8-Hydroxydaidzein (BioDeep_00000020036)

 

Secondary id: BioDeep_00000270781, BioDeep_00000863322, BioDeep_00001874152

human metabolite PANOMIX_OTCML-2023 natural product


代谢物信息卡片


7,8-Dihydroxy-3-(4-hydroxyphenyl)-4H-1-benzopyran-4-one, 9ci

化学式: C15H10O5 (270.052821)
中文名称: 7,8-二羟基-3-(4-羟基苯基)苯并吡喃-4-酮
谱图信息: 最多检出来源 Chinese Herbal Medicine(otcml) 8.57%

分子结构信息

SMILES: c1(ccc2c(c1O)occ(c2=O)c1ccc(cc1)O)O
InChI: InChI=1S/C15H10O5/c16-9-3-1-8(2-4-9)11-7-20-15-10(13(11)18)5-6-12(17)14(15)19/h1-7,16-17,19H

描述信息

8-Hydroxydaidzein is found in pulses. 8-Hydroxydaidzein is isolated from Streptomyces sp. OH-1049 cultured on soybean meal.
Isolated from Streptomyces species OH-1049 cultured on soybean meal. 8-Hydroxydaidzein is found in soy bean and pulses.

同义名列表

11 个代谢物同义名

7,8-Dihydroxy-3-(4-hydroxyphenyl)-4H-1-benzopyran-4-one, 9ci; 7,8-Dihydroxy-3-(4-hydroxyphenyl)-4H-1-benzopyran-4-one; 7,8-Dihydroxy-3-(4-hydroxyphenyl)-4H-chromen-4-one; 7,8-Dihydroxy-3-(4-hydroxy-phenyl)-chromen-4-one; 7,8-Dihydroxy-3-(4-hydroxyphenyl)chromen-4-one; 4,7,8-Trihydroxyisoflavone; 7,8,4-Trihydroxyisoflavone; 784-Trihydroxyisoflavone; 478-Trihydroxyisoflavone; 8-Hydroxydaidzein; NSC 678112



数据库引用编号

10 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(0)

BioCyc(0)

PlantCyc(0)

代谢反应

0 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

27 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：

  • PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。



文献列表

  • Irena Baranowska, Sylwia Magiera, Jacek Baranowski. UHPLC method for the simultaneous determination of β-blockers, isoflavones and their metabolites in human urine. Journal of chromatography. B, Analytical technologies in the biomedical and life sciences. 2011 Mar; 879(9-10):615-26. doi: 10.1016/j.jchromb.2011.01.026. [PMID: 21345747]
  • Chia-Hsiang Victor Lin, Hsiou-Yu Ding, Shiou-Yi Kuo, Ling-Wei Chin, Jiumn-Yih Wu, Te-Sheng Chang. Evaluation of in vitro and in vivo depigmenting activity of raspberry ketone from Rheum officinale. International journal of molecular sciences. 2011; 12(8):4819-35. doi: 10.3390/ijms12084819. [PMID: 21954327]
  • Jun-Seong Park, Dong Hyun Kim, Jae Kyoung Lee, Jin Young Lee, Duck Hee Kim, Han Kon Kim, Hak-Ju Lee, Ho Cheol Kim. Natural ortho-dihydroxyisoflavone derivatives from aged Korean fermented soybean paste as potent tyrosinase and melanin formation inhibitors. Bioorganic & medicinal chemistry letters. 2010 Feb; 20(3):1162-4. doi: 10.1016/j.bmcl.2009.12.021. [PMID: 20022495]
  • Gui-Ping Zhang, Zhi-Yong Xiao, Jamal Rafique, Mohammad Arfan, Peter J Smith, Carmen A Lategan, Li-Hong Hu. Antiplasmodial isoflavanones from the roots of Sophora mollis. Journal of natural products. 2009 Jul; 72(7):1265-8. doi: 10.1021/np900144c. [PMID: 19572738]
  • Tammy E Hedlund, Adrie van Bokhoven, Widya U Johannes, Steven K Nordeen, Lorraine G Ogden. Prostatic fluid concentrations of isoflavonoids in soy consumers are sufficient to inhibit growth of benign and malignant prostatic epithelial cells in vitro. The Prostate. 2006 Apr; 66(5):557-66. doi: 10.1002/pros.20380. [PMID: 16372328]
  • Hideo Esaki, Tomomi Shirasaki, Kanae Yamashita, Yoshiyuki Nakamura, Shunro Kawakishi, Toshihiko Osawa. Absorption and excretion of the 8-hydroxydaidzein in rats after oral administration and its antioxidant effect. Journal of nutritional science and vitaminology. 2005 Apr; 51(2):80-6. doi: 10.3177/jnsv.51.80. [PMID: 16022193]
  • S E Kulling, D M Honig, M Metzler. Oxidative metabolism of the soy isoflavones daidzein and genistein in humans in vitro and in vivo. Journal of agricultural and food chemistry. 2001 Jun; 49(6):3024-33. doi: 10.1021/jf0012695. [PMID: 11410004]