4-Amino-5-hydroxymethyl-2-methylpyrimidine (BioDeep_00000004646)
Secondary id: BioDeep_00001868584
human metabolite PANOMIX_OTCML-2023 blood metabolite Volatile Flavor Compounds
代谢物信息卡片
4-Amino-2-methyl-5-hydroxymethylpyrimidine
化学式: C6H9N3O (139.0745584)
中文名称: 4-氨基-2-甲基-5-嘧啶甲醇, 4-氨基-5-羟基甲基-2-甲基嘧啶
谱图信息:
最多检出来源 Homo sapiens(blood) 0.09%
分子结构信息
SMILES: c1c(c(nc(n1)C)N)CO
InChI: InChI=1S/C6H9N3O/c1-4-8-2-5(3-10)6(7)9-4/h2,10H,3H2,1H3,(H2,7,8,9)
描述信息
Hydroxymethylpyrimidine, also known as pyramine or toxopyrimidine, is a member of the class of compounds known as hydropyrimidines. Hydropyrimidines are compounds containing a hydrogenated pyrimidine ring (i.e. containing less than the maximum number of double bonds.). Hydroxymethylpyrimidine is soluble (in water) and a very weakly acidic compound (based on its pKa). Hydroxymethylpyrimidine can be found in a number of food items such as mexican oregano, sugar apple, tronchuda cabbage, and cinnamon, which makes hydroxymethylpyrimidine a potential biomarker for the consumption of these food products. Hydroxymethylpyrimidine exists in E.coli (prokaryote) and yeast (eukaryote).
同义名列表
14 个代谢物同义名
4-Amino-2-methyl-5-hydroxymethylpyrimidine; 4-Amino-5-hydroxymethyl-2-methylpyrimidine; 2-Methyl-4-amino-5-hydroxymethylpyrimidine; (4-amino-2-methylpyrimidin-5-yl)methanol; (4-Amino-2-methyl-5-pyrimidinyl)methanol; 4-Amino-2-methyl-5-pyrimidinemethanol; hydroxymethylpyrimidine; Atoxopyrimidine; Toxopyrimidine; Pyramine; Pyramin; HMP CPD; HMP; 4-Amino-5-hydroxymethyl-2-methylpyrimidine
数据库引用编号
22 个数据库交叉引用编号
- ChEBI: CHEBI:16892
- KEGG: C01279
- PubChem: 777
- HMDB: HMDB0247327
- Metlin: METLIN3265
- DrugBank: DB02022
- ChEMBL: CHEMBL1233354
- Wikipedia: 4-Amino-5-hydroxymethyl-2-methylpyrimidine
- MetaCyc: HMP
- KNApSAcK: C00007494
- foodb: FDB030912
- chemspider: 756
- CAS: 73-67-6
- PMhub: MS000017190
- PubChem: 4498
- PDB-CCD: HMH
- 3DMET: B00273
- NIKKAJI: J544.797F
- RefMet: 4-Amino-5-hydroxymethyl-2-methylpyrimidine
- KNApSAcK: 16892
- LOTUS: LTS0182824
- wikidata: Q27093111
分类词条
相关代谢途径
Reactome(0)
PlantCyc(0)
代谢反应
248 个相关的代谢反应过程信息。
Reactome(0)
BioCyc(62)
- thiamine salvage IV (yeast):
H2O + thiamine ⟶ 4-amino-2-methyl-5-pyrimidinemethanol + 5-(2-hydroxyethyl)-4-methylthiazole + H+ - base-degraded thiamine salvage:
H2O + aminomethylpyrimidine ⟶ 4-amino-2-methyl-5-pyrimidinemethanol + ammonium - hydroxymethylpyrimidine salvage:
4-amino-2-methyl-5-pyrimidinemethanol + ATP ⟶ ADP + H+ + HMP-P - thiamine formation from pyrithiamine and oxythiamine (yeast):
A + H2O + pyrithiamine ⟶ 2-(2-methylpyridin-3-yl)ethanol + 4-amino-2-methyl-5-pyrimidinemethanol + A(H2) - thiamine salvage II:
4-amino-2-methyl-5-pyrimidinemethanol + ATP ⟶ ADP + H+ + HMP-P - hydroxymethylpyrimidine salvage:
4-amino-2-methyl-5-pyrimidinemethanol + ATP ⟶ ADP + H+ + HMP-P - thiamine salvage II:
5-(2-hydroxyethyl)-4-methylthiazole + ATP ⟶ 4-methyl-5-(2-phosphooxyethyl)thiazole + ADP + H+ - thiamin salvage IV:
5-(2-hydroxyethyl)-4-methylthiazole + ATP ⟶ 4-methyl-5-(2-phosphooxyethyl)thiazole + ADP + H+ - base-degraded thiamin salvage:
H2O + aminomethylpyrimidine ⟶ 4-amino-2-methyl-5-pyrimidinemethanol + ammonium - hydroxymethylpyrimidine salvage:
4-amino-2-methyl-5-pyrimidinemethanol + ATP ⟶ ADP + H+ + HMP-P - thiamin formation from pyrithiamine and oxythiamine:
5-(2-hydroxyethyl)-4-methylthiazole + ATP ⟶ 4-methyl-5-(2-phosphooxyethyl)thiazole + ADP + H+ - thiamine salvage IV (yeast):
4-amino-2-methyl-5-pyrimidinemethanol + ATP ⟶ ADP + H+ + HMP-P - hydroxymethylpyrimidine salvage:
4-amino-2-methyl-5-pyrimidinemethanol + ATP ⟶ ADP + H+ + HMP-P - thiamine salvage II:
5-(2-hydroxyethyl)-4-methylthiazole + ATP ⟶ 4-methyl-5-(2-phosphooxyethyl)thiazole + ADP + H+ - hydroxymethylpyrimidine salvage:
4-amino-2-methyl-5-pyrimidinemethanol + ATP ⟶ ADP + H+ + HMP-P - thiamin salvage II:
