Eucalyptin (BioDeep_00000266167)

natural product PANOMIX_OTCML-2023

代谢物信息卡片

5-Hydroxy-7-methoxy-2- (4-methoxyphenyl) -6,8-dimethyl-4H-1-benzopyran-4-one

化学式: C19H18O5 (326.1154)
中文名称: 桉树素
谱图信息: 最多检出来源 Chinese Herbal Medicine(otcml) 69.08%

分子结构信息

SMILES: c(C(O2)=CC(c(c3O)c2c(c(c3C)OC)C)=O)(c1)ccc(OC)c1
InChI: InChI=1S/C19H18O5/c1-10-17(21)16-14(20)9-15(12-5-7-13(22-3)8-6-12)24-19(16)11(2)18(10)23-4/h5-9,21H,1-4H3

3D Structure

描述信息

Eucalyptin is a natural product found in Myrcia citrifolia, Myrcia glabra, and other organisms with data available.

同义名列表

17 个代谢物同义名

4,7-Dimethoxy-6,8-dimethyl-5-hydroxyflavone; Eucalyptin; 5-hydroxy-4,7-dimethoxy-6,8-dimethylflavone; 5-Hydroxy-7-methoxy-2-(4-methoxyphenyl)-6,8-dimethyl-4H-chromen-4-one; 5-Hydroxy-7-methoxy-2-(4-methoxyphenyl)-6,8-dimethyl-4-benzopyrone; 5-hydroxy-7-methoxy-2-(4-methoxyphenyl)-6,8-dimethylchromen-4-one; 4,7-Dimethoxy-6,8-dimethyl-5-hydroxyflavone; Eucalyptin; Flavone, 5-hydroxy-4,7-dimethoxy-6,8-dimethyl-; 5-hydroxy-7,4-dimethoxy-6,8-dimethylflavone; 5-Hydroxy-7-methoxy-2- (4-methoxyphenyl) -6,8-dimethyl-4H-1-benzopyran-4-one; 5-Hydroxy-7-methoxy-2-(4-methoxyphenyl)-6,8-dimethyl-4H-1-benzopyran-4-one; 4',7-Dimethoxy-6,8-dimethyl-5-hydroxyflavone; 4',7-Dimethoxy-6,8-dimethyl-5-hydroxyflavone; Eucalyptin; 5-hydroxy-4',7-dimethoxy-6,8-dimethylflavone; 5-hydroxy-7,4'-dimethoxy-6,8-dimethylflavone; Flavone, 5-hydroxy-4',7-dimethoxy-6,8-dimethyl-; NHMMAMIRMITGRD-UHFFFAOYSA-N

数据库引用编号

14 个数据库交叉引用编号

PubChem: 76573
Metlin: METLIN49455
ChEMBL: CHEMBL4750729
LipidMAPS: LMPK12111028
MeSH: eucalyptin
ChemIDplus: 0003122881
KNApSAcK: C00003991
CAS: 3122-88-1
MoNA: CCMSLIB00000081748
medchemexpress: HY-N3876
PMhub: MS000213639
Flavonoid: FL3FCBNM0002
LOTUS: LTS0154788
ChEBI: CHEBI:230595

