But-2-enedioic acid (BioDeep_00000176880)

   

human metabolite blood metabolite natural product


代谢物信息卡片


but-2-enedioic acid

  化学式: C4H4O4 (116.011)
中文名称:
  谱图信息: 最多检出来源 Homo sapiens(blood) 8.08%

分子结构信息

SMILES: O=C(O)C=CC(=O)O
InChI: InChI=1S/C4H4O4/c5-3(6)1-2-4(7)8/h1-2H,(H,5,6)(H,7,8)


描述信息

同义名列表

6 个代谢物同义名

But-2-enedioic acid; 2-Butenedioic acid; Butenedioic acid; But-2-enedioate; 2-Butenedioate; Butenedioate



数据库引用编号

5 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome()

BioCyc()

PlantCyc()

代谢反应

个相关的代谢反应过程信息。

Reactome()

BioCyc()

WikiPathways()

Plant Reactome()

INOH()

PlantCyc()

COVID-19 Disease Map()

PathBank()

PharmGKB()

100 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：

  • PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。

亚细胞结构定位 关联基因列表


文献列表

  • Antika Boondaeng, Jureeporn Keabpimai, Chanaporn Trakunjae, Nanthavut Niyomvong. Fumaric acid production from fermented oil palm empty fruit bunches using fungal isolate K20: a comparison between free and immobilized cells. PeerJ. 2024; 12(?):e17282. doi: 10.7717/peerj.17282. [PMID: 38666083]
  • Tantan Gao, Xudong Wang, Yanqiu Qin, Zhengguang Ren, Xiaoyan Zhao. Watermelon Root Exudates Enhance Root Colonization of Bacillus amyloliquefaciens TR2. Current microbiology. 2023 Feb; 80(4):110. doi: 10.1007/s00284-023-03206-2. [PMID: 36802037]
  • Fei Sun, Xiang-Qin Wu, Yue Qi, Xing-Yu Chen, Yu-Hua Cao, Jian-Gang Wang, Shu-Mei Wang, Sheng-Wang Liang. [Application of partial least squares algorithm to explore bioactive components of crude and stir-baked hawthorn for invigorating spleen and promoting digestion]. Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica. 2023 Feb; 48(4):958-965. doi: 10.19540/j.cnki.cjcmm.20220712.302. [PMID: 36872266]
  • Anjali Zaveri, Jacqueline Edwards, Simone Rochfort. Production of Primary Metabolites by Rhizopus stolonifer, Causal Agent of Almond Hull Rot Disease. Molecules (Basel, Switzerland). 2022 Oct; 27(21):. doi: 10.3390/molecules27217199. [PMID: 36364023]
  • Aysegul Eroglu, Abdulahad Dogan. Investigation of the phytochemical composition and remedial effects of southern grape hyacinth (Muscari neglectum Guss. ex Ten.) plant extract against carbon tetrachloride-induced oxidative stress in rats. Drug and chemical toxicology. 2022 Apr; ?(?):1-12. doi: 10.1080/01480545.2022.2058011. [PMID: 35373681]
  • Sengnolotha Marak, Elena Shumilina, Nutan Kaushik, Eva Falch, Alexander Dikiy. Effect of Different Drying Methods on the Nutritional Value of Hibiscus sabdariffa Calyces as Revealed by NMR Metabolomics. Molecules (Basel, Switzerland). 2021 Mar; 26(6):. doi: 10.3390/molecules26061675. [PMID: 33802805]
  • Wioletta Siemiradzka, Barbara Dolińska, Florian Ryszka. Preparation of Sterile Raw Material - Chicken Eggshells in the Process of their Transformation into Selected Calcium Salts. Current pharmaceutical biotechnology. 2021; 22(2):299-304. doi: 10.2174/1389201021666200903120835. [PMID: 32881665]
  • Syed Ilias Basha, Somnath Ghosh, K Vinothkumar, B Ramesh, P Hema Praksh Kumari, K V Murali Mohan, E Sukumar. Fumaric acid incorporated Ag/agar-agar hybrid hydrogel: A multifunctional avenue to tackle wound healing. Materials science & engineering. C, Materials for biological applications. 2020 Jun; 111(?):110743. doi: 10.1016/j.msec.2020.110743. [PMID: 32279739]
  • Forouzan Heidari, Abbas Bahari, Ali Amarlou, Barat Ali Fakheri. Fumaric acids as a novel antagonist of TLR-4 pathway mitigates arsenic-exposed inflammation in human monocyte-derived dendritic cells. Immunopharmacology and immunotoxicology. 2019 Aug; 41(4):513-520. doi: 10.1080/08923973.2019.1645166. [PMID: 31397191]
  • Zong Xian Zhu, Dan Li Jiang, Bi Jun Li, Hui Qin, Zi Ning Meng, Hao Ran Lin, Jun Hong Xia. Differential Transcriptomic and Metabolomic Responses in the Liver of Nile Tilapia (Oreochromis niloticus) Exposed to Acute Ammonia. Marine biotechnology (New York, N.Y.). 2019 Aug; 21(4):488-502. doi: 10.1007/s10126-019-09897-8. [PMID: 31076921]
