Citreoviridin (BioDeep_00000409406)

natural product

代谢物信息卡片

(-)-Citreoviridin

化学式: C23H30O6 (402.2042)
中文名称: 黄绿青霉素
谱图信息: 最多检出来源 Polyporus(natural_products) 10.98%

分子结构信息

SMILES: CC1C(C(C(O1)(C)C=C(C)C=CC=CC=CC2=C(C(=CC(=O)O2)OC)C)O)(C)O
InChI: InChI=1S/C23H30O6/c1-15(14-22(4)21(25)23(5,26)17(3)29-22)11-9-7-8-10-12-18-16(2)19(27-6)13-20(24)28-18/h7-14,17,21,25-26H,1-6H3/b8-7+,11-9+,12-10+,15-14+/t17-,21+,22+,23+/m1/s1

描述信息

D019995 - Laboratory Chemicals > D007202 - Indicators and Reagents > D001313 - Aurovertins

同义名列表

18 个代谢物同义名

(-)-Citreoviridin; Citreoviridin; Citreoviridin; 2H-Pyran-2-one, 4-methoxy-5-methyl-6-(7-methyl-8-(tetrahydro-3,4-dihydroxy-2,4,5-trimethyl-2-furanyl)-1,3,5,7-octatetraenyl)-; 2H-Pyran-2-one, 4-methoxy-5-methyl-6-(7-methyl-8-(tetrahydro-3,4-dihydroxy-2,4,5-trimethyl-2-furanyl)-1,3,5,7-octatetraenyl)-, (2R-(2alpha(1E,3E,5E,7E),3beta,4alpha,5alpha))-; 2H-Pyran-2-one, 4-methoxy-5-methyl-6-(7-methyl-8-(tetrahydro-3,4-dihydroxy-2,4,5-trimethyl-2-furyl)-1,3,5,7-octatetraenyl)-; 2H-Pyran-2-one, 4-methoxy-5-methyl-6-[7-methyl-8-(tetrahydro-3,4-dihydroxy-2,4,5-trimethyl-2-furanyl)-1,3,5,7-octatetraenyl]-; 2H-Pyran-2-one, 4-methoxy-5-methyl-6-[7-methyl-8-(tetrahydro-3,4-dihydroxy-2,4,5-trimethyl-2-furanyl)-1,3,5,7-octatetraenyl]-, [2R-[2.alpha.(1E,3E,5E,7E),3.beta.,4.alpha.,5.alpha.]]-; 2H-Pyran-2-one, 4-methoxy-5-methyl-6-[7-methyl-8-(tetrahydro-3,4-dihydroxy-2,4,5-trimethyl-2-furyl)-1,3,5,7-octatetraenyl]-; 4-Methoxy-5-methyl-6-(7-methyl-8-(tetrahydro-3,4-dihydroxy-2,4,5-trimethyl-2-furyl)-1,3,5,7-octatetraenyl)-2H-pyran-2-one; 6-((1E,3E,5E,7E)-8-((2S,3R,4R,5R)-3,4-dihydroxy-2,4,5-trimethyloxolan-2-yl)-7-methylocta-1,3,5,7-tetraenyl)-4-methoxy-5-methylpyran-2-one; 6-[(1E,3E,5E,7E)-8-[(2S,3R,4R,5R)-3,4-dihydroxy-2,4,5-trimethyloxolan-2-yl]-7-methylocta-1,3,5,7-tetraenyl]-4-methoxy-5-methylpyran-2-one; Citreoviridin (80%, Contain Isocitreoviridin); Citreoviridin A; Citreoviridine; Citreoviridine A; OWX7Q6CF4F; UNII-OWX7Q6CF4F

数据库引用编号

12 个数据库交叉引用编号

ChEBI: CHEBI:80713
KEGG: C16766
PubChem: 6436023
ChEMBL: CHEMBL4456411
CAS: 25425-12-1
MoNA: CCMSLIB00005435760
PubChem: 96023290
NIKKAJI: J17.163H
KNApSAcK: 80713
LOTUS: LTS0150527
MeSH: citreoviridin
Wikipedia: Citreoviridin

