(4-Hydroxy-3-methoxyphenyl)ethanol (BioDeep_00000017620)

 

Secondary id: BioDeep_00000591747, BioDeep_00000865638

human metabolite PANOMIX_OTCML-2023 blood metabolite


代谢物信息卡片


4-Hydroxy-3-methoxyphenethanol pound>>4-(2-Hydroxyethyl)-2-methoxyphenol

化学式: C9H12O3 (168.0786402)
中文名称: 高香草醇, 4-羟基-3-甲氧基苯乙醇
谱图信息: 最多检出来源 Viridiplantae(plant) 0.88%

分子结构信息

SMILES: COC1=C(C=CC(=C1)CCO)O
InChI: InChI=1S/C9H12O3/c1-12-9-6-7(4-5-10)2-3-8(9)11/h2-3,6,10-11H,4-5H2,1H3

描述信息

(4-Hydroxy-3-methoxyphenyl)ethanol is a member of methoxybenzenes and a member of phenols.
Homovanillyl alcohol is a natural product found in Saussurea medusa, Urtica dioica, and other organisms with data available.
Homovanillyl alcohol is a metabolite found in or produced by Saccharomyces cerevisiae.
Metabolite of serotonin and norepinephrine.
(4-Hydroxy-3-methoxyphenyl)ethanol is isolated from various plant species (4-Hydroxy-3-methoxyphenyl)ethanol is a constituent of mandibular secretion of honeybees [CCD].
Isolated from various plant subspecies Constituent of mandibular secretion of honeybees [CCD]
Homovanillyl alcohol is a biological metabolite of Hydroxytyrosol. Hydroxytyrosol is a phenolic compound that is present in virgin olive oil (VOO) and wine. Homovanillyl alcohol protects red blood cells (RBCs) from oxidative injury and has protective effect on cardiovascular disease[1][2].
Homovanillyl alcohol is a biological metabolite of Hydroxytyrosol. Hydroxytyrosol is a phenolic compound that is present in virgin olive oil (VOO) and wine. Homovanillyl alcohol protects red blood cells (RBCs) from oxidative injury and has protective effect on cardiovascular disease[1][2].

同义名列表

32 个代谢物同义名

4-Hydroxy-3-methoxyphenethanol pound>>4-(2-Hydroxyethyl)-2-methoxyphenol; InChI=1/C9H12O3/c1-12-9-6-7(4-5-10)2-3-8(9)11/h2-3,6,10-11H,4-5H2,1H3; 4-Hydroxy-3-methoxyphenylethyl alcohol; 2-(4-Hydroxy-3-methoxyphenyl)-ethanol; 4-(2-Hydroxyethyl)-2-methoxyphenol #; Benzeneethanol, 4-hydroxy-3-methoxy-; 4-Hydroxy-3-methoxyphenethyl alcohol; 4-(2-hydroxyethyl)-2-methoxy-phenol; 4-Hydroxy-3-methoxy-Benzeneethanol; (4-Hydroxy-3-methoxyphenyl)ethanol; 4-(2-Hydroxyethyl)-2-methoxyphenol; 4-Hydroxy-3-methoxybenzeneethanol; 3-Methoxy-4-hydroxyphenylethanol; 3 Methoxy 4 hydroxyphenylethanol; Alcohol, Hydroxymethoxyphenethyl; Hydroxymethoxyphenethyl Alcohol; 4-Hydroxy-3-methoxyphenethanol; Methoxyhydroxyphenylethanol; Homovanillyl alcohol, 99\\%; 4-(2-Hydroxyethyl)guaiacol; XHUBSJRBOQIZNI-UHFFFAOYSA-; 2-(4-Guaiacyl)-ethanol; Homovanilline alcohol; Homovanillyl alcohol; Homovanillin alcohol; Vanillylmethanol; Guaiacyl ethanol; UNII-9A7EE8MS6A; 9A7EE8MS6A; MOPET; MHPE; VTL



数据库引用编号

12 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(0)

BioCyc(0)

PlantCyc(0)

