bioresource technology. 2022 May; 351(?):126964. doi: 10.1016/j.biortech.2022.126964. [PMID: 35272036]
  • Carl Ekstrand, Katarina Nostell, Ronette Gehring, Ulf Bondesson, Johan Bröjer. The disposition of trimethoprim and sulfadiazine in neonatal foals after intravenous administration. Veterinary medicine and science. 2022 05; 8(3):1065-1071. doi: 10.1002/vms3.763. [PMID: 35152563]
  • Barrios Leda Castaño, Andrea Alice Silva, Lina L Hernandez-Velasco, Ana Paula Da Silva Pinheiro, Daniel Gibaldi, José Roberto Mineo, Neide Maria Silva, Joseli Lannes-Vieira. Sulfadiazine Plus Pyrimethamine Therapy Reversed Multiple Behavioral and Neurocognitive Changes in Long-Term Chronic Toxoplasmosis by Reducing Brain Cyst Load and Inflammation-Related Alterations. Frontiers in immunology. 2022; 13(?):822567. doi: 10.3389/fimmu.2022.822567. [PMID: 35572567]
  • Ning Xu, Yu Fu, Xiaomei Zhang, Yongtao Liu, Yibin Yang, Shun Zhou, Jing Dong, Qiuhong Yang, Xiaohui Ai. The pharmacokinetic characteristics of sulfadiazine in channel catfish (Ictalurus punctatus) following oral and intravenous administrations. Journal of veterinary pharmacology and therapeutics. 2022 Jan; 45(1):16-22. doi: 10.1111/jvp.13032. [PMID: 34779521]
  • Ming-Liang Zhang, Wei-Xia Li, Xiao-Yan Wang, Ya-Li Wu, Xiao-Fei Chen, Hui Zhang, Liu-Qing Yang, Cheng-Zhao Wu, Shu-Qi Zhang, Yu-Long Chen, Ke-Ran Feng, Bin Wang, Lu Niu, De-Xin Kong, Jin-Fa Tang. Oxymatrine ameliorates experimental autoimmune encephalomyelitis by rebalancing the homeostasis of gut microbiota and reducing blood-brain barrier disruption. Frontiers in cellular and infection microbiology. 2022; 12(?):1095053. doi: 10.3389/fcimb.2022.1095053. [PMID: 36710971]
  • Fahimeh Nematollahi, Tahoora Shomali, Bahman Abdi-Hachesoo, Azizollah Khodakaram-Tafti. Effect of prophylactic vitamin C administration on the efficiency of florfenicol or sulfadiazine-trimethoprim antimicrobial therapy in chickens with staphylococcal arthritis. Tropical animal health and production. 2021 Dec; 54(1):25. doi: 10.1007/s11250-021-03033-2. [PMID: 34957533]
  • Linlin Qiu, Tim J Daniell, Steven A Banwart, Muhammad Nafees, Jingjing Wu, Wenchao Du, Ying Yin, Hongyan Guo. Insights into the mechanism of the interference of sulfadiazine on soil microbial community and function. Journal of hazardous materials. 2021 10; 419(?):126388. doi: 10.1016/j.jhazmat.2021.126388. [PMID: 34171664]
  • Aline Reetz Conceição, Deisi Nara Belucik, Lilian Missio, Luiz Gustavo Brenner, Matheus Henrique Monteiro, Kleber Silva Ribeiro, Deise Fialho Costa, Maria Clara da Silva Valadão, Alessandra Gonçalves Commodaro, João Rafael de Oliveira Dias, Rubens Belfort. Ocular Findings in Infants with Congenital Toxoplasmosis after a Toxoplasmosis Outbreak. Ophthalmology. 2021 09; 128(9):1346-1355. doi: 10.1016/j.ophtha.2021.03.009. [PMID: 33711379]
  • Benedicte Lelievre, Anne-Charlotte Tellier, Gabriel Colonna, Benjamin Cohen, Yoann Cazaubon, Frederic Leccia, François Darrouzain, Marie Deguigne. High silver concentrations in biological samples following different exposures: Two case reports. Journal of trace elements in medicine and biology : organ of the Society for Minerals and Trace Elements (GMS). 2021 Sep; 67(?):126775. doi: 10.1016/j.jtemb.2021.126775. [PMID: 33984545]
  • Mark J Henderson, Kathleen A Trychta, Shyh-Ming Yang, Susanne Bäck, Adam Yasgar, Emily S Wires, Carina Danchik, Xiaokang Yan, Hideaki Yano, Lei Shi, Kuo-Jen Wu, Amy Q Wang, Dingyin Tao, Gergely Zahoránszky-Kőhalmi, Xin Hu, Xin Xu, David Maloney, Alexey V Zakharov, Ganesha Rai, Fumihiko Urano, Mikko Airavaara, Oksana Gavrilova, Ajit Jadhav, Yun Wang, Anton Simeonov, Brandon K Harvey. A target-agnostic screen identifies approved drugs to stabilize the endoplasmic reticulum-resident proteome. Cell reports. 2021 04; 35(4):109040. doi: 10.1016/j.celrep.2021.109040. [PMID: 33910017]
