Lysicamine (BioDeep_00000395573)

 

Secondary id: BioDeep_00000331237

PANOMIX_OTCML-2023 natural product


代谢物信息卡片


15,16-dimethoxy-10-azatetracyclo[7.7.1.0?,?.0??,??]heptadeca-1(16),2,4,6,9(17),10,12,14-octaen-8-one

化学式: C18H13NO3 (291.0895388)
中文名称:
谱图信息: 最多检出来源 Chinese Herbal Medicine(otcml) 5.32%

分子结构信息

SMILES: COC1=C(C2=C3C(=C1)C=CN=C3C(=O)C4=CC=CC=C42)OC
InChI: InChI=1S/C18H13NO3/c1-21-13-9-10-7-8-19-16-14(10)15(18(13)22-2)11-5-3-4-6-12(11)17(16)20/h3-9H,1-2H3

描述信息

Lysicamine is an alkaloid antibiotic and an oxoaporphine alkaloid. It has a role as a metabolite.
Lysicamine is a natural product found in Annona purpurea, Annona papilionella, and other organisms with data available.
A natural product found in Annona glabra.

同义名列表

15 个代谢物同义名

15,16-dimethoxy-10-azatetracyclo[7.7.1.0?,?.0??,??]heptadeca-1(16),2,4,6,9(17),10,12,14-octaen-8-one; 15,16-dimethoxy-10-azatetracyclo[7.7.1.02,7.013,17]heptadeca-1(17),2,4,6,9,11,13,15-octaen-8-one; Noraporphin-7-one, 4,5,6,6a-tetradehydro-1,2-dimethoxy-; 7H-Dibenzo(de,g)quinolin-7-one, 1,2-dimethoxy- (9CI); 1,2-Dimethoxy-7H-dibenzo[de,g]quinolin-7-one #; 7H-Dibenzo[de,g]quinolin-7-one, 1,2-dimethoxy-; 7H-Dibenzo(de,g)quinolin-7-one, 1,2-dimethoxy-; 5-21-13-00382 (Beilstein Handbook Reference); 1,2-dimethoxy-7H-dibenzo(de,g)quinolin-7-one; (+)-ushinsunine-beta-N-oxide; DPBMWJXWUINLQT-UHFFFAOYSA-N; UNII-6L30DD6R7O; oxonuciferine; 6L30DD6R7O; Lysicamine



数据库引用编号

9 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(0)

BioCyc(0)

PlantCyc(0)

代谢反应

0 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

153 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：

  • PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。



文献列表

  • André Campos Machado, Tamiris Reissa Cipriano da Silva, Cristiano Raminelli, Luciano Caseli. The composition of fusogenic lipid mixtures at the air-water modulates the physicochemical properties changes upon interaction with lysicamine. Biophysical chemistry. 2023 02; 293(?):106947. doi: 10.1016/j.bpc.2022.106947. [PMID: 36566720]
  • André Campos Machado, Tamiris Reissa Cipriano da Silva, Cristiano Raminelli, Luciano Caseli. Unsaturation pattern of phosphatidylglycerols modulating the interaction of lysicamine with cells membrane models at the air-water interface. Colloids and surfaces. B, Biointerfaces. 2023 Feb; 222(?):113045. doi: 10.1016/j.colsurfb.2022.113045. [PMID: 36446237]
  • InWha Park, Hee Sun Byun, Gang Min Hur, MinKyun Na. Tulipiferamide A, an Alkamide from Liriodendron tulipifera, Exhibits an Anti-Inflammatory Effect via Targeting IKKβ Phosphorylation. Journal of natural products. 2021 05; 84(5):1598-1606. doi: 10.1021/acs.jnatprod.1c00146. [PMID: 33939429]
  • Taghreed A Majrashi, Fazila Zulfiqar, Amar G Chittiboyina, Zulfiqar Ali, Ikhlas A Khan. Isoquinoline alkaloids from Asimina triloba. Natural product research. 2019 Oct; 33(19):2823-2829. doi: 10.1080/14786419.2018.1504045. [PMID: 30453785]
  • Kok Kwan Tan, Teng Jing Khoo, Mogana Rajagopal, Christophe Wiart. Antibacterial alkaloids from Artabotrys crassifolius Hook.f. & Thomson. Natural product research. 2015; 29(24):2346-9. doi: 10.1080/14786419.2015.1013954. [PMID: 25738993]
  • Ya-Fei Kang, Chi-Ming Liu, Chiu-Li Kao, Chung-Yi Chen. Antioxidant and anticancer constituents from the leaves of Liriodendron tulipifera. Molecules (Basel, Switzerland). 2014 Apr; 19(4):4234-45. doi: 10.3390/molecules19044234. [PMID: 24705566]
  • Felipe M A da Silva, Afonso D L de Souza, Hector H F Koolen, Andersson Barison, Mayara E Vendramin, Emmanoel V Costa, Antonio G Ferreira, Maria Lúcia B Pinheiro. Phytochemical study of the alkaloidal fractions of Unonopsis duckei R. E. Fr. guided by electrospray ionisation ion-trap tandem mass spectrometry. Phytochemical analysis : PCA. 2014 Jan; 25(1):45-9. doi: 10.1002/pca.2458. [PMID: 23922254]
  • Seikou Nakamura, Souichi Nakashima, Genzo Tanabe, Yoshimi Oda, Nami Yokota, Katsuyoshi Fujimoto, Takahiro Matsumoto, Rika Sakuma, Tomoe Ohta, Keiko Ogawa, Shino Nishida, Hisako Miki, Hisashi Matsuda, Osamu Muraoka, Masayuki Yoshikawa. Alkaloid constituents from flower buds and leaves of sacred lotus (Nelumbo nucifera, Nymphaeaceae) with melanogenesis inhibitory activity in B16 melanoma cells. Bioorganic & medicinal chemistry. 2013 Feb; 21(3):779-87. doi: 10.1016/j.bmc.2012.11.038. [PMID: 23270663]
  • Emmanoel Vilaça Costa, Maria Lúcia B Pinheiro, Andersson Barison, Francinete R Campos, Marcos J Salvador, Beatriz Helena L N S Maia, Elaine C Cabral, Marcos N Eberlin. Alkaloids from the bark of Guatteria hispida and their evaluation as antioxidant and antimicrobial agents. Journal of natural products. 2010 Jun; 73(6):1180-3. doi: 10.1021/np100013r. [PMID: 20476748]
  • Hui-Min Wang, Wen-Li Lo, Lee-Yu Huang, Yau-Der Wang, Chung-Yi Chen. Chemical constituents from the leaves of Michelia alba. Natural product research. 2010 Mar; 24(5):398-406. doi: 10.1080/14786410802394132. [PMID: 20306361]
  • Zhizhen Zhang, Hala N ElSohly, Melissa R Jacob, David S Pasco, Larry A Walker, Alice M Clark. New sesquiterpenoids from the root of Guatteria multivenia. Journal of natural products. 2002 Jun; 65(6):856-9. doi: 10.1021/np0200717. [PMID: 12088427]
  • G G Harrigan, A A Gunatilaka, D G Kingston, G W Chan, R K Johnson. Isolation of bioactive and other oxoaporphine alkaloids from two annonaceous plants, Xylopia aethiopica and Miliusa cf. banacea. Journal of natural products. 1994 Jan; 57(1):68-73. doi: 10.1021/np50103a009. [PMID: 8158166]