4-methyl-5-(β-hydroxyethyl)thiazole + ATP ⟶ 4-methyl-5-(2-phosphonooxyethyl)thiazole + ADP + H+ - hydroxymethylpyrimidine salvage:
ATP + hydroxymethylpyrimidine ⟶ ADP + H+ + HMP-P - hydroxymethylpyrimidine salvage:
4-amino-2-methyl-5-pyrimidinemethanol + ATP ⟶ ADP + H+ + HMP-P - thiamine salvage II:
5-(2-hydroxyethyl)-4-methylthiazole + ATP ⟶ 4-methyl-5-(2-phosphonooxyethyl)thiazole + ADP + H+ - hydroxymethylpyrimidine salvage:
ATP + hydroxymethylpyrimidine ⟶ ADP + H+ + HMP-P - thiamin salvage II:
4-methyl-5-(β-hydroxyethyl)thiazole + ATP ⟶ 4-methyl-5-(2-phosphonooxyethyl)thiazole + ADP + H+ - hydroxymethylpyrimidine salvage:
ATP + hydroxymethylpyrimidine ⟶ ADP + H+ + HMP-P - thiamin salvage II:
4-methyl-5-(β-hydroxyethyl)thiazole + ATP ⟶ 4-methyl-5-(2-phosphonooxyethyl)thiazole + ADP + H+ - thiamin salvage II:
4-methyl-5-(β-hydroxyethyl)thiazole + ATP ⟶ 4-methyl-5-(2-phosphonooxyethyl)thiazole + ADP + H+ - hydroxymethylpyrimidine salvage:
ATP + hydroxymethylpyrimidine ⟶ 4-amino-2-methyl-5-phosphomethylpyrimidine + ADP + H+ - thiamine salvage II:
5-(2-hydroxyethyl)-4-methylthiazole + ATP ⟶ 4-methyl-5-(2-phosphooxyethyl)thiazole + ADP + H+ - hydroxymethylpyrimidine salvage:
4-amino-2-methyl-5-pyrimidinemethanol + ATP ⟶ ADP + H+ + HMP-P - thiamine salvage II:
4-amino-2-methyl-5-pyrimidinemethanol + ATP ⟶ ADP + H+ + HMP-P - hydroxymethylpyrimidine salvage:
4-amino-2-methyl-5-pyrimidinemethanol + ATP ⟶ ADP + H+ + HMP-P - thiamine salvage II:
5-(2-hydroxyethyl)-4-methylthiazole + ATP ⟶ 4-methyl-5-(2-phosphooxyethyl)thiazole + ADP + H+ - base-degraded thiamine salvage:
H2O + aminomethylpyrimidine ⟶ 4-amino-2-methyl-5-pyrimidinemethanol + ammonium - hydroxymethylpyrimidine salvage:
4-amino-2-methyl-5-pyrimidinemethanol + ATP ⟶ ADP + H+ + HMP-P - hydroxymethylpyrimidine salvage:
4-amino-2-methyl-5-pyrimidinemethanol + ATP ⟶ ADP + H+ + HMP-P - hydroxymethylpyrimidine salvage:
ATP + hydroxymethylpyrimidine ⟶ 4-amino-2-methyl-5-phosphomethylpyrimidine + ADP + H+ - thiamin salvage II:
4-methyl-5-(β-hydroxyethyl)thiazole + ATP ⟶ 4-methyl-5-(2-phosphonooxyethyl)thiazole + ADP + H+ - base-degraded thiamin salvage:
H2O + aminomethylpyrimidine ⟶ H+ + ammonia + hydroxymethylpyrimidine - hydroxymethylpyrimidine salvage:
ATP + hydroxymethylpyrimidine ⟶ 4-amino-2-methyl-5-phosphomethylpyrimidine + ADP + H+ - thiamin salvage II:
4-methyl-5-(β-hydroxyethyl)thiazole + ATP ⟶ 4-methyl-5-(2-phosphonooxyethyl)thiazole + ADP + H+ - hydroxymethylpyrimidine salvage:
4-amino-2-methyl-5-pyrimidinemethanol + ATP ⟶ ADP + H+ + HMP-P - thiamine salvage II:
5-(2-hydroxyethyl)-4-methylthiazole + ATP ⟶ 4-methyl-5-(2-phosphooxyethyl)thiazole + ADP + H+ - hydroxymethylpyrimidine salvage:
ATP + hydroxymethylpyrimidine ⟶ ADP + H+ + HMP-P - thiamin salvage II:
4-methyl-5-(β-hydroxyethyl)thiazole + ATP ⟶ 4-methyl-5-(2-phosphonooxyethyl)thiazole + ADP + H+ - thiamine formation from pyrithiamine and oxythiamine (yeast):
H2O + oxythiamine ⟶ 5-(2-hydroxyethyl)-4-methylthiazole + 5-(hydroxymethyl)-2-methyl-4(1H)-pyrimidinone + H+ - base-degraded thiamine salvage:
H2O + aminomethylpyrimidine ⟶ 4-amino-2-methyl-5-pyrimidinemethanol + ammonium - hydroxymethylpyrimidine salvage:
4-amino-2-methyl-5-pyrimidinemethanol + ATP ⟶ ADP + H+ + HMP-P - thiamine salvage II:
5-(2-hydroxyethyl)-4-methylthiazole + ATP ⟶ 4-methyl-5-(2-phosphooxyethyl)thiazole + ADP + H+ - thiamine salvage IV (yeast):
5-(2-hydroxyethyl)-4-methylthiazole + ATP ⟶ 4-methyl-5-(2-phosphooxyethyl)thiazole + ADP + H+ - hydroxymethylpyrimidine salvage:
4-amino-2-methyl-5-pyrimidinemethanol + ATP ⟶ ADP + H+ + HMP-P - thiamine salvage II:
5-(2-hydroxyethyl)-4-methylthiazole + ATP ⟶ 4-methyl-5-(2-phosphooxyethyl)thiazole + ADP + H+ - thiamine salvage II:
5-(2-hydroxyethyl)-4-methylthiazole + ATP ⟶ 4-methyl-5-(2-phosphooxyethyl)thiazole + ADP + H+ - hydroxymethylpyrimidine salvage:
4-amino-2-methyl-5-pyrimidinemethanol + ATP ⟶ ADP + H+ + HMP-P - hydroxymethylpyrimidine salvage:
4-amino-2-methyl-5-pyrimidinemethanol + ATP ⟶ ADP + H+ + HMP-P - thiamine salvage II:
5-(2-hydroxyethyl)-4-methylthiazole + ATP ⟶ 4-methyl-5-(2-phosphooxyethyl)thiazole + ADP + H+ - hydroxymethylpyrimidine salvage:
4-amino-2-methyl-5-pyrimidinemethanol + ATP ⟶ ADP + H+ + HMP-P - thiamine salvage II:
5-(2-hydroxyethyl)-4-methylthiazole + ATP ⟶ 4-methyl-5-(2-phosphooxyethyl)thiazole + ADP + H+ - hydroxymethylpyrimidine salvage:
4-amino-2-methyl-5-pyrimidinemethanol + ATP ⟶ ADP + H+ + HMP-P - thiamine salvage II:
5-(2-hydroxyethyl)-4-methylthiazole + ATP ⟶ 4-methyl-5-(2-phosphooxyethyl)thiazole + ADP + H+ - hydroxymethylpyrimidine salvage:
4-amino-2-methyl-5-pyrimidinemethanol + ATP ⟶ ADP + H+ + HMP-P - thiamine salvage II:
5-(2-hydroxyethyl)-4-methylthiazole + ATP ⟶ 4-methyl-5-(2-phosphooxyethyl)thiazole + ADP + H+ - base-degraded thiamine salvage:
H2O + aminomethylpyrimidine ⟶ 4-amino-2-methyl-5-pyrimidinemethanol + ammonium - hydroxymethylpyrimidine salvage:
4-amino-2-methyl-5-pyrimidinemethanol + ATP ⟶ ADP + H+ + HMP-P - thiamine salvage II:
5-(2-hydroxyethyl)-4-methylthiazole + ATP ⟶ 4-methyl-5-(2-phosphooxyethyl)thiazole + ADP + H+
WikiPathways(0)
Plant Reactome(3)
- Metabolism and regulation:
ATP + CoA + propionate ⟶ AMP + PPi + PROP-CoA - Cofactor biosyntheses:
2OG + L-Val ⟶ KIV + L-Glu - Thiamin biosynthesis:
5-(2-hydroxyethyl)-4-methylthiazole + ATP ⟶ 4-methyl-5-(2-phosphonooxyethyl)thiazole + ADP
INOH(0)
PlantCyc(182)
- hydroxymethylpyrimidine salvage:
4-amino-2-methyl-5-pyrimidinemethanol + ATP ⟶ ADP + H+ + HMP-P - hydroxymethylpyrimidine salvage:
4-amino-2-methyl-5-pyrimidinemethanol + ATP ⟶ ADP + H+ + HMP-P - hydroxymethylpyrimidine salvage:
4-amino-2-methyl-5-pyrimidinemethanol + ATP ⟶ ADP + H+ + HMP-P - hydroxymethylpyrimidine salvage:
4-amino-2-methyl-5-pyrimidinemethanol + ATP ⟶ ADP + H+ + HMP-P - hydroxymethylpyrimidine salvage:
4-amino-2-methyl-5-pyrimidinemethanol + ATP ⟶ ADP + H+ + HMP-P - thiamine salvage IV (yeast):
4-amino-2-methyl-5-pyrimidinemethanol + ATP ⟶ ADP + H+ + HMP-P - hydroxymethylpyrimidine salvage:
4-amino-2-methyl-5-pyrimidinemethanol + ATP ⟶ ADP + H+ + HMP-P - hydroxymethylpyrimidine salvage:
4-amino-2-methyl-5-pyrimidinemethanol + ATP ⟶ ADP + H+ + HMP-P - hydroxymethylpyrimidine salvage:
4-amino-2-methyl-5-pyrimidinemethanol + ATP ⟶ ADP + H+ + HMP-P - thiamine formation from pyrithiamine and oxythiamine (yeast):
H2O + oxythiamine ⟶ 5-(2-hydroxyethyl)-4-methylthiazole + 5-(hydroxymethyl)-2-methyl-4(1H)-pyrimidinone + H+ - hydroxymethylpyrimidine salvage:
4-amino-2-methyl-5-pyrimidinemethanol + ATP ⟶ ADP + H+ + HMP-P - hydroxymethylpyrimidine salvage:
4-amino-2-methyl-5-pyrimidinemethanol + ATP ⟶ ADP + H+ + HMP-P - hydroxymethylpyrimidine salvage:
4-amino-2-methyl-5-pyrimidinemethanol + ATP ⟶ ADP + H+ + HMP-P - hydroxymethylpyrimidine salvage:
4-amino-2-methyl-5-pyrimidinemethanol + ATP ⟶ ADP + H+ + HMP-P - thiamine formation from pyrithiamine and oxythiamine (yeast):
H2O + oxythiamine ⟶ 5-(2-hydroxyethyl)-4-methylthiazole + 5-(hydroxymethyl)-2-methyl-4(1H)-pyrimidinone + H+ - hydroxymethylpyrimidine salvage:
4-amino-2-methyl-5-pyrimidinemethanol + ATP ⟶ ADP + H+ + HMP-P - hydroxymethylpyrimidine salvage:
4-amino-2-methyl-5-pyrimidinemethanol + ATP ⟶ ADP + H+ + HMP-P - hydroxymethylpyrimidine salvage:
4-amino-2-methyl-5-pyrimidinemethanol + ATP ⟶ ADP + H+ + HMP-P - hydroxymethylpyrimidine salvage:
4-amino-2-methyl-5-pyrimidinemethanol + ATP ⟶ ADP + H+ + HMP-P - hydroxymethylpyrimidine salvage:
4-amino-2-methyl-5-pyrimidinemethanol + ATP ⟶ ADP + H+ + HMP-P - hydroxymethylpyrimidine salvage:
4-amino-2-methyl-5-pyrimidinemethanol + ATP ⟶ ADP + H+ + HMP-P - hydroxymethylpyrimidine salvage:
4-amino-2-methyl-5-pyrimidinemethanol + ATP ⟶ ADP + H+ + HMP-P - thiamine formation from pyrithiamine and oxythiamine (yeast):
