Cotinine (BioDeep_00000230851)

   

natural product PANOMIX_OTCML-2023


代谢物信息卡片


(5S)-1-methyl-5-pyridin-3-ylpyrrolidin-2-one

化学式: C10H12N2O (176.095)
中文名称: 可替宁, 可铁宁, 可的宁, 可替丁, S-(-)-可替宁, (-)-可替宁
谱图信息: 最多检出来源 Homo sapiens(otcml) 41.85%

Reviewed

Last reviewed on 2024-08-05.

Cite this Page

Cotinine. BioDeep Database v3. PANOMIX ltd, a top metabolomics service provider from China. https://query.biodeep.cn/s/cotinine (retrieved 2025-01-31) (BioDeep RN: BioDeep_00000230851). Licensed under the Attribution-Noncommercial 4.0 International License (CC BY-NC 4.0).

分子结构信息

SMILES: CN1C(=O)CCC1c1cccnc1
InChI: InChI=1S/C10H12N2O/c1-12-9(4-5-10(12)13)8-3-2-6-11-7-8/h2-3,6-7,9H,4-5H2,1H3

描述信息

(-)-cotinine is an N-alkylpyrrolidine that consists of N-methylpyrrolidinone bearing a pyridin-3-yl substituent at position C-5 (the 5S-enantiomer). It is an alkaloid commonly found in Nicotiana tabacum. It has a role as a biomarker, an antidepressant, a plant metabolite and a human xenobiotic metabolite. It is a N-alkylpyrrolidine, a member of pyridines, a pyrrolidine alkaloid and a member of pyrrolidin-2-ones.
Cotinine is a natural product found in Haloxylon persicum and Nicotiana tabacum with data available.
Cotinine is the major metabolite of nicotine.
The N-glucuronide conjugate of cotinine is a major urinary metabolite of NICOTINE. It thus serves as a biomarker of exposure to tobacco SMOKING. It has CNS stimulating properties.
An N-alkylpyrrolidine that consists of N-methylpyrrolidinone bearing a pyridin-3-yl substituent at position C-5 (the 5S-enantiomer). It is an alkaloid commonly found in Nicotiana tabacum.
C78272 - Agent Affecting Nervous System > C47796 - Cholinergic Agonist > C73579 - Nicotinic Agonist
D019995 - Laboratory Chemicals > D007202 - Indicators and Reagents
CONFIDENCE standard compound; INTERNAL_ID 511; DATASET 20200303_ENTACT_RP_MIX506; DATA_PROCESSING MERGING RMBmix ver. 0.2.7; DATA_PROCESSING PRESCREENING Shinyscreen ver. 0.8.0; ORIGINAL_ACQUISITION_NO 1258; ORIGINAL_PRECURSOR_SCAN_NO 1257
CONFIDENCE standard compound; INTERNAL_ID 511; DATASET 20200303_ENTACT_RP_MIX506; DATA_PROCESSING MERGING RMBmix ver. 0.2.7; DATA_PROCESSING PRESCREENING Shinyscreen ver. 0.8.0; ORIGINAL_ACQUISITION_NO 1284; ORIGINAL_PRECURSOR_SCAN_NO 1280
CONFIDENCE standard compound; INTERNAL_ID 511; DATASET 20200303_ENTACT_RP_MIX506; DATA_PROCESSING MERGING RMBmix ver. 0.2.7; DATA_PROCESSING PRESCREENING Shinyscreen ver. 0.8.0; ORIGINAL_ACQUISITION_NO 1276; ORIGINAL_PRECURSOR_SCAN_NO 1275
CONFIDENCE standard compound; INTERNAL_ID 511; DATASET 20200303_ENTACT_RP_MIX506; DATA_PROCESSING MERGING RMBmix ver. 0.2.7; DATA_PROCESSING PRESCREENING Shinyscreen ver. 0.8.0; ORIGINAL_ACQUISITION_NO 1277; ORIGINAL_PRECURSOR_SCAN_NO 1275
CONFIDENCE standard compound; INTERNAL_ID 511; DATASET 20200303_ENTACT_RP_MIX506; DATA_PROCESSING MERGING RMBmix ver. 0.2.7; DATA_PROCESSING PRESCREENING Shinyscreen ver. 0.8.0; ORIGINAL_ACQUISITION_NO 1282; ORIGINAL_PRECURSOR_SCAN_NO 1281
CONFIDENCE standard compound; INTERNAL_ID 511; DATASET 20200303_ENTACT_RP_MIX506; DATA_PROCESSING MERGING RMBmix ver. 0.2.7; DATA_PROCESSING PRESCREENING Shinyscreen ver. 0.8.0; ORIGINAL_ACQUISITION_NO 1264; ORIGINAL_PRECURSOR_SCAN_NO 1263
CONFIDENCE Reference Standard (Level 1); INTERNAL_ID 68
CONFIDENCE standard compound; INTERNAL_ID 2283
CONFIDENCE standard compound; INTERNAL_ID 8694
CONFIDENCE standard compound; INTERNAL_ID 8184
relative retention time with respect to 9-anthracene Carboxylic Acid is 0.270
relative retention time with respect to 9-anthracene Carboxylic Acid is 0.268
CONFIDENCE standard compound; INTERNAL_ID 4130
CONFIDENCE standard compound; EAWAG_UCHEM_ID 3282
Cotinine ((-)-Cotinine), an alkaloid in tobacco and a major metabolite of nicotine, is used as a biological indicator to measure the composition of tobacco smoke[1]

