(1R)-3,5,5-Trimethyl-4-[3,7,12,16-tetramethyl-18-(2,6,6-trimethylcyclohexen-1-yl)octadeca-1,3,5,7,9,11,13,15,17-nonaenyl]cyclohex-3-en-1-ol (BioDeep_00000171595)

   

human metabolite blood metabolite


代谢物信息卡片


3,5,5-trimethyl-4-[3,7,12,16-tetramethyl-18-(2,6,6-trimethylcyclohex-1-en-1-yl)octadeca-1,3,5,7,9,11,13,15,17-nonaen-1-yl]cyclohex-3-en-1-ol

化学式: C40H56O (552.4331)
中文名称:
谱图信息: 最多检出来源 () 0%

分子结构信息

SMILES: CC(C=CC=C(C)C=CC1=C(C)CCCC1(C)C)=CC=CC=C(C)C=CC=C(C)C=CC1=C(C)CC(O)CC1(C)C
InChI: InChI=1S/C40H56O/c1-30(18-13-20-32(3)23-25-37-34(5)22-15-27-39(37,7)8)16-11-12-17-31(2)19-14-21-33(4)24-26-38-35(6)28-36(41)29-40(38,9)10/h11-14,16-21,23-26,36,41H,15,22,27-29H2,1-10H3



数据库引用编号

3 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(0)

BioCyc(0)

PlantCyc(0)

代谢反应

0 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

15 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有:

  • PubMed: 来源于PubMed文献库中的文献信息,我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表,这个列表按照代谢物同时出现的文献数量降序排序,取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘,得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序,取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中,存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称,可以跳转到相关代谢物的信息页面。