分类词条

代谢反应

0 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

32 个相关的物种来源信息

73722 - Callistemon: LTS0154788
376184 - Callistemon citrinus: 10.1016/J.PHYTOL.2011.08.010
376184 - Callistemon citrinus: 10.1055/S-2006-957706
155884 - Callistemon lanceolatus: 10.1016/J.PHYTOL.2011.08.010
155884 - Callistemon lanceolatus: 10.1055/S-2006-957706
155884 - Callistemon lanceolatus: LTS0154788
3932 - Eucalyptus: LTS0154788
370640 - Eucalyptus cinerea: 10.1071/CH9640464
370640 - Eucalyptus cinerea: LTS0154788
452569 - Eucalyptus cladocalyx: 10.1002/CHIN.200535206
452569 - Eucalyptus cladocalyx: 10.1016/J.PHYTOCHEM.2004.12.018
452569 - Eucalyptus cladocalyx: LTS0154788
34317 - Eucalyptus globulus: 10.1071/CH9640464
34317 - Eucalyptus globulus: LTS0154788
627158 - Eucalyptus robusta: 10.1515/ZNB-1991-0925
627158 - Eucalyptus robusta: LTS0154788
99019 - Eucalyptus saligna: 10.1016/S0305-1978(03)00134-0
99019 - Eucalyptus saligna: LTS0154788
119950 - Eugenia: LTS0154788
1453369 - Eugenia biflora: 10.1016/S0031-9422(00)88490-3
1453369 - Eugenia biflora: LTS0154788
2759 - Eukaryota: LTS0154788
3398 - Magnoliopsida: LTS0154788
375249 - Myrcia: LTS0154788
1134152 - Myrcia citrifolia: 10.1016/S0031-9422(00)88490-3
1134152 - Myrcia citrifolia: LTS0154788
1231864 - Myrcia glabra: 10.1016/S0031-9422(00)88490-3
1231864 - Myrcia glabra: LTS0154788
3931 - Myrtaceae: LTS0154788
35493 - Streptophyta: LTS0154788
58023 - Tracheophyta: LTS0154788
33090 - Viridiplantae: LTS0154788

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：

PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。

亚细胞结构定位		关联基因列表

文献列表

Xiao-Long Hu, Wei Shen, Rong Wang, Huan Long, Quan Wang, Jia-Hao Feng, Thi-Anh Pham, Fei Xiong, Wen-Cai Ye, Hao Wang. Discovery of Eucalyptin C, derived from the fruits of Eucalyptus globulus Labill., as a novel selective PI3Kγ inhibitor for immunosuppressive treatment. Chinese journal of natural medicines. 2021 Nov; 19(11):844-855. doi: 10.1016/s1875-5364(21)60111-5. [PMID: 34844723]
Tarannum Naz, Joanne Packer, Ping Yin, Joseph J Brophy, Hans Wohlmuth, Dane E Renshaw, Joshua Smith, Yaegl Community Elders, Subramanyam R Vemulpad, Joanne F Jamie. Bioactivity and chemical characterisation of Lophostemon suaveolens--an endemic Australian Aboriginal traditional medicinal plant. Natural product research. 2016; 30(6):693-6. doi: 10.1080/14786419.2015.1038260. [PMID: 25942679]
Wen Ouyang, Xiao-ai Zhu, Cui-xia He, Xue-xiang Chen, Shu-min Ye, Shan Peng, Yong Cao. [Chemical Constituents from Ethyl Acetate Extract of Psidium guajava Leaves (II)]. Zhong yao cai = Zhongyaocai = Journal of Chinese medicinal materials. 2015 Aug; 38(8):1649-52. doi: . [PMID: 26983237]
So-Young Park, Ji-Youn Lim, Wonsik Jeong, Seong Su Hong, Young Taek Yang, Bang Yeon Hwang, Dongho Lee. C-methylflavonoids isolated from Callistemon lanceolatus protect PC12 cells against Abeta-induced toxicity. Planta medica. 2010 Jun; 76(9):863-8. doi: 10.1055/s-0029-1240801. [PMID: 20101562]
Simin D Maleknia, Teresa M Vail, Robert B Cody, David O Sparkman, Tina L Bell, Mark A Adams. Temperature-dependent release of volatile organic compounds of eucalypts by direct analysis in real time (DART) mass spectrometry. Rapid communications in mass spectrometry : RCM. 2009 Aug; 23(15):2241-6. doi: 10.1002/rcm.4133. [PMID: 19551840]
T Takahashi, R Kokubo, M Sakaino. Antimicrobial activities of eucalyptus leaf extracts and flavonoids from Eucalyptus maculata. Letters in applied microbiology. 2004; 39(1):60-4. doi: 10.1111/j.1472-765x.2004.01538.x. [PMID: 15189289]
S D Sarker, Z Latif, R J Nash. Application of gradient-enhanced nuclear Overhauser effect spectroscopy GOESY) in the structure elucidation of plant secondary metabolites. Phytochemical analysis : PCA. 2001 Jan; 12(1):23-7. doi: 10.1002/1099-1565(200101/02)12:1<23::aid-pca551>3.0.co;2-e. [PMID: 11704958]