  • Guangyuan Wang, Tingting Bai, Zhengang Miao, Weiguang Ning, Wenxing Liang. Simultaneous production of single cell oil and fumaric acid by a newly isolated yeast Aureobasidium pullulans var. aubasidani DH177. Bioprocess and biosystems engineering. 2018 Nov; 41(11):1707-1716. doi: 10.1007/s00449-018-1994-0. [PMID: 30069713]
  • Juan P Zubimendi, Andrea Martinatto, Maria P Valacco, Silvia Moreno, Carlos S Andreo, María F Drincovich, Marcos A Tronconi. The complex allosteric and redox regulation of the fumarate hydratase and malate dehydratase reactions of Arabidopsis thaliana Fumarase 1 and 2 gives clues for understanding the massive accumulation of fumarate. The FEBS journal. 2018 06; 285(12):2205-2224. doi: 10.1111/febs.14483. [PMID: 29688630]
  • Shatrupa Ray, Sandhya Mishra, Kartikay Bisen, Surendra Singh, Birinchi Kumar Sarma, Harikesh Bahadur Singh. Modulation in phenolic root exudate profile of Abelmoschus esculentus expressing activation of defense pathway. Microbiological research. 2018 Mar; 207(?):100-107. doi: 10.1016/j.micres.2017.11.011. [PMID: 29458844]
  • Xin Li, Jin Zhou, Shuiping Ouyang, Jia Ouyang, Qiang Yong. Fumaric Acid Production from Alkali-Pretreated Corncob by Fed-Batch Simultaneous Saccharification and Fermentation Combined with Separated Hydrolysis and Fermentation at High Solids Loading. Applied biochemistry and biotechnology. 2017 Feb; 181(2):573-583. doi: 10.1007/s12010-016-2232-3. [PMID: 27604834]
  • Marcos Hernández Suárez, Daniel Molina Pérez, Elena M Rodríguez-Rodríguez, Carlos Díaz Romero, Francisco Espinosa Borreguero, Purificación Galindo-Villardón. The Compositional HJ-Biplot-A New Approach to Identifying the Links among Bioactive Compounds of Tomatoes. International journal of molecular sciences. 2016 Nov; 17(11):. doi: 10.3390/ijms17111828. [PMID: 27827839]
  • M M Montiel-Rozas, E Madejón, P Madejón. Effect of heavy metals and organic matter on root exudates (low molecular weight organic acids) of herbaceous species: An assessment in sand and soil conditions under different levels of contamination. Environmental pollution (Barking, Essex : 1987). 2016 Sep; 216(?):273-281. doi: 10.1016/j.envpol.2016.05.080. [PMID: 27267743]
  • Dong Wuk Kim, Young Hun Kim, Abid Mehmood Yousaf, Dong Shik Kim, Taek Kwan Kwon, Jung Hee Park, Yong Il Kim, Jae-Hyun Park, Sung Giu Jin, Kyung Soo Kim, Kwan Hyung Cho, Dong Xun Li, Jong Oh Kim, Chul Soon Yong, Jong Soo Woo, Han-Gon Choi. Novel montelukast sodium-loaded stable oral suspension bioequivalent to the commercial granules in rats. Archives of pharmacal research. 2016 Apr; 39(4):539-546. doi: 10.1007/s12272-015-0664-x. [PMID: 26983932]
  • Vanessa Vieira, Lillian Barros, Anabela Martins, Isabel C F R Ferreira. Nutritional and Biochemical Profiling of Leucopaxillus candidus (Bres.) Singer Wild Mushroom. Molecules (Basel, Switzerland). 2016 Jan; 21(1):99. doi: 10.3390/molecules21010099. [PMID: 26784162]
  • Alan W Bowsher, Rifhat Ali, Scott A Harding, Chung-Jui Tsai, Lisa A Donovan. Evolutionary Divergences in Root Exudate Composition among Ecologically-Contrasting Helianthus Species. PloS one. 2016; 11(1):e0148280. doi: 10.1371/journal.pone.0148280. [PMID: 26824236]
  • Liangsheng Xu, Meichun Xiang, David White, Weidong Chen. pH dependency of sclerotial development and pathogenicity revealed by using genetically defined oxalate-minus mutants of Sclerotinia sclerotiorum. Environmental microbiology. 2015 Aug; 17(8):2896-909. doi: 10.1111/1462-2920.12818. [PMID: 25720941]
  • Nan-Sun Kim, Hwa-Young Yu, Nguyen-Duc Chung, Tae-Ho Kwon, Moon-Sik Yang. High-level production of recombinant trypsin in transgenic rice cell culture through utilization of an alternative carbon source and recycling system. Enzyme and microbial technology. 2014 Sep; 63(?):21-7. doi: 10.1016/j.enzmictec.2014.04.010. [PMID: 25039055]
  • Shuai Gu, Qing Xu, He Huang, Shuang Li. Alternative respiration and fumaric acid production of Rhizopus oryzae. Applied microbiology and biotechnology. 2014 Jun; 98(11):5145-52. doi: 10.1007/s00253-014-5615-9. [PMID: 24643733]