同义名列表

65 个代谢物同义名

(5S)-1-Methyl-5-(pyridin-3-yl)pyrrolidin-2-one ((-)-Cotinine); NICOTINE DITARTRATE DIHYDRATE IMPURITY C [EP IMPURITY]; 2-Pyrrolidinone, 1-methyl-5-(3-pyridinyl)-, (5S)-; 2-Pyrrolidinone, 1-methyl-5-(3-pyridinyl)-, (S)-; (5~{S})-1-methyl-5-pyridin-3-yl-pyrrolidin-2-one; (5S)-1-methyl-5-(pyridin-3-yl)pyrrolidin-2-one; (5S)-1-methyl-5-(3-pyridinyl)-2-pyrrolidinone; (S)-1-methyl-5-(pyridin-3-yl)pyrrolidin-2-one; (5S)-1-methyl-5-pyridin-3-yl-pyrrolidin-2-one; (S)-1-Methyl-5-(3-pyridinyl)-2-pyrrolidinone; 5-24-02-00504 (Beilstein Handbook Reference); (5S)-1-methyl-5-pyridin-3-ylpyrrolidin-2-one; (5S)-1-methyl-5-(3-pyridyl)pyrrolidin-2-one; NICOTINE RESINATE IMPURITY C [EP IMPURITY]; (S)-1-Methyl-5-(3-pyridyl)-2-pyrrolidinone; (-)-1-METHYL-5-(3-PYRIDYL)-2-PYRROLIDINONE; S(-)-1-Methyl-5-(3-pyridyl)-2-pyrrolidone; NC01 - Nicotine and Cotinine in Urine; n-methyl-2-(3-pyridyl)-5-pyrrolidone; (-)-Cotinine 1.0 mg/ml in Methanol; NICOTINE IMPURITY C [EP IMPURITY]; (-)-Cotinine, analytical standard; Cotinina [INN-Spanish]; Nicotine EP Impurity C; Cotininum [INN-Latin]; (-)-Cotinine, >=98\\%; NICOTINE IMPURITY C; (-)-Cotinine, 98\\%; Prestwick1_000082; Prestwick0_000082; Prestwick2_000082; Prestwick3_000082; Spectrum3_000700; Spectrum5_000465; (S)-(-)-Cotinine; Spectrum4_001793; COTININE [HSDB]; S-(-)-Cotinine; Cotinine [INN]; Tox21_111219_1; Lopac0_000285; COTININE [MI]; MEGxp0_001870; BPBio1_000006; DivK1c_000861; KBio2_002541; KBio2_005109; Cotinine (-); (-)-Cotinine; KBio2_007677; KBio3_001679; Tox21_111219; Tox21_500285; Tox21_300615; ACon1_000202; (S)-Cotinine; KBio1_000861; IDI1_000861; Cotininum; Cotinina; Cotinine; Scotine; U5H; NIH-10498; Cotinine



数据库引用编号

80 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(0)

BioCyc(2)

PlantCyc(0)

代谢反应

4 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(3)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(1)

