Taxiresinol (BioDeep_00000729665)

   

natural product


代谢物信息卡片


4-[4-[(4-Hydroxy-3-methoxyphenyl)methyl]-3-(hydroxymethyl)oxolan-2-yl]benzene-1,2-diol

化学式: C19H22O6 (346.1416)
中文名称: 紫杉脂素
谱图信息: 最多检出来源 () 0%

分子结构信息

SMILES: COC1=C(C=CC(=C1)CC2COC(C2CO)C3=CC(=C(C=C3)O)O)O
InChI: InChI=1S/C19H22O6/c1-24-18-7-11(2-4-16(18)22)6-13-10-25-19(14(13)9-20)12-3-5-15(21)17(23)8-12/h2-5,7-8,13-14,19-23H,6,9-10H2,1H3

描述信息

A lignan that consists of tetrahydrofuran substituted by a 3,4-dihydroxyphenyl group at position 2, a hydroxymethyl group at position 3 and a 4-hydroxy-3-methoxybenzyl group at position 4. It has been isolated from Taxus yunnanensis.

同义名列表

9 个代谢物同义名

Taxiresinol; 4-[4-[(4-Hydroxy-3-methoxyphenyl)methyl]-3-(hydroxymethyl)oxolan-2-yl]benzene-1,2-diol; (+)-Taxiresinol; 4-((2S,3R,4R)-4-((4-hydroxy-3-methoxyphenyl)methyl)-3-(hydroxymethyl)oxolan-2-yl)benzene-1,2-diol; 4-((2S,3R,4R)-4-(4-hydroxy-3-methoxybenzyl)-3-(hydroxymethyl)tetrahydrofuran-2-yl)benzene-1,2-diol; 4-[(2S,3R,4R)-4-(4-hydroxy-3-methoxybenzyl)-3-(hydroxymethyl)tetrahydrofuran-2-yl]benzene-1,2-diol; 4-[(2S,3R,4R)-4-[(4-hydroxy-3-methoxyphenyl)methyl]-3-(hydroxymethyl)oxolan-2-yl]benzene-1,2-diol; 4-[Tetrahydro-4-[(4-hydroxy-3-methoxyphenyl)methyl]-3-hydroxymethylfuran-2-yl]-1,2-benzenediol; SNZZAHRDXCGWEM-CKFHNAJUSA-N



数据库引用编号

9 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(0)

BioCyc(0)

PlantCyc(0)

代谢反应

0 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

43 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：

  • PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。

亚细胞结构定位 关联基因列表


文献列表

  • Junko Koyama, Izumi Morita, Norihiro Kobayashi, Keiichi Hirai, Eriko Simamura, Takahiro Nobukawa, Shigetoshi Kadota. Antiallergic activity of aqueous extracts and constituents of Taxus yunnanensis. Biological & pharmaceutical bulletin. 2006 Nov; 29(11):2310-2. doi: 10.1248/bpb.29.2310. [PMID: 17077536]
  • A H Banskota, N T Nguyen, Y Tezuka, T Nobukawa, S Kadota. Hypoglycemic effects of the wood of Taxus yunnanensis on streptozotocin-induced diabetic rats and its active components. Phytomedicine : international journal of phytotherapy and phytopharmacology. 2006 Jan; 13(1-2):109-14. doi: 10.1016/j.phymed.2004.01.015. [PMID: 16360940]
  • Arjun H Banskota, Nhan Trung Nguyen, Yasuhiro Tezuka, Quan Le Tran, Takahiro Nobukawa, Youichi Kurashige, Masakiyo Sasahara, Shigetoshi Kadota. Secoisolariciresinol and isotaxiresinol inhibit tumor necrosis factor-alpha-dependent hepatic apoptosis in mice. Life sciences. 2004 Apr; 74(22):2781-92. doi: 10.1016/j.lfs.2003.10.021. [PMID: 15043992]
  • Ilhan Gurbuz, Nurgun Erdemoglu, Erdem Yesilada, Bilge Sener. Anti-ulcerogenic lignans from Taxus baccata L. Zeitschrift fur Naturforschung. C, Journal of biosciences. 2004 Mar; 59(3-4):233-6. doi: 10.1515/znc-2004-3-420. [PMID: 15241933]
  • Nhan Trung Nguyen, Arjun H Banskota, Yasuhiro Tezuka, Quan Le Tran, Takahiro Nobukawa, Youichi Kurashige, Masakiyo Sasahara, Shigetoshi Kadota. Hepatoprotective effect of taxiresinol and (7'R)-7'-hydroxylariciresinol on D-galactosamine and lipopolysaccharide-induced liver injury in mice. Planta medica. 2004 Jan; 70(1):29-33. doi: 10.1055/s-2004-815451. [PMID: 14765289]
  • Sunil K Chattopadhyay, T R Santha Kumar, Prakas R Maulik, Sachin Srivastava, Ankur Garg, Ashoke Sharon, Arvind S Negi, Suman Preet S Khanuja. Absolute configuration and anticancer activity of taxiresinol and related lignans of Taxus wallichiana. Bioorganic & medicinal chemistry. 2003 Nov; 11(23):4945-8. doi: 10.1016/j.bmc.2003.09.010. [PMID: 14604656]