Muscimol (BioDeep_00000003468)
Secondary id: BioDeep_00001867707
human metabolite blood metabolite
代谢物信息卡片
5-(Aminomethyl)-3(2H)-isoxazolone
化学式: C4H6N2O2 (114.04292559999999)
中文名称: 蝇蕈醇
谱图信息:
最多检出来源 Homo sapiens(blood) 66.67%
分子结构信息
SMILES: C1=C(ONC1=O)CN
InChI: InChI=1S/C4H6N2O2/c5-2-3-1-4(7)6-8-3/h1H,2,5H2,(H,6,7)
描述信息
D018377 - Neurotransmitter Agents > D018682 - GABA Agents > D018755 - GABA Agonists
D009676 - Noxae > D011042 - Poisons > D009183 - Mycotoxins
KEIO_ID M115
同义名列表
数据库引用编号
21 个数据库交叉引用编号
- ChEBI: CHEBI:7035
- KEGG: C08311
- PubChem: 4266
- HMDB: HMDB0254955
- Metlin: METLIN64833
- DrugBank: DB12458
- ChEMBL: CHEMBL273481
- Wikipedia: Muscimol
- MeSH: Muscimol
- KNApSAcK: C00001423
- chemspider: 4116
- CAS: 2763-96-4
- MoNA: KO003527
- MoNA: KO003528
- MoNA: KO003531
- MoNA: KO003529
- MoNA: KO003530
- PMhub: MS000009722
- PubChem: 10509
- NIKKAJI: J7.909J
- RefMet: Muscimol
分类词条
相关代谢途径
Reactome(0)
BioCyc(0)
PlantCyc(0)
代谢反应
0 个相关的代谢反应过程信息。
Reactome(0)
BioCyc(0)
WikiPathways(0)
Plant Reactome(0)
INOH(0)
PlantCyc(0)
COVID-19 Disease Map(0)
PathBank(0)
PharmGKB(0)
1 个相关的物种来源信息
在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：
- PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
- NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
- Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
- Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。
点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。
文献列表
- Alexander Dushkov, Zuzana Vosáhlová, Alexander Tzintzarov, Květa Kalíková, Tomáš Křížek, Iva Ugrinova. Analysis of the Ibotenic Acid, Muscimol, and Ergosterol Content of an Amanita Muscaria Hydroalcoholic Extract with an Evaluation of Its Cytotoxic Effect against a Panel of Lung Cell Lines In Vitro.
Molecules (Basel, Switzerland).
2023 Sep; 28(19):. doi:
10.3390/molecules28196824. [PMID: 37836667] - Yu-Ting Su, Jie Liu, Dan-Ni Yang, Qing Cai, Zhu L Yang, Zuo-Hong Chen. Determination of ibotenic acid and muscimol in species of the genus Amanita section Amanita from China.
Toxicon : official journal of the International Society on Toxinology.
2023 Aug; ?(?):107257. doi:
10.1016/j.toxicon.2023.107257. [PMID: 37611670] - Ya-Hui Li, Dur-Zong Hsu, Chuan-Teng Liu, Victor Raj Mohan Chandrasekaran, Ming-Yie Liu. The protective effect of muscimol against systemic inflammatory response in endotoxemic mice is independent of GABAergic and cholinergic receptors.
Canadian journal of physiology and pharmacology.
2022 Jul; 100(7):665-678. doi:
10.1139/cjpp-2021-0682. [PMID: 35856422] - Laura C Ornelas, Kalynn Van Voorhies, Joyce Besheer. The role of the nucleus reuniens in regulating contextual conditioning with the predator odor TMT in female rats.
Psychopharmacology.
2021 Dec; 238(12):3411-3421. doi:
10.1007/s00213-021-05957-x. [PMID: 34390359] - Zhimin Song, Sujith Swarna, Joseph R Manns. Prioritization of social information by the basolateral amygdala in rats.
Neurobiology of learning and memory.
2021 10; 184(?):107489. doi:
10.1016/j.nlm.2021.107489. [PMID: 34271138] - Mark J Henderson, Kathleen A Trychta, Shyh-Ming Yang, Susanne Bäck, Adam Yasgar, Emily S Wires, Carina Danchik, Xiaokang Yan, Hideaki Yano, Lei Shi, Kuo-Jen Wu, Amy Q Wang, Dingyin Tao, Gergely Zahoránszky-Kőhalmi, Xin Hu, Xin Xu, David Maloney, Alexey V Zakharov, Ganesha Rai, Fumihiko Urano, Mikko Airavaara, Oksana Gavrilova, Ajit Jadhav, Yun Wang, Anton Simeonov, Brandon K Harvey. A target-agnostic screen identifies approved drugs to stabilize the endoplasmic reticulum-resident proteome.
Cell reports.
2021 04; 35(4):109040. doi:
10.1016/j.celrep.2021.109040. [PMID: 33910017] - Xiao-Min Xu, Jing-Shun Zhang, Bai-Fen Huang, Jian-Long Han, Qing Chen. Determination of ibotenic acid and muscimol in plasma by liquid chromatography-triple quadrupole mass spectrometry with bimolecular dansylation.
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences.