30 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：

  • PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。

亚细胞结构定位 关联基因列表


文献列表

  • Ingrid Anne Lie, Kristin Wesnes, Silje S Kvistad, Iman Brouwer, Stig Wergeland, Trygve Holmøy, Rune Midgard, Alla Bru, Astrid Edland, Randi Eikeland, Sonia Gosal, Hanne F Harbo, Grethe Kleveland, Yvonne S Sørenes, Nina Øksendal, Frederik Barkhof, Hugo Vrenken, Kjell-Morten Myhr, Lars Bø, Øivind Torkildsen. The Effect of Smoking on Long-term Gray Matter Atrophy and Clinical Disability in Patients with Relapsing-Remitting Multiple Sclerosis. Neurology(R) neuroimmunology & neuroinflammation. 2022 Sep; 9(5):. doi: 10.1212/nxi.0000000000200008. [PMID: 35738901]
  • Sridhar Chinthakindi, Kurunthachalam Kannan. Variability in urinary concentrations of primary aromatic amines. The Science of the total environment. 2022 Jul; 831(?):154768. doi: 10.1016/j.scitotenv.2022.154768. [PMID: 35341833]
  • Nuozhou Liu, Ying Feng, Yuejuan Zhan, Fang Ma. Relationship between blood cadmium and abdominal aortic calcification: NHANES 2013-2014. Journal of trace elements in medicine and biology : organ of the Society for Minerals and Trace Elements (GMS). 2022 Jul; 72(?):126975. doi: 10.1016/j.jtemb.2022.126975. [PMID: 35344900]
  • Suena H Massey, Ryne Estabrook, Leiszle Lapping-Carr, Rebecca L Newmark, Jean Decety, Katherine L Wisner, Lauren S Wakschlag. Are empathic processes mechanisms of pregnancy's protective effect on smoking? Identification of a novel target for preventive intervention. Social science & medicine (1982). 2022 Jul; 305(?):115071. doi: 10.1016/j.socscimed.2022.115071. [PMID: 35660692]
  • Fawaz Alasmari, Abdullah F Alasmari, Ehab Elzayat, Majed M Alotaibi, Farraj M Alotaibi, Mohamed W Attwa, Fars K Alanazi, Elkhatim H Abdelgadir, Syed Rizwan Ahmad, Faleh Alqahtani, Salim S Al-Rejaie, Musaad A Alshammari. Nicotine and cotinine quantification after a 4-week inhalation of electronic cigarette vapors in male and female mice using UPLC-MS/MS. Saudi medical journal. 2022 Jul; 43(7):678-686. doi: 10.15537/smj.2022.43.7.20220142. [PMID: 35830983]
  • Anna Z Pollack, Jenna R Krall, Shanna H Swan, Germaine M Buck Louis. Does Older Age Modify Associations between Endocrine Disrupting Chemicals and Fecundability?. International journal of environmental research and public health. 2022 06; 19(13):. doi: 10.3390/ijerph19138074. [PMID: 35805732]
  • Joanna Kasprzyk, Wojciech Piekoszewski, Artur Tezyk, Maksymilian Kulza, Ewa Florek. Effects of excessive alcohol drinking on nicotine biotransformation in rats. Scientific reports. 2022 06; 12(1):11066. doi: 10.1038/s41598-022-15199-2. [PMID: 35773467]
  • Caseng Zhang, Kaden Lam, Patrick Hicks, Matt Hicks, Lesley Brennan, Irena Buka, Anne Hicks. Unintentional Tobacco Smoke Exposure in Children. International journal of environmental research and public health. 2022 06; 19(12):. doi: 10.3390/ijerph19127076. [PMID: 35742325]
  • Haley A Mulder, Adam C Pearcy, Matthew S Halquist. Characterization of molecularly imprinted polymers for the extraction of tobacco alkaloids and their metabolites in human urine. Biomedical chromatography : BMC. 2022 Jun; 36(6):e5361. doi: 10.1002/bmc.5361. [PMID: 35261061]
  • Daiana Dalberto, Jodel Alves, Ana Letícia Hilário Garcia, Melissa Rosa de Souza, Angélica Pich Abella, Flávia V Thiesen, Mirian Salvador, Cátia Dos Santos Branco, Norma Marroni, Silvia Bona, Elizangela Schemitt, Fernanda Rabaioli Da Silva, Juliana Da Silva. Exposure in the tobacco fields: Genetic damage and oxidative stress in tobacco farmers occupationally exposed during harvest and grading seasons. Mutation research. Genetic toxicology and environmental mutagenesis. 2022 Jun; 878(?):503485. doi: 10.1016/j.mrgentox.2022.503485. [PMID: 35649679]
