RIOPROSTIL (BioDeep_00000182955)
human metabolite blood metabolite
代谢物信息卡片
化学式: C21H38O4 (354.277)
中文名称:
谱图信息:
最多检出来源 Homo sapiens(blood) 100%
分子结构信息
SMILES: CCCCC(C)(O)CC=CC1C(O)CC(=O)C1CCCCCCCO
InChI: InChI=1S/C21H38O4/c1-3-4-13-21(2,25)14-10-12-18-17(19(23)16-20(18)24)11-8-6-5-7-9-15-22/h10,12,17-18,20,22,24-25H,3-9,11,13-16H2,1-2H3
描述信息
同义名列表
相关代谢途径
Reactome(0)
BioCyc(0)
PlantCyc(0)
代谢反应
0 个相关的代谢反应过程信息。
Reactome(0)
BioCyc(0)
WikiPathways(0)
Plant Reactome(0)
INOH(0)
PlantCyc(0)
COVID-19 Disease Map(0)
PathBank(0)
PharmGKB(0)
1 个相关的物种来源信息
在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：
- PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
- NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
- Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
- Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。
点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。
| 亚细胞结构定位 | 关联基因列表 |
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文献列表
- U Metz-Kurschel, K Wagner, M K Mueller. The synthetic prostaglandin E1 analogue rioprostil reduces the nephrotoxic potential of cyclosporine A.
Transplantation proceedings.
1990 Aug; 22(4):1713-6. doi:
NULL. [PMID: 1975139] - O Segers, G Somers. Effect of rioprostil, a methylprostaglandin E1 analog, on basal and stimulated plasma pancreatic hormone levels in man.
Digestive diseases and sciences.
1990 Jan; 35(1):20-6. doi:
10.1007/bf01537217. [PMID: 2104796] - H H Thijssen, K Hamulyàk. The interaction of the prostaglandin E derivative rioprostil with oral anticoagulant agents.
Clinical pharmacology and therapeutics.
1989 Jul; 46(1):110-6. doi:
10.1038/clpt.1989.114. [PMID: 2501056] - H G Eichler, A Korn, J A Businger, W K Waldhäusl. Rioprostil, a new prostaglandin E1 analogue does not affect glucose homeostasis in healthy volunteers.
Archives internationales de pharmacodynamie et de therapie.
1989 Mar; 298(?):288-92. doi:
NULL. [PMID: 2502955] - D de Lauture, E Rey, P d'Athis, M O Richard, D Paccaly, F Prunieras, G Strauch, G Olive. Pharmacokinetic interactions between theophylline and rioprostil.
Scandinavian journal of gastroenterology. Supplement.
1989; 164(?):63-6; discussion 67. doi:
10.3109/00365528909091189. [PMID: 2510283] - S Fischer, H Schweer, H Kraft, P Weber. Pharmacokinetics of rioprostil in human plasma as assayed by combined capillary gas chromatography-negative ion chemical ionization mass spectrometry.
Scandinavian journal of gastroenterology. Supplement.
1989; 164(?):59-61; discussion 61. doi:
10.3109/00365528909091188. [PMID: 2510282] - P Demol, W Wingender, J Kuhlmann. Effect of rioprostil, a methyl-prostaglandin E1, on plasma level and renal excretion of beta-acetyldigoxin.
Scandinavian journal of gastroenterology. Supplement.
1989; 164(?):68-71; discussion 71. doi:
NULL. [PMID: 2510284] - V Vlahov, V Kirkov, P Popov, Z Gerova. Protective effect of rioprostil on indomethacin-induced lesions of gastric and duodenal mucosa in healthy volunteers.
Scandinavian journal of gastroenterology. Supplement.
1989; 164(?):169-73. doi:
10.3109/00365528909091207. [PMID: 2510262] - J K Petersen-von Gehr, H M Siefert, W Steinke. Pharmacokinetics of rioprostil in rats.
Scandinavian journal of gastroenterology. Supplement.
1989; 164(?):46-50; discussion 50. doi:
10.3109/00365528909091185. [PMID: 2510280] - H Koop, H Schwarting, U Eckel, J Wagenknecht, U Hallfeldt, R Arnold. Influence of chronic rioprostil treatment on gastric endocrine function.
Scandinavian journal of gastroenterology. Supplement.
1989; 164(?):104-10; discussion 110. doi:
10.3109/00365528909091196. [PMID: 2573147] - H J Ahr, W Karl, D Scherling, C Wünsche. Metabolic fate of rioprostil in the rat--in vivo and in liver perfusion.
Scandinavian journal of gastroenterology. Supplement.
1989; 164(?):52-7. doi:
10.3109/00365528909091186. [PMID: 2510281] - I Bjarnason, P Smethurst, P Clark, I Menzies, J Levi, T Peters. Effect of prostaglandin on indomethacin-induced increased intestinal permeability in man.
Scandinavian journal of gastroenterology. Supplement.
1989; 164(?):97-102; discussion 102. doi:
10.3109/00365528909091195. [PMID: 2510288] - M K Müller, H Degenhardt, G Klöppel, H Goebell, K Bergmann, M Löhr. Prevention of toxic effects of cyclosporin on pancreatic B-cells of rats by Rioprostil, a new prostaglandin analogue.
Gut.
1988 Nov; 29(11):1524-30. doi:
10.1136/gut.29.11.1524. [PMID: 3145244] - L B Katz, T Genna, G H Greeley, D A Shriver. Antisecretory and antigastrin effects of rioprostil in gastric fistula dogs.
Digestive diseases and sciences.
1987 Nov; 32(11):1268-74. doi:
10.1007/bf01296377. [PMID: 3117511] - M Mourelle, J L Amezcua, E Hong. Effect of rioprostil and colchicine on CCl4-acute liver damage in rats. Relationship with plasma membrane lipids.
Prostaglandins.
1987 Jun; 33(6):869-77. doi:
10.1016/0090-6980(87)90115-8. [PMID: 2890182] - K Schulte, M V Singer, V Eysselein, P Demol, H Goebell. Effect of rioprostil, a synthetic prostaglandin E1 on meal-stimulated gastric acid secretion and plasma gastrin levels in humans.
Digestion.
1987; 36(3):162-7. doi:
10.1159/000199413. [PMID: 3109990] - B Simon, H G Dammann, P Müller. Prostaglandins and peptic ulcer disease: nocturnal administration of rioprostil vs ranitidine in duodenal ulcer healing.
Klinische Wochenschrift.
1986; 64 Suppl 7(?):44-6. doi:
NULL. [PMID: 3104657]