亚细胞结构定位 关联基因列表


文献列表

  • Atsushi Kimura, Yo-Han Kim, Kazuyoshi Hashizume, Akira Ito, Katsuyuki Mukai, Keiichiro Kizaki, Shigeru Sato. Single oral β-cryptoxanthin administration increases its serum concentration and enhances peripheral blood neutrophil function in Holstein cattle. The Journal of veterinary medical science. 2021 May; 83(5):829-831. doi: 10.1292/jvms.21-0054. [PMID: 33775992]
  • Shan Li, Xianglu Zhu, Lin Zhu, Xin Hu, Shujuan Wen. Associations between serum carotenoid levels and the risk of non-Hodgkin lymphoma: a case-control study. The British journal of nutrition. 2020 12; 124(12):1311-1319. doi: 10.1017/s000711452000152x. [PMID: 32349798]
  • Jean Fidèle Bationo, Augustin N Zeba, Souheila Abbeddou, Nadine D Coulibaly, Olivier O Sombier, Jesse Sheftel, Imael Henri Nestor Bassole, Nicolas Barro, Jean Bosco Ouedraogo, Sherry A Tanumihardjo. Serum Carotenoids Reveal Poor Fruit and Vegetable Intake among Schoolchildren in Burkina Faso. Nutrients. 2018 Oct; 10(10):. doi: 10.3390/nu10101422. [PMID: 30287727]
  • Jing Huang, Min-Shan Lu, Yu-Jing Fang, Ming Xu, Wu-Qing Huang, Zhi-Zhong Pan, Yu-Ming Chen, Cai-Xia Zhang. Serum carotenoids and colorectal cancer risk: A case-control study in Guangdong, China. Molecular nutrition & food research. 2017 10; 61(10):. doi: 10.1002/mnfr.201700267. [PMID: 28605127]
  • Anine Christine Medin, Monica Hauger Carlsen, Lene Frost Andersen. Associations between reported intakes of carotenoid-rich foods and concentrations of carotenoids in plasma: a validation study of a web-based food recall for children and adolescents. Public health nutrition. 2016 12; 19(18):3265-3275. doi: 10.1017/s1368980016001622. [PMID: 27346293]
  • Minoru Sugiura, Mieko Nakamura, Kazunori Ogawa, Yoshinori Ikoma, Masamichi Yano. High serum carotenoids associated with lower risk for the metabolic syndrome and its components among Japanese subjects: Mikkabi cohort study. The British journal of nutrition. 2015 Nov; 114(10):1674-82. doi: 10.1017/s0007114515003268. [PMID: 26365147]
  • Won Jin Ho, Michael S Simon, Vedat O Yildiz, James M Shikany, Ikuko Kato, Jennifer L Beebe-Dimmer, Jeremy P Cetnar, Cathryn H Bock. Antioxidant micronutrients and the risk of renal cell carcinoma in the Women's Health Initiative cohort. Cancer. 2015 Feb; 121(4):580-8. doi: 10.1002/cncr.29091. [PMID: 25302685]
  • Akihiko Nagao, Takashi Maoka, Hiroshi Ono, Eiichi Kotake-Nara, Miyuki Kobayashi, Mie Tomita. A 3-hydroxy β-end group in xanthophylls is preferentially oxidized to a 3-oxo ε-end group in mammals. Journal of lipid research. 2015 Feb; 56(2):449-62. doi: 10.1194/jlr.p055459. [PMID: 25502844]
  • Minoru Sugiura. [β-Cryptoxanthin and the risk for lifestyle-related disease: findings from recent nutritional epidemiologic studies]. Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan. 2015; 135(1):67-76. doi: 10.1248/yakushi.14-00208-5. [PMID: 25743900]
  • Marie Modestine Kana-Sop, Inocent Gouado, Mercy Bih Achu, John Van Camp, Paul Henri Amvam Zollo, Florian J Schweigert, Donald Oberleas, Tetanye Ekoe. The Influence of Iron and Zinc Supplementation on the Bioavailability of Provitamin A Carotenoids from Papaya Following Consumption of a Vitamin A-Deficient Diet. Journal of nutritional science and vitaminology. 2015; 61(3):205-14. doi: 10.3177/jnsv.61.205. [PMID: 26226956]
  • Kiyoko Nagahama, Nozomu Eto, Tomofumi Shimojo, Tomomi Kondoh, Keiko Nakahara, Yoichi Sakakibara, Keiichi Fukui, Masahito Suiko. Effect of kumquat (Fortunella crassifolia) pericarp on natural killer cell activity in vitro and in vivo. Bioscience, biotechnology, and biochemistry. 2015; 79(8):1327-36. doi: 10.1080/09168451.2015.1025033. [PMID: 25849817]