H2O + oxythiamine ⟶ 5-(2-hydroxyethyl)-4-methylthiazole + 5-(hydroxymethyl)-2-methyl-4(1H)-pyrimidinone + H+ - hydroxymethylpyrimidine salvage:
4-amino-2-methyl-5-pyrimidinemethanol + ATP ⟶ ADP + H+ + HMP-P - hydroxymethylpyrimidine salvage:
4-amino-2-methyl-5-pyrimidinemethanol + ATP ⟶ ADP + H+ + HMP-P - hydroxymethylpyrimidine salvage:
4-amino-2-methyl-5-pyrimidinemethanol + ATP ⟶ ADP + H+ + HMP-P - hydroxymethylpyrimidine salvage:
4-amino-2-methyl-5-pyrimidinemethanol + ATP ⟶ ADP + H+ + HMP-P - hydroxymethylpyrimidine salvage:
4-amino-2-methyl-5-pyrimidinemethanol + ATP ⟶ ADP + H+ + HMP-P - hydroxymethylpyrimidine salvage:
4-amino-2-methyl-5-pyrimidinemethanol + ATP ⟶ ADP + H+ + HMP-P - hydroxymethylpyrimidine salvage:
4-amino-2-methyl-5-pyrimidinemethanol + ATP ⟶ ADP + H+ + HMP-P - hydroxymethylpyrimidine salvage:
4-amino-2-methyl-5-pyrimidinemethanol + ATP ⟶ ADP + H+ + HMP-P - hydroxymethylpyrimidine salvage:
4-amino-2-methyl-5-pyrimidinemethanol + ATP ⟶ ADP + H+ + HMP-P - hydroxymethylpyrimidine salvage:
4-amino-2-methyl-5-pyrimidinemethanol + ATP ⟶ ADP + H+ + HMP-P - hydroxymethylpyrimidine salvage:
4-amino-2-methyl-5-pyrimidinemethanol + ATP ⟶ ADP + H+ + HMP-P - hydroxymethylpyrimidine salvage:
4-amino-2-methyl-5-pyrimidinemethanol + ATP ⟶ ADP + H+ + HMP-P - thiamine salvage II:
5-(2-hydroxyethyl)-4-methylthiazole + ATP ⟶ 4-methyl-5-(2-phosphooxyethyl)thiazole + ADP + H+ - thiamine salvage IV (yeast):
5-(2-hydroxyethyl)-4-methylthiazole + ATP ⟶ 4-methyl-5-(2-phosphooxyethyl)thiazole + ADP + H+ - hydroxymethylpyrimidine salvage:
4-amino-2-methyl-5-pyrimidinemethanol + ATP ⟶ ADP + H+ + HMP-P - hydroxymethylpyrimidine salvage:
4-amino-2-methyl-5-pyrimidinemethanol + ATP ⟶ ADP + H+ + HMP-P - hydroxymethylpyrimidine salvage:
4-amino-2-methyl-5-pyrimidinemethanol + ATP ⟶ ADP + H+ + HMP-P - hydroxymethylpyrimidine salvage:
4-amino-2-methyl-5-pyrimidinemethanol + ATP ⟶ ADP + H+ + HMP-P - hydroxymethylpyrimidine salvage:
4-amino-2-methyl-5-pyrimidinemethanol + ATP ⟶ ADP + H+ + HMP-P - hydroxymethylpyrimidine salvage:
4-amino-2-methyl-5-pyrimidinemethanol + ATP ⟶ ADP + H+ + HMP-P - hydroxymethylpyrimidine salvage:
4-amino-2-methyl-5-pyrimidinemethanol + ATP ⟶ ADP + H+ + HMP-P - hydroxymethylpyrimidine salvage:
4-amino-2-methyl-5-pyrimidinemethanol + ATP ⟶ ADP + H+ + HMP-P - hydroxymethylpyrimidine salvage:
4-amino-2-methyl-5-pyrimidinemethanol + ATP ⟶ ADP + H+ + HMP-P - hydroxymethylpyrimidine salvage:
4-amino-2-methyl-5-pyrimidinemethanol + ATP ⟶ ADP + H+ + HMP-P - hydroxymethylpyrimidine salvage:
4-amino-2-methyl-5-pyrimidinemethanol + ATP ⟶ ADP + H+ + HMP-P - hydroxymethylpyrimidine salvage:
4-amino-2-methyl-5-pyrimidinemethanol + ATP ⟶ ADP + H+ + HMP-P - hydroxymethylpyrimidine salvage:
4-amino-2-methyl-5-pyrimidinemethanol + ATP ⟶ ADP + H+ + HMP-P - hydroxymethylpyrimidine salvage:
4-amino-2-methyl-5-pyrimidinemethanol + ATP ⟶ ADP + H+ + HMP-P - hydroxymethylpyrimidine salvage:
4-amino-2-methyl-5-pyrimidinemethanol + ATP ⟶ ADP + H+ + HMP-P - hydroxymethylpyrimidine salvage:
4-amino-2-methyl-5-pyrimidinemethanol + ATP ⟶ ADP + H+ + HMP-P - hydroxymethylpyrimidine salvage:
4-amino-2-methyl-5-pyrimidinemethanol + ATP ⟶ ADP + H+ + HMP-P - hydroxymethylpyrimidine salvage:
4-amino-2-methyl-5-pyrimidinemethanol + ATP ⟶ ADP + H+ + HMP-P - hydroxymethylpyrimidine salvage:
4-amino-2-methyl-5-pyrimidinemethanol + ATP ⟶ ADP + H+ + HMP-P - hydroxymethylpyrimidine salvage:
4-amino-2-methyl-5-pyrimidinemethanol + ATP ⟶ ADP + H+ + HMP-P - hydroxymethylpyrimidine salvage:
4-amino-2-methyl-5-pyrimidinemethanol + ATP ⟶ ADP + H+ + HMP-P - hydroxymethylpyrimidine salvage:
4-amino-2-methyl-5-pyrimidinemethanol + ATP ⟶ ADP + H+ + HMP-P - thiamine formation from pyrithiamine and oxythiamine (yeast):
5-(2-hydroxyethyl)-4-methylthiazole + ATP ⟶ 4-methyl-5-(2-phosphooxyethyl)thiazole + ADP + H+ - hydroxymethylpyrimidine salvage:
4-amino-2-methyl-5-pyrimidinemethanol + ATP ⟶ ADP + H+ + HMP-P - thiamine formation from pyrithiamine and oxythiamine (yeast):