  • Agnieszka Nawirska-Olszańska, Anita Biesiada, Anna Sokół-Łętowska, Alicja Z Kucharska. Characteristics of organic acids in the fruit of different pumpkin species. Food chemistry. 2014 Apr; 148(?):415-9. doi: 10.1016/j.foodchem.2013.10.080. [PMID: 24262577]
  • Dong Tian, Zhen-Yu Li, Sheng-Ci Fan, Jin-Ping Jia, Xue-Mei Qin. [NMR-based analysis of water soluble extracts of different Astragali Radix]. Yao xue xue bao = Acta pharmaceutica Sinica. 2014 Jan; 49(1):89-94. doi: ". [PMID: 24783512]
  • Yingjiao Wang, Tyler Robison, Heather Wiatrowski. The impact of ionic mercury on antioxidant defenses in two mercury-sensitive anaerobic bacteria. Biometals : an international journal on the role of metal ions in biology, biochemistry, and medicine. 2013 Dec; 26(6):1023-31. doi: 10.1007/s10534-013-9679-2. [PMID: 24150569]
  • Neusa Martins, Sandra Gonçalves, Paula B Andrade, Patrícia Valentão, Anabela Romano. Changes on organic acid secretion and accumulation in Plantago almogravensis Franco and Plantago algarbiensis Samp. under aluminum stress. Plant science : an international journal of experimental plant biology. 2013 Jan; 198(?):1-6. doi: 10.1016/j.plantsci.2012.09.001. [PMID: 23199681]
  • Tahar Ghnaya, Hanen Zaier, Raoudha Baioui, Souhir Sghaier, Giorgio Lucchini, Gian Attilio Sacchi, Stanley Lutts, Chedly Abdelly. Implication of organic acids in the long-distance transport and the accumulation of lead in Sesuvium portulacastrum and Brassica juncea. Chemosphere. 2013 Jan; 90(4):1449-54. doi: 10.1016/j.chemosphere.2012.08.061. [PMID: 23026160]
  • Barbara Dolińska, Aneta Ostróżka-Cieślik, Artur Caban, Klimas Rimantas, Lucyna Leszczyńska, Florian Ryszka. Influence of trace elements on stabilization of aqueous solutions of ascorbic acid. Biological trace element research. 2012 Dec; 150(1-3):509-12. doi: 10.1007/s12011-012-9524-4. [PMID: 23099563]
  • T P Pirog, T A Shevchuk, A D Konon, E Iu Dolotenko. [Production of surfactants by Acinetobacter calcoaceticus K-4 grown on ethanol with organic acids]. Prikladnaia biokhimiia i mikrobiologiia. 2012 Nov; 48(6):631-9. doi: . [PMID: 23330390]
  • Huifeng Wu, Xiaoli Liu, Jianmin Zhao, Junbao Yu. Toxicological responses in halophyte Suaeda salsa to mercury under environmentally relevant salinity. Ecotoxicology and environmental safety. 2012 Nov; 85(?):64-71. doi: 10.1016/j.ecoenv.2012.03.016. [PMID: 22947507]
  • Maja Mikulic-Petkovsek, Valentina Schmitzer, Ana Slatnar, Franci Stampar, Robert Veberic. Composition of sugars, organic acids, and total phenolics in 25 wild or cultivated berry species. Journal of food science. 2012 Oct; 77(10):C1064-70. doi: 10.1111/j.1750-3841.2012.02896.x. [PMID: 22924969]
  • Michael T Rose, Terry J Rose, Juan Pariasca-Tanaka, Tadashi Yoshihashi, Heiko Neuweger, Alexander Goesmann, Michael Frei, Matthias Wissuwa. Root metabolic response of rice (Oryza sativa L.) genotypes with contrasting tolerance to zinc deficiency and bicarbonate excess. Planta. 2012 Oct; 236(4):959-73. doi: 10.1007/s00425-012-1648-4. [PMID: 22526504]
  • Sonia Dorion, Audrey Clendenning, Julie Jeukens, Joaquín J Salas, Nanhi Parveen, Andrea A Haner, R David Law, Enrique Martínez Force, Jean Rivoal. A large decrease of cytosolic triosephosphate isomerase in transgenic potato roots affects the distribution of carbon in primary metabolism. Planta. 2012 Oct; 236(4):1177-90. doi: 10.1007/s00425-012-1675-1. [PMID: 22678033]
  • Aikseng Ooi, Kyle A Furge. Fumarate hydratase inactivation in renal tumors: HIF1α, NRF2, and "cryptic targets" of transcription factors. Chinese journal of cancer. 2012 Sep; 31(9):413-20. doi: 10.5732/cjc.012.10102. [PMID: 22776233]
  • Tomohiro Osaki, Kazuo Azuma, Seiji Kurozumi, Yoshimori Takamori, Takeshi Tsuka, Tomohiro Imagawa, Yoshiharu Okamoto, Saburo Minami. Metabolomic analyses of blood plasma after oral administration of D-glucosamine hydrochloride to dogs. Marine drugs. 2012 Aug; 10(8):1873-82. doi: 10.3390/md10081873. [PMID: 23015778]