2020 Jun; 1146(?):122128. doi:
10.1016/j.jchromb.2020.122128. [PMID: 32361630] - Anna Poliwoda, Katarzyna Zielińska, Piotr P Wieczorek. Direct Analysis of Psilocin and Muscimol in Urine Samples Using Single Drop Microextraction Technique In-Line with Capillary Electrophoresis.
Molecules (Basel, Switzerland).
2020 Mar; 25(7):. doi:
10.3390/molecules25071566. [PMID: 32235328] - Cheryl A Frye, Vincent F Lembo, Alicia A Walf. Progesterone's Effects on Cognitive Performance of Male Mice Are Independent of Progestin Receptors but Relate to Increases in GABAA Activity in the Hippocampus and Cortex.
Frontiers in endocrinology.
2020; 11(?):552805. doi:
10.3389/fendo.2020.552805. [PMID: 33505354] - Yu Long, Stephen D Tyerman, Matthew Gilliham. Cytosolic GABA inhibits anion transport by wheat ALMT1.
The New phytologist.
2020 01; 225(2):671-678. doi:
10.1111/nph.16238. [PMID: 31591723] - Magdalena Olga Ciechanowska, Magdalena Łapot, Marek Kowalczyk, Tadeusz Malewski, Marek Brytan, Bożena Antkowiak, Franciszek Przekop. Does kisspeptin participate in GABA-mediated modulation of GnRH and GnRH receptor biosynthesis in the hypothalamic-pituitary unit of follicular-phase ewes?.
Pharmacological reports : PR.
2019 Aug; 71(4):636-643. doi:
10.1016/j.pharep.2019.02.019. [PMID: 31176893] - Megan C Romano, Hung K Doan, Robert H Poppenga, Michael S Filigenzi, Uneeda K Bryant, Cynthia L Gaskill. Fatal Amanita muscaria poisoning in a dog confirmed by PCR identification of mushrooms.
Journal of veterinary diagnostic investigation : official publication of the American Association of Veterinary Laboratory Diagnosticians, Inc.
2019 May; 31(3):485-487. doi:
10.1177/1040638719842897. [PMID: 30957709] - Michael J Moss, Robert G Hendrickson. Toxicity of muscimol and ibotenic acid containing mushrooms reported to a regional poison control center from 2002-2016.
Clinical toxicology (Philadelphia, Pa.).
2019 02; 57(2):99-103. doi:
10.1080/15563650.2018.1497169. [PMID: 30073844] - Midiã D J Seno, Danielle V Assis, Flávia Gouveia, Geiza F Antunes, Mayra Kuroki, Caroline C Oliveira, Lennon C T Santos, Rosana L Pagano, Raquel C R Martinez. The critical role of amygdala subnuclei in nociceptive and depressive-like behaviors in peripheral neuropathy.
Scientific reports.
2018 09; 8(1):13608. doi:
10.1038/s41598-018-31962-w. [PMID: 30206257] - Amy A Arguello, Rong Wang, Carey M Lyons, Jessica A Higginbotham, Matthew A Hodges, Rita A Fuchs. Role of the agranular insular cortex in contextual control over cocaine-seeking behavior in rats.
Psychopharmacology.
2017 Aug; 234(16):2431-2441. doi:
10.1007/s00213-017-4632-7. [PMID: 28462472] - Yonggang Gao, Jing-Jing Zhou, Yun Zhu, Therese Kosten, De-Pei Li. Chronic Unpredictable Mild Stress Induces Loss of GABA Inhibition in Corticotrophin-Releasing Hormone-Expressing Neurons through NKCC1 Upregulation.
Neuroendocrinology.
2017; 104(2):194-208. doi:
10.1159/000446114. [PMID: 27077366] - Somandla Ncube, Anna Poliwoda, Hlanganani Tutu, Piotr Wieczorek, Luke Chimuka. Multivariate optimization of the hollow fibre liquid phase microextraction of muscimol in human urine samples.
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences.
2016 Oct; 1033-1034(?):372-381. doi:
10.1016/j.jchromb.2016.09.008. [PMID: 27631575] - Giacomo Ronzoni, Maria Antón, Francisco Mora, Gregorio Segovia, Alberto Del Arco. Infralimbic cortex controls the activity of the hypothalamus-pituitary-adrenal axis and the formation of aversive memory: Effects of environmental enrichment.
Behavioural brain research.
2016 Jan; 297(?):338-44. doi:
10.1016/j.bbr.2015.10.037. [PMID: 26518332] - Rishabh Charan Choudhary, Ravindra Kumar Sharma, Kavita Gulati, Krishnan Ravi. Role of the paraventricular nucleus in the reflex diuresis to pulmonary lymphatic obstruction in rabbits.
Canadian journal of physiology and pharmacology.
2016 Jan; 94(1):18-27. doi:
10.1139/cjpp-2015-0109. [PMID: 26497164] - Zhigang Shi, Priscila A Cassaglia, Laura C Gotthardt, Virginia L Brooks. Hypothalamic Paraventricular and Arcuate Nuclei Contribute to Elevated Sympathetic Nerve Activity in Pregnant Rats: Roles of Neuropeptide Y and α-Melanocyte-Stimulating Hormone.
Hypertension (Dallas, Tex. : 1979).