H2O + oxythiamine ⟶ 5-(2-hydroxyethyl)-4-methylthiazole + 5-(hydroxymethyl)-2-methyl-4(1H)-pyrimidinone + H+ - hydroxymethylpyrimidine salvage:
4-amino-2-methyl-5-pyrimidinemethanol + ATP ⟶ ADP + H+ + HMP-P - hydroxymethylpyrimidine salvage:
4-amino-2-methyl-5-pyrimidinemethanol + ATP ⟶ ADP + H+ + HMP-P - thiamine formation from pyrithiamine and oxythiamine (yeast):
H2O + oxythiamine ⟶ 5-(2-hydroxyethyl)-4-methylthiazole + 5-(hydroxymethyl)-2-methyl-4(1H)-pyrimidinone + H+ - hydroxymethylpyrimidine salvage:
4-amino-2-methyl-5-pyrimidinemethanol + ATP ⟶ ADP + H+ + HMP-P - hydroxymethylpyrimidine salvage:
4-amino-2-methyl-5-pyrimidinemethanol + ATP ⟶ ADP + H+ + HMP-P - hydroxymethylpyrimidine salvage:
4-amino-2-methyl-5-pyrimidinemethanol + ATP ⟶ ADP + H+ + HMP-P - hydroxymethylpyrimidine salvage:
4-amino-2-methyl-5-pyrimidinemethanol + ATP ⟶ ADP + H+ + HMP-P - hydroxymethylpyrimidine salvage:
4-amino-2-methyl-5-pyrimidinemethanol + ATP ⟶ ADP + H+ + HMP-P - thiamine formation from pyrithiamine and oxythiamine (yeast):
5-(2-hydroxyethyl)-4-methylthiazole + ATP ⟶ 4-methyl-5-(2-phosphooxyethyl)thiazole + ADP + H+ - hydroxymethylpyrimidine salvage:
4-amino-2-methyl-5-pyrimidinemethanol + ATP ⟶ ADP + H+ + HMP-P - hydroxymethylpyrimidine salvage:
4-amino-2-methyl-5-pyrimidinemethanol + ATP ⟶ ADP + H+ + HMP-P - hydroxymethylpyrimidine salvage:
4-amino-2-methyl-5-pyrimidinemethanol + ATP ⟶ ADP + H+ + HMP-P - hydroxymethylpyrimidine salvage:
4-amino-2-methyl-5-pyrimidinemethanol + ATP ⟶ ADP + H+ + HMP-P - thiamine salvage IV (yeast):
H2O + thiamine ⟶ 4-amino-2-methyl-5-pyrimidinemethanol + 5-(2-hydroxyethyl)-4-methylthiazole + H+ - hydroxymethylpyrimidine salvage:
4-amino-2-methyl-5-pyrimidinemethanol + ATP ⟶ ADP + H+ + HMP-P - thiamine formation from pyrithiamine and oxythiamine (yeast):
5-(2-hydroxyethyl)-4-methylthiazole + ATP ⟶ 4-methyl-5-(2-phosphooxyethyl)thiazole + ADP + H+ - hydroxymethylpyrimidine salvage:
4-amino-2-methyl-5-pyrimidinemethanol + ATP ⟶ ADP + H+ + HMP-P - hydroxymethylpyrimidine salvage:
4-amino-2-methyl-5-pyrimidinemethanol + ATP ⟶ ADP + H+ + HMP-P - hydroxymethylpyrimidine salvage:
4-amino-2-methyl-5-pyrimidinemethanol + ATP ⟶ ADP + H+ + HMP-P - hydroxymethylpyrimidine salvage:
4-amino-2-methyl-5-pyrimidinemethanol + ATP ⟶ ADP + H+ + HMP-P - hydroxymethylpyrimidine salvage:
4-amino-2-methyl-5-pyrimidinemethanol + ATP ⟶ ADP + H+ + HMP-P - hydroxymethylpyrimidine salvage:
4-amino-2-methyl-5-pyrimidinemethanol + ATP ⟶ ADP + H+ + HMP-P - hydroxymethylpyrimidine salvage:
4-amino-2-methyl-5-pyrimidinemethanol + ATP ⟶ ADP + H+ + HMP-P - hydroxymethylpyrimidine salvage:
4-amino-2-methyl-5-pyrimidinemethanol + ATP ⟶ ADP + H+ + HMP-P - hydroxymethylpyrimidine salvage:
4-amino-2-methyl-5-pyrimidinemethanol + ATP ⟶ ADP + H+ + HMP-P - hydroxymethylpyrimidine salvage:
4-amino-2-methyl-5-pyrimidinemethanol + ATP ⟶ ADP + H+ + HMP-P - hydroxymethylpyrimidine salvage:
4-amino-2-methyl-5-pyrimidinemethanol + ATP ⟶ ADP + H+ + HMP-P - hydroxymethylpyrimidine salvage:
4-amino-2-methyl-5-pyrimidinemethanol + ATP ⟶ ADP + H+ + HMP-P - hydroxymethylpyrimidine salvage:
4-amino-2-methyl-5-pyrimidinemethanol + ATP ⟶ ADP + H+ + HMP-P - hydroxymethylpyrimidine salvage:
4-amino-2-methyl-5-pyrimidinemethanol + ATP ⟶ ADP + H+ + HMP-P - hydroxymethylpyrimidine salvage:
4-amino-2-methyl-5-pyrimidinemethanol + ATP ⟶ ADP + H+ + HMP-P - hydroxymethylpyrimidine salvage:
4-amino-2-methyl-5-pyrimidinemethanol + ATP ⟶ ADP + H+ + HMP-P - hydroxymethylpyrimidine salvage:
4-amino-2-methyl-5-pyrimidinemethanol + ATP ⟶ ADP + H+ + HMP-P - hydroxymethylpyrimidine salvage:
4-amino-2-methyl-5-pyrimidinemethanol + ATP ⟶ ADP + H+ + HMP-P - thiamine salvage IV (yeast):
H2O + thiamine ⟶ 4-amino-2-methyl-5-pyrimidinemethanol + 5-(2-hydroxyethyl)-4-methylthiazole + H+ - hydroxymethylpyrimidine salvage:
4-amino-2-methyl-5-pyrimidinemethanol + ATP ⟶ ADP + H+ + HMP-P - hydroxymethylpyrimidine salvage:
4-amino-2-methyl-5-pyrimidinemethanol + ATP ⟶ ADP + H+ + HMP-P - hydroxymethylpyrimidine salvage:
4-amino-2-methyl-5-pyrimidinemethanol + ATP ⟶ ADP + H+ + HMP-P - hydroxymethylpyrimidine salvage:
4-amino-2-methyl-5-pyrimidinemethanol + ATP ⟶ ADP + H+ + HMP-P - hydroxymethylpyrimidine salvage:
4-amino-2-methyl-5-pyrimidinemethanol + ATP ⟶ ADP + H+ + HMP-P - hydroxymethylpyrimidine salvage:
4-amino-2-methyl-5-pyrimidinemethanol + ATP ⟶ ADP + H+ + HMP-P - hydroxymethylpyrimidine salvage:
4-amino-2-methyl-5-pyrimidinemethanol + ATP ⟶ ADP + H+ + HMP-P - hydroxymethylpyrimidine salvage:
4-amino-2-methyl-5-pyrimidinemethanol + ATP ⟶ ADP + H+ + HMP-P - hydroxymethylpyrimidine salvage:
4-amino-2-methyl-5-pyrimidinemethanol + ATP ⟶ ADP + H+ + HMP-P - hydroxymethylpyrimidine salvage:
4-amino-2-methyl-5-pyrimidinemethanol + ATP ⟶ ADP + H+ + HMP-P - thiamine formation from pyrithiamine and oxythiamine (yeast):
H2O + oxythiamine ⟶ 5-(2-hydroxyethyl)-4-methylthiazole + 5-(hydroxymethyl)-2-methyl-4(1H)-pyrimidinone + H+ - hydroxymethylpyrimidine salvage:
4-amino-2-methyl-5-pyrimidinemethanol + ATP ⟶ ADP + H+ + HMP-P - hydroxymethylpyrimidine salvage:
4-amino-2-methyl-5-pyrimidinemethanol + ATP ⟶ ADP + H+ + HMP-P - hydroxymethylpyrimidine salvage:
4-amino-2-methyl-5-pyrimidinemethanol + ATP ⟶ ADP + H+ + HMP-P - thiamine salvage IV (yeast):
5-(2-hydroxyethyl)-4-methylthiazole + ATP ⟶ 4-methyl-5-(2-phosphooxyethyl)thiazole + ADP + H+ - thiamine salvage IV (yeast):
H2O + thiamine ⟶ 4-amino-2-methyl-5-pyrimidinemethanol + 5-(2-hydroxyethyl)-4-methylthiazole + H+ - thiamine salvage IV (yeast):
H2O + thiamine ⟶ 4-amino-2-methyl-5-pyrimidinemethanol + 5-(2-hydroxyethyl)-4-methylthiazole + H+ - hydroxymethylpyrimidine salvage:
4-amino-2-methyl-5-pyrimidinemethanol + ATP ⟶ ADP + H+ + HMP-P - hydroxymethylpyrimidine salvage:
4-amino-2-methyl-5-pyrimidinemethanol + ATP ⟶ ADP + H+ + HMP-P - thiamine salvage IV (yeast):
5-(2-hydroxyethyl)-4-methylthiazole + ATP ⟶ 4-methyl-5-(2-phosphooxyethyl)thiazole + ADP + H+ - thiamine salvage IV (yeast):
H2O + thiamine ⟶ 4-amino-2-methyl-5-pyrimidinemethanol + 5-(2-hydroxyethyl)-4-methylthiazole + H+ - thiamine salvage IV (yeast):
H2O + thiamine ⟶ 4-amino-2-methyl-5-pyrimidinemethanol + 5-(2-hydroxyethyl)-4-methylthiazole + H+ - thiamine salvage IV (yeast):
5-(2-hydroxyethyl)-4-methylthiazole + ATP ⟶ 4-methyl-5-(2-phosphooxyethyl)thiazole + ADP + H+ - hydroxymethylpyrimidine salvage:
4-amino-2-methyl-5-pyrimidinemethanol + ATP ⟶ ADP + H+ + HMP-P - thiamine salvage IV (yeast):
5-(2-hydroxyethyl)-4-methylthiazole + ATP ⟶ 4-methyl-5-(2-phosphooxyethyl)thiazole + ADP + H+ - thiamine salvage IV (yeast):
5-(2-hydroxyethyl)-4-methylthiazole + ATP ⟶ 4-methyl-5-(2-phosphooxyethyl)thiazole + ADP + H+ - thiamine salvage IV (yeast):
H2O + thiamine ⟶ 4-amino-2-methyl-5-pyrimidinemethanol + 5-(2-hydroxyethyl)-4-methylthiazole + H+ - hydroxymethylpyrimidine salvage:
4-amino-2-methyl-5-pyrimidinemethanol + ATP ⟶ ADP + H+ + HMP-P - thiamine salvage IV (yeast):
5-(2-hydroxyethyl)-4-methylthiazole + ATP ⟶ 4-methyl-5-(2-phosphooxyethyl)thiazole + ADP + H+ - hydroxymethylpyrimidine salvage:
4-amino-2-methyl-5-pyrimidinemethanol + ATP ⟶ ADP + H+ + HMP-P - thiamine salvage IV (yeast):
5-(2-hydroxyethyl)-4-methylthiazole + ATP ⟶ 4-methyl-5-(2-phosphooxyethyl)thiazole + ADP + H+ - thiamine salvage IV (yeast):
5-(2-hydroxyethyl)-4-methylthiazole + ATP ⟶ 4-methyl-5-(2-phosphooxyethyl)thiazole + ADP + H+ - hydroxymethylpyrimidine salvage:
4-amino-2-methyl-5-pyrimidinemethanol + ATP ⟶ ADP + H+ + HMP-P - thiamine salvage IV (yeast):
5-(2-hydroxyethyl)-4-methylthiazole + ATP ⟶ 4-methyl-5-(2-phosphooxyethyl)thiazole + ADP + H+ - thiamine salvage IV (yeast):
5-(2-hydroxyethyl)-4-methylthiazole + ATP ⟶ 4-methyl-5-(2-phosphooxyethyl)thiazole + ADP + H+ - thiamine salvage IV (yeast):