  • Jolanta Kwasniewska, Marta Grabowska, Miroslaw Kwasniewski, Bozena Kolano. Comet-FISH with rDNA probes for the analysis of mutagen-induced DNA damage in plant cells. Environmental and molecular mutagenesis. 2012 Jun; 53(5):369-75. doi: 10.1002/em.21699. [PMID: 22556029]
  • Marcella C Orwick, Peter J Judge, Jan Procek, Ljubica Lindholm, Andrea Graziadei, Andreas Engel, Gerhard Gröbner, Anthony Watts. Detergent-free formation and physicochemical characterization of nanosized lipid-polymer complexes: Lipodisq. Angewandte Chemie (International ed. in English). 2012 May; 51(19):4653-7. doi: 10.1002/anie.201201355. [PMID: 22473824]
  • Sazada Siddiqui, Mukesh K Meghvansi, Shoukat Saeed Khan. Glyphosate, alachor and maleic hydrazide have genotoxic effect on Trigonella foenum-graecum L. Bulletin of environmental contamination and toxicology. 2012 May; 88(5):659-65. doi: 10.1007/s00128-012-0570-6. [PMID: 22392005]
  • Sandesh C S Nagamani, Ayelet Erez, Brendan Lee. Argininosuccinate lyase deficiency. Genetics in medicine : official journal of the American College of Medical Genetics. 2012 May; 14(5):501-7. doi: 10.1038/gim.2011.1. [PMID: 22241104]
  • Duncan G G McMillan, Sophie J Marritt, Julea N Butt, Lars J C Jeuken. Menaquinone-7 is specific cofactor in tetraheme quinol dehydrogenase CymA. The Journal of biological chemistry. 2012 Apr; 287(17):14215-25. doi: 10.1074/jbc.m112.348813. [PMID: 22393052]
  • Dimas M Ribeiro, Wagner L Araújo, Alisdair R Fernie, Jos H M Schippers, Bernd Mueller-Roeber. Translatome and metabolome effects triggered by gibberellins during rosette growth in Arabidopsis. Journal of experimental botany. 2012 Apr; 63(7):2769-86. doi: 10.1093/jxb/err463. [PMID: 22291129]
  • Jia-Kun Wang, Jun-An Ye, Jian-Xin Liu. Effects of tea saponins on rumen microbiota, rumen fermentation, methane production and growth performance--a review. Tropical animal health and production. 2012 Apr; 44(4):697-706. doi: 10.1007/s11250-011-9960-8. [PMID: 21870063]
  • Olivier Levillain. Expression and function of arginine-producing and consuming-enzymes in the kidney. Amino acids. 2012 Apr; 42(4):1237-52. doi: 10.1007/s00726-011-0897-z. [PMID: 21567240]
  • Ruud A Timmers, Michael Rothballer, David P B T B Strik, Marion Engel, Stephan Schulz, Michael Schloter, Anton Hartmann, Bert Hamelers, Cees Buisman. Microbial community structure elucidates performance of Glyceria maxima plant microbial fuel cell. Applied microbiology and biotechnology. 2012 Apr; 94(2):537-48. doi: 10.1007/s00253-012-3894-6. [PMID: 22361855]
  • Kinga A Sędzielewska, Katja Vetter, Rüdiger Bode, Keith Baronian, Roland Watzke, Gotthard Kunze. GiFRD encodes a protein involved in anaerobic growth in the arbuscular mycorrhizal fungus Glomus intraradices. Fungal genetics and biology : FG & B. 2012 Apr; 49(4):313-21. doi: 10.1016/j.fgb.2012.02.002. [PMID: 22343635]
  • Lavanya Babujee, Jennifer Apodaca, Venkatesh Balakrishnan, Paul Liss, Patricia J Kiley, Amy O Charkowski, Jeremy D Glasner, Nicole T Perna. Evolution of the metabolic and regulatory networks associated with oxygen availability in two phytopathogenic enterobacteria. BMC genomics. 2012 Mar; 13(?):110. doi: 10.1186/1471-2164-13-110. [PMID: 22439737]
  • Richard C Sicher, Jinyoung Y Barnaby. Impact of carbon dioxide enrichment on the responses of maize leaf transcripts and metabolites to water stress. Physiologia plantarum. 2012 Mar; 144(3):238-53. doi: 10.1111/j.1399-3054.2011.01555.x. [PMID: 22150442]
  • Hank Greenway, Konstantin Y Kulichikhin, Gregory R Cawthray, Timothy D Colmer. pH regulation in anoxic rice coleoptiles at pH 3.5: biochemical pHstats and net H+ influx in the absence and presence of NOFormula. Journal of experimental botany. 2012 Mar; 63(5):1969-83. doi: 10.1093/jxb/err395. [PMID: 22174442]
  • Karin Y van Spaendonck-Zwarts, Sadhanna Badeloe, Sjoukje F Oosting, Sjoerd Hovenga, Harry J F Semmelink, R Jeroen A van Moorselaar, Jan Hein van Waesberghe, Arjen R Mensenkamp, Fred H Menko. Hereditary leiomyomatosis and renal cell cancer presenting as metastatic kidney cancer at 18 years of age: implications for surveillance. Familial cancer. 2012 Mar; 11(1):123-9. doi: 10.1007/s10689-011-9491-5. [PMID: 22086304]