2015 Dec; 66(6):1191-8. doi:
10.1161/hypertensionaha.115.06045. [PMID: 26483343] - Jie Liu, Dongping Huang, Jing Xu, Jiabin Tong, Zishan Wang, Li Huang, Yufang Yang, Xiaochen Bai, Pan Wang, Haiyun Suo, Yuanyuan Ma, Mei Yu, Jian Fei, Fang Huang. Tiagabine Protects Dopaminergic Neurons against Neurotoxins by Inhibiting Microglial Activation.
Scientific reports.
2015 Oct; 5(?):15720. doi:
10.1038/srep15720. [PMID: 26499517] - Sunita A Ramesh, Stephen D Tyerman, Bo Xu, Jayakumar Bose, Satwinder Kaur, Vanessa Conn, Patricia Domingos, Sana Ullah, Stefanie Wege, Sergey Shabala, José A Feijó, Peter R Ryan, Matthew Gilliham. GABA signalling modulates plant growth by directly regulating the activity of plant-specific anion transporters.
Nature communications.
2015 Jul; 6(?):7879. doi:
10.1038/ncomms8879. [PMID: 26219411] - Ken'ichi Yamaguchi. Evaluation for roles of neurosteroids in modulating forebrain mechanisms controlling vasopressin secretion and related phenomena in conscious rats.
Neuroscience research.
2015 Jun; 95(?):38-50. doi:
10.1016/j.neures.2015.01.002. [PMID: 25598212] - Feixue Liang, Xiaorui R Xiong, Brian Zingg, Xu-ying Ji, Li I Zhang, Huizhong W Tao. Sensory Cortical Control of a Visually Induced Arrest Behavior via Corticotectal Projections.
Neuron.
2015 May; 86(3):755-67. doi:
10.1016/j.neuron.2015.03.048. [PMID: 25913860] - Isabel Sollozo-Dupont, Erika Estrada-Camarena, Miguel Carro-Juárez, Carolina López-Rubalcava. GABAA/benzodiazepine receptor complex mediates the anxiolytic-like effect of Montanoa tomentosa.
Journal of ethnopharmacology.
2015 Mar; 162(?):278-86. doi:
10.1016/j.jep.2014.12.070. [PMID: 25582489] - K E A Wernecke, D Vincenz, S Storsberg, W D'Hanis, J Goldschmidt, M Fendt. Fox urine exposure induces avoidance behavior in rats and activates the amygdalar olfactory cortex.
Behavioural brain research.
2015 Feb; 279(?):76-81. doi:
10.1016/j.bbr.2014.11.020. [PMID: 25449843] - Megan E Bardgett, Amanda L Sharpe, Glenn M Toney. Activation of corticotropin-releasing factor receptors in the rostral ventrolateral medulla is required for glucose-induced sympathoexcitation.
American journal of physiology. Endocrinology and metabolism.
2014 Nov; 307(10):E944-53. doi:
10.1152/ajpendo.00291.2014. [PMID: 25269482] - S Deja, E Jawień, I Jasicka-Misiak, M Halama, P Wieczorek, P Kafarski, P Młynarz. Rapid determination of ibotenic acid and muscimol in human urine.
Magnetic resonance in chemistry : MRC.
2014 Nov; 52(11):711-4. doi:
10.1002/mrc.4104. [PMID: 25042675] - Pavlína Ginterová, Barbora Sokolová, Peter Ondra, Joanna Znaleziona, Jan Petr, Juraj Ševčík, Vítězslav Maier. Determination of mushroom toxins ibotenic acid, muscimol and muscarine by capillary electrophoresis coupled with electrospray tandem mass spectrometry.
Talanta.
2014 Jul; 125(?):242-7. doi:
10.1016/j.talanta.2014.03.019. [PMID: 24840440] - Juan Gabriel Tejas-Juárez, Ana María Cruz-Martínez, Verónica Elsa López-Alonso, Brenda García-Iglesias, Juan Manuel Mancilla-Díaz, Benjamín Florán-Garduño, Rodrigo Erick Escartín-Pérez. Stimulation of dopamine D4 receptors in the paraventricular nucleus of the hypothalamus of male rats induces hyperphagia: involvement of glutamate.
Physiology & behavior.
2014 Jun; 133(?):272-81. doi:
10.1016/j.physbeh.2014.04.040. [PMID: 24805978] - Robert Frithiof, Tao Xing, Michael J McKinley, Clive N May, Rohit Ramchandra. Intracarotid hypertonic sodium chloride differentially modulates sympathetic nerve activity to the heart and kidney.
American journal of physiology. Regulatory, integrative and comparative physiology.
2014 Apr; 306(8):R567-75. doi:
10.1152/ajpregu.00460.2013. [PMID: 24523342] - Ludmila de Lima Silveira, Elaine Fernanda da Silva, Aline Mourão de Andrade, Carlos Henrique Xavier, André Henrique Freiria-Oliveira, Diego Basile Colugnati, Carlos Henrique de Castro, Eduardo Colombari, Gustavo Rodrigues Pedrino. Involvement of the median preoptic nucleus in blood pressure control.
Neuroscience letters.
