Talampicillin (BioDeep_00000008848)
代谢物信息卡片
化学式: C24H23N3O6S (481.13074980000005)
中文名称: 酞氨西林
谱图信息:
最多检出来源 () 0%
分子结构信息
SMILES: CC1(C(N2C(S1)C(C2=O)NC(=O)C(C3=CC=CC=C3)N)C(=O)OC4C5=CC=CC=C5C(=O)O4)C
InChI: InChI=1S/C24H23N3O6S/c1-24(2)17(22(31)33-23-14-11-7-6-10-13(14)21(30)32-23)27-19(29)16(20(27)34-24)26-18(28)15(25)12-8-4-3-5-9-12/h3-11,15-17,20,23H,25H2,1-2H3,(H,26,28)
描述信息
J - Antiinfectives for systemic use > J01 - Antibacterials for systemic use > J01C - Beta-lactam antibacterials, penicillins > J01CA - Penicillins with extended spectrum
D000890 - Anti-Infective Agents > D000900 - Anti-Bacterial Agents > D047090 - beta-Lactams
D000890 - Anti-Infective Agents > D000900 - Anti-Bacterial Agents > D010406 - Penicillins
D000890 - Anti-Infective Agents > D000900 - Anti-Bacterial Agents > D007769 - Lactams
C254 - Anti-Infective Agent > C258 - Antibiotic > C260 - Beta-Lactam Antibiotic
Same as: D08557
同义名列表
数据库引用编号
15 个数据库交叉引用编号
- ChEBI: CHEBI:9391
- KEGG: C11751
- KEGGdrug: D08557
- PubChem: 71447
- PubChem: 5373
- Metlin: METLIN610
- DrugBank: DB13814
- ChEMBL: CHEMBL1619785
- MeSH: Talampicillin
- CAS: 47747-56-8
- PMhub: MS000022550
- MetaboLights: MTBLC9391
- PubChem: 13916
- NIKKAJI: J9.701B
- RefMet: Talampicillin
分类词条
相关代谢途径
Reactome(0)
BioCyc(0)
PlantCyc(0)
代谢反应
0 个相关的代谢反应过程信息。
Reactome(0)
BioCyc(0)
WikiPathways(0)
Plant Reactome(0)
INOH(0)
PlantCyc(0)
COVID-19 Disease Map(0)
PathBank(0)
PharmGKB(0)
0 个相关的物种来源信息
在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：
- PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
- NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
- Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
- Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。
点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。
文献列表
- Mohammad M Ghahremanpour, Julian Tirado-Rives, Maya Deshmukh, Joseph A Ippolito, Chun-Hui Zhang, Israel Cabeza de Vaca, Maria-Elena Liosi, Karen S Anderson, William L Jorgensen. Identification of 14 Known Drugs as Inhibitors of the Main Protease of SARS-CoV-2.
ACS medicinal chemistry letters.
2020 Dec; 11(12):2526-2533. doi:
10.1021/acsmedchemlett.0c00521. [PMID: 33324471] - J M Ensink, A G Vulto, A S van Miert, J J Tukker, M B Winkel, M A Fluitman. Oral bioavailability and in vitro stability of pivampicillin, bacampicillin, talampicillin, and ampicillin in horses.
American journal of veterinary research.
1996 Jul; 57(7):1021-4. doi:
. [PMID: 8807014] - Y Akimoto, H Nishimura, M Komiya, K Kaneko, A Fujii, T Tamura. Ampicillin concentrations in human dental granuloma after a single oral administration of talampicillin.
Antimicrobial agents and chemotherapy.
1988 Apr; 32(4):566-7. doi:
10.1128/aac.32.4.566. [PMID: 3377465] - Y Akimoto, A Uda, H Omata, H Nishimura, M Komiya, K Kaneko, A Fujii, T Tamura. Ampicillin concentrations in human serum and periodontal membrane following a single oral administration of talampicillin.
General pharmacology.
1988; 19(4):515-6. doi:
10.1016/0306-3623(88)90156-5. [PMID: 3410274] - J Haginaka, J Wakai. Liquid chromatographic determination of ampicillin and its metabolites in human urine by postcolumn alkaline degradation.
The Journal of pharmacy and pharmacology.
1987 Jan; 39(1):5-8. doi:
10.1111/j.2042-7158.1987.tb07152.x. [PMID: 2880985] - K Fujita, T Sayama, S Abe, T Murayama, M Sugimoto, T Hara. [The duration of antibacterial treatment following transurethral prostatectomy].
The Japanese journal of antibiotics.
1985 Aug; 38(8):2149-54. doi:
NULL. [PMID: 3852896] - Y Akimoto, K Kaneko, A Fujii, T Tamura. Ampicillin concentrations in human serum, gingiva, mandibular bone, dental follicle, and dental pulp following a single oral dose of talampicillin.
Journal of oral and maxillofacial surgery : official journal of the American Association of Oral and Maxillofacial Surgeons.
1985 Apr; 43(4):270-6. doi:
10.1016/0278-2391(85)90286-1. [PMID: 3856643] - Y Akimoto, H Nishimura, M Komiya, T Shibata, K Kaneko, A Fujii, T Tamura. Concentrations of ampicillin and cefadroxil in human serum and mixed saliva following a single oral administration of talampicillin and cefadroxil, and relationships between serum and mixed saliva concentrations.
General pharmacology.
1985; 16(3):273-5. doi:
10.1016/0306-3623(85)90082-5. [PMID: 4018542] - N Mallo, F Dalet. Comparative pharmacoclinical evaluation between talampicillin and ampicillin in urinary infections.
Chemotherapy.
1981; 27(5):354-9. doi:
10.1159/000238004. [PMID: 7261688] - J M Hamilton-Miller, W Brumfitt. The bioavailability for four different commerically available brands of ampicillin compared with that of talampicillin.
The Journal of antimicrobial chemotherapy.
1979 Nov; 5(6):699-704. doi:
10.1093/jac/5.6.699. [PMID: 536354] - D J Jeffery, K H Jones, P F Langley. The metabolism of talampicillin in rat, dog and man.
Xenobiotica; the fate of foreign compounds in biological systems.
1978 Jul; 8(7):419-27. doi:
10.3109/00498257809070026. [PMID: 685291] - A Tachibana, K Ohtani, M Komiya, S Naito, C Shimizu, K Yano. [Talampicillin hydrochloride: Comparison with amoxicillin and ampicillin in the antibacterial activity and pharmacokinetics (author's transl)].
The Japanese journal of antibiotics.
1978 Mar; 31(3):166-76. doi:
NULL. [PMID: 246947] - K H Jones, P F Langley, L J Lees. Bioavailability and metabolism of talampicillin.
Chemotherapy.
1978; 24(4):217-26. doi:
10.1159/000237784. [PMID: 348415] - J Symonds, R H George. The effect of talampicillin on faecal flora.
The Journal of antimicrobial chemotherapy.
1978 Jan; 4(1):92-4. doi:
10.1093/jac/4.1.92. [PMID: 624697] - J P Clayton, M Cole, S W Elson, H Ferres. BRL.8988 (talampicillin), a well-absorbed oral form of ampicillin.
Antimicrobial agents and chemotherapy.
1974 Jun; 5(6):670-1. doi:
10.1128/aac.5.6.670. [PMID: 15825424]