  • Abhimanyu Paraskar, Shivani Soni, Bhaskar Roy, Anne-Laure Papa, Shiladitya Sengupta. Rationally designed oxaliplatin-nanoparticle for enhanced antitumor efficacy. Nanotechnology. 2012 Feb; 23(7):075103. doi: 10.1088/0957-4484/23/7/075103. [PMID: 22275055]
  • Sonia A Thomas, Kenneth B Storey, John W Baynes, Norma Frizzell. Tissue distribution of S-(2-succino)cysteine (2SC), a biomarker of mitochondrial stress in obesity and diabetes. Obesity (Silver Spring, Md.). 2012 Feb; 20(2):263-9. doi: 10.1038/oby.2011.340. [PMID: 22134201]
  • Marie-Françoise Ritz, Caspar Grond-Ginsbach, Stefan Engelter, Philippe Lyrer. Gene expression suggests spontaneously hypertensive rats may have altered metabolism and reduced hypoxic tolerance. Current neurovascular research. 2012 Feb; 9(1):10-9. doi: 10.2174/156720212799297074. [PMID: 22272763]
  • Yi-Yu Wei, Chih-Wei Huang, Wei-Yuan Chou, Hwei-Jen Lee. α-Crystallin protects human arginosuccinate lyase activity under freeze-thaw conditions. Biochimie. 2012 Feb; 94(2):566-73. doi: 10.1016/j.biochi.2011.09.006. [PMID: 21963434]
  • Claudia Catalanotti, Alexandra Dubini, Venkataramanan Subramanian, Wenqiang Yang, Leonardo Magneschi, Florence Mus, Michael Seibert, Matthew C Posewitz, Arthur R Grossman. Altered fermentative metabolism in Chlamydomonas reinhardtii mutants lacking pyruvate formate lyase and both pyruvate formate lyase and alcohol dehydrogenase. The Plant cell. 2012 Feb; 24(2):692-707. doi: 10.1105/tpc.111.093146. [PMID: 22353371]
  • Anne-Marie Boisson, Elisabeth Gout, Richard Bligny, Corinne Rivasseau. A simple and efficient method for the long-term preservation of plant cell suspension cultures. Plant methods. 2012 Jan; 8(?):4. doi: 10.1186/1746-4811-8-4. [PMID: 22289515]
  • Claudia Mamani Moreno, Teodoro Stadler, Antônio Alberto da Silva, Luiz C A Barbosa, Maria Eliana L R de Queiroz. Determination of maleic hydrazide residues in garlic bulbs by HPLC. Talanta. 2012 Jan; 89(?):369-76. doi: 10.1016/j.talanta.2011.12.045. [PMID: 22284504]
  • Ruth C Martin, Kira Glover-Cutter, James C Baldwin, James E Dombrowski. Identification and characterization of a salt stress-inducible zinc finger protein from Festuca arundinacea. BMC research notes. 2012 Jan; 5(?):66. doi: 10.1186/1756-0500-5-66. [PMID: 22272737]
  • Giancarlo la Marca, Sabrina Malvagia, Serena Materazzi, Maria Luisa Della Bona, Sara Boenzi, Diego Martinelli, Carlo Dionisi-Vici. LC-MS/MS method for simultaneous determination on a dried blood spot of multiple analytes relevant for treatment monitoring in patients with tyrosinemia type I. Analytical chemistry. 2012 Jan; 84(2):1184-8. doi: 10.1021/ac202695h. [PMID: 22148291]
  • Mingxing Yang, Shu Wang, Fuhua Hao, Yajie Li, Huiru Tang, Xuemin Shi. NMR analysis of the rat neurochemical changes induced by middle cerebral artery occlusion. Talanta. 2012 Jan; 88(?):136-44. doi: 10.1016/j.talanta.2011.10.022. [PMID: 22265479]
  • Alaa A Salem, Hussein A Mossa. Method validation and determinations of levofloxacin, metronidazole and sulfamethoxazole in an aqueous pharmaceutical, urine and blood plasma samples using quantitative nuclear magnetic resonance spectrometry. Talanta. 2012 Jan; 88(?):104-14. doi: 10.1016/j.talanta.2011.10.016. [PMID: 22265475]
  • Semih Otles, Buket Yalcin. Phenolic compounds analysis of root, stalk, and leaves of nettle. TheScientificWorldJournal. 2012; 2012(?):564367. doi: 10.1100/2012/564367. [PMID: 22593694]
  • Bing Bai, Noga Sikron, Tanya Gendler, Yana Kazachkova, Simon Barak, Gideon Grafi, Inna Khozin-Goldberg, Aaron Fait. Ecotypic variability in the metabolic response of seeds to diurnal hydration-dehydration cycles and its relationship to seed vigor. Plant & cell physiology. 2012 Jan; 53(1):38-52. doi: 10.1093/pcp/pcr169. [PMID: 22156384]