2014 Jan; 558(?):91-6. doi:
10.1016/j.neulet.2013.11.001. [PMID: 24269979] - Dmitry V Zaretsky, Maria V Zaretskaia, Joseph A Dimicco, Pamela J Durant, Christian T Ross, Daniel E Rusyniak. Independent of 5-HT1A receptors, neurons in the paraventricular hypothalamus mediate ACTH responses from MDMA.
Neuroscience letters.
2013 Oct; 555(?):42-6. doi:
10.1016/j.neulet.2013.07.053. [PMID: 23933156] - Kazuaki Nakada, Mamie Yoshikawa, Soichiro Ide, Akihiro Suemasa, Shuhei Kawamura, Takaaki Kobayashi, Eiji Masuda, Yoshihiko Ito, Wataru Hayakawa, Takahiro Katayama, Shizuo Yamada, Mitsuhiro Arisawa, Masabumi Minami, Satoshi Shuto. Cyclopropane-based conformational restriction of GABA by a stereochemical diversity-oriented strategy: identification of an efficient lead for potent inhibitors of GABA transports.
Bioorganic & medicinal chemistry.
2013 Sep; 21(17):4938-50. doi:
10.1016/j.bmc.2013.06.063. [PMID: 23886812] - Yang-Hee Jung, Ri-Ra Ha, Seung-Hwan Kwon, Sa-Ik Hong, Kun-Ho Lee, Sun-Yeou Kim, Seok-Yong Lee, Choon-Gon Jang. Anxiolytic effects of Julibroside C1 isolated from Albizzia julibrissin in mice.
Progress in neuro-psychopharmacology & biological psychiatry.
2013 Jul; 44(?):184-92. doi:
10.1016/j.pnpbp.2013.02.012. [PMID: 23481219] - Julia Cassani, Anna G Escalona Araujo, Mariano Martínez-Vázquez, Norberto Manjarrez, Julia Moreno, Rosa Estrada-Reyes. Anxiolytic-like and antinociceptive effects of 2(S)-neoponcirin in mice.
Molecules (Basel, Switzerland).
2013 Jun; 18(7):7584-99. doi:
10.3390/molecules18077584. [PMID: 23812250] - Tomohide Hori, Lindsay B Gardner, Toshiyuki Hata, Feng Chen, Ann-Marie T Baine, Shinji Uemoto, Justin H Nguyen. Pretreatment of liver grafts in vivo by γ-aminobutyric acid receptor regulation reduces cold ischemia/warm reperfusion injury in rat.
Annals of transplantation.
2013 Jun; 18(?):299-313. doi:
10.12659/aot.883955. [PMID: 23792534] - Audrey Dagorn, Annelise Chapalain, Lily Mijouin, Mélanie Hillion, Cécile Duclairoir-Poc, Sylvie Chevalier, Laure Taupin, Nicole Orange, Marc G J Feuilloley. Effect of GABA, a bacterial metabolite, on Pseudomonas fluorescens surface properties and cytotoxicity.
International journal of molecular sciences.
2013 Jun; 14(6):12186-204. doi:
10.3390/ijms140612186. [PMID: 23743829] - Tomohide Hori, Lindsay B Gardner, Florence Chen, Ann-Marie T Baine, Toshiyuki Hata, Shinji Uemoto, Justin H Nguyen. Liver graft pretreated in vivo or ex vivo by γ-aminobutyric acid receptor regulation.
The Journal of surgical research.
2013 Jun; 182(1):166-75. doi:
10.1016/j.jss.2012.08.055. [PMID: 23010512] - Morteza Kosari-Nasab, Shirin Babri, Laleh Fatehi-Gharehlar, Mohammad-Hossein Doosti, Sara Pakzad. Involvement of GABAergic system in regulation of the anxiolytic- and antidepressant-like effects of Scrophularia striata extract in rats.
Pharmaceutical biology.
2013 May; 51(5):581-8. doi:
10.3109/13880209.2012.749924. [PMID: 23373710] - María del C García, Yanina C Godoy, Stella M Celuch. Impaired hypotensive responses induced by intrathecally injected drugs in fructose-fed rats.
European journal of pharmacology.
2013 Apr; 706(1-3):17-24. doi:
10.1016/j.ejphar.2013.02.037. [PMID: 23499700] - Mohammad Hadi Gharedaghi, Mehrak Javadi-Paydar, Yashar Yousefzadeh-Fard, Mohammad Salehi-Sadaghiani, Pouya Javadian, Nahid Fakhraei, Seyed Mohammad Tavangar, Ahmad Reza Dehpour. Muscimol delays lipopolysaccharide-induced preterm delivery in mice: role of GABA(A) receptors and nitric oxide.
The journal of maternal-fetal & neonatal medicine : the official journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians.
2013 Jan; 26(1):36-43. doi:
10.3109/14767058.2012.722715. [PMID: 22913283] - Rohit Ramchandra, Sally G Hood, Robert Frithiof, Michael J McKinley, Clive N May. The role of the paraventricular nucleus of the hypothalamus in the regulation of cardiac and renal sympathetic nerve activity in conscious normal and heart failure sheep.
The Journal of physiology.
2013 Jan; 591(1):93-107. doi:
10.1113/jphysiol.2012.236059. [PMID: 22615431] - Hong-Yan Liu, Yu-Xiang Li, Yin-Ju Hao, Hai-Yan Wang, Xiu-Ying Dai, Tao Sun, Jian-Qiang Yu. Effects of oxymatrine on the neuropathic pain induced by chronic constriction injury in mice.