代谢反应

0 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

11 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：

  • PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。



文献列表

  • Martha-Estrella García-Pérez, Mariana Royer, Gaëtan Herbette, Yves Desjardins, Roxane Pouliot, Tatjana Stevanovic. Picea mariana bark: a new source of trans-resveratrol and other bioactive polyphenols. Food chemistry. 2012 Dec; 135(3):1173-82. doi: 10.1016/j.foodchem.2012.05.050. [PMID: 22953840]
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  • Monica Deiana, Giulia Corona, Alessandra Incani, Debora Loru, Antonella Rosa, Angela Atzeri, M Paola Melis, M Assunta Dessì. Protective effect of simple phenols from extravirgin olive oil against lipid peroxidation in intestinal Caco-2 cells. Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association. 2010 Oct; 48(10):3008-16. doi: 10.1016/j.fct.2010.07.041. [PMID: 20691238]
  • Olha Khymenets, Montserat Fitó, Sonia Touriño, Daniel Muñoz-Aguayo, Mitona Pujadas, Josep Lluis Torres, Jesús Joglar, Magí Farré, Maria-Isabel Covas, Rafael de la Torre. Antioxidant activities of hydroxytyrosol main metabolites do not contribute to beneficial health effects after olive oil ingestion. Drug metabolism and disposition: the biological fate of chemicals. 2010 Sep; 38(9):1417-21. doi: 10.1124/dmd.110.032821. [PMID: 20516254]
  • Alessandra Incani, Monica Deiana, Giulia Corona, Katerina Vafeiadou, David Vauzour, M Assunta Dessì, Jeremy P E Spencer. Involvement of ERK, Akt and JNK signalling in H2O2-induced cell injury and protection by hydroxytyrosol and its metabolite homovanillic alcohol. Molecular nutrition & food research. 2010 Jun; 54(6):788-96. doi: 10.1002/mnfr.200900098. [PMID: 20024934]
  • Fotini N Bazoti, Evangelos Gikas, Anthony Tsarbopoulos. Simultaneous quantification of oleuropein and its metabolites in rat plasma by liquid chromatography electrospray ionization tandem mass spectrometry. Biomedical chromatography : BMC. 2010 May; 24(5):506-15. doi: 10.1002/bmc.1319. [PMID: 19795379]
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  • Su-Mei Li, Xian-Wen Yang, Yong-Li Li, Yun-Heng Shen, Lin Feng, Yue-Hu Wang, Hua-Wu Zeng, Xiao-Hua Liu, Chang-Sheng Zhang, Chun-Lin Long, Wei-Dong Zhang. Chemical constituents of Dracocephalum forrestii. Planta medica. 2009 Dec; 75(15):1591-6. doi: 10.1055/s-0029-1185868. [PMID: 19579184]
  • Caterina Manna, Daniela Napoli, Giovanna Cacciapuoti, Marina Porcelli, Vincenzo Zappia. Olive oil phenolic compounds inhibit homocysteine-induced endothelial cell adhesion regardless of their different antioxidant activity. Journal of agricultural and food chemistry. 2009 May; 57(9):3478-82. doi: 10.1021/jf8037659. [PMID: 19358606]
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  • Monica Deiana, Alessandra Incani, Antonella Rosa, Giulia Corona, Angela Atzeri, Debora Loru, M Paola Melis, M Assunta Dessì. Protective effect of hydroxytyrosol and its metabolite homovanillic alcohol on H(2)O(2) induced lipid peroxidation in renal tubular epithelial cells. Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association. 2008 Sep; 46(9):2984-90. doi: 10.1016/j.fct.2008.05.037. [PMID: 18588937]
  • Mario Dell'Agli, Omar Maschi, Germana V Galli, Rossana Fagnani, Esther Dal Cero, Donatella Caruso, Enrica Bosisio. Inhibition of platelet aggregation by olive oil phenols via cAMP-phosphodiesterase. The British journal of nutrition. 2008 May; 99(5):945-51. doi: 10.1017/s0007114507837470. [PMID: 17927845]
  • Guangmiao Fu, Haihong Pang, Yung H Wong. Naturally occurring phenylethanoid glycosides: potential leads for new therapeutics. Current medicinal chemistry. 2008; 15(25):2592-613. doi: 10.2174/092986708785908996. [PMID: 18855681]
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