  • Mylène Pouliot, Sébastien Talbot, Jacques Sénécal, Florence Dotigny, Elvire Vaucher, Réjean Couture. Ocular application of the kinin B1 receptor antagonist LF22-0542 inhibits retinal inflammation and oxidative stress in streptozotocin-diabetic rats. PloS one. 2012; 7(3):e33864. doi: 10.1371/journal.pone.0033864. [PMID: 22470485]
  • Christopher A Lopez, Sebastian E Winter, Fabian Rivera-Chávez, Mariana N Xavier, Victor Poon, Sean-Paul Nuccio, Renée M Tsolis, Andreas J Bäumler. Phage-mediated acquisition of a type III secreted effector protein boosts growth of salmonella by nitrate respiration. mBio. 2012; 3(3):. doi: 10.1128/mbio.00143-12. [PMID: 22691391]
  • Bhavapriya Vaitheesvaran, Li Yang, Kirsten Hartil, Sherrye Glaser, Stephen Yazulla, James E Bruce, Irwin J Kurland. Peripheral effects of FAAH deficiency on fuel and energy homeostasis: role of dysregulated lysine acetylation. PloS one. 2012; 7(3):e33717. doi: 10.1371/journal.pone.0033717. [PMID: 22442717]
  • Patrick Ying-Kit Yue, Yi-Yi Wong, Tony Yuk-Kit Chan, Carman Ka-Man Law, Yeuk-Ki Tsoi, Kelvin Sze-Yin Leung. Review of biological and pharmacological activities of the endemic Taiwanese bitter medicinal mushroom, Antrodia camphorata (M. Zang et C. H. Su) Sh. H. Wu et al. (higher Basidiomycetes). International journal of medicinal mushrooms. 2012; 14(3):241-56. doi: 10.1615/intjmedmushr.v14.i3.20. [PMID: 22577975]
  • Yang Sun, Zeqin Lian, Chunying Jiang, Yinghong Wang, Haibo Zhu. Beneficial metabolic effects of 2',3',5'-tri-acetyl-N6- (3-hydroxylaniline) adenosine in the liver and plasma of hyperlipidemic hamsters. PloS one. 2012; 7(3):e32115. doi: 10.1371/journal.pone.0032115. [PMID: 22470419]
  • Liezel M Gouws, Eileen Botes, Anna J Wiese, Sandra Trenkamp, Ivone Torres-Jerez, Yuhong Tang, Paul N Hills, Björn Usadel, James R Lloyd, Alisdair R Fernie, Jens Kossmann, Margaretha J van der Merwe. The plant growth promoting substance, lumichrome, mimics starch, and ethylene-associated symbiotic responses in lotus and tomato roots. Frontiers in plant science. 2012; 3(?):120. doi: 10.3389/fpls.2012.00120. [PMID: 22701462]
  • Jun Tian, Xiaoquan Ban, Hong Zeng, Jingsheng He, Yuxin Chen, Youwei Wang. The mechanism of antifungal action of essential oil from dill (Anethum graveolens L.) on Aspergillus flavus. PloS one. 2012; 7(1):e30147. doi: 10.1371/journal.pone.0030147. [PMID: 22272289]
  • Ana Carolina Ariza, Peter Meinardus T Deen, Joris Hubertus Robben. The succinate receptor as a novel therapeutic target for oxidative and metabolic stress-related conditions. Frontiers in endocrinology. 2012; 3(?):22. doi: 10.3389/fendo.2012.00022. [PMID: 22649411]
  • Guangguo Tan, Wenting Liao, Xin Dong, Genjing Yang, Zhenyu Zhu, Wuhong Li, Yifeng Chai, Ziyang Lou. Metabonomic profiles delineate the effect of traditional Chinese medicine sini decoction on myocardial infarction in rats. PloS one. 2012; 7(4):e34157. doi: 10.1371/journal.pone.0034157. [PMID: 22493681]
  • Alexandra Maier, Holger Fahnenstich, Susanne von Caemmerer, Martin K M Engqvist, Andreas P M Weber, Ulf-Ingo Flügge, Veronica G Maurino. Transgenic Introduction of a Glycolate Oxidative Cycle into A. thaliana Chloroplasts Leads to Growth Improvement. Frontiers in plant science. 2012; 3(?):38. doi: 10.3389/fpls.2012.00038. [PMID: 22639647]
  • David Toubiana, Yaniv Semel, Takayuki Tohge, Romina Beleggia, Luigi Cattivelli, Leah Rosental, Zoran Nikoloski, Dani Zamir, Alisdair R Fernie, Aaron Fait. Metabolic profiling of a mapping population exposes new insights in the regulation of seed metabolism and seed, fruit, and plant relations. PLoS genetics. 2012; 8(3):e1002612. doi: 10.1371/journal.pgen.1002612. [PMID: 22479206]
  • Stewart Frankel, Blanka Rogina. Indy mutants: live long and prosper. Frontiers in genetics. 2012; 3(?):13. doi: 10.3389/fgene.2012.00013. [PMID: 22363340]
  • Stephanus J Ferreira, Uwe Sonnewald. The mode of sucrose degradation in potato tubers determines the fate of assimilate utilization. Frontiers in plant science. 2012; 3(?):23. doi: 10.3389/fpls.2012.00023. [PMID: 22639642]