CNS neuroscience & therapeutics.
2012 Dec; 18(12):1030-2. doi:
10.1111/cns.12026. [PMID: 23164255] - B A Carillo, E B Oliveira-Sales, M Andersen, S Tufik, D Hipolide, A A Santos, P J Tucci, C T Bergamaschi, R R Campos. Changes in GABAergic inputs in the paraventricular nucleus maintain sympathetic vasomotor tone in chronic heart failure.
Autonomic neuroscience : basic & clinical.
2012 Nov; 171(1-2):41-8. doi:
10.1016/j.autneu.2012.10.005. [PMID: 23146621] - H-Y Xu, Y-J Liu, M-Y Xu, Y-H Zhang, J-X Zhang, Y-J Wu. Inactivation of the bed nucleus of the stria terminalis suppresses the innate fear responses of rats induced by the odor of cat urine.
Neuroscience.
2012 Sep; 221(?):21-7. doi:
10.1016/j.neuroscience.2012.06.056. [PMID: 22766237] - Qin Chen, Peter D Yim, Nina Yuan, Juliette Johnson, James M Cook, Steve Smith, Cristian Ionescu-Zanetti, Zhi-Jian Wang, Leggy A Arnold, Charles W Emala. Comparison of cell expression formats for the characterization of GABA(A) channels using a microfluidic patch clamp system.
Assay and drug development technologies.
2012 Aug; 10(4):325-35. doi:
10.1089/adt.2011.415. [PMID: 22574655] - Jan Stříbrný, Miloš Sokol, Barbora Merová, Peter Ondra. GC/MS determination of ibotenic acid and muscimol in the urine of patients intoxicated with Amanita pantherina.
International journal of legal medicine.
2012 Jul; 126(4):519-24. doi:
10.1007/s00414-011-0599-9. [PMID: 21751026] - Francisco Garcia-Oscos, Humberto Salgado, Shawn Hall, Feba Thomas, George E Farmer, Jorge Bermeo, Luis Charles Galindo, Ruben D Ramirez, Santosh D'Mello, Stefan Rose-John, Marco Atzori. The stress-induced cytokine interleukin-6 decreases the inhibition/excitation ratio in the rat temporal cortex via trans-signaling.
Biological psychiatry.
2012 Apr; 71(7):574-82. doi:
10.1016/j.biopsych.2011.11.018. [PMID: 22196984] - Andrea J Hickey, James N Reynolds, Richard J Beninger. Post-weaning social isolation and subchronic NMDA glutamate receptor blockade: effects on locomotor activity and GABA signaling in the rat suggest independent mechanisms.
Pharmacology, biochemistry, and behavior.
2012 Apr; 101(2):231-8. doi:
10.1016/j.pbb.2012.01.015. [PMID: 22293110] - Pedro Garrido, Marta De Blas, Elena Giné, Ángel Santos, Francisco Mora. Aging impairs the control of prefrontal cortex on the release of corticosterone in response to stress and on memory consolidation.
Neurobiology of aging.
2012 Apr; 33(4):827.e1-9. doi:
10.1016/j.neurobiolaging.2011.06.011. [PMID: 21794953] - Jobin Mathew, Savitha Balakrishnan, Sherin Antony, Pretty Mary Abraham, C S Paulose. Decreased GABA receptor in the cerebral cortex of epileptic rats: effect of Bacopa monnieri and Bacoside-A.
Journal of biomedical science.
2012 Feb; 19(?):25. doi:
10.1186/1423-0127-19-25. [PMID: 22364254] - Simon Trent, Alison Dennehy, Heather Richardson, Obah A Ojarikre, Paul S Burgoyne, Trevor Humby, William Davies. Steroid sulfatase-deficient mice exhibit endophenotypes relevant to attention deficit hyperactivity disorder.
Psychoneuroendocrinology.
2012 Feb; 37(2):221-9. doi:
10.1016/j.psyneuen.2011.06.006. [PMID: 21723668] - Puneet Kumar, Harikesh Kalonia, Anil Kumar. Possible GABAergic mechanism in the neuroprotective effect of gabapentin and lamotrigine against 3-nitropropionic acid induced neurotoxicity.
European journal of pharmacology.
2012 Jan; 674(2-3):265-74. doi:
10.1016/j.ejphar.2011.11.030. [PMID: 22154757] - Spencer D Watts, Katherine L Suchland, Susan G Amara, Susan L Ingram. A sensitive membrane-targeted biosensor for monitoring changes in intracellular chloride in neuronal processes.
PloS one.
2012; 7(4):e35373. doi:
10.1371/journal.pone.0035373. [PMID: 22506078] - Xin Zhang, Bin Cheng, Xianghong Jing, Yongfa Qiao, Xinyan Gao, Huijuan Yu, Bing Zhu, Haifa Qiao. NMDA Receptors of Gastric-Projecting Neurons in the Dorsal Motor Nucleus of the Vagus Mediate the Regulation of Gastric Emptying by EA at Weishu (BL21).
Evidence-based complementary and alternative medicine : eCAM.