  • Huei-Yan Chen, Chih-Min Yang, Jen-Yin Chen, Te-Cheng Yueh, Miao-Lin Hu. Multicarotenoids at Physiological Levels Inhibit Metastasis in Human Hepatocarcinoma SK-Hep-1 Cells. Nutrition and cancer. 2015; 67(4):676-86. doi: 10.1080/01635581.2015.1019633. [PMID: 25868689]
  • Jun Liu, Wen-Qi Shi, Yi Cao, Li-Ping He, Ke Guan, Wen-Hua Ling, Yu-Ming Chen. Higher serum carotenoid concentrations associated with a lower prevalence of the metabolic syndrome in middle-aged and elderly Chinese adults. The British journal of nutrition. 2014 Dec; 112(12):2041-8. doi: 10.1017/s000711451400316x. [PMID: 25345663]
  • Jun S Lai, John Attia, Mark McEvoy, Alexis J Hure. Biochemical validation of the older Australian's food frequency questionnaire using carotenoids and vitamin E. Nutrients. 2014 Nov; 6(11):4906-17. doi: 10.3390/nu6114906. [PMID: 25383938]
  • F Granado-Lorencio, M J Lagarda, F J Garcia-López, L M Sánchez-Siles, I Blanco-Navarro, A Alegría, B Pérez-Sacristán, G Garcia-Llatas, E Donoso-Navarro, R A Silvestre-Mardomingo, R Barberá. Effect of β-cryptoxanthin plus phytosterols on cardiovascular risk and bone turnover markers in post-menopausal women: a randomized crossover trial. Nutrition, metabolism, and cardiovascular diseases : NMCD. 2014 Oct; 24(10):1090-6. doi: 10.1016/j.numecd.2014.04.013. [PMID: 24909799]
  • May A Beydoun, Michael A Nalls, J Atilio Canas, Michele K Evans, Alan B Zonderman. Gene polymorphisms and gene scores linked to low serum carotenoid status and their associations with metabolic disturbance and depressive symptoms in African-American adults. The British journal of nutrition. 2014 Sep; 112(6):992-1003. doi: 10.1017/s0007114514001706. [PMID: 25201307]
  • Elisabeth Kvaavik, Torunn H Totland, Nasser Bastani, Marte K Kjøllesdal, Grethe S Tell, Lene F Andersen. Do smoking and fruit and vegetable intake mediate the association between socio-economic status and plasma carotenoids?. European journal of public health. 2014 Aug; 24(4):685-90. doi: 10.1093/eurpub/ckt081. [PMID: 23813714]
  • Kyoung-Bok Min, Jin-Young Min. Serum carotenoid levels and risk of lung cancer death in US adults. Cancer science. 2014 Jun; 105(6):736-43. doi: 10.1111/cas.12405. [PMID: 24673770]
  • Michael R La Frano, Chenghao Zhu, Betty J Burri. Assessment of tissue distribution and concentration of β-cryptoxanthin in response to varying amounts of dietary β-cryptoxanthin in the Mongolian gerbil. The British journal of nutrition. 2014 Mar; 111(6):968-78. doi: 10.1017/s0007114513003371. [PMID: 24229567]
  • Soroush Ghodratizadeh, Güngör Kanbak, Mojtaba Beyramzadeh, Zeliha Gunnur Dikmen, Salar Memarzadeh, Reza Habibian. Effect of carotenoid β-cryptoxanthin on cellular and humoral immune response in rabbit. Veterinary research communications. 2014 Mar; 38(1):59-62. doi: 10.1007/s11259-013-9584-8. [PMID: 24307458]
  • Meng Yang, Ying Wang, Catherine G Davis, Sang Gil Lee, Maria Luz Fernandez, Sung I Koo, Eunyoung Cho, Won O Song, Ock K Chun. Validation of an FFQ to assess short-term antioxidant intake against 30 d food records and plasma biomarkers. Public health nutrition. 2014 Feb; 17(2):297-306. doi: 10.1017/s1368980012005071. [PMID: 23164175]
  • Camille Pouchieu, Pilar Galan, Véronique Ducros, Paule Latino-Martel, Serge Hercberg, Mathilde Touvier. Plasma carotenoids and retinol and overall and breast cancer risk: a nested case-control study. Nutrition and cancer. 2014; 66(6):980-8. doi: 10.1080/01635581.2014.936952. [PMID: 25072980]
  • Andrew P Black, Hassan Vally, Peter Morris, Mark Daniel, Adrian Esterman, Connie S Karschimkus, Kerin O'Dea. Nutritional impacts of a fruit and vegetable subsidy programme for disadvantaged Australian Aboriginal children. The British journal of nutrition. 2013 Dec; 110(12):2309-17. doi: 10.1017/s0007114513001700. [PMID: 23742751]
