ST 27:2;O (BioDeep_00000636705)
Secondary id: BioDeep_00000014583, BioDeep_00000016930, BioDeep_00000055068, BioDeep_00001870865, BioDeep_00001871929, BioDeep_00001872469
代谢物信息卡片
化学式: C27H44O (384.3391974)
中文名称: 5-胆甾烯-3-酮, 光甾醇 3
谱图信息:
最多检出来源 Homo sapiens(blood) 0.44%
分子结构信息
SMILES: C12=CC=C3C[C@@H](O)CC[C@@]3(C)[C@]1([H])CC[C@]1(C)[C@@]([H])([C@]([H])(C)CCCC(C)C)CC[C@@]21[H]
InChI: InChI=1S/C27H44O/c1-18(2)7-6-8-19(3)23-11-12-24-22-10-9-20-17-21(28)13-15-26(20,4)25(22)14-16-27(23,24)5/h18-20,23-24H,6-17H2,1-5H3/t19-,20+,23-,24+,26+,27-/m1/s1
描述信息
同义名列表
30 个代谢物同义名
(25S)-24S,26-cyclo-5alpha-cholestan-3beta-ol; 22-dehydro-24,26-cyclocholestanol; ST 27:2;O; (25S)-24S,26-cyclocholest-5-en-3beta-ol; 24,26-cyclocholesterol; 27-nor-(24R)-methylcholest-5,22E-dien-3beta-ol; 27-nor-ergosta-5,22E-dien-3beta-ol; Cholesta-4,6-dien-3beta-ol; 4,6-cholestadien-3beta-ol; 4,6-cholestadienol; Cholesta-5, 20(22)E-dien-3beta-ol; 5, 20(22)-cholestadien-3beta-ol; 5, 20(22)-cholestadienol; (5alpha)-cholest-1-en-3-one; 1-(5alpha)-cholesten-3-one; 1-(5alpha)-cholestenone; cholesta-5,22Z-dien-3beta-ol; 22Z-dehydrocholesterol; Cholestenone (delta 5); cholest-5-en-3-one; 3-ketocholesterol; Lumisterol 3; 5alpha-cholesta-8-en-3-one; 5alpha-cholest-8-en-3-one; (3beta,5alpha)-cholesta-7,24-dien-3-ol; 5alpha-cholesta-7,24-dien-3beta-ol; cholesta-7,24-dien-3-ol; cholesta-5,22E-dien-3beta-ol; Cholesta-5,22-dien-3beta-ol; 22-Dehydrocholesterol
数据库引用编号
40 个数据库交叉引用编号
- ChEBI: CHEBI:173047
- ChEBI: CHEBI:63906
- ChEBI: CHEBI:166836
- ChEBI: CHEBI:87056
- ChEBI: CHEBI:16290
- ChEBI: CHEBI:156155
- KEGG: C90310
- PubChem: 52931489
- PubChem: 14680449
- PubChem: 21670844
- PubChem: 21598310
- PubChem: 11783955
- PubChem: 52931330
- PubChem: 9908107
- PubChem: 111049
- PubChem: 44263324
- PubChem: 5459827
- PubChem: 5283661
- ChEMBL: CHEMBL307301
- ChEMBL: CHEMBL4163100
- ChEMBL: CHEMBL1836651
- LipidMAPS: LMST01110015
- LipidMAPS: LMST01110008
- LipidMAPS: LMST01031048
- LipidMAPS: LMST01010351
- LipidMAPS: LMST01010350
- LipidMAPS: LMST01010349
- LipidMAPS: LMST01010317
- LipidMAPS: LMST01010248
- LipidMAPS: LMST01010247
- LipidMAPS: LMST01010239
- LipidMAPS: LMST01010206
- LipidMAPS: LMST01010095
- CAS: 601-54-7
- CAS: 5226-01-7
- CAS: 651-54-7
- CAS: 26033-10-3
- CAS: 34347-28-9
- RefMet: 3-Ketocholesterol
- RefMet: ST 27:2;O
分类词条
相关代谢途径
BioCyc(8)
- superpathway of cholesterol degradation II (cholesterol dehydrogenase)
- superpathway of cholesterol degradation I (cholesterol oxidase)
- cholesterol degradation to androstenedione I (cholesterol oxidase)
- cholesterol degradation to androstenedione II (cholesterol dehydrogenase)
- cholesterol biosynthesis I
- cholesterol biosynthesis III (via desmosterol)
- superpathway of cholesterol biosynthesis
- cholesterol biosynthesis II (via 24,25-dihydrolanosterol)
代谢反应
0 个相关的代谢反应过程信息。
Reactome(0)
BioCyc(0)
WikiPathways(0)
Plant Reactome(0)
INOH(0)
PlantCyc(0)
COVID-19 Disease Map(0)
PathBank(0)
PharmGKB(0)
1 个相关的物种来源信息
- 9606 - Homo sapiens: 10.1007/S11306-016-1051-4
在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有:
- PubMed: 来源于PubMed文献库中的文献信息,我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表,这个列表按照代谢物同时出现的文献数量降序排序,取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
- NCBI Taxonomy: 通过文献数据挖掘,得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序,取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
- Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
- Chemical Reaction: 在化学反应过程中,存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。
点击图上的相关代谢物的名称,可以跳转到相关代谢物的信息页面。
文献列表
- Christoph Müller, Sandra Hemmers, Nicholas Bartl, Alois Plodek, Andreas Körner, Valbona Mirakaj, Martin Giera, Franz Bracher. New chemotype of selective and potent inhibitors of human delta 24-dehydrocholesterol reductase.
European journal of medicinal chemistry.
2017 Nov; 140(?):305-320. doi:
10.1016/j.ejmech.2017.08.011
. [PMID: 28964935] - Montserrat Serra, Xavier Matabosch, Lee Ying, Gordon Watson, Cedric Shackleton. Hair and skin sterols in normal mice and those with deficient dehydrosterol reductase (DHCR7), the enzyme associated with Smith-Lemli-Opitz syndrome.
The Journal of steroid biochemistry and molecular biology.
2010 Nov; 122(5):318-25. doi:
10.1016/j.jsbmb.2010.08.006
. [PMID: 20804844] - Jana Sánchez-Wandelmer, Alberto Dávalos, Emilio Herrera, Martin Giera, Sonia Cano, Gema de la Peña, Miguel A Lasunción, Rebeca Busto. Inhibition of cholesterol biosynthesis disrupts lipid raft/caveolae and affects insulin receptor activation in 3T3-L1 preadipocytes.
Biochimica et biophysica acta.
2009 Sep; 1788(9):1731-9. doi:
10.1016/j.bbamem.2009.05.002
. [PMID: 19433058] - K Suzuki, T Shimizu, T Nakata. The cholesterol metabolite cholest-4-en-3-one and its 3-oxo derivatives suppress body weight gain, body fat accumulation and serum lipid concentration in mice.
Bioorganic & medicinal chemistry letters.
1998 Aug; 8(16):2133-8. doi:
10.1016/s0960-894x(98)00362-x
. [PMID: 9873500] - C Rujanavech, D F Silbert. LM cell growth and membrane lipid adaptation to sterol structure.
The Journal of biological chemistry.
1986 Jun; 261(16):7196-203. doi:
. [PMID: 3711084]