Docosanol (BioDeep_00000017472)

Main id: BioDeep_00000406887

Secondary id: BioDeep_00000594470, BioDeep_00000860021

human metabolite PANOMIX_OTCML-2023 blood metabolite Chemicals and Drugs Antibiotics


代谢物信息卡片


InChI=1/C22H46O/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-18-19-20-21-22-23/h23H,2-22H2,1H

化学式: C22H46O (326.3548466)
中文名称: 1-二十二醇, 正二十二醇
谱图信息: 最多检出来源 () 0%

分子结构信息

SMILES: C(CCCCCCCCCCCCCO)CCCCCCCC
InChI: InChI=1S/C22H46O/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-18-19-20-21-22-23/h23H,2-22H2,1H3

描述信息

Docosan-1-ol is a long-chain primary fatty alcohol that is docosane substituted by a hydroxy group at position 1. It has a role as an antiviral agent. It is a long-chain primary fatty alcohol and a fatty alcohol 22:0. It derives from a hydride of a docosane.
Docosanol is a drug used for topical treatment for recurrent herpes simplex labialis episodes (episodes of cold sores or fever blisters). A saturated 22-carbon aliphatic alcohol, docosanol exhibits antiviral activity against many lipid enveloped viruses including herpes simplex virus (HSV). Docosanol inhibits fusion between the plasma membrane and the herpes simplex virus (HSV) envelope, thereby preventing viral entry into cells and subsequent viral replication.
Docosanol is a natural product found in Populus tremula, Hypericum laricifolium, and other organisms with data available.
Docosanol is a saturated 22-carbon aliphatic alcohol with antiviral activity. Docosanol has a distinct mechanism of action and inhibits fusion between the plasma membrane and the herpes simplex virus envelope, thereby preventing viral entry into cells and subsequent viral activity and replication. Docosanol is used topically in the treatment of recurrent herpes simplex labialis episodes and relieves associated pain and may help heal sores faster.
Docosanol is a drug used for topical treatment for recurrent herpes simplex labialis episodes (episodes of cold sores or fever blisters). A saturated 22-carbon aliphatic alcohol, docosanol exhibits antiviral activity against many lipid enveloped viruses including herpes simplex virus (HSV). Docosanol inhibits fusion between the plasma membrane and the herpes simplex virus (HSV) envelope, thereby preventing viral entry into cells and subsequent viral replication.
Docosanol is a saturated 22-carbon aliphatic alcohol which exhibits antiviral activity against many lipid enveloped viruses including herpes simplex virus (HSV). Docosanol speeds the healing of cold sores and fever blisters on the face or lips. It also relieves the accompanying symptoms, including tingling, pain, burning, and itching. Docosanol cannot, however, prevent cold sores or fever blisters from appearing. Docosan-1-ol is found in ginkgo nuts and potato.
A long-chain primary fatty alcohol that is docosane substituted by a hydroxy group at position 1. It is a non-prescription medicine approved by the FDA to shorten healing time of cold sores.
D - Dermatologicals > D06 - Antibiotics and chemotherapeutics for dermatological use > D06B - Chemotherapeutics for topical use > D06BB - Antivirals
D000890 - Anti-Infective Agents > D000998 - Antiviral Agents
C254 - Anti-Infective Agent > C281 - Antiviral Agent
1-Docosanol is a saturated fatty alcohol with reported inhibitory activity against lipid-enveloped viruses, including herpes simplex virus.
1-Docosanol is a saturated fatty alcohol with reported inhibitory activity against lipid-enveloped viruses, including herpes simplex virus.

同义名列表

51 个代谢物同义名

InChI=1/C22H46O/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-18-19-20-21-22-23/h23H,2-22H2,1H; Behenyl alcohol, AI3-36489, Behenic alcohol, 1-Docosanol, Docosyl alcohol, IK-2, Tadenan; 4-01-00-01906 (Beilstein Handbook Reference); A3D72D45-625E-49B5-B0FC-394010B3485D; 1-Docosanol, purum, >=97.0\\% (GC); Cold Sore Fever Blister Treatment; Cold Sore Fever Blister; DOCOSANOL [ORANGE BOOK]; BEHENYL ALCOHOL [INCI]; Docosanol (Abreva); DOCOSANOL [WHO-DD]; DOCOSANOL (MART.); DOCOSANOL [VANDF]; 1-Docosanol, 98\\%; DOCOSANOL [MART.]; DOCOSANOL [HSDB]; Docosanol (USAN); N-DOCOSANOL [MI]; Docosanol [USAN]; Docosanol (VAN); behenyl alcohol; Docosyl alcohol; UNII-9G1OE216XY; Behenic alcohol; DOCOSANOL [II]; Cachalot BE-22; DOCOSANOL (II); n-Docosan-1-ol; Docosanol-(1); docosan-1-ol; Tox21_111611; Nacol 22-97; 1-Docosonol; Abreva (TN); n-Docosanol; 1-Docosanol; 9G1OE216XY; Lanette 22; AI3-36489; Docosanol; Erazaban; FOH 22:0; Herepair; C22H46O; Lidavol; Tadenan; Lidakol; Healip; Abreva; IK 2; IK.2



数据库引用编号

21 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(0)

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PlantCyc(0)

代谢反应

0 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

27 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：

  • PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。



文献列表

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  • Wei Shao, Arghya Paul, Bin Zhao, Crystal Lee, Laetitia Rodes, Satya Prakash. Carbon nanotube lipid drug approach for targeted delivery of a chemotherapy drug in a human breast cancer xenograft animal model. Biomaterials. 2013 Dec; 34(38):10109-19. doi: 10.1016/j.biomaterials.2013.09.007. [PMID: 24060420]
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