  • Tami Turner, Betty J Burri, Kazi M Jamil, Maleka Jamil. The effects of daily consumption of β-cryptoxanthin-rich tangerines and β-carotene-rich sweet potatoes on vitamin A and carotenoid concentrations in plasma and breast milk of Bangladeshi women with low vitamin A status in a randomized controlled trial. The American journal of clinical nutrition. 2013 Nov; 98(5):1200-8. doi: 10.3945/ajcn.113.058180. [PMID: 24004891]
  • Sara J Hendrickson, Walter C Willett, Bernard A Rosner, A Heather Eliassen. Food predictors of plasma carotenoids. Nutrients. 2013 Oct; 5(10):4051-66. doi: 10.3390/nu5104051. [PMID: 24152746]
  • Rachel E Kopec, Ralf M Schweiggert, Ken M Riedl, Reinhold Carle, Steven J Schwartz. Comparison of high-performance liquid chromatography/tandem mass spectrometry and high-performance liquid chromatography/photo-diode array detection for the quantitation of carotenoids, retinyl esters, α-tocopherol and phylloquinone in chylomicron-rich fractions of human plasma. Rapid communications in mass spectrometry : RCM. 2013 Jun; 27(12):1393-402. doi: 10.1002/rcm.6576. [PMID: 23681818]
  • D Kevin Horton, Olorunfemi Adetona, Manuel Aguilar-Villalobos, Brandon E Cassidy, Christine M Pfeiffer, Rosemary L Schleicher, Kathleen L Caldwell, Larry L Needham, Stephen L Rathbun, John E Vena, Luke P Naeher. Changes in the concentrations of biochemical indicators of diet and nutritional status of pregnant women across pregnancy trimesters in Trujillo, Peru, 2004-2005. Nutrition journal. 2013 Jun; 12(?):80. doi: 10.1186/1475-2891-12-80. [PMID: 23758715]
  • Stephanie M Rink, Pauline Mendola, Sunni L Mumford, Jill K Poudrier, Richard W Browne, Jean Wactawski-Wende, Neil J Perkins, Enrique F Schisterman. Self-report of fruit and vegetable intake that meets the 5 a day recommendation is associated with reduced levels of oxidative stress biomarkers and increased levels of antioxidant defense in premenopausal women. Journal of the Academy of Nutrition and Dietetics. 2013 Jun; 113(6):776-85. doi: 10.1016/j.jand.2013.01.019. [PMID: 23522825]
  • Patrick Borel, Georg Lietz, Aurélie Goncalves, Fabien Szabo de Edelenyi, Sophie Lecompte, Peter Curtis, Louisa Goumidi, Muriel J Caslake, Elizabeth A Miles, Christopher Packard, Philip C Calder, John C Mathers, Anne M Minihane, Franck Tourniaire, Emmanuelle Kesse-Guyot, Pilar Galan, Serge Hercberg, Christina Breidenassel, Marcela González Gross, Myriam Moussa, Aline Meirhaeghe, Emmanuelle Reboul. CD36 and SR-BI are involved in cellular uptake of provitamin A carotenoids by Caco-2 and HEK cells, and some of their genetic variants are associated with plasma concentrations of these micronutrients in humans. The Journal of nutrition. 2013 Apr; 143(4):448-56. doi: 10.3945/jn.112.172734. [PMID: 23427331]
  • Brian J Song, Zeina E Jouni, Mario G Ferruzzi. Assessment of phytochemical content in human milk during different stages of lactation. Nutrition (Burbank, Los Angeles County, Calif.). 2013 Jan; 29(1):195-202. doi: 10.1016/j.nut.2012.07.015. [PMID: 23237648]
  • Ying Wang, Meng Yang, Sang-Gil Lee, Catherine G Davis, Anne Kenny, Sung I Koo, Ock K Chun. Plasma total antioxidant capacity is associated with dietary intake and plasma level of antioxidants in postmenopausal women. The Journal of nutritional biochemistry. 2012 Dec; 23(12):1725-31. doi: 10.1016/j.jnutbio.2011.12.004. [PMID: 22617460]
  • Kaye E Brock, Liang Ke, Gloria Gridley, Brian C-H Chiu, Abby G Ershow, Charles F Lynch, Barry I Graubard, Kenneth P Cantor. Fruit, vegetables, fibre and micronutrients and risk of US renal cell carcinoma. The British journal of nutrition. 2012 Sep; 108(6):1077-85. doi: 10.1017/s0007114511006489. [PMID: 22186835]
  • Francina R Baldrick, J Stuart Elborn, Jayne V Woodside, Katherine Treacy, Judy M Bradley, Chris C Patterson, Bettina C Schock, Madeleine Ennis, Ian S Young, Michelle C McKinley. Effect of fruit and vegetable intake on oxidative stress and inflammation in COPD: a randomised controlled trial. The European respiratory journal. 2012 Jun; 39(6):1377-84. doi: 10.1183/09031936.00086011. [PMID: 22088966]