  • M Conde-Cid, R Cela-Dablanca, G Ferreira-Coelho, D Fernández-Calviño, A Núñez-Delgado, M J Fernández-Sanjurjo, M Arias-Estévez, E Álvarez-Rodríguez. Sulfadiazine, sulfamethazine and sulfachloropyridazine removal using three different porous materials: Pine bark, "oak ash" and mussel shell. Environmental research. 2021 04; 195(?):110814. doi: 10.1016/j.envres.2021.110814. [PMID: 33524329]
  • Rong Li, Tuoyu Zhou, Aman Khan, Zhenmin Ling, Monika Sharma, Pengya Feng, Gohar Ali, Irfan Saif, Haoyang Wang, Xiangkai Li, Pu Liu. Feed-additive of bioengineering strain with surface-displayed laccase degrades sulfadiazine in broiler manure and maintains intestinal flora structure. Journal of hazardous materials. 2021 03; 406(?):124440. doi: 10.1016/j.jhazmat.2020.124440. [PMID: 33302188]
  • Zahra Ahmadabadi, Mehdi Zarei, Jafar Yasrebi, Abdolmajid Ronaghi, Reza Ghasemi, Leila Sadegh Kasmaei, Elke Bloem, Ewald Schnug. The effect of bio/organic fertilizers on the phytotoxicity of sulfadiazine to Echium amoenum in a calcareous soil. Ecotoxicology and environmental safety. 2021 Jan; 208(?):111408. doi: 10.1016/j.ecoenv.2020.111408. [PMID: 33038728]
  • Ingrid Reiter-Owona, Harald Hlobil, Martin Enders, Ute Klarmann-Schulz, Barbara Gruetzmacher, Veronika Rilling, Achim Hoerauf, Justus G Garweg. Sulfadiazine plasma concentrations in women with pregnancy-acquired compared to ocular toxoplasmosis under pyrimethamine and sulfadiazine therapy: a case-control study. European journal of medical research. 2020 Nov; 25(1):59. doi: 10.1186/s40001-020-00458-7. [PMID: 33228795]
  • Sara de la Mata Navazo, Laura Butragueño Laiseca, María Slocker Barrio, Alicia Mata Fernández. [Sulphadiazine crystaluria in a patient with disseminated toxoplasmosis]. Anales de pediatria. 2020 Oct; 93(4):268-269. doi: 10.1016/j.anpedi.2019.10.006. [PMID: 31761682]
  • Vitória Loureiro Dos Louros, Carla Patrícia Silva, Helena Nadais, Marta Otero, Valdemar I Esteves, Diana L D Lima. Photodegradation of sulfadiazine in different aquatic environments - Evaluation of influencing factors. Environmental research. 2020 09; 188(?):109730. doi: 10.1016/j.envres.2020.109730. [PMID: 32516634]
  • Ting Luo, Shailendra Shakya, Priyanka Mittal, Xiaohong Ren, Tao Guo, Mubarak G Bello, Li Wu, Haiyan Li, Weifeng Zhu, Balmukunda Regmi, Jiwen Zhang. Co-delivery of superfine nano-silver and solubilized sulfadiazine for enhanced antibacterial functions. International journal of pharmaceutics. 2020 Jun; 584(?):119407. doi: 10.1016/j.ijpharm.2020.119407. [PMID: 32389789]
  • M Conde-Cid, D Fernández-Calviño, M J Fernández-Sanjurjo, A Núñez-Delgado, E Álvarez-Rodríguez, M Arias-Estévez. Effects of pine bark amendment on the transport of sulfonamide antibiotics in soils. Chemosphere. 2020 Jun; 248(?):126041. doi: 10.1016/j.chemosphere.2020.126041. [PMID: 32028162]
  • Jayesh Patel, Sarat Kuppachi. AKI in a Patient with Cerebral Toxoplasmosis. Kidney360. 2020 Apr; 1(4):316-317. doi: 10.34067/kid.0000592019. [PMID: 35372923]
  • Luke P Robertson, Lindon W K Moodie, Darren C Holland, K Charlotte Jandér, Ulf Göransson. Sulfadiazine Masquerading as a Natural Product from Scilla madeirensis (Scilloideae). Journal of natural products. 2020 04; 83(4):1305-1308. doi: 10.1021/acs.jnatprod.0c00163. [PMID: 32208615]
  • Sabrine Afsa, Khaled Hamden, Pablo A Lara Martin, Hedi Ben Mansour. Occurrence of 40 pharmaceutically active compounds in hospital and urban wastewaters and their contribution to Mahdia coastal seawater contamination. Environmental science and pollution research international. 2020 Jan; 27(2):1941-1955. doi: 10.1007/s11356-019-06866-5. [PMID: 31768956]
