Isookanin (BioDeep_00000250509)

   

PANOMIX_OTCML-2023


代谢物信息卡片


(2S)-2-(3,4-dihydroxyphenyl)-7,8-dihydroxy-3,4-dihydro-2H-1-benzopyran-4-one

化学式: C15H12O6 (288.06338519999997)
中文名称: 异奥卡宁, 异奥卡宁
谱图信息: 最多检出来源 () 0%

分子结构信息

SMILES: C1(O)=C(O)C2OC(C3C=C(O)C(O)=CC=3)CC(=O)C=2C=C1
InChI: InChI=1S/C15H12O6/c16-9-3-1-7(5-12(9)19)13-6-11(18)8-2-4-10(17)14(20)15(8)21-13/h1-5,13,16-17,19-20H,6H2

描述信息

Isookanin is a natural product found in Acacia melanoxylon, Canarium album, and other organisms with data available.
Isookanin can be used for the research of various illnesses including cancers, skin rashes, snake and insects bites, diabetes mellitus, diarrhoea. Isookanin acts as an anti-viral agent against HSV and varicella-zoster virus (VZV). Antioxidant activity[1][2].

同义名列表

6 个代谢物同义名

Isookanin; (2S)-2-(3,4-dihydroxyphenyl)-7,8-dihydroxy-3,4-dihydro-2H-1-benzopyran-4-one; (2S)-2-(3,4-dihydroxyphenyl)-7,8-dihydroxy-2,3-dihydrochromen-4-one; (s)-2-(3,4-dihydroxyphenyl)-7,8 dihydroxychroman-4-one; (S)-2-(3,4-Dihydroxyphenyl)-7,8-dihydroxychroman-4-one; 3,4,7,8-Tetrahydroxyflavanone



数据库引用编号

10 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(0)

BioCyc(0)

PlantCyc(0)

代谢反应

0 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

4 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：

  • PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。



文献列表

  • Rong Zhang, Lili Teng, Yi Zhong, Pei Ma, Lijia Xu, Peigen Xiao. Neuroprotection of isookanin against MPTP-induced cell death of SH-SY5Y cells via BCL2/BAX and PI3K/AKT pathways. Psychopharmacology. 2023 May; ?(?):. doi: 10.1007/s00213-023-06383-x. [PMID: 37256377]
  • Young Hye Seo, Tuy An Trinh, Seung Mok Ryu, Hyo Seon Kim, Goya Choi, Byeong Cheol Moon, Sang Hee Shim, Dae Sik Jang, Dongho Lee, Ki Sung Kang, Jun Lee. Chemical Constituents from the Aerial Parts of Elsholtzia ciliata and Their Protective Activities on Glutamate-Induced HT22 Cell Death. Journal of natural products. 2020 10; 83(10):3149-3155. doi: 10.1021/acs.jnatprod.0c00756. [PMID: 32991171]
  • Shing-Chung Lam, Sio-Fong Lam, Jing Zhao, Shao-Ping Li. Rapid Identification and Comparison of Compounds with Antioxidant Activity in Coreopsis tinctoria Herbal Tea by High-Performance Thin-Layer Chromatography Coupled with DPPH Bioautography and Densitometry. Journal of food science. 2016 Sep; 81(9):C2218-23. doi: 10.1111/1750-3841.13402. [PMID: 27516219]
  • Danish Ahmed, Vikas Kumar, Manju Sharma, Amita Verma. Target guided isolation, in-vitro antidiabetic, antioxidant activity and molecular docking studies of some flavonoids from Albizzia Lebbeck Benth. bark. BMC complementary and alternative medicine. 2014 May; 14(?):155. doi: 10.1186/1472-6882-14-155. [PMID: 24886138]
  • Xiao-Wei Yang, Min-Zhu Huang, Yong-Sheng Jin, Lian-Na Sun, Yan Song, Hai-Sheng Chen. Phenolics from Bidens bipinnata and their amylase inhibitory properties. Fitoterapia. 2012 Oct; 83(7):1169-75. doi: 10.1016/j.fitote.2012.07.005. [PMID: 22814126]
  • Teresa Dias, Hélder Mota-Filipe, Bo Liu, Peter Jones, Peter J Houghton, Alexandra Paulo. Recovery of oral glucose tolerance by Wistar rats after treatment with Coreopsis tinctoria infusion. Phytotherapy research : PTR. 2010 May; 24(5):699-705. doi: 10.1002/ptr.2998. [PMID: 19827015]
  • Mary H Grace, George R Wilsonb, Fayez E Kandil, Eugene Dimitriadis, Robert M Coates. Characteristic flavonoids from Acacia burkittii and A. acuminata heartwoods and their differential cytotoxicity to normal and leukemia cells. Natural product communications. 2009 Jan; 4(1):69-76. doi: NULL. [PMID: 19370878]
  • Mee Jung Jung, Sam Sik Kang, Hyun Ah Jung, Goon Ja Kim, Jae Sue Choi. Isolation of flavonoids and a cerebroside from the stem bark of Albizzia julibrissin. Archives of pharmacal research. 2004 Jun; 27(6):593-9. doi: 10.1007/bf02980155. [PMID: 15283458]