5-(2-hydroxyethyl)-4-methylthiazole + ATP ⟶ 4-methyl-5-(2-phosphooxyethyl)thiazole + ADP + H+ - hydroxymethylpyrimidine salvage:
4-amino-2-methyl-5-pyrimidinemethanol + ATP ⟶ ADP + H+ + HMP-P - thiamine salvage IV (yeast):
H2O + thiamine ⟶ 4-amino-2-methyl-5-pyrimidinemethanol + 5-(2-hydroxyethyl)-4-methylthiazole + H+ - thiamine salvage IV (yeast):
5-(2-hydroxyethyl)-4-methylthiazole + ATP ⟶ 4-methyl-5-(2-phosphooxyethyl)thiazole + ADP + H+ - thiamine salvage IV (yeast):
H2O + thiamine ⟶ 4-amino-2-methyl-5-pyrimidinemethanol + 5-(2-hydroxyethyl)-4-methylthiazole + H+ - thiamine salvage IV (yeast):
5-(2-hydroxyethyl)-4-methylthiazole + ATP ⟶ 4-methyl-5-(2-phosphooxyethyl)thiazole + ADP + H+ - thiamine salvage IV (yeast):
5-(2-hydroxyethyl)-4-methylthiazole + ATP ⟶ 4-methyl-5-(2-phosphooxyethyl)thiazole + ADP + H+ - thiamine salvage IV (yeast):
5-(2-hydroxyethyl)-4-methylthiazole + ATP ⟶ 4-methyl-5-(2-phosphooxyethyl)thiazole + ADP + H+ - hydroxymethylpyrimidine salvage:
4-amino-2-methyl-5-pyrimidinemethanol + ATP ⟶ ADP + H+ + HMP-P - thiamine salvage IV (yeast):
5-(2-hydroxyethyl)-4-methylthiazole + ATP ⟶ 4-methyl-5-(2-phosphooxyethyl)thiazole + ADP + H+ - thiamine salvage IV (yeast):
5-(2-hydroxyethyl)-4-methylthiazole + ATP ⟶ 4-methyl-5-(2-phosphooxyethyl)thiazole + ADP + H+ - hydroxymethylpyrimidine salvage:
4-amino-2-methyl-5-pyrimidinemethanol + ATP ⟶ ADP + H+ + HMP-P - thiamine salvage IV (yeast):
5-(2-hydroxyethyl)-4-methylthiazole + ATP ⟶ 4-methyl-5-(2-phosphooxyethyl)thiazole + ADP + H+ - thiamine salvage IV (yeast):
5-(2-hydroxyethyl)-4-methylthiazole + ATP ⟶ 4-methyl-5-(2-phosphooxyethyl)thiazole + ADP + H+ - thiamine salvage IV (yeast):
5-(2-hydroxyethyl)-4-methylthiazole + ATP ⟶ 4-methyl-5-(2-phosphooxyethyl)thiazole + ADP + H+ - thiamine salvage IV (yeast):
H2O + thiamine ⟶ 4-amino-2-methyl-5-pyrimidinemethanol + 5-(2-hydroxyethyl)-4-methylthiazole + H+ - hydroxymethylpyrimidine salvage:
4-amino-2-methyl-5-pyrimidinemethanol + ATP ⟶ ADP + H+ + HMP-P - thiamine salvage IV (yeast):
5-(2-hydroxyethyl)-4-methylthiazole + ATP ⟶ 4-methyl-5-(2-phosphooxyethyl)thiazole + ADP + H+ - thiamine salvage IV (yeast):
H2O + thiamine ⟶ 4-amino-2-methyl-5-pyrimidinemethanol + 5-(2-hydroxyethyl)-4-methylthiazole + H+ - hydroxymethylpyrimidine salvage:
4-amino-2-methyl-5-pyrimidinemethanol + ATP ⟶ ADP + H+ + HMP-P - thiamine salvage IV (yeast):
H2O + thiamine ⟶ 4-amino-2-methyl-5-pyrimidinemethanol + 5-(2-hydroxyethyl)-4-methylthiazole + H+ - thiamine salvage IV (yeast):
5-(2-hydroxyethyl)-4-methylthiazole + ATP ⟶ 4-methyl-5-(2-phosphooxyethyl)thiazole + ADP + H+ - hydroxymethylpyrimidine salvage:
4-amino-2-methyl-5-pyrimidinemethanol + ATP ⟶ ADP + H+ + HMP-P - thiamine salvage IV (yeast):
5-(2-hydroxyethyl)-4-methylthiazole + ATP ⟶ 4-methyl-5-(2-phosphooxyethyl)thiazole + ADP + H+ - thiamine salvage IV (yeast):
5-(2-hydroxyethyl)-4-methylthiazole + ATP ⟶ 4-methyl-5-(2-phosphooxyethyl)thiazole + ADP + H+ - thiamine salvage IV (yeast):
5-(2-hydroxyethyl)-4-methylthiazole + ATP ⟶ 4-methyl-5-(2-phosphooxyethyl)thiazole + ADP + H+ - thiamine salvage IV (yeast):
4-amino-2-methyl-5-pyrimidinemethanol + ATP ⟶ ADP + H+ + HMP-P - hydroxymethylpyrimidine salvage:
4-amino-2-methyl-5-pyrimidinemethanol + ATP ⟶ ADP + H+ + HMP-P - thiamine salvage IV (yeast):
H2O + thiamine ⟶ 4-amino-2-methyl-5-pyrimidinemethanol + 5-(2-hydroxyethyl)-4-methylthiazole + H+ - hydroxymethylpyrimidine salvage:
4-amino-2-methyl-5-pyrimidinemethanol + ATP ⟶ ADP + H+ + HMP-P - thiamine salvage IV (yeast):
5-(2-hydroxyethyl)-4-methylthiazole + ATP ⟶ 4-methyl-5-(2-phosphooxyethyl)thiazole + ADP + H+ - thiamine salvage IV (yeast):
5-(2-hydroxyethyl)-4-methylthiazole + ATP ⟶ 4-methyl-5-(2-phosphooxyethyl)thiazole + ADP + H+ - thiamine salvage IV (yeast):
5-(2-hydroxyethyl)-4-methylthiazole + ATP ⟶ 4-methyl-5-(2-phosphooxyethyl)thiazole + ADP + H+ - thiamine salvage IV (yeast):