  • Masako Iwamoto, Katsumi Imai, Hideaki Ohta, Bungo Shirouchi, Masao Sato. Supplementation of highly concentrated β-cryptoxanthin in a satsuma mandarin beverage improves adipocytokine profiles in obese Japanese women. Lipids in health and disease. 2012 May; 11(?):52. doi: 10.1186/1476-511x-11-52. [PMID: 22584034]
  • Ping Fan, Yao Shen, Yonghua Li, Aiqin Ma, Zhongqing Sun, Zhixu Wang. [Serum retinol and carotenoid of rural infants and young children in Linyi of Shangdong Province and analysis on their related influencing dietary factors]. Wei sheng yan jiu = Journal of hygiene research. 2012 May; 41(3):424-8. doi: NULL. [PMID: 23050441]
  • R D Semba, S S Chang, K Sun, S Talegawkar, L Ferrucci, L P Fried. Serum carotenoids and pulmonary function in older community-dwelling women. The journal of nutrition, health & aging. 2012 Apr; 16(4):291-6. doi: 10.1007/s12603-012-0034-z. [PMID: 22499445]
  • Masahiro Sato, Atsushi Hozawa, Tsuneo Konta, Li Shao, Katsumi Otani, Hiroto Narimatsu, Satoshi Sasaki, Takeo Kato, Isao Kubota, Hidetoshi Yamashita, Takamasa Kayama, Akira Fukao. Relationship between dietary intake and microalbuminuria: findings from the Takahata study. Clinical and experimental nephrology. 2012 Feb; 16(1):147-55. doi: 10.1007/s10157-011-0539-5. [PMID: 21964760]
  • Frederick Khachik. Partial synthesis of serum carotenoids and their metabolites. Acta biochimica Polonica. 2012; 59(1):75-8. doi: . [PMID: 22428147]
  • Naoki Takaishi, Hideo Satsu, Katsuhiko Takayanagi, Katsuyuki Mukai, Makoto Shimizu. In vivo and in vitro studies on the absorption characteristics of β-cryptoxanthin in the intestine. Bioscience, biotechnology, and biochemistry. 2012; 76(11):2124-8. doi: 10.1271/bbb.120511. [PMID: 23132588]
  • Cara L Frankenfeld, Johanna W Lampe, Jackilen Shannon, Dao L Gao, Wenjin Li, Roberta M Ray, Chu Chen, Irena B King, David B Thomas. Fruit and vegetable intakes in relation to plasma nutrient concentrations in women in Shanghai, China. Public health nutrition. 2012 Jan; 15(1):167-75. doi: 10.1017/s1368980011001029. [PMID: 21729475]
  • Eugene Shim, Kyung-Jin Yeum, Guangwen Tang, Sei Hyun Ahn, Jinah Hwang, Yang Cha Lee-Kim. Retinoids, carotenoids, and tocopherols in breast adipose tissue and serum of benign breast disease and breast cancer patients. Nutrition and cancer. 2012; 64(7):956-63. doi: 10.1080/01635581.2012.717678. [PMID: 23061903]
  • Shiro Imagama, Yukiharu Hasegawa, Taisuke Seki, Yukihiro Matsuyama, Yoshihito Sakai, Zenya Ito, Naoki Ishiguro, Yoshinori Ito, Nobuyuki Hamajima, Koji Suzuki. The effect of β-carotene on lumbar osteophyte formation. Spine. 2011 Dec; 36(26):2293-8. doi: 10.1097/brs.0b013e3182254a18. [PMID: 21673632]
  • Fernando Granado-Lorencio, Encarnación Donoso-Navarro, Luis Manuel Sánchez-Siles, Inmaculada Blanco-Navarro, Belen Pérez-Sacristán. Bioavailability of β-cryptoxanthin in the presence of phytosterols: in vitro and in vivo studies. Journal of agricultural and food chemistry. 2011 Nov; 59(21):11819-24. doi: 10.1021/jf202628w. [PMID: 21954852]
  • Kultida Klarod, Pranithi Hongsprabhas, Tueanjit Khampitak, Kosin Wirasorn, Sasisopin Kiertiburanakul, Roongpet Tangrassameeprasert, Jureerut Daduang, Puangrat Yongvanit, Patcharee Boonsiri. Serum antioxidant levels and nutritional status in early and advanced stage lung cancer patients. Nutrition (Burbank, Los Angeles County, Calif.). 2011 Nov; 27(11-12):1156-60. doi: 10.1016/j.nut.2010.12.019. [PMID: 21530173]
  • Zhixu Wang, Huizhen Zhang, Min Liu, Dong Su, Xinna Song, Jianqiang Lai. [Serum carotenoid concentrations in some Chinese adults from urban, suburban and rural communities]. Wei sheng yan jiu = Journal of hygiene research. 2011 Sep; 40(5):591-5. doi: NULL. [PMID: 22043709]
