Licoflavone C (BioDeep_00000266188)

 

Secondary id: BioDeep_00000229989

PANOMIX_OTCML-2023


代谢物信息卡片


5,7-Dihydroxy-2- (4-hydroxyphenyl) -8- (3-methyl-2-butenyl) -4H-1-benzopyran-4-one

化学式: C20H18O5 (338.1154178)
中文名称: 甘草黄酮C, 甘草黄酮 C
谱图信息: 最多检出来源 () 0%

分子结构信息

SMILES: C(=O)(C=2)c(c1OC2c(c3)ccc(O)c3)c(cc(O)c(CC=C(C)C)1)O
InChI: InChI=1S/C20H18O5/c1-11(2)3-8-14-15(22)9-16(23)19-17(24)10-18(25-20(14)19)12-4-6-13(21)7-5-12/h3-7,9-10,21-23H,8H2,1-2H3

描述信息

同义名列表

5 个代谢物同义名

5,7,4-Trihydroxy-8-prenylflavone; 8-Prenylapigenin; Licoflavone C; 5,7-Dihydroxy-2- (4-hydroxyphenyl) -8- (3-methyl-2-butenyl) -4H-1-benzopyran-4-one; 5,7-Dihydroxy-2-(4-hydroxyphenyl)-8-(3-methyl-2-butenyl)-4H-1-benzopyran-4-one



数据库引用编号

7 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(0)

BioCyc(0)

PlantCyc(0)

代谢反应

0 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

8 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：

  • PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。



文献列表

  • Xian-Sheng Ye, Wen-Jing Tian, Mi Zhou, De-Quan Zeng, Ting Lin, Guang-Hui Wang, Xin-Sheng Yao, Hai-Feng Chen. Prenylated flavonoids from Ficus hirta induces HeLa cells apoptosis via MAPK and AKT signaling pathways. Bioorganic & medicinal chemistry letters. 2021 04; 38(?):127859. doi: 10.1016/j.bmcl.2021.127859. [PMID: 33609662]
  • Atieh Hajirahimkhan, Obinna Mbachu, Charlotte Simmler, Sarah G Ellis, Huali Dong, Dejan Nikolic, David C Lankin, Richard B van Breemen, Shao-Nong Chen, Guido F Pauli, Birgit M Dietz, Judy L Bolton. Estrogen Receptor (ER) Subtype Selectivity Identifies 8-Prenylapigenin as an ERβ Agonist from Glycyrrhiza inflata and Highlights the Importance of Chemical and Biological Authentication. Journal of natural products. 2018 04; 81(4):966-975. doi: 10.1021/acs.jnatprod.7b01070. [PMID: 29641206]
  • Yan-Qiong Guo, Gui-Hua Tang, Lan-Lan Lou, Wei Li, Bei Zhang, Bo Liu, Sheng Yin. Prenylated flavonoids as potent phosphodiesterase-4 inhibitors from Morus alba: Isolation, modification, and structure-activity relationship study. European journal of medicinal chemistry. 2018 Jan; 144(?):758-766. doi: 10.1016/j.ejmech.2017.12.057. [PMID: 29291443]
  • Ming Li, Xuewei Wu, Xiaoning Wang, Tao Shen, Dongmei Ren. Two novel compounds from the root bark of Morus alba L. Natural product research. 2018 Jan; 32(1):36-42. doi: 10.1080/14786419.2017.1327862. [PMID: 28521570]
  • Yan Lin, Yi Kuang, Kai Li, Shuang Wang, Shuai Ji, Kuan Chen, Wei Song, Xue Qiao, Min Ye. Nrf2 activators from Glycyrrhiza inflata and their hepatoprotective activities against CCl4-induced liver injury in mice. Bioorganic & medicinal chemistry. 2017 10; 25(20):5522-5530. doi: 10.1016/j.bmc.2017.08.018. [PMID: 28835349]
  • Yan Lin, Yi Kuang, Kai Li, Shuang Wang, Wei Song, Xue Qiao, Gulnar Sabir, Min Ye. Screening for bioactive natural products from a 67-compound library of Glycyrrhiza inflata. Bioorganic & medicinal chemistry. 2017 07; 25(14):3706-3713. doi: 10.1016/j.bmc.2017.05.009. [PMID: 28522265]
  • Yun-Ze Yin, Rui-Shan Wang, Ri-Dao Chen, Li-Rui Qiao, Lin Yang, Chun-Mei Wang, Jun-Gui Dai. [Chemical constituents from cell suspension cultures of Cudrania tricuspidata]. Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica. 2012 Dec; 37(24):3734-7. doi: . [PMID: 23627169]
  • Hayet Edziri, Maha Mastouri, Mohamed Ali Mahjoub, Zine Mighri, Aouni Mahjoub, Luc Verschaeve. Antibacterial, antifungal and cytotoxic activities of two flavonoids from Retama raetam flowers. Molecules (Basel, Switzerland). 2012 Jun; 17(6):7284-93. doi: 10.3390/molecules17067284. [PMID: 22695233]
  • Elisa Brunelli, Giulia Pinton, Paolo Bellini, Alberto Minassi, Giovanni Appendino, Laura Moro. Flavonoid-induced autophagy in hormone sensitive breast cancer cells. Fitoterapia. 2009 Sep; 80(6):327-32. doi: 10.1016/j.fitote.2009.04.002. [PMID: 19371773]
  • Roberto Scarpato, Letizia Paganucci, Alessandra Bertoli, Lisa Fiore, Luisa Pistelli, Giovanni Federico. Licoflavone C attenuates the genotoxicity of cancer drugs in human peripheral lymphocytes. Phytotherapy research : PTR. 2008 Dec; 22(12):1650-4. doi: 10.1002/ptr.2546. [PMID: 18979523]
  • Mario Dell'Agli, Germana V Galli, Esther Dal Cero, Federica Belluti, Riccardo Matera, Elisa Zironi, Giampiero Pagliuca, Enrica Bosisio. Potent inhibition of human phosphodiesterase-5 by icariin derivatives. Journal of natural products. 2008 Sep; 71(9):1513-7. doi: 10.1021/np800049y. [PMID: 18778098]
  • Dejan Nikolic, Yongmei Li, Lucas R Chadwick, Simonida Grubjesic, Pia Schwab, Peter Metz, Richard B van Breemen. Metabolism of 8-prenylnaringenin, a potent phytoestrogen from hops (Humulus lupulus), by human liver microsomes. Drug metabolism and disposition: the biological fate of chemicals. 2004 Feb; 32(2):272-9. doi: 10.1124/dmd.32.2.272. [PMID: 14744951]