H2O + thiamine ⟶ 4-amino-2-methyl-5-pyrimidinemethanol + 5-(2-hydroxyethyl)-4-methylthiazole + H+ - thiamine salvage IV (yeast):
H2O + thiamine ⟶ 4-amino-2-methyl-5-pyrimidinemethanol + 5-(2-hydroxyethyl)-4-methylthiazole + H+ - thiamine salvage IV (yeast):
H2O + thiamine ⟶ 4-amino-2-methyl-5-pyrimidinemethanol + 5-(2-hydroxyethyl)-4-methylthiazole + H+ - thiamine salvage IV (yeast):
5-(2-hydroxyethyl)-4-methylthiazole + ATP ⟶ 4-methyl-5-(2-phosphooxyethyl)thiazole + ADP + H+ - thiamine salvage IV (yeast):
H2O + thiamine ⟶ 4-amino-2-methyl-5-pyrimidinemethanol + 5-(2-hydroxyethyl)-4-methylthiazole + H+ - thiamine salvage IV (yeast):
H2O + thiamine ⟶ 4-amino-2-methyl-5-pyrimidinemethanol + 5-(2-hydroxyethyl)-4-methylthiazole + H+ - hydroxymethylpyrimidine salvage:
4-amino-2-methyl-5-pyrimidinemethanol + ATP ⟶ ADP + H+ + HMP-P - thiamine salvage IV (yeast):
5-(2-hydroxyethyl)-4-methylthiazole + ATP ⟶ 4-methyl-5-(2-phosphooxyethyl)thiazole + ADP + H+ - thiamine salvage IV (yeast):
5-(2-hydroxyethyl)-4-methylthiazole + ATP ⟶ 4-methyl-5-(2-phosphooxyethyl)thiazole + ADP + H+ - thiamine salvage IV (yeast):
H2O + thiamine ⟶ 4-amino-2-methyl-5-pyrimidinemethanol + 5-(2-hydroxyethyl)-4-methylthiazole + H+ - thiamine salvage IV (yeast):
H2O + thiamine ⟶ 4-amino-2-methyl-5-pyrimidinemethanol + 5-(2-hydroxyethyl)-4-methylthiazole + H+ - hydroxymethylpyrimidine salvage:
4-amino-2-methyl-5-pyrimidinemethanol + ATP ⟶ ADP + H+ + HMP-P - thiamine salvage IV (yeast):
5-(2-hydroxyethyl)-4-methylthiazole + ATP ⟶ 4-methyl-5-(2-phosphooxyethyl)thiazole + ADP + H+ - hydroxymethylpyrimidine salvage:
4-amino-2-methyl-5-pyrimidinemethanol + ATP ⟶ ADP + H+ + HMP-P - thiamine diphosphate salvage IV (yeast):
H2O + thiamine phosphate ⟶ phosphate + thiamine - hydroxymethylpyrimidine salvage:
4-amino-2-methyl-5-pyrimidinemethanol + ATP ⟶ ADP + H+ + HMP-P - thiamine diphosphate salvage IV (yeast):
H2O + thiamine phosphate ⟶ phosphate + thiamine
COVID-19 Disease Map(0)
PathBank(1)
- Vitamin B1/Thiamine Metabolism:
Adenosine triphosphate + Thiamine ⟶ Adenosine monophosphate + Hydrogen Ion + Thiamine pyrophosphate
PharmGKB(0)
5 个相关的物种来源信息
- 7461 - Apis cerana: 10.1371/JOURNAL.PONE.0175573
- 1423 - Bacillus subtilis: 10.1128/JB.186.5.1571-1573.2004
- 3039 - Euglena gracilis: 10.3389/FBIOE.2021.662655
- 9606 - Homo sapiens: -
- 29760 - Vitis vinifera: 10.1016/J.DIB.2020.106469
在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：
- PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
- NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
- Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
- Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。
点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。
文献列表
- Maria Rapala-Kozik, Natalia Wolak, Marta Kujda, Agnieszka K Banas. The upregulation of thiamine (vitamin B1) biosynthesis in Arabidopsis thaliana seedlings under salt and osmotic stress conditions is mediated by abscisic acid at the early stages of this stress response.
BMC plant biology.
2012 Jan; 12(?):2. doi:
10.1186/1471-2229-12-2. [PMID: 22214485] - Maria Rapala-Kozik, Mariusz Olczak, Katarzyna Ostrowska, Agata Starosta, Andrzej Kozik. Molecular characterization of the thi3 gene involved in thiamine biosynthesis in Zea mays: cDNA sequence and enzymatic and structural properties of the recombinant bifunctional protein with 4-amino-5-hydroxymethyl-2-methylpyrimidine (phosphate) kinase and thiamine monophosphate synthase activities.
The Biochemical journal.
2007 Dec; 408(2):149-59. doi:
10.1042/bj20070677. [PMID: 17696876] - R Karunakaran, K Ebert, S Harvey, M E Leonard, V Ramachandran, P S Poole. Thiamine is synthesized by a salvage pathway in Rhizobium leguminosarum bv. viciae strain 3841.
Journal of bacteriology.
2006 Sep; 188(18):6661-8. doi:
10.1128/jb.00641-06. [PMID: 16952958]