  • Chun Liu, Roderick T Bronson, Robert M Russell, Xiang-Dong Wang. β-Cryptoxanthin supplementation prevents cigarette smoke-induced lung inflammation, oxidative damage, and squamous metaplasia in ferrets. Cancer prevention research (Philadelphia, Pa.). 2011 Aug; 4(8):1255-66. doi: 10.1158/1940-6207.capr-10-0384. [PMID: 21421799]
  • Alexandra M Johnstone, Gerald E Lobley, Graham W Horgan, David M Bremner, Claire L Fyfe, Philip C Morrice, Garry G Duthie. Effects of a high-protein, low-carbohydrate v. high-protein, moderate-carbohydrate weight-loss diet on antioxidant status, endothelial markers and plasma indices of the cardiometabolic profile. The British journal of nutrition. 2011 Jul; 106(2):282-91. doi: 10.1017/s0007114511000092. [PMID: 21521539]
  • Koji Suzuki, Yoshinori Ito, Takashi Inoue, Nobuyuki Hamajima. Inverse association of serum carotenoids with prevalence of metabolic syndrome among Japanese. Clinical nutrition (Edinburgh, Scotland). 2011 Jun; 30(3):369-75. doi: 10.1016/j.clnu.2010.12.006. [PMID: 21216053]
  • Ryoichi Izuchi, Yuji Nakai, Hidehito Takahashi, Shota Ushiama, Shinji Okada, Takumi Misaka, Keiko Abe. Hepatic gene expression of the insulin signaling pathway is altered by administration of persimmon peel extract: a DNA microarray study using type 2 diabetic Goto-Kakizaki rats. Journal of agricultural and food chemistry. 2011 Apr; 59(7):3320-9. doi: 10.1021/jf102422z. [PMID: 21370910]
  • Michelle D Shardell, Dawn E Alley, Gregory E Hicks, Samer S El-Kamary, Ram R Miller, Richard D Semba, Luigi Ferrucci. Low-serum carotenoid concentrations and carotenoid interactions predict mortality in US adults: the Third National Health and Nutrition Examination Survey. Nutrition research (New York, N.Y.). 2011 Mar; 31(3):178-89. doi: 10.1016/j.nutres.2011.03.003. [PMID: 21481711]
  • Masahito Tanaka, Yuko Kamiya, Tomoyuki Suzuki, Yutaka Nakai. Effect of citrus pulp silage feeding on concentration of beta-cryptoxanthin in plasma and milk of dairy cows. Animal science journal = Nihon chikusan Gakkaiho. 2010 Oct; 81(5):569-73. doi: 10.1111/j.1740-0929.2010.00775.x. [PMID: 20887309]
  • Gerard J Linden, Kathy M McClean, Jayne V Woodside, Chris C Patterson, Alun Evans, Ian S Young, Frank Kee. Antioxidants and periodontitis in 60-70-year-old men. Journal of clinical periodontology. 2009 Oct; 36(10):843-9. doi: 10.1111/j.1600-051x.2009.01468.x. [PMID: 19703237]
  • F Granado-Lorencio, C Herrero-Barbudo, B Olmedilla-Alonso, I Blanco-Navarro, B Pérez-Sacristán. Hypocarotenemia after bariatric surgery: a preliminary study. Obesity surgery. 2009 Jul; 19(7):879-82. doi: 10.1007/s11695-008-9476-0. [PMID: 18369683]
  • M R Forman, C B Borkowf, M M Cantwell, S Steck, A Schatzkin, P S Albert, E Lanza. Components of variation in serum carotenoid concentrations: the Polyp Prevention Trial. European journal of clinical nutrition. 2009 Jun; 63(6):763-70. doi: 10.1038/ejcn.2008.26. [PMID: 18414504]
  • A M B Priyadarshani, Sanath P Lamabadusuriya, T R S Seneviratne, E R Jansz, H Peiris. A study of the serum carotenoids of eight cases of hypercarotenemia in Sri Lanka. International journal of food sciences and nutrition. 2009 Jun; 60(4):352-7. doi: 10.1080/09637480801992484. [PMID: 18651297]
  • Masayuki Okuda, Satoshi Sasaki, Noriko Bando, Michio Hashimoto, Ichiro Kunitsugu, Shinichi Sugiyama, Junji Terao, Tatsuya Hobara. Carotenoid, tocopherol, and fatty acid biomarkers and dietary intake estimated by using a brief self-administered diet history questionnaire for older Japanese children and adolescents. Journal of nutritional science and vitaminology. 2009 Jun; 55(3):231-41. doi: 10.3177/jnsv.55.231. [PMID: 19602831]
