Isoacteoside (BioDeep_00000018879)

Main id: BioDeep_00000230510

 

human metabolite PANOMIX_OTCML-2023 natural product


代谢物信息卡片


{6-[2-(3,4-dihydroxyphenyl)ethoxy]-3,5-dihydroxy-4-[(3,4,5-trihydroxy-6-methyloxan-2-yl)oxy]oxan-2-yl}methyl (2E)-3-(3,4-dihydroxyphenyl)prop-2-enoic acid

化学式: C29H36O15 (624.2054106)
中文名称: 异麦角甾苷
谱图信息: 最多检出来源 () 0%

分子结构信息

SMILES: CC1C(C(C(C(O1)OC2C(C(OC(C2O)OCCC3=CC(=C(C=C3)O)O)COC(=O)C=CC4=CC(=C(C=C4)O)O)O)O)O)O
InChI: InChI=1S/C29H36O15/c1-13-22(35)24(37)25(38)29(42-13)44-27-23(36)20(12-41-21(34)7-4-14-2-5-16(30)18(32)10-14)43-28(26(27)39)40-9-8-15-3-6-17(31)19(33)11-15/h2-7,10-11,13,20,22-33,35-39H,8-9,12H2,1H3/b7-4+

描述信息

Isoacteoside is a polyphenol compound found in foods of plant origin (PMID: 20428313).
A polyphenol compound found in foods of plant origin (PhenolExplorer)
Isoacteoside is a natural product that can significantly inhibit the formation of glycation end products.
Isoacteoside is a natural product that can significantly inhibit the formation of glycation end products.

同义名列表

6 个代谢物同义名

{6-[2-(3,4-dihydroxyphenyl)ethoxy]-3,5-dihydroxy-4-[(3,4,5-trihydroxy-6-methyloxan-2-yl)oxy]oxan-2-yl}methyl (2E)-3-(3,4-dihydroxyphenyl)prop-2-enoic acid; {6-[2-(3,4-dihydroxyphenyl)ethoxy]-3,5-dihydroxy-4-[(3,4,5-trihydroxy-6-methyloxan-2-yl)oxy]oxan-2-yl}methyl (2E)-3-(3,4-dihydroxyphenyl)prop-2-enoate; [6-[2-(3,4-dihydroxyphenyl)ethoxy]-3,5-dihydroxy-4-(3,4,5-trihydroxy-6-methyloxan-2-yl)oxyoxan-2-yl]methyl (E)-3-(3,4-dihydroxyphenyl)prop-2-enoate; isoverbascoside; Isoacteoside; isoacetoside



数据库引用编号

9 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(0)

BioCyc(0)

PlantCyc(0)

代谢反应

0 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

182 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：

  • PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。



文献列表

  • Mario Bernardi, Mohammad Reza Ghaani, Omer Bayazeid. Phenylethanoid glycosides as a possible COVID-19 protease inhibitor: a virtual screening approach. Journal of molecular modeling. 2021 Nov; 27(11):341. doi: 10.1007/s00894-021-04963-2. [PMID: 34731296]
  • Bin Wang, Xi-Han Li, Zhang Song, Min-Li Li, Xiao-Wei Wu, Mei-Xia Guo, Xiao-Hua Zhang, Xiao-Ping Zou. Isoacteoside attenuates acute kidney injury induced by severe acute pancreatitis. Molecular medicine reports. 2021 04; 23(4):. doi: 10.3892/mmr.2021.11926. [PMID: 33649800]
  • Son Tung Ngo, Ngoc Quynh Anh Pham, Ly Thi Le, Duc-Hung Pham, Van V Vu. Computational Determination of Potential Inhibitors of SARS-CoV-2 Main Protease. Journal of chemical information and modeling. 2020 12; 60(12):5771-5780. doi: 10.1021/acs.jcim.0c00491. [PMID: 32530282]
  • Mengqi Zhang, Xia Ren, Shijun Yue, Qing Zhao, Changlun Shao, Changyun Wang. Simultaneous Quantification of Four Phenylethanoid Glycosides in Rat Plasma by UPLC-MS/MS and Its Application to a Pharmacokinetic Study of Acanthus Ilicifolius Herb. Molecules (Basel, Switzerland). 2019 Aug; 24(17):. doi: 10.3390/molecules24173117. [PMID: 31466218]
  • Bingwei Feng, Yonggui Song, Qiongming Xu, Pengfei Xu, Qiang Zeng, Baixi Shan, Kuangyi Liu, Dan Su. Simultaneous determination of savaside A, acteoside, and isoacteoside in rat plasma by UHPLC-MS/MS: Comparative pharmacokinetic and bioavailability characteristics of Monochasma savatieri via different routes of administration. Journal of separation science. 2018 Dec; 41(24):4408-4418. doi: 10.1002/jssc.201800545. [PMID: 30307101]
  • Hongwei Gao, Yankun Cui, Naixin Kang, Xin Liu, Yanli Liu, Yue Zou, Ziyu Zhang, Xiaoran Li, Shilin Yang, Ji Li, Chunming Wang, Qiong-Ming Xu, Xiuping Chen. Isoacteoside, a dihydroxyphenylethyl glycoside, exhibits anti-inflammatory effects through blocking toll-like receptor 4 dimerization. British journal of pharmacology. 2017 Sep; 174(17):2880-2896. doi: 10.1111/bph.13912. [PMID: 28616865]
  • Qingling Cui, Yingni Pan, Xiaowei Yan, Bao Qu, Xiaoqiu Liu, Wei Xiao. A metabolic way to investigate related hurdles causing poor bioavailability in oral delivery of isoacteoside in rats employing ultrahigh-performance liquid chromatography/quadrupole time-of-flight tandem mass spectrometry. Rapid communications in mass spectrometry : RCM. 2017 Feb; 31(4):371-380. doi: 10.1002/rcm.7795. [PMID: 27859774]
  • Dan Su, Wei Li, Qiongming Xu, Yali Liu, Yonggui Song, Yulin Feng. New metabolites of acteoside identified by ultra-performance liquid chromatography/quadrupole-time-of-flight MS(E) in rat plasma, urine, and feces. Fitoterapia. 2016 Jul; 112(?):45-55. doi: 10.1016/j.fitote.2016.05.004. [PMID: 27223850]
  • Mbaki Muzila, Kimmo Rumpunen, Helen Wright, Helen Roberts, Melissa Grant, Hilde Nybom, Jasna Sehic, Anders Ekholm, Cecilia Widén. Alteration of Neutrophil Reactive Oxygen Species Production by Extracts of Devil's Claw (Harpagophytum). Oxidative medicine and cellular longevity. 2016; 2016(?):3841803. doi: 10.1155/2016/3841803. [PMID: 27429708]
  • Jun Zhou, Qiong Zhang, Jiang Bing Sun, Xiao Li Sun, Ping Zeng. Two-phase hollow fiber liquid phase microextraction based on magnetofluid for simultaneous determination of Echinacoside, Tubuloside B, Acteoside and Isoacteoside in rat plasma after oral administration of Cistanche salsa extract by high performance liquid chromatography. Journal of pharmaceutical and biomedical analysis. 2014 Jun; 94(?):30-5. doi: 10.1016/j.jpba.2014.01.013. [PMID: 24531006]
  • Gianina Crişan, M Tămaş, V Miclăuş, T Krausz, Vl Sandor. A comparative study of some Veronica species. Revista medico-chirurgicala a Societatii de Medici si Naturalisti din Iasi. 2007 Jan; 111(1):280-4. doi: NULL. [PMID: 17595882]