  • Fabien Baldacci-Cresp, Christine Chang, Mickaël Maucourt, Catherine Deborde, Julie Hopkins, Philippe Lecomte, Stéphane Bernillon, Renaud Brouquisse, Annick Moing, Pierre Abad, Didier Hérouart, Alain Puppo, Bruno Favery, Pierre Frendo. (Homo)glutathione deficiency impairs root-knot nematode development in Medicago truncatula. PLoS pathogens. 2012 Jan; 8(1):e1002471. doi: 10.1371/journal.ppat.1002471. [PMID: 22241996]
  • Ilka Haferkamp, Stephan Schmitz-Esser. The plant mitochondrial carrier family: functional and evolutionary aspects. Frontiers in plant science. 2012; 3(?):2. doi: 10.3389/fpls.2012.00002. [PMID: 22639632]
  • Zhengyuan Wang, Jianqin Sun, Lu Wang, Min Zong, Yanqiu Chen, Yifan Lin, Danfeng Xu, Jingjing Jiang, Yiru Pan, Jianhua Piao, Zhenwu Huang, Xiaoguang Yang. [Effect of iron supplementation on iron deficiency anemia of childbearing age women in Shanghai]. Wei sheng yan jiu = Journal of hygiene research. 2012 Jan; 41(1):51-5. doi: NULL. [PMID: 22443058]
  • Tahmineh Khazaei, Alison McGuigan, Radhakrishnan Mahadevan. Ensemble modeling of cancer metabolism. Frontiers in physiology. 2012; 3(?):135. doi: 10.3389/fphys.2012.00135. [PMID: 22623918]
  • Marcus Thein, Mari Bonde, Ignas Bunikis, Katrin Denker, Albert Sickmann, Sven Bergström, Roland Benz. DipA, a pore-forming protein in the outer membrane of Lyme disease spirochetes exhibits specificity for the permeation of dicarboxylates. PloS one. 2012; 7(5):e36523. doi: 10.1371/journal.pone.0036523. [PMID: 22590556]
  • Weiguo Sui, Liping Li, Wenti Che, Zuo Guimai, Jiejing Chen, Wuxian Li, Yong Dai. A proton nuclear magnetic resonance-based metabonomics study of metabolic profiling in immunoglobulin a nephropathy. Clinics (Sao Paulo, Brazil). 2012; 67(4):363-73. doi: 10.6061/clinics/2012(04)10. [PMID: 22522762]
  • Hervé Colinet, David Renault, Blandine Charoy-Guével, Emmanuelle Com. Metabolic and proteomic profiling of diapause in the aphid parasitoid Praon volucre. PloS one. 2012; 7(2):e32606. doi: 10.1371/journal.pone.0032606. [PMID: 22389713]
  • Laura Brugnara, Maria Vinaixa, Serafín Murillo, Sara Samino, Miguel Angel Rodriguez, Antoni Beltran, Carles Lerin, Gareth Davison, Xavier Correig, Anna Novials. Metabolomics approach for analyzing the effects of exercise in subjects with type 1 diabetes mellitus. PloS one. 2012; 7(7):e40600. doi: 10.1371/journal.pone.0040600. [PMID: 22792382]
  • Zhongmin Alex Ma, Zhengshan Zhao, John Turk. Mitochondrial dysfunction and β-cell failure in type 2 diabetes mellitus. Experimental diabetes research. 2012; 2012(?):703538. doi: 10.1155/2012/703538. [PMID: 22110477]
  • Tarek Baati, Patricia Horcajada, Ruxandra Gref, Patrick Couvreur, Christian Serre. Quantification of fumaric acid in liver, spleen and urine by high-performance liquid chromatography coupled to photodiode-array detection. Journal of pharmaceutical and biomedical analysis. 2011 Dec; 56(4):758-62. doi: 10.1016/j.jpba.2011.07.011. [PMID: 21820831]
  • Yao Zhang, Bo Huang, Zhi Zhao, Ying Zhou. [Study on the chemical constituents from the ethyl acetate extracts of Cremastra appendiculata]. Zhong yao cai = Zhongyaocai = Journal of Chinese medicinal materials. 2011 Dec; 34(12):1882-3. doi: . [PMID: 22500423]
  • Jacobien Veenemans, Paul Milligan, Andrew M Prentice, Laura R A Schouten, Nienke Inja, Aafke C van der Heijden, Linsey C C de Boer, Esther J S Jansen, Anna E Koopmans, Wendy T M Enthoven, Rob J Kraaijenhagen, Ayse Y Demir, Donald R A Uges, Erasto V Mbugi, Huub F J Savelkoul, Hans Verhoef. Effect of supplementation with zinc and other micronutrients on malaria in Tanzanian children: a randomised trial. PLoS medicine. 2011 Nov; 8(11):e1001125. doi: 10.1371/journal.pmed.1001125. [PMID: 22131908]
  • Julie Adam, Peter J Ratcliffe, Patrick J Pollard. Novel insights into FH-associated disease are KEAPing the lid on oncogenic HIF signalling. Oncotarget. 2011 Nov; 2(11):820-1. doi: 10.18632/oncotarget.348. [PMID: 22064867]