2012; 2012(?):583479. doi:
10.1155/2012/583479. [PMID: 22654955] - David T Thwaites, Catriona M H Anderson. The SLC36 family of proton-coupled amino acid transporters and their potential role in drug transport.
British journal of pharmacology.
2011 Dec; 164(7):1802-16. doi:
10.1111/j.1476-5381.2011.01438.x. [PMID: 21501141] - Badr Mostafa Ibrahim, Abdel A Abdel-Rahman. Role of brainstem GABAergic signaling in central cannabinoid receptor evoked sympathoexcitation and pressor responses in conscious rats.
Brain research.
2011 Sep; 1414(?):1-9. doi:
10.1016/j.brainres.2011.07.046. [PMID: 21840505] - E Stone, J H Coote, J Allard, T A Lovick. GABAergic control of micturition within the periaqueductal grey matter of the male rat.
The Journal of physiology.
2011 Apr; 589(Pt 8):2065-78. doi:
10.1113/jphysiol.2010.202614. [PMID: 21486804] - Martin M Schmidt, Akhilesh Sharma, Fabrizio Schifano, Charlotte Feinmann. "Legal highs" on the net-Evaluation of UK-based Websites, products and product information.
Forensic science international.
2011 Mar; 206(1-3):92-7. doi:
10.1016/j.forsciint.2010.06.030. [PMID: 20650576] - Adak Nasiripourdori, Valérie Taly, Thomas Grutter, Antoine Taly. From toxins targeting ligand gated ion channels to therapeutic molecules.
Toxins.
2011 03; 3(3):260-93. doi:
10.3390/toxins3030260. [PMID: 22069709] - Anil Kumar, Anant Singh, Puneet Kumar. Possible involvement of GABAergic mechanism in protective effect of melatonin against sleep deprivation-induced behavior modification and oxidative damage in mice.
Indian journal of experimental biology.
2011 Mar; 49(3):211-8. doi:
. [PMID: 21452601] - Leonardo Dionisio, María José De Rosa, Cecilia Bouzat, María Del Carmen Esandi. An intrinsic GABAergic system in human lymphocytes.
Neuropharmacology.
2011 Feb; 60(2-3):513-9. doi:
10.1016/j.neuropharm.2010.11.007. [PMID: 21093461] - Shan Jiang, Bei Miao, Xuejun Song, Zhenglin Jiang. Inactivation of GABA(A) receptor reduces ginsenoside Rb3 neuroprotection in mouse hippocampal slices after oxygen-glucose deprivation.
Journal of ethnopharmacology.
2011 Jan; 133(2):914-6. doi:
10.1016/j.jep.2010.10.030. [PMID: 20969942] - Raina D Pang, Zhuo Wang, Lauren P Klosinski, Yumei Guo, David H Herman, Tansu Celikel, Hong Wei Dong, Daniel P Holschneider. Mapping functional brain activation using [14C]-iodoantipyrine in male serotonin transporter knockout mice.
PloS one.
2011; 6(8):e23869. doi:
10.1371/journal.pone.0023869. [PMID: 21886833] - Ken'ichi Yamaguchi, Hitoshi Hama. Changes in vasopressin release and autonomic function induced by manipulating forebrain GABAergic signaling under euvolemia and hypovolemia in conscious rats.
Endocrine journal.
2011; 58(7):559-73. doi:
10.1507/endocrj.k11e-002. [PMID: 21532213] - Tadachika Koganezawa, Yuri Shimomura, Naohito Terui. The viscerosympathetic response in rabbits is mediated by GABAergic and glutamatergic inputs into the sympathetic premotor neurons of the rostral ventrolateral medulla.
Experimental physiology.
2010 Nov; 95(11):1061-70. doi:
10.1113/expphysiol.2010.054668. [PMID: 20729268] - Sachin A Paranjape, Owen Chan, Wanling Zhu, Adam M Horblitt, Ewan C McNay, James A Cresswell, Jonathan S Bogan, Rory J McCrimmon, Robert S Sherwin. Influence of insulin in the ventromedial hypothalamus on pancreatic glucagon secretion in vivo.
Diabetes.
2010 Jun; 59(6):1521-7. doi:
10.2337/db10-0014. [PMID: 20299468] - Kelly R Wagoner, Cynthia Czajkowski. Stoichiometry of expressed alpha(4)beta(2)delta gamma-aminobutyric acid type A receptors depends on the ratio of subunit cDNA transfected.
The Journal of biological chemistry.
2010 May; 285(19):14187-94. doi:
10.1074/jbc.m110.104257. [PMID: 20233712] - Martin Mortensen, Bjarke Ebert, Keith Wafford, Trevor G Smart. Distinct activities of GABA agonists at synaptic- and extrasynaptic-type GABAA receptors.
The Journal of physiology.
2010 Apr; 588(Pt 8):1251-68. doi:
10.1113/jphysiol.2009.182444. [PMID: 20176630] - Richard J Beninger, Jonathan Beuk, Tomek J Banasikowski, Michael van Adel, Gregory A Boivin, James N Reynolds. Subchronic phencyclidine in rats: alterations in locomotor activity, maze performance, and GABA(A) receptor binding.
Behavioural pharmacology.