  • Akihiro Yoshihara, Keisuke Nakashima, Kana Suwama, Ayuko Odajima, Takayuki Yamaga, Hiroshi Ogawa. Interaction between serum vitamin C levels and smoking on the periodontal condition in older adults. Journal of periodontal research. 2022 Jun; 57(3):587-593. doi: 10.1111/jre.12988. [PMID: 35415888]
  • Ayumi Onoue, Yohei Inaba, Kentaro Machida, Takuya Samukawa, Hiromasa Inoue, Hajime Kurosawa, Hiromitsu Ogata, Naoki Kunugita, Hisamitsu Omori. Association between Fathers' Use of Heated Tobacco Products and Urinary Cotinine Concentrations in Their Spouses and Children. International journal of environmental research and public health. 2022 05; 19(10):. doi: 10.3390/ijerph19106275. [PMID: 35627812]
  • Yukihiro Mori, Mamoru Tanaka, Hana Kozai, Kiyoshi Hotta, Yuka Aoyama, Yukihiro Shigeno, Makoto Aoike, Hatsumi Kawamura, Masato Tsurudome, Morihiro Ito. Antibody response of smokers to the COVID-19 vaccination: Evaluation based on cigarette dependence. Drug discoveries & therapeutics. 2022 May; 16(2):78-84. doi: 10.5582/ddt.2022.01022. [PMID: 35370256]
  • Kevin T Caron, Wanzhe Zhu, John T Bernert, Lanqing Wang, Benjamin C Blount, Kristin Dortch, Ronald E Hunter, Tia Harmon, J Ricky Akins, James Tsai, David M Homa, James L Pirkle, Connie S Sosnoff. Geometric Mean Serum Cotinine Concentrations Confirm a Continued Decline in Secondhand Smoke Exposure among U.S. Nonsmokers-NHANES 2003 to 2018. International journal of environmental research and public health. 2022 05; 19(10):. doi: 10.3390/ijerph19105862. [PMID: 35627398]
  • Lei Yuan, Jingyi Ni. The association between tobacco smoke exposure and vitamin D levels among US general population, 2001-2014: temporal variation and inequalities in population susceptibility. Environmental science and pollution research international. 2022 May; 29(22):32773-32787. doi: 10.1007/s11356-021-17905-5. [PMID: 35020139]
  • Katia Keglberg Hærvig, Kajsa Ugelvig Petersen, Aleksander Giwercman, Karin Sørig Hougaard, Birgit Bjerre Høyer, Christian Lindh, Cecilia Høst Ramlau-Hansen, Anne-Marie Nybo Andersen, Gunnar Toft, Jens Peter Bonde, Sandra Søgaard Tøttenborg. Fetal exposure to maternal cigarette smoking and male reproductive function in young adulthood. European journal of epidemiology. 2022 May; 37(5):525-538. doi: 10.1007/s10654-022-00869-2. [PMID: 35476275]
  • Jonatan Axelsson, Christian H Lindh, Aleksander Giwercman. Exposure to polycyclic aromatic hydrocarbons and nicotine, and associations with sperm DNA fragmentation. Andrology. 2022 05; 10(4):740-748. doi: 10.1111/andr.13170. [PMID: 35234353]
  • Hideaki Ishii, Gary Ngai-Wa Leung, Shozo Yamashita, Shun-Ichi Nagata, Asuka Kushiro, Satoshi Sakai, Kota Toju, Jun Okada, Kazumi Kawasaki, Kanichi Kusano, Isao Kijima-Suda. Identification of potential biomarkers in urine and plasma after consumption of tobacco product in horses. Drug testing and analysis. 2022 May; 14(5):902-914. doi: 10.1002/dta.3242. [PMID: 35195357]
  • Veronika E Espinoza, Priscilla Giner, Isabella Liano, Ian A Mendez, Laura E O'Dell. Sex and age differences in approach behavior toward a port that delivers nicotine vapor. Journal of the experimental analysis of behavior. 2022 05; 117(3):532-542. doi: 10.1002/jeab.756. [PMID: 35338651]
  • Sridhar Chinthakindi, Kurunthachalam Kannan. Urinary and fecal excretion of aromatic amines in pet dogs and cats from the United States. Environment international. 2022 05; 163(?):107208. doi: 10.1016/j.envint.2022.107208. [PMID: 35366557]