分类词条

Linear polyenes

代谢反应

0 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

17 个相关的物种来源信息

4890 - Ascomycota: LTS0150527
1131492 - Aspergillaceae: LTS0150527
5052 - Aspergillus: LTS0150527
41288 - Aspergillus aureoterreus: 10.1021/ACS.ORGLETT.6B00299
41288 - Aspergillus aureoterreus: LTS0150527
33178 - Aspergillus terreus: LTS0150527
2759 - Eukaryota: LTS0150527
147545 - Eurotiomycetes: LTS0150527
4751 - Fungi: LTS0150527
5073 - Penicillium: LTS0150527
36645 - Penicillium miczynskii: 10.1016/S0040-4039(00)97883-3
36645 - Penicillium miczynskii: 10.1246/CL.1997.33
36645 - Penicillium miczynskii: LTS0150527
1343405 - Penicillium pedemontanum: 10.1016/S0040-4039(00)97883-3
1343405 - Penicillium pedemontanum: 10.1246/CL.1997.33
1343405 - Penicillium pedemontanum: LTS0150527
28568 - Trichocomaceae: LTS0150527

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：

PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。

亚细胞结构定位		关联基因列表

文献列表

Mizuki Sekiya, Yu Shimoyama, Taichi Ishikawa, Minoru Sasaki, Masamitsu Futai, Mayumi Nakanishi-Matsui. Porphyromonas gingivalis is highly sensitive to inhibitors of a proton-pumping ATPase. Biochemical and biophysical research communications. 2018 04; 498(4):837-841. doi: 10.1016/j.bbrc.2018.03.066. [PMID: 29530525]
Chang Feng, Dandan Li, Liping Jiang, Xiaofang Liu, Qiujuan Li, Chengyan Geng, Xiance Sun, Guang Yang, Xiaofeng Yao, Min Chen. Citreoviridin induces triglyceride accumulation in hepatocytes through inhibiting PPAR-α in vivo and in vitro. Chemico-biological interactions. 2017 Aug; 273(?):212-218. doi: 10.1016/j.cbi.2017.06.021. [PMID: 28645467]
Haifeng Hou, Xiaolan Qu, Yuqin Li, Yueyue Kong, Baoxiu Jia, Xiaojun Yao, Baofa Jiang. Binding of citreoviridin to human serum albumin: multispectroscopic and molecular docking. BioMed research international. 2015; 2015(?):162391. doi: 10.1155/2015/162391. [PMID: 25977915]
Hai-Feng Hou, Na Yuan, Qing Guo, Tao Sun, Cheng Li, Jian-Bao Liu, Qun-Wei Li, Bao-Fa Jiang. Citreoviridin Enhances Atherogenesis in Hypercholesterolemic ApoE-Deficient Mice via Upregulating Inflammation and Endothelial Dysfunction. PloS one. 2015; 10(5):e0125956. doi: 10.1371/journal.pone.0125956. [PMID: 25933220]
Teigo Asai, Dan Luo, Kouwa Yamashita, Yoshiteru Oshima. Structures and biomimetic synthesis of novel α-pyrone polyketides of an endophytic Penicillium sp. in Catharanthus roseus. Organic letters. 2013 Mar; 15(5):1020-3. doi: 10.1021/ol303506t. [PMID: 23405967]
Yi-Hsuan Wu, Chia-Wei Hu, Chih-Wei Chien, Yu-Ju Chen, Hsuan-Cheng Huang, Hsueh-Fen Juan. Quantitative proteomic analysis of human lung tumor xenografts treated with the ectopic ATP synthase inhibitor citreoviridin. PloS one. 2013; 8(8):e70642. doi: 10.1371/journal.pone.0070642. [PMID: 23990911]
K Nishie, R J Cole, J W Dorner. Toxicity of citreoviridin. Research communications in chemical pathology and pharmacology. 1988 Jan; 59(1):31-52. doi: NULL. [PMID: 3258434]
R W Campbell, S C Achuff, A Pottage, A Murray, L F Prescott, D G Julian. Mexiletine in the prophylaxis of ventricular arrhythmias during acute myocardial infarction. Journal of cardiovascular pharmacology. 1979 Jan; 1(1):43-52. doi: 10.1097/00005344-197901000-00005. [PMID: 94381]