2010 Feb; 21(1):1-10. doi:
10.1097/fbp.0b013e3283347091. [PMID: 19949321] - Joseph L Hunt, Dmitry V Zaretsky, Sumit Sarkar, Joseph A Dimicco. Dorsomedial hypothalamus mediates autonomic, neuroendocrine, and locomotor responses evoked from the medial preoptic area.
American journal of physiology. Regulatory, integrative and comparative physiology.
2010 Jan; 298(1):R130-40. doi:
10.1152/ajpregu.00574.2009. [PMID: 19923355] - David N Ruskin, Masahito Kawamura, Susan A Masino. Reduced pain and inflammation in juvenile and adult rats fed a ketogenic diet.
PloS one.
2009 Dec; 4(12):e8349. doi:
10.1371/journal.pone.0008349. [PMID: 20041135] - Anil Kumar, Anant Singh. Possible involvement of GABAergic mechanism in protective effect of melatonin against sleep deprivation-induced behaviour modification and oxidative damage in mice.
Fundamental & clinical pharmacology.
2009 Aug; 23(4):439-48. doi:
10.1111/j.1472-8206.2009.00737.x. [PMID: 19709322] - Yasuyuki Suzuki, Mitsutoshi Yuzurihara, Tomoko Hibino, Shingo Yano, Yoshio Kase. Aqueous extract of Asiasari radix inhibits formalin-induced hyperalgesia via NMDA receptors.
Journal of ethnopharmacology.
2009 May; 123(1):128-33. doi:
10.1016/j.jep.2009.02.005. [PMID: 19429351] - Yuan Ma, Hong Ma, Jae Soon Eun, Sang-Yoon Nam, Yun-Bae Kim, Jin-Tae Hong, Myung-Koo Lee, Ki-Wan Oh. Methanol extract of Longanae Arillus augments pentobarbital-induced sleep behaviors through the modification of GABAergic systems.
Journal of ethnopharmacology.
2009 Mar; 122(2):245-50. doi:
10.1016/j.jep.2009.01.012. [PMID: 19330921] - Min Zhang, Katherine Clarke, Huijun Zhong, Cathy Vollmer, Colin A Nurse. Postsynaptic action of GABA in modulating sensory transmission in co-cultures of rat carotid body via GABA(A) receptors.
The Journal of physiology.
2009 Jan; 587(2):329-44. doi:
10.1113/jphysiol.2008.165035. [PMID: 19029183] - Hitoshi Ishibashi, Kenzo Hirao, Junya Yamaguchi, Junichi Nabekura. Inhibition of chloride outward transport by gadolinium in cultured rat spinal cord neurons.
Neurotoxicology.
2009 Jan; 30(1):155-9. doi:
10.1016/j.neuro.2008.10.003. [PMID: 19007810] - Emilie Sapin, Damien Lapray, Anne Bérod, Romain Goutagny, Lucienne Léger, Pascal Ravassard, Olivier Clément, Lucie Hanriot, Patrice Fort, Pierre-Hervé Luppi. Localization of the brainstem GABAergic neurons controlling paradoxical (REM) sleep.
PloS one.
2009; 4(1):e4272. doi:
10.1371/journal.pone.0004272. [PMID: 19169414] - L O Margatho, L L K Elias, J Antunes-Rodrigues. GABA in the central amygdaloid nucleus modulates the electrolyte excretion and hormonal responses to blood volume expansion in rats.
Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologicas.
2009 Jan; 42(1):114-21. doi:
10.1590/s0100-879x2009000100016. [PMID: 19219304] - Dubravka Svob Strac, Josipa Vlainić, Maja Jazvinsćak Jembrek, Danka Pericić. Differential effects of diazepam treatment and withdrawal on recombinant GABAA receptor expression and functional coupling.
Brain research.
2008 Dec; 1246(?):29-40. doi:
10.1016/j.brainres.2008.09.093. [PMID: 18955034] - Gang Zheng, Yaoming Chen, Xueping Zhang, Tongjian Cai, Mingchao Liu, Fang Zhao, Wenjing Luo, Jingyuan Chen. Acute cold exposure and rewarming enhanced spatial memory and activated the MAPK cascades in the rat brain.
Brain research.
2008 Nov; 1239(?):171-80. doi:
10.1016/j.brainres.2008.08.057. [PMID: 18789908] - A Singh, A Kumar. Possible GABAergic modulation in the protective effect of allopregnanolone on sleep deprivation-induced anxiety-like behavior and oxidative damage in mice.
Methods and findings in experimental and clinical pharmacology.
2008 Nov; 30(9):681-9. doi:
10.1358/mf.2008.30.9.1186076. [PMID: 19229376] - Barbora Merova, Peter Ondra, Marie Stankova, Ivo Valka. Isolation and identification of the Amanita muscaria and Amanita pantherina toxins in human urine.
Neuro endocrinology letters.
2008 Oct; 29(5):744-8. doi:
NULL. [PMID: 18987593] - Andries Kalsbeek, Ewout Foppen, Ingrid Schalij, Caroline Van Heijningen, Jan van der Vliet, Eric Fliers, Ruud M Buijs. Circadian control of the daily plasma glucose rhythm: an interplay of GABA and glutamate.
PloS one.
