4-[3,4,5-Trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxybenzaldehyde (BioDeep_00000179692)

   

human metabolite blood metabolite natural product


代谢物信息卡片


4-{[3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy}benzaldehyde

化学式: C13H16O7 (284.0895986)
中文名称:
谱图信息: 最多检出来源 () 0%

分子结构信息

SMILES: C1=CC(=CC=C1C=O)OC2C(C(C(C(O2)CO)O)O)O
InChI: InChI=1S/C13H16O7/c14-5-7-1-3-8(4-2-7)19-13-12(18)11(17)10(16)9(6-15)20-13/h1-5,9-13,15-18H,6H2

描述信息

同义名列表

3 个代谢物同义名

4-{[3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy}benzaldehyde; 4-[3,4,5-Trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxybenzaldehyde; Helicide



数据库引用编号

5 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(0)

BioCyc(0)

PlantCyc(0)

代谢反应

0 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

22 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：

  • PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。



文献列表

  • Yuan-Xiang Zhang, Xiao-Tong Zhang, Hong-Jin Li, Tao-Feng Zhou, An-Cheng Zhou, Zheng-Ling Zhong, Yan-Hao Liu, Li-Li Yuan, Hao-Yu Zhu, Di Luan, Jiu-Cui Tong. Antidepressant-like effects of helicid on a chronic unpredictable mild stress-induced depression rat model: Inhibiting the IKK/IκBα/NF-κB pathway through NCALD to reduce inflammation. International immunopharmacology. 2021 Apr; 93(?):107165. doi: 10.1016/j.intimp.2020.107165. [PMID: 33578182]
  • Jiucui Tong, Zhiming Zhou, Weiwei Qi, Siyan Jiang, Bin Yang, Zhengling Zhong, Yuanwei Jia, Xuyi Li, Lei Xiong, Liuwang Nie. Antidepressant effect of helicid in chronic unpredictable mild stress model in rats. International immunopharmacology. 2019 Feb; 67(?):13-21. doi: 10.1016/j.intimp.2018.11.052. [PMID: 30530165]
  • Manjunath D Meti, Yang Xu, Jiangfeng Xie, Yutao Chen, Zhibing Wu, Johnson Liu, Qingguo Han, Zhendan He, Zhangli Hu, Hong Xu. Multi-spectroscopic studies on the interaction between traditional Chinese herb, helicid with pepsin. Molecular biology reports. 2018 Dec; 45(6):1637-1646. doi: 10.1007/s11033-018-4306-5. [PMID: 30215193]
  • Yuanwei Jia, Jie Shen, Jianguo Sun, Wei Wang, Haitang Xie. Bioavailability and pharmacokinetics profile of helicid in beagle dogs using gradient elution high performance liquid chromatography electrospray ionization mass spectrometry. Journal of chromatography. B, Analytical technologies in the biomedical and life sciences. 2015 Apr; 988(?):8-12. doi: 10.1016/j.jchromb.2015.02.003. [PMID: 25743699]
  • Yuanyuan Yue, Jianming Liu, Ren Liu, Qiao Dong, Jing Fan. Binding of helicid to human serum albumin: a hybrid spectroscopic approach and conformational study. Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy. 2014 Apr; 124(?):46-51. doi: 10.1016/j.saa.2013.12.108. [PMID: 24463239]
  • Haitang Xie, Yuanwei Jia, Zhirong Tan, Wei Zhang, Rao Chen, Hua Sun, Jie Shen, Honghao Zhou. LC-MS/MS determination of helicid in human plasma and its application in pharmacokinetic studies. Journal of chromatography. B, Analytical technologies in the biomedical and life sciences. 2011 Nov; 879(30):3607-11. doi: 10.1016/j.jchromb.2011.10.001. [PMID: 22024391]
  • Yuanwei Jia, Haitang Xie, Guangji Wang, Jianguo Sun, Wei Wang, Huang Qing, Xuan Wang, Hao Yang, Meijuan Xu, Yi Gu, Chen Yao, Jie Shen. Quantitative determination of helicid in rat biosamples by liquid chromatography electrospray ionization mass spectrometry. Journal of chromatography. B, Analytical technologies in the biomedical and life sciences. 2010 Mar; 878(9-10):791-7. doi: 10.1016/j.jchromb.2010.01.038. [PMID: 20176516]
  • Zhuo Chen, Xue-hua Jiang, Jing Ren, Tai-ming Liu, Guo Ma, Ling Wang. [Investigation on pharmacokinetics of helicid in rats]. Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica. 2008 Nov; 33(22):2662-6. doi: NULL. [PMID: 19216167]
  • Yuanwei Jia, Guangji Wang, Haitang Xie, Xiaochang Dai, Yanhua Wang, Wei Wang, Meijuan Xu, Rui Wang, Chen Yao. Quantitative determination of helicid in rat plasma by liquid chromatography-electrospray ionization mass spectrometry and its application to preliminary pharmacokinetic studies. Journal of chromatography. B, Analytical technologies in the biomedical and life sciences. 2007 Mar; 847(2):72-7. doi: 10.1016/j.jchromb.2006.09.020. [PMID: 17046341]
  • Gui-Yan Liu, Shuang-Cheng, Yu-Mei Zhang, Ji-Min Xu, Rui-Chao Lin. [Study on chemical constituents in seeds of Helicia nilagirica (II)]. Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica. 2005 Jun; 30(11):830-2. doi: ". [PMID: 16110863]