  • Ana L H Garcia, Cristina A Matzenbacher, Solange Soares, Paula Rohr, Juliana da Silva. Fluorosilicic acid and cotinine, separately and in combination, induce genotoxicity and telomeric reduction in human osteoblast cell line MG63. Mutation research. Genetic toxicology and environmental mutagenesis. 2022 Apr; 876-877(?):503474. doi: 10.1016/j.mrgentox.2022.503474. [PMID: 35483789]
  • T M Skipina, N Patel, B Upadhya, E Z Soliman. Secondhand smoke exposure is associated with abnormal P-wave axis. Public health. 2022 Apr; 205(?):79-82. doi: 10.1016/j.puhe.2022.01.026. [PMID: 35247863]
  • June Feng, Connie S Sosnoff, John T Bernert, Benjamin C Blount, Yao Li, Arseima Y Del Valle-Pinero, Heather L Kimmel, Dana M van Bemmel, Sharyn M Rutt, Juan Crespo-Barreto, Nicolette Borek, Kathryn C Edwards, Ricky Alexander, Stephen Arnstein, Charles Lawrence, Andrew Hyland, Maciej L Goniewicz, Imran Rehmani, Brittany Pine, Vincent Pagnotti, Erin Wade, James Sandlin, Zuzheng Luo, Sujeewa Piyankarage, Dorothy K Hatsukami, Stephen S Hecht, Kevin P Conway, Lanqing Wang. Urinary Nicotine Metabolites and Self-Reported Tobacco Use Among Adults in the Population Assessment of Tobacco and Health (PATH) Study, 2013-2014. Nicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco. 2022 03; 24(5):768-777. doi: 10.1093/ntr/ntab206. [PMID: 35348786]
  • Deepak Bhandari, Luyu Zhang, Wanzhe Zhu, Víctor R De Jesús, Benjamin C Blount. Optimal Cutoff Concentration of Urinary Cyanoethyl Mercapturic Acid for Differentiating Cigarette Smokers From Nonsmokers. Nicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco. 2022 03; 24(5):761-767. doi: 10.1093/ntr/ntab224. [PMID: 34718769]
  • Connie S Sosnoff, Kevin Caron, J Ricky Akins, Kristin Dortch, Ronald E Hunter, Brittany N Pine, June Feng, Benjamin C Blount, Yao Li, Dana M van Bemmel, Heather L Kimmel, Kathryn C Edwards, Maciej L Goniewicz, Dorothy K Hatsukami, B Rey de Castro, John T Bernert, Stephen Arnstein, Nicolette Borek, Ying Deng-Bryant, Elena Mishina, Charles Lawrence, Andrew Hyland, Stephen S Hecht, Kevin P Conway, James L Pirkle, Lanqing Wang. Serum Concentrations of Cotinine and Trans-3'-Hydroxycotinine in US Adults: Results From Wave 1 (2013-2014) of the Population Assessment of Tobacco and Health Study. Nicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco. 2022 03; 24(5):736-744. doi: 10.1093/ntr/ntab240. [PMID: 34897512]
  • Jiyeon Yang, Shervin Hashemi, Wonseok Han, Yoojin Song, Youngwook Lim. Exposure and Risk Assessment of Second- and Third-Hand Tobacco Smoke Using Urinary Cotinine Levels in South Korea. International journal of environmental research and public health. 2022 03; 19(6):. doi: 10.3390/ijerph19063746. [PMID: 35329433]
  • Shrila Mazumder, Winnie Shia, Patrick B Bendik, Honest Achilihu, Connie S Sosnoff, Joseph R Alexander, Zuzheng Luo, Wanzhe Zhu, Brittany N Pine, June Feng, Benjamin C Blount, Lanqing Wang. Nicotine Exposure in the U.S. Population: Total Urinary Nicotine Biomarkers in NHANES 2015-2016. International journal of environmental research and public health. 2022 03; 19(6):. doi: 10.3390/ijerph19063660. [PMID: 35329347]
  • Soo Hyeon Cho, Sung Hoon Jeong, Jaeyong Shin, Sohee Park, Sung-In Jang. Short-term smoking increases the risk of insulin resistance. Scientific reports. 2022 03; 12(1):3550. doi: 10.1038/s41598-022-07626-1. [PMID: 35241770]
