5-Methoxycanthin-6-one (BioDeep_00000017656)

 

Secondary id: BioDeep_00000616166

human metabolite PANOMIX_OTCML-2023 Endogenous


代谢物信息卡片


3-methoxy-1,6-diazatetracyclo[7.6.1.0^{5,16}.0^{10,15}]hexadeca-3,5(16),6,8,10,12,14-heptaen-2-one

化学式: C15H10N2O2 (250.07422400000002)
中文名称:
谱图信息: 最多检出来源 Chinese Herbal Medicine(otcml) 1.63%

分子结构信息

SMILES: c1c2c3c(nc1)cc(c(=O)n3c1c2cccc1)OC
InChI: InChI=1S/C15H10N2O2/c1-19-13-8-11-14-10(6-7-16-11)9-4-2-3-5-12(9)17(14)15(13)18/h2-8H,1H3

描述信息

5-Methoxycanthin-6-one is an alkaloid and an organic heterotetracyclic compound.
5-Methoxycanthin-6-one is a natural product found in Zanthoxylum caribaeum, Fagaropsis angolensis, and other organisms with data available.
5-Methoxycanthin-6-one is an alkaloid from the wood of Picrasma excelsa (Jamaican quassiawood

同义名列表

18 个代谢物同义名

3-methoxy-1,6-diazatetracyclo[7.6.1.0^{5,16}.0^{10,15}]hexadeca-3,5(16),6,8,10,12,14-heptaen-2-one; 3-methoxy-1,6-diazatetracyclo[7.6.1.0?,??.0??,??]hexadeca-3,5,7,9(16),10(15),11,13-heptaen-2-one; 3-methoxy-1,6-diazatetracyclo[7.6.1.0⁵,¹⁶.0¹⁰,¹⁵]hexadeca-3,5,7,9(16),10,12,14-heptaen-2-one; 3-methoxy-1,6-diazatetracyclo[7.6.1.05,16.010,15]hexadeca-3,5(16),6,8,10,12,14-heptaen-2-one; 5-Methoxy-6H-indolo[3,2,1-de][1,5]naphthyridin-6-one, 9CI; 6H-Indolo[3,2,1-de][1,5]naphthyridin-6-one, 5-methoxy-; 6H-Indolo(3,2,1-de)(1,5)naphthyridin-6-one, 5-methoxy-; 5-Methoxy-6H-indolo(3,2,1-de)(1,5)naphthyridin-6-one; 5-Methoxy-6H-indolo[3,2,1-de][1,5]naphthyridin-6-one; TXEFUSAHPIYZHD-UHFFFAOYSA-N; Canthin-6-one, 5-methoxy-; 5-methoxy-canthin-6-one; METHOXYCANTHIN-6-ONE,5-; 5-Methoxycanthin-6-one; Methoxycanthinone, 5-; 5-Methoxycanthinone; UNII-VVM1A8LM35; VVM1A8LM35



数据库引用编号

12 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(0)

BioCyc(0)

PlantCyc(0)

代谢反应

0 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

11 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：

  • PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。



文献列表

  • Xiaolei Miao, Junjun Wang, Yong Chen. Pharmacokinetics and tissue distribution of 4,5-dimethoxycanthin-6-one and its major metabolites in rats. Journal of pharmaceutical and biomedical analysis. 2017 May; 139(?):22-29. doi: 10.1016/j.jpba.2017.01.015. [PMID: 28258983]
  • Gerardo Cebrián-Torrejón, Antonio Doménech-Carbó, Bruno Figadère, Erwan Poupon, Alain Fournet. Phytoelectrochemical analysis of Zanthoxylum chiloperone. Phytochemical analysis : PCA. 2017 May; 28(3):171-175. doi: 10.1002/pca.2657. [PMID: 27995663]
  • Yuanyuan Shi, Yuanyuan Xia, Jueyu Wang, Jinfeng He, Feng Feng, Wenyuan Liu. Metabolic profile of 5-hydroxy-4-methoxycanthin-6-one, a typical canthinone alkaloid, in rats determined by liquid chromatography-quadrupole time-of-flight tandem mass spectrometry together with multiple data processing techniques. Journal of pharmaceutical and biomedical analysis. 2016 Sep; 129(?):60-69. doi: 10.1016/j.jpba.2016.06.047. [PMID: 27399343]
  • Gerardo Cebrián-Torrejón, Landry Kablan, Maria Elena Ferreira, David Rodríguez de la Cruz, Antonio Doménech-Carbó, Ninfa Vera de Bilbao, Antonieta Rojas de Arias, Bruno Figadère, Erwan Poupon, Alain Fournet. Harvesting canthinones: identification of the optimal seasonal point of harvest of Zanthoxylum chiloperone leaves as a source of 5-methoxycanthin-6-one. Natural product research. 2015; 29(21):2054-8. doi: 10.1080/14786419.2015.1022774. [PMID: 25782699]
  • Jia Chen, Xiao-Hui Yan, Jia-Hong Dong, Peng Sang, Xin Fang, Ying-Tong Di, Zhong-Kai Zhang, Xiao-Jiang Hao. Tobacco mosaic virus (TMV) inhibitors from Picrasma quassioides Benn. Journal of agricultural and food chemistry. 2009 Aug; 57(15):6590-5. doi: 10.1021/jf901632j. [PMID: 19586051]
  • Céline Thouvenel, Jean-Charles Gantier, Philippe Duret, Christophe Fourneau, Reynald Hocquemiller, Maria-Elena Ferreira, Antonieta Rojas de Arias, Alain Fournet. Antifungal compounds from Zanthoxylum chiloperone var. angustifolium. Phytotherapy research : PTR. 2003 Jun; 17(6):678-80. doi: 10.1002/ptr.1137. [PMID: 12820240]
  • M E Ferreira, A Rojas de Arias, S Torres de Ortiz, A Inchausti, H Nakayama, C Thouvenel, R Hocquemiller, A Fournet. Leishmanicidal activity of two canthin-6-one alkaloids, two major constituents of Zanthoxylum chiloperone var. angustifolium. Journal of ethnopharmacology. 2002 May; 80(2-3):199-202. doi: 10.1016/s0378-8741(02)00025-9. [PMID: 12007711]
  • L A Anderson, A Harris, J D Phillipson. Production of cytotoxic canthin-6-one alkaloids by Ailanthus altissima plant cell cultures. Journal of natural products. 1983 May; 46(3):374-8. doi: 10.1021/np50027a014. [PMID: 6619885]