Sphaeropsidin A (BioDeep_00000843871)
代谢物信息卡片
化学式: C20H26O5 (346.17801460000004)
中文名称:
谱图信息:
最多检出来源 () 0%
分子结构信息
SMILES: CC1(CCCC23C1C(C(=O)C4=CC(CCC42O)(C)C=C)(OC3=O)O)C
InChI: InChI=1S/C20H26O5/c1-5-17(4)9-10-19(23)12(11-17)13(21)20(24)14-16(2,3)7-6-8-18(14,19)15(22)25-20/h5,11,14,23-24H,1,6-10H2,2-4H3/t14-,17-,18-,19+,20+/m0/s1
描述信息
A natural product found in Smardaea species and Diplodia cupressi.
同义名列表
1 个代谢物同义名
数据库引用编号
5 个数据库交叉引用编号
- ChEBI: CHEBI:69494
- PubChem: 51361447
- ChEMBL: CHEMBL1834675
- CAS: 38991-80-9
- MetaboLights: MTBLC69494
分类词条
相关代谢途径
Reactome(0)
BioCyc(0)
PlantCyc(0)
代谢反应
0 个相关的代谢反应过程信息。
Reactome(0)
BioCyc(0)
WikiPathways(0)
Plant Reactome(0)
INOH(0)
PlantCyc(0)
COVID-19 Disease Map(0)
PathBank(0)
PharmGKB(0)
0 个相关的物种来源信息
在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：
- PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
- NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
- Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
- Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。
点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。
文献列表
- Marco Masi, Roberta Di Lecce, Umberto Calice, Benedetto Teodoro Linaldeddu, Lucia Maddau, Stefano Superchi, Antonio Evidente. Diplofuranoxin, a disubstituted dihydrofuranone, was produced together with sphaeropsidin A and epi-sphaeropsidone by Diplodia subglobosa, an emerging ash (Fraxinus excelsior L.) pathogen in Europe.
Phytochemistry.
2022 Oct; 202(?):113302. doi:
10.1016/j.phytochem.2022.113302. [PMID: 35810877] - Maria Michela Salvatore, Ilaria Di Lelio, Marina DellaGreca, Rosario Nicoletti, Francesco Salvatore, Elia Russo, Gennaro Volpe, Andrea Becchimanzi, Alla Eddine Mahamedi, Akila Berraf-Tebbal, Anna Andolfi. Secondary Metabolites, including a New 5,6-Dihydropyran-2-One, Produced by the Fungus Diplodia corticola. Aphicidal Activity of the Main Metabolite, Sphaeropsidin A.
Molecules (Basel, Switzerland).
2022 Apr; 27(7):. doi:
10.3390/molecules27072327. [PMID: 35408726] - Alet E van der Westhuyzen, Aude Ingels, Rémi Rosière, Karim Amighi, Lukas Oberer, Kirk R Gustafson, Dongdong Wang, Antonio Evidente, Lucia Maddau, Marco Masi, André de Villiers, Ivan R Green, Walter Berger, Alexander Kornienko, Veronique Mathieu, Willem A L van Otterlo. Deciphering the chemical instability of sphaeropsidin A under physiological conditions - degradation studies and structural elucidation of the major metabolite.
Organic & biomolecular chemistry.
2020 10; 18(40):8147-8160. doi:
10.1039/d0ob01586e. [PMID: 33016969] - Véronique Mathieu, Aurélie Chantôme, Florence Lefranc, Alessio Cimmino, Walter Miklos, Verena Paulitschke, Thomas Mohr, Lucia Maddau, Alexander Kornienko, Walter Berger, Christophe Vandier, Antonio Evidente, Eric Delpire, Robert Kiss. Sphaeropsidin A shows promising activity against drug-resistant cancer cells by targeting regulatory volume increase.
Cellular and molecular life sciences : CMLS.
2015 Oct; 72(19):3731-46. doi:
10.1007/s00018-015-1902-6. [PMID: 25868554] - Antonio Evidente, Vittorio Venturi, Marco Masi, Giuliano Degrassi, Alessio Cimmino, Lucia Maddau, Anna Andolfi. In vitro antibacterial activity of sphaeropsidins and chemical derivatives toward Xanthomonas oryzae pv. oryzae, the causal agent of rice bacterial blight.
Journal of natural products.
2011 Dec; 74(12):2520-5. doi:
10.1021/np200625m. [PMID: 22124378]