  • Yolanda Lorenzo, Amaia Azqueta, Luisa Luna, Félix Bonilla, Gemma Domínguez, Andrew R Collins. The carotenoid beta-cryptoxanthin stimulates the repair of DNA oxidation damage in addition to acting as an antioxidant in human cells. Carcinogenesis. 2009 Feb; 30(2):308-14. doi: 10.1093/carcin/bgn270. [PMID: 19056931]
  • Laima Brazionis, Kevin Rowley, Catherine Itsiopoulos, Kerin O'Dea. Plasma carotenoids and diabetic retinopathy. The British journal of nutrition. 2009 Jan; 101(2):270-7. doi: 10.1017/s0007114508006545. [PMID: 18554424]
  • Minoru Sugiura, Mieko Nakamura, Kazunori Ogawa, Yoshinori Ikoma, Hikaru Matsumoto, Fujiko Ando, Hiroshi Shimokata, Masamichi Yano. Associations of serum carotenoid concentrations with the metabolic syndrome: interaction with smoking. The British journal of nutrition. 2008 Dec; 100(6):1297-306. doi: 10.1017/s0007114508978302. [PMID: 18445303]
  • Wildon R Farwell, J Michael Gaziano, Edward P Norkus, Howard D Sesso. The relationship between total plasma carotenoids and risk factors for chronic disease among middle-aged and older men. The British journal of nutrition. 2008 Oct; 100(4):883-9. doi: 10.1017/s0007114508944111. [PMID: 18334043]
  • Sameera A Talegawkar, Elizabeth J Johnson, Teresa C Carithers, Herman A Taylor, Margaret L Bogle, Katherine L Tucker. Carotenoid intakes, assessed by food-frequency questionnaires (FFQs), are associated with serum carotenoid concentrations in the Jackson Heart Study: validation of the Jackson Heart Study Delta NIRI Adult FFQs. Public health nutrition. 2008 Oct; 11(10):989-97. doi: 10.1017/s1368980007001310. [PMID: 18053294]
  • Zhifang Yang, Zhumin Zhang, Kristina L Penniston, Neil Binkley, Sherry A Tanumihardjo. Serum carotenoid concentrations in postmenopausal women from the United States with and without osteoporosis. International journal for vitamin and nutrition research. Internationale Zeitschrift fur Vitamin- und Ernahrungsforschung. Journal international de vitaminologie et de nutrition. 2008 May; 78(3):105-11. doi: 10.1024/0300-9831.78.3.105. [PMID: 19003732]
  • F Granado-Lorencio, B Olmedilla-Alonso, C Herrero-Barbudo, I Blanco-Navarro, B Pérez-Sacristán. Seasonal variation of serum alpha- and beta-cryptoxanthin and 25-OH-vitamin D(3) in women with osteoporosis. Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA. 2008 May; 19(5):717-20. doi: 10.1007/s00198-007-0470-5. [PMID: 17882465]
  • M Sugiura, M Nakamura, K Ogawa, Y Ikoma, F Ando, M Yano. Bone mineral density in post-menopausal female subjects is associated with serum antioxidant carotenoids. Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA. 2008 Feb; 19(2):211-9. doi: 10.1007/s00198-007-0457-2. [PMID: 17846860]
  • Zora Djuric, David L Ronis, Karen E Fowler, Jianwei Ren, Sonia A Duffy. Levels of fat-soluble micronutrients and 2,6-cyclolycopene-1,5-diol in head and neck cancer patients. International journal for vitamin and nutrition research. Internationale Zeitschrift fur Vitamin- und Ernahrungsforschung. Journal international de vitaminologie et de nutrition. 2007 Nov; 77(6):382-8. doi: 10.1024/0300-9831.77.6.382. [PMID: 18622948]
  • Jim P Stimpson, Anita C Nash, Hyunsu Ju, Karl Eschbach. Neighborhood Deprivation is associated with lower levels of serum carotenoids among adults participating in the Third National Health and Nutrition Examination Survey. Journal of the American Dietetic Association. 2007 Nov; 107(11):1895-902. doi: 10.1016/j.jada.2007.08.016. [PMID: 17964308]
  • Jim P Stimpson, Nuha A Lackan. Serum carotenoid levels vary by marital status. Journal of the American Dietetic Association. 2007 Sep; 107(9):1581-5. doi: 10.1016/j.jada.2007.06.007. [PMID: 17761235]
  • Jim P Stimpson, Ximena Urrutia-Rojas. Acculturation in the United States is associated with lower serum carotenoid levels: Third National Health and Nutrition Examination Survey. Journal of the American Dietetic Association. 2007 Jul; 107(7):1218-23. doi: 10.1016/j.jada.2007.04.008. [PMID: 17604755]
