2U2U884D0P (BioDeep_00000230000)

Main id: BioDeep_00000227066

 

PANOMIX_OTCML-2023


Metabolite Card


4H-1-Benzopyran-4-one, 5,7,8-trimethoxy-2-(4-methoxyphenyl)-

Formula: C19H18O6 (342.1103)
Chinese Names: 4,5,7,8-四甲氧基黄酮, 6-去甲氧基三苯甲基黄嘌呤, 6-去甲氧基桔皮素, 6-去甲氧基坦格瑞汀
Spectrum Hits: Top Source () 0%

Molecular Structure

SMILES: C12C(=O)C=C(C3C=CC(OC)=CC=3)OC=1C(OC)=C(OC)C=C2OC
InChI: InChI=1S/C19H18O6/c1-21-12-7-5-11(6-8-12)14-9-13(20)17-15(22-2)10-16(23-3)18(24-4)19(17)25-14/h5-10H,1-4H3

Description

6-Demethoxytangeretin is a natural product found in Juncus effusus, Neoraputia alba, and other organisms with data available.
See also: Tangerine peel (part of); Citrus aurantium fruit rind (part of).
6-Demethoxytangeretin is a citrus flavonoid isolated from Citrus reticulata. 6-Demethoxytangeretin exerts anti-inflammatory activity and anti-allergic activity, suppresses production and gene expression of interleukin-6 in human mast cell-1 via anaplastic lymphoma kinase (ALK) and mitogen-activated protein kinase (MAPK) pathways[1]. 6-Demethoxytangeretin facilitates the CRE-mediated transcription associated with learning and memory in cultured hippocampal neurons[2].
6-Demethoxytangeretin is a citrus flavonoid isolated from Citrus reticulata. 6-Demethoxytangeretin exerts anti-inflammatory activity and anti-allergic activity, suppresses production and gene expression of interleukin-6 in human mast cell-1 via anaplastic lymphoma kinase (ALK) and mitogen-activated protein kinase (MAPK) pathways[1]. 6-Demethoxytangeretin facilitates the CRE-mediated transcription associated with learning and memory in cultured hippocampal neurons[2].

Synonyms

15 synonym names

4H-1-Benzopyran-4-one, 5,7,8-trimethoxy-2-(4-methoxyphenyl)-; 5,7,8-Trimethoxy-2-(4-methoxyphenyl)-4H-chromen-4-one #; 5,7,8-Trimethoxy-2-(4-methoxyphenyl)-4H-chromen-4-one; 5,7,8-trimethoxy-2-(4-methoxyphenyl)chromen-4-one; Tetra-O-methylisoscutellarein; 5,7,8,4-TETRAMETHOXYFLAVONE; 5,7,8,4-tetramethoxyflavone; 4,5,7,8-Tetramethoxyflavone; DDGJUTBQQURRGE-UHFFFAOYSA-N; Tetramethylisoscutellarein; 6-Demethoxytangeritin; 6-Demethoxytangeretin; UNII-2U2U884D0P; 2U2U884D0P; 6-Demethoxytangeretin



Cross Reference

8 cross reference id

Classification Terms

Related Pathways

Reactome(0)

BioCyc(0)

PlantCyc(0)

Biological Process

0 related biological process reactions.

Reactome(0)

BioCyc(0)

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Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

3 organism taxonomy source information

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：

  • PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。



Literature Reference

  • Stephen S Nyandoro, Joan J E Munissi, Amra Gruhonjic, Sandra Duffy, Fangfang Pan, Rakesh Puttreddy, John P Holleran, Paul A Fitzpatrick, Jerry Pelletier, Vicky M Avery, Kari Rissanen, Máté Erdélyi. Polyoxygenated Cyclohexenes and Other Constituents of Cleistochlamys kirkii Leaves. Journal of natural products. 2017 01; 80(1):114-125. doi: 10.1021/acs.jnatprod.6b00759. [PMID: 28001067]
  • D Thinès-Sempoux, M Wibo, A Amar-Costesec, H Beaufay. Enzymatic and morphological heterogeneity of rat plasma membranes [proceedings]. Archives internationales de physiologie et de biochimie. 1978 Oct; 86(4):889-90. doi: NULL. [PMID: 84599]