(-)-Isopulegol (BioDeep_00000034998)

   

human metabolite Endogenous natural product


代谢物信息卡片


(1R,2S,5R)-5-methyl-2-(prop-1-en-2-yl)cyclohexan-1-ol

化学式: C10H18O (154.1357578)
中文名称: (-)-异蒲勒醇
谱图信息: 最多检出来源 () 0%

分子结构信息

SMILES: C=C(C)[C@@H]1CC[C@@H](C)C[C@H]1O
InChI: InChI=1S/C10H18O/c1-7(2)9-5-4-8(3)6-10(9)11/h8-11H,1,4-6H2,2-3H3/t8-,9+,10-/m1/s1

描述信息

Isolated from Mentha pulegium (European pennyroyal) and other essential oils. (-)-Isopulegol is found in many foods, some of which are lemon balm, lemon grass, rosemary, and fats and oils.
(-)-Isopulegol is found in cornmint. (-)-Isopulegol is isolated from Mentha pulegium (European pennyroyal) and other essential oil

同义名列表

7 个代谢物同义名

(1R,2S,5R)-5-methyl-2-(prop-1-en-2-yl)cyclohexan-1-ol; 5-Methyl-2-(1-methylethenyl)-(1R,2S,5R)-cyclohexanol; (1R,3R,4S)-(-)-P-Menth-8-en-3-ol; (-)-L-Isopulegol; (-)-Isopulegol; L-Isopulegol; Isopulegol



数据库引用编号

11 个数据库交叉引用编号

分类词条

相关代谢途径

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代谢反应

0 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(0)

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Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

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PharmGKB(0)

44 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：

  • PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

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文献列表

  • Karunanithi Kalaivani, Chandrasekaran Sankaranarayanan. Modulatory effect of isopulegol on hepatic key enzymes of glucose metabolism in high-fat diet/streptozotocin-induced diabetic rats. Archives of physiology and biochemistry. 2021 Aug; 127(4):318-326. doi: 10.1080/13813455.2019.1638415. [PMID: 31291130]
  • Irina V Ilyina, Oksana S Patrusheva, Vladimir V Zarubaev, Maria A Misiurina, Alexander V Slita, Iana L Esaulkova, Dina V Korchagina, Yuri V Gatilov, Sophia S Borisevich, Konstantin P Volcho, Nariman F Salakhutdinov. Influenza antiviral activity of F- and OH-containing isopulegol-derived octahydro-2H-chromenes. Bioorganic & medicinal chemistry letters. 2021 01; 31(?):127677. doi: 10.1016/j.bmcl.2020.127677. [PMID: 33171219]
  • Chandrasekaran Sankaranarayanan, Karunanithi Kalaivani. Isopulegol Mitigates Hyperglycemia Mediated Oxidative and Endoplasmic Reticulum Stress in HFD/STZ Induced Diabetic Rats. Archives of medical research. 2020 04; 51(3):204-214. doi: 10.1016/j.arcmed.2020.02.001. [PMID: 32111490]
  • Xiaochang Liu, Meiying Liu, Chao Liu, Peng Quan, Yongshan Zhao, Liang Fang. An insight into the molecular mechanism of the temporary enhancement effect of isopulegol decanoate on the skin. International journal of pharmaceutics. 2017 Aug; 529(1-2):161-167. doi: 10.1016/j.ijpharm.2017.06.023. [PMID: 28610893]
  • H Tolba, H Moghrani, A Benelmouffok, D Kellou, R Maachi. Essential oil of Algerian Eucalyptus citriodora: Chemical composition, antifungal activity. Journal de mycologie medicale. 2015 Dec; 25(4):e128-33. doi: 10.1016/j.mycmed.2015.10.009. [PMID: 26597375]
  • René F Ramos Alvarenga, Baojie Wan, Taichi Inui, Scott G Franzblau, Guido F Pauli, Birgit U Jaki. Airborne antituberculosis activity of Eucalyptus citriodora essential oil. Journal of natural products. 2014 Mar; 77(3):603-10. doi: 10.1021/np400872m. [PMID: 24641242]
  • Jun Han, Soon-Il Kim, Byeoung-Ryeol Choi, Sang-Guei Lee, Young-Joon Ahn. Fumigant toxicity of lemon eucalyptus oil constituents to acaricide-susceptible and acaricide-resistant Tetranychus urticae. Pest management science. 2011 Dec; 67(12):1583-8. doi: 10.1002/ps.2216. [PMID: 21674753]
  • Maria Izabel Gomes Silva, Maria Angélica Gomes Silva, Manuel Rufino de Aquino Neto, Brinell Arcanjo Moura, Helenira Lourenço de Sousa, Everton Paulo Homem de Lavor, Patrícia Freire de Vasconcelos, Danielle Silveira Macêdo, Damião Pergentino de Sousa, Silvânia Maria Mendes Vasconcelos, Francisca Cléa Florenço de Sousa. Effects of isopulegol on pentylenetetrazol-induced convulsions in mice: possible involvement of GABAergic system and antioxidant activity. Fitoterapia. 2009 Dec; 80(8):506-13. doi: 10.1016/j.fitote.2009.06.011. [PMID: 19559770]
  • H M Ferraz, M V Grazini, C M Ribeiro, U Brocksom, T J Brocksom. A short route to (-)-mintlactone by thallium(III)-mediated cyclization of (-)-isopulegol. The Journal of organic chemistry. 2000 Apr; 65(8):2606-7. doi: 10.1021/jo991802j. [PMID: 10789485]