2008 Sep; 3(9):e3194. doi:
10.1371/journal.pone.0003194. [PMID: 18791643] - Ken'ichi Yamaguchi, Takaho Yamada. Roles of forebrain GABA receptors in controlling vasopressin secretion and related phenomena under basal and hyperosmotic circumstances in conscious rats.
Brain research bulletin.
2008 Sep; 77(1):61-9. doi:
10.1016/j.brainresbull.2008.04.009. [PMID: 18639747] - Rodrigo C A de Menezes, Dmitry V Zaretsky, Sumit Sarkar, Marco A P Fontes, Joseph A Dimicco. Microinjection of muscimol into the periaqueductal gray suppresses cardiovascular and neuroendocrine response to air jet stress in conscious rats.
American journal of physiology. Regulatory, integrative and comparative physiology.
2008 Sep; 295(3):R881-90. doi:
10.1152/ajpregu.00181.2008. [PMID: 18650321] - Munish Kumar, Neetu Tyagi, Karni S Moshal, Utpal Sen, S B Pushpakumar, Thomas Vacek, David Lominadze, Suresh C Tyagi. GABAA receptor agonist mitigates homocysteine-induced cerebrovascular remodeling in knockout mice.
Brain research.
2008 Jul; 1221(?):147-53. doi:
10.1016/j.brainres.2008.04.021. [PMID: 18547546] - Maja Jazvinsćak Jembrek, Dubravka Svob Strac, Josipa Vlainić, Danka Pericić. The role of transcriptional and translational mechanisms in flumazenil-induced up-regulation of recombinant GABA(A) receptors.
Neuroscience research.
2008 Jul; 61(3):234-41. doi:
10.1016/j.neures.2008.03.005. [PMID: 18453026] - Dana Ferraris, Bridget Duvall, Yao-Sen Ko, Ajit G Thomas, Camilo Rojas, Pavel Majer, Kenji Hashimoto, Takashi Tsukamoto. Synthesis and biological evaluation of D-amino acid oxidase inhibitors.
Journal of medicinal chemistry.
2008 Jun; 51(12):3357-9. doi:
10.1021/jm800200u. [PMID: 18507366] - Gary Matthews, Peter Sterling. Evidence that vesicles undergo compound fusion on the synaptic ribbon.
The Journal of neuroscience : the official journal of the Society for Neuroscience.
2008 May; 28(21):5403-11. doi:
10.1523/jneurosci.0935-08.2008. [PMID: 18495874] - Yuan Ma, Huishan Han, Sang-Yoon Nam, Yun-Bae Kim, Jin-Tae Hong, Yeo-Pyo Yun, Ki-Wan Oh. Cyclopeptide alkaloid fraction from Zizyphi Spinosi Semen enhances pentobarbital-induced sleeping behaviors.
Journal of ethnopharmacology.
2008 May; 117(2):318-24. doi:
10.1016/j.jep.2008.02.006. [PMID: 18353574] - Anant Singh, Anil Kumar. Protective effect of alprazolam against sleep deprivation-induced behavior alterations and oxidative damage in mice.
Neuroscience research.
2008 Apr; 60(4):372-9. doi:
10.1016/j.neures.2007.12.003. [PMID: 18280601] - Anil Kumar, Richa Goyal. Possible GABAergic modulation in the protective effect of zolpidem in acute hypoxic stress-induced behavior alterations and oxidative damage.
Neurochemical research.
2008 Mar; 33(3):370-7. doi:
10.1007/s11064-007-9431-9. [PMID: 17768679] - Ralph Nelson, Anna M Bender, Victoria P Connaughton. Transporter-mediated GABA responses in horizontal and bipolar cells of zebrafish retina.
Visual neuroscience.
2008 Mar; 25(2):155-65. doi:
10.1017/s0952523808080310. [PMID: 18442438] - Anil Kumar, Richa Goyal. Gabapentin attenuates acute hypoxic stress-induced behavioral alterations and oxidative damage in mice: possible involvement of GABAergic mechanism.
Indian journal of experimental biology.
2008 Mar; 46(3):159-63. doi:
". [PMID: 18432054] - Everton Heidi Kimura, Lisandra B Oliveira, Débora S A Colombari, Laurival A De Luca, José V Menani, João Carlos Callera. Sodium intake by hyperosmotic rats treated with a GABA(A) receptor agonist into the lateral parabrachial nucleus.
Brain research.
2008 Jan; 1190(?):86-93. doi:
10.1016/j.brainres.2007.11.004. [PMID: 18048006] - Satinder S Sarang, Svetlana M Lukyanova, Daniel D Brown, Brian S Cummings, Steven R Gullans, Rick G Schnellmann. Identification, coassembly, and activity of gamma-aminobutyric acid receptor subunits in renal proximal tubular cells.
The Journal of pharmacology and experimental therapeutics.
2008 Jan; 324(1):376-82. doi:
10.1124/jpet.107.129957. [PMID: 17959749] - Neetu Tyagi, Karni S Moshal, Suresh C Tyagi, David Lominadze. gamma-Aminbuturic acid A receptor mitigates homocysteine-induced endothelial cell permeability.
Endothelium : journal of endothelial cell research.
2007 Nov; 14(6):315-23. doi:
10.1080/10623320701746164. [PMID: 18080868]