  • Ying He, Ting Yao, Shuo Tan, Bingqi Yu, Kailin Liu, Lifeng Hu, Kun Luo, Min Liu, Xiangying Liu, Lianyang Bai. Effects of pH and gallic acid on the adsorption of two ionizable organic contaminants to rice straw-derived biochar-amended soils. Ecotoxicology and environmental safety. 2019 Nov; 184(?):109656. doi: 10.1016/j.ecoenv.2019.109656. [PMID: 31526920]
  • Tobie D Lee, Olivia W Lee, Kyle R Brimacombe, Lu Chen, Rajarshi Guha, Sabrina Lusvarghi, Bethilehem G Tebase, Carleen Klumpp-Thomas, Robert W Robey, Suresh V Ambudkar, Min Shen, Michael M Gottesman, Matthew D Hall. A High-Throughput Screen of a Library of Therapeutics Identifies Cytotoxic Substrates of P-glycoprotein. Molecular pharmacology. 2019 11; 96(5):629-640. doi: 10.1124/mol.119.115964. [PMID: 31515284]
  • João Cláudio da Costa Urbano, Ranny Beatriz de Carvalho Holanda Leite, Renan Leopoldo Pereira Castro, Clarice Maux Vianna da Silva, Joelma Maria de Araújo Andrade, Cláudio Bruno Silva de Oliveira, Vanessa Santos de Arruda Barbosa, Valter Ferreira de Andrade-Neto, Cecília Maria de Carvalho Xavier Holanda. Effect of toxoplasmic infection on the biodistribution of a brain radiopharmaceutical. International journal of radiation biology. 2019 11; 95(11):1547-1551. doi: 10.1080/09553002.2019.1642533. [PMID: 31290704]
  • Dapeng Wang, Xian Zhang, Changzhou Yan. Occurrence and removal of sulfonamides and their acetyl metabolites in a biological aerated filter (BAF) of wastewater treatment plant in Xiamen, South China. Environmental science and pollution research international. 2019 Nov; 26(32):33363-33372. doi: 10.1007/s11356-019-06311-7. [PMID: 31522397]
  • Chun-Xue Zhou, Yun Gan, Hany M Elsheikha, Xiao-Qing Chen, Hua Cong, Qing Liu, Xing-Quan Zhu. Sulfadiazine Sodium Ameliorates the Metabolomic Perturbation in Mice Infected with Toxoplasma gondii. Antimicrobial agents and chemotherapy. 2019 10; 63(10):. doi: 10.1128/aac.00312-19. [PMID: 31383652]
  • Nisha Sharma, Giorgio Arrigoni, Leonard Barnabas Ebinezer, Anna Rita Trentin, Cinzia Franchin, Sabrina Giaretta, Paolo Carletti, Sören Thiele-Bruhn, Rossella Ghisi, Antonio Masi. A proteomic and biochemical investigation on the effects of sulfadiazine in Arabidopsis thaliana. Ecotoxicology and environmental safety. 2019 Aug; 178(?):146-158. doi: 10.1016/j.ecoenv.2019.04.008. [PMID: 31002969]
  • Kaifeng Yu, Chi Sun, Bo Zhang, Muhammad Hassan, Yiliang He. Size-dependent adsorption of antibiotics onto nanoparticles in a field-scale wastewater treatment plant. Environmental pollution (Barking, Essex : 1987). 2019 May; 248(?):1079-1087. doi: 10.1016/j.envpol.2019.02.090. [PMID: 31091640]
  • Run Tian, Rong Zhang, Misbah Uddin, Xianliang Qiao, Jingwen Chen, Gege Gu. Uptake and metabolism of clarithromycin and sulfadiazine in lettuce. Environmental pollution (Barking, Essex : 1987). 2019 Apr; 247(?):1134-1142. doi: 10.1016/j.envpol.2019.02.009. [PMID: 30823342]
  • Iman Tabatabaei, Cristina Dal Bosco, Marta Bednarska, Stephanie Ruf, Jörg Meurer, Ralph Bock. A highly efficient sulfadiazine selection system for the generation of transgenic plants and algae. Plant biotechnology journal. 2019 03; 17(3):638-649. doi: 10.1111/pbi.13004. [PMID: 30144344]
  • Harini Bejjanki, Olanrewaju A Olaoye, Alfonso H Santos, Abhilash Koratala. Liver transplant, toxoplasmosis and kidney stones: connecting the dots. BMJ case reports. 2019 Feb; 12(2):. doi: 10.1136/bcr-2019-229197. [PMID: 30772835]
  • Gesine Pufal, Jörg Memmert, Sara Diana Leonhardt, Vanessa Minden. Negative bottom-up effects of sulfadiazine, but not penicillin and tetracycline, in soil substitute on plants and higher trophic levels. Environmental pollution (Barking, Essex : 1987). 2019 Feb; 245(?):531-544. doi: 10.1016/j.envpol.2018.11.008. [PMID: 30466072]
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