  • Anne-Sophie Foltête, Adrien Dhyèvre, Jean-François Férard, Sylvie Cotelle. Improvement of Vicia-micronucleus test for assessment of soil quality: a proposal for international standardization. Chemosphere. 2011 Nov; 85(10):1624-9. doi: 10.1016/j.chemosphere.2011.08.026. [PMID: 21906776]
  • Saber Khelaifia, Marie-Laure Fardeau, Nathalie Pradel, Clément Aussignargues, Marc Garel, Christian Tamburini, Jean-Luc Cayol, Sylvie Gaudron, Françoise Gaill, Bernard Ollivier. Desulfovibrio piezophilus sp. nov., a piezophilic, sulfate-reducing bacterium isolated from wood falls in the Mediterranean Sea. International journal of systematic and evolutionary microbiology. 2011 Nov; 61(Pt 11):2706-2711. doi: 10.1099/ijs.0.028670-0. [PMID: 21169465]
  • Ehud Katz, Kyung Hwan Boo, Ho Youn Kim, Richard A Eigenheer, Brett S Phinney, Vladimir Shulaev, Florence Negre-Zakharov, Avi Sadka, Eduardo Blumwald. Label-free shotgun proteomics and metabolite analysis reveal a significant metabolic shift during citrus fruit development. Journal of experimental botany. 2011 Nov; 62(15):5367-84. doi: 10.1093/jxb/err197. [PMID: 21841177]
  • Sergi Garcia-Segura, Lucio Cesar Almeida, Nerilso Bocchi, Enric Brillas. Solar photoelectro-Fenton degradation of the herbicide 4-chloro-2-methylphenoxyacetic acid optimized by response surface methodology. Journal of hazardous materials. 2011 Oct; 194(?):109-18. doi: 10.1016/j.jhazmat.2011.07.089. [PMID: 21872394]
  • Haymo Pircher, Grit D Straganz, Daniela Ehehalt, Geneviève Morrow, Robert M Tanguay, Pidder Jansen-Dürr. Identification of human fumarylacetoacetate hydrolase domain-containing protein 1 (FAHD1) as a novel mitochondrial acylpyruvase. The Journal of biological chemistry. 2011 Oct; 286(42):36500-8. doi: 10.1074/jbc.m111.264770. [PMID: 21878618]
  • Aikseng Ooi, Jing-Chii Wong, David Petillo, Douglas Roossien, Victoria Perrier-Trudova, Douglas Whitten, Bernice Wong Hui Min, Min-Han Tan, Zhongfa Zhang, Ximing J Yang, Ming Zhou, Betty Gardie, Vincent Molinié, Stéphane Richard, Puay Hoon Tan, Bin Tean Teh, Kyle A Furge. An antioxidant response phenotype shared between hereditary and sporadic type 2 papillary renal cell carcinoma. Cancer cell. 2011 Oct; 20(4):511-23. doi: 10.1016/j.ccr.2011.08.024. [PMID: 22014576]
  • Julie Adam, Emine Hatipoglu, Linda O'Flaherty, Nicola Ternette, Natasha Sahgal, Helen Lockstone, Dilair Baban, Emma Nye, Gordon W Stamp, Kathryn Wolhuter, Marcus Stevens, Roman Fischer, Peter Carmeliet, Patrick H Maxwell, Chris W Pugh, Norma Frizzell, Tomoyoshi Soga, Benedikt M Kessler, Mona El-Bahrawy, Peter J Ratcliffe, Patrick J Pollard. Renal cyst formation in Fh1-deficient mice is independent of the Hif/Phd pathway: roles for fumarate in KEAP1 succination and Nrf2 signaling. Cancer cell. 2011 Oct; 20(4):524-37. doi: 10.1016/j.ccr.2011.09.006. [PMID: 22014577]
  • Kashif Ali, Federica Maltese, Ana Margarida Fortes, Maria Salomé Pais, Robert Verpoorte, Young Hae Choi. Pre-analytical method for NMR-based grape metabolic fingerprinting and chemometrics. Analytica chimica acta. 2011 Oct; 703(2):179-86. doi: 10.1016/j.aca.2011.07.036. [PMID: 21889632]
  • Xiaoying Zheng, Mingming Su, Lijun Pei, Ting Zhang, Xu Ma, Yunping Qiu, Hongfei Xia, Fang Wang, Xiaojiao Zheng, Xue Gu, Xinming Song, Xin Li, Xin Qi, Gong Chen, Yihua Bao, Tianlu Chen, Yi Chi, Aihua Zhao, Wei Jia. Metabolic signature of pregnant women with neural tube defects in offspring. Journal of proteome research. 2011 Oct; 10(10):4845-54. doi: 10.1021/pr200666d. [PMID: 21902205]
  • Kalie Van Ree, Bernadette Gehl, E Wassim Chehab, Yu-Chang Tsai, Janet Braam. Nitric oxide accumulation in Arabidopsis is independent of NOA1 in the presence of sucrose. The Plant journal : for cell and molecular biology. 2011 Oct; 68(2):225-33. doi: 10.1111/j.1365-313x.2011.04680.x. [PMID: 21689173]
  • Hyo Jeong Kim, Se Jin Park, Kook In Park, Jin Sung Lee, Ho Sun Eun, Ji Hong Kim, Jae Il Shin. Acute treatment of hyperammonemia by continuous renal replacement therapy in a newborn patient with ornithine transcarbamylase deficiency. Korean journal of pediatrics. 2011 Oct; 54(10):425-8. doi: 10.3345/kjp.2011.54.10.425. [PMID: 22232626]