  • Jeffrey S Wolf, John C Papadimitriou, Robert E Morales, Joseph A Califano, Neila L Kline, Kavita Bhatnagar, Andrea M Hebert, Rodney J Taylor. The association of active and passive tobacco smoke exposure with chronic rhinosinusitis symptom severity: A cross-sectional study. International forum of allergy & rhinology. 2022 03; 12(3):278-285. doi: 10.1002/alr.22887. [PMID: 34510792]
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  • Jan Hovanec, Tobias Weiß, Holger M Koch, Beate Pesch, Thomas Behrens, Benjamin Kendzia, Marina Arendt, Nico Dragano, Susanne Moebus, Börge Schmidt, Thomas Brüning, Karl-Heinz Jöckel. Smoking intensity and urinary nicotine metabolites by socioeconomic status in the Heinz Nixdorf Recall study. BMC public health. 2022 02; 22(1):302. doi: 10.1186/s12889-022-12609-y. [PMID: 35164711]
  • Jongwon Oh, Min-Seung Park, Mi-Ryung Chun, Jung Hye Hwang, Jin-Young Lee, Jae Hwan Jee, Soo-Youn Lee. A Simple and High-Throughput LC-MS-MS Method for Simultaneous Measurement of Nicotine, Cotinine, 3-OH Cotinine, Nornicotine and Anabasine in Urine and Its Application in the General Korean Population. Journal of analytical toxicology. 2022 Feb; 46(1):25-36. doi: 10.1093/jat/bkaa177. [PMID: 33231618]
  • Jacek Baj, Wojciech Flieger, Dominika Przygodzka, Grzegorz Buszewicz, Grzegorz Teresiński, Magdalena Pizoń, Ryszard Maciejewski, Jolanta Flieger. Application of HPLC-QQQ-MS/MS and New RP-HPLC-DAD System Utilizing the Chaotropic Effect for Determination of Nicotine and Its Major Metabolites Cotinine, and trans-3'-Hydroxycotinine in Human Plasma Samples. Molecules (Basel, Switzerland). 2022 Jan; 27(3):. doi: 10.3390/molecules27030682. [PMID: 35163947]
  • Joshua J H Hunsaker, Sonia L La'ulu, Danielle LaGrave, Wendy Murphy, Heather A Reichman, Taylor M Snow, Gwendolyn A McMillin, Kamisha L Johnson-Davis, Jonathan R Genzen. Tobacco and Cannabis Use During Pregnancy. American journal of clinical pathology. 2022 Jan; 157(1):146-152. doi: 10.1093/ajcp/aqab093. [PMID: 34508553]
  • Kerti Ausmees, Nele Reimets, Indrek Reile. Parahydrogen hyperpolarization of minimally altered urine samples for sensitivity enhanced NMR metabolomics. Chemical communications (Cambridge, England). 2022 Jan; 58(3):463-466. doi: 10.1039/d1cc05665d. [PMID: 34908034]
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  • Jaclyn Parks, Kathleen E McLean, Lawrence McCandless, Russell J de Souza, Jeffrey R Brook, James Scott, Stuart E Turvey, Piush J Mandhane, Allan B Becker, Meghan B Azad, Theo J Moraes, Diana L Lefebvre, Malcolm R Sears, Padmaja Subbarao, Tim K Takaro. Assessing secondhand and thirdhand tobacco smoke exposure in Canadian infants using questionnaires, biomarkers, and machine learning. Journal of exposure science & environmental epidemiology. 2022 01; 32(1):112-123. doi: 10.1038/s41370-021-00350-4. [PMID: 34175887]
  • Youran Tan, Dana Boyd Barr, P Barry Ryan, Veronika Fedirko, Jeremy A Sarnat, Audrey J Gaskins, Che-Jung Chang, Ziyin Tang, Carmen J Marsit, Elizabeth J Corwin, Dean P Jones, Anne L Dunlop, Donghai Liang. High-resolution metabolomics of exposure to tobacco smoke during pregnancy and adverse birth outcomes in the Atlanta African American maternal-child cohort. Environmental pollution (Barking, Essex : 1987). 2022 Jan; 292(Pt A):118361. doi: 10.1016/j.envpol.2021.118361. [PMID: 34655695]
  • Cassandra C Derella, Martha S Tingen, Anson Blanks, Samantha J Sojourner, Matthew A Tucker, Jeffrey Thomas, Ryan A Harris. Smoking cessation reduces systemic inflammation and circulating endothelin-1. Scientific reports. 2021 12; 11(1):24122. doi: 10.1038/s41598-021-03476-5. [PMID: 34916543]
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