Norsanguinarine (BioDeep_00000017434)

   

human metabolite PANOMIX_OTCML-2023 Endogenous


代谢物信息卡片


5,7,18,20-tetraoxa-24-azahexacyclo[11.11.0.0^{2,10}.0^{4,8}.0^{14,22}.0^{17,21}]tetracosa-1(24),2,4(8),9,11,13,15,17(21),22-nonaene

化学式: C19H11NO4 (317.0688)
中文名称: 去甲血根碱
谱图信息: 最多检出来源 Chinese Herbal Medicine(otcml) 25.92%

分子结构信息

SMILES: c12c(cc3c(c1)ccc1c3ncc3c1ccc1c3OCO1)OCO2
InChI: InChI=1S/C19H11NO4/c1-2-12-11-3-4-15-19(24-9-21-15)14(11)7-20-18(12)13-6-17-16(5-10(1)13)22-8-23-17/h1-7H,8-9H2

描述信息

Norsanguinarine is a member of phenanthridines.
Norsanguinarine is a natural product found in Fumaria indica, Corydalis balansae, and other organisms with data available.
Norsanguinarine is found in opium poppy. Norsanguinarine is an alkaloid from Papaver rhoeas (corn poppy
D002492 - Central Nervous System Depressants > D009294 - Narcotics > D053610 - Opiate Alkaloids

同义名列表

21 个代谢物同义名

5,7,18,20-tetraoxa-24-azahexacyclo[11.11.0.0^{2,10}.0^{4,8}.0^{14,22}.0^{17,21}]tetracosa-1(24),2,4(8),9,11,13,15,17(21),22-nonaene; 5,7,18,20-tetraoxa-24-azahexacyclo[11.11.0.0^{2,10}.0^{4,8}.0^{14,22}.0^{17,21}]tetracosa-1(13),2,4(8),9,11,14,16,21,23-nonaene; 5,7,18,20-tetraoxa-24-azahexacyclo[11.11.0.02,10.04,8.014,22.017,21]tetracosa-1(24),2,4(8),9,11,13,15,17(21),22-nonaene; [1,3]Dioxolo[4,5:4,5]benzo[1,2-c][1,3]dioxolo[4,5-i]phenanthridine; 2H,10H-[1,3]Benzodioxolo[5,6-c][1,3]dioxolo[4,5-i]phenanthridine; 1,3-Dioxolo[i][1,3]dioxolo[4,5]benzo[1,2-c]phenanthridine; [1,3]Benzodioxolo[5,6-c]-1,3-dioxolo[4,5-i]phenanthridine; 1,3-Dioxolo(i)(1,3)dioxolo(4,5)benzo(1,2-c)phenanthridine; (1,3)Benzodioxolo(5,6-c)-1,3-dioxolo(4,5-i)phenanthridine; 7,8-Bis(methylenedioxy)benzo[c]phenanthridine; 1,3]dioxolo[4,5]benzo[1,2-c]phenanthridine; [1,6-c]-1,3-dioxolo[4,5-i]phenanthridine; CNXVDVMAYXLWPD-UHFFFAOYSA-N; Sanguinarine, 13-demethyl-; 13-Demethyl-Sanguinarine; 13-Demethylsanguinarine; Demethylsanguinarine; Dihydrosanguinarine; N-Norsanguinarine; Norsanguinarine; 2,3



数据库引用编号

14 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(0)

BioCyc(0)

PlantCyc(0)

代谢反应

0 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

18 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：

  • PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。

亚细胞结构定位 关联基因列表


文献列表

  • Liang Jiang, Xiaolu Wang, Yuting Wang, Fang Xu, Zhang Zhang, Ke Ding, Xiaoyun Lu. The synthesis and biological evaluation of sanguinarine derivatives as anti-non-small cell lung cancer agents. RSC medicinal chemistry. 2020 Feb; 11(2):293-296. doi: 10.1039/c9md00494g. [PMID: 33479636]
  • Phurpa Wangchuk, Wangchuk Phurpa, Paul A Keller, Stephen G Pyne, Wilford Lie, Anthony C Willis, Roonglawan Rattanajak, Sumalee Kamchonwongpaisan. A new protoberberine alkaloid from Meconopsis simplicifolia (D. Don) Walpers with potent antimalarial activity against a multidrug resistant Plasmodium falciparum strain. Journal of ethnopharmacology. 2013 Dec; 150(3):953-9. doi: 10.1016/j.jep.2013.09.052. [PMID: 24120516]
  • S Singh, L Jain, M B Pandey, U P Singh, V B Pandey. Antifungal activity of the alkaloids from Eschscholzia californica. Folia microbiologica. 2009; 54(3):204-6. doi: 10.1007/s12223-009-0032-7. [PMID: 19649736]
  • Xiao-ya Shang, Jian-gong Shi, Yong-chun Yang, Xing Liu, Chong Li, Cheng-zhong Zhang. [Alkaloids from a Tibetan medicine Meconopsis quintuplinervia Regel]. Yao xue xue bao = Acta pharmaceutica Sinica. 2003 Apr; 38(4):276-8. doi: ". [PMID: 12889127]