  • Caroline Lidebjer, Per Leanderson, Jan Ernerudh, Lena Jonasson. Low plasma levels of oxygenated carotenoids in patients with coronary artery disease. Nutrition, metabolism, and cardiovascular diseases : NMCD. 2007 Jul; 17(6):448-56. doi: 10.1016/j.numecd.2006.02.006. [PMID: 17134954]
  • Jesús Vioque, Tanja Weinbrenner, Laura Asensio, Adela Castelló, Ian S Young, Astrid Fletcher. Plasma concentrations of carotenoids and vitamin C are better correlated with dietary intake in normal weight than overweight and obese elderly subjects. The British journal of nutrition. 2007 May; 97(5):977-86. doi: 10.1017/s0007114507659017. [PMID: 17408529]
  • N Tasnime Akbaraly, Henri Faure, Veronique Gourlet, Alain Favier, Claudine Berr. Plasma carotenoid levels and cognitive performance in an elderly population: results of the EVA Study. The journals of gerontology. Series A, Biological sciences and medical sciences. 2007 Mar; 62(3):308-16. doi: 10.1093/gerona/62.3.308. [PMID: 17389729]
  • Dietmar E Breithaupt, Elhadi M Yahia, Francisco J Valdés Velázquez. Comparison of the absorption efficiency of alpha- and beta-cryptoxanthin in female Wistar rats. The British journal of nutrition. 2007 Feb; 97(2):329-36. doi: 10.1017/s0007114507336751. [PMID: 17298702]
  • Daniel O Stram, Jian-Min Yuan, Kenneth K Chan, Yu-Tang Gao, Ronald K Ross, Mimi C Yu. Beta-cryptoxanthin and lung cancer in Shanghai, China--an examination of potential confounding with cigarette smoking using urinary cotinine as a biomarker for true tobacco exposure. Nutrition and cancer. 2007; 57(2):123-9. doi: 10.1080/01635580701273998. [PMID: 17571944]
  • Yu-Ju Lin, Yi-Wen Chien, Shwu-Huey Yang, Hsing-Hsien Cheng. Fruits and stir-fried vegetables increase plasma carotenoids in young adults. Asia Pacific journal of clinical nutrition. 2007; 16(4):616-23. doi: NULL. [PMID: 18042520]
  • Jianjun Zhang, Ishwori Dhakal, Angie Stone, Baitang Ning, Graham Greene, Nicholas P Lang, Fred F Kadlubar. Plasma carotenoids and prostate cancer: a population-based case-control study in Arkansas. Nutrition and cancer. 2007; 59(1):46-53. doi: 10.1080/01635580701385900. [PMID: 17927501]
  • John P Pierce, Loki Natarajan, Shelly Sun, Wael Al-Delaimy, Shirley W Flatt, Sheila Kealey, Cheryl L Rock, Cynthia A Thomson, Vicky A Newman, Cheryl Ritenbaugh, Ellen B Gold, Bette J Caan. Increases in plasma carotenoid concentrations in response to a major dietary change in the women's healthy eating and living study. Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology. 2006 Oct; 15(10):1886-92. doi: 10.1158/1055-9965.epi-05-0928. [PMID: 17035395]
  • Lu Wang, Simin Liu, Aruna D Pradhan, Joann E Manson, Julie E Buring, J Michael Gaziano, Howard D Sesso. Plasma lycopene, other carotenoids, and the risk of type 2 diabetes in women. American journal of epidemiology. 2006 Sep; 164(6):576-85. doi: 10.1093/aje/kwj240. [PMID: 16801375]
  • Jörg Schlatterer, Dietmar E Breithaupt, Maike Wolters, Andreas Hahn. Plasma responses in human subjects after ingestions of multiple doses of natural alpha-cryptoxanthin: a pilot study. The British journal of nutrition. 2006 Aug; 96(2):371-6. doi: 10.1079/bjn20061848. [PMID: 16923233]
  • Atsushi Hozawa, David R Jacobs, Michael W Steffes, Myron D Gross, Lyn M Steffen, Duk-Hee Lee. Associations of serum carotenoid concentrations with the development of diabetes and with insulin concentration: interaction with smoking: the Coronary Artery Risk Development in Young Adults (CARDIA) Study. American journal of epidemiology. 2006 May; 163(10):929-37. doi: 10.1093/aje/kwj136. [PMID: 16597706]
  • Jian-Min Yuan, Yu-Tang Gao, Choon-Nam Ong, Ronald K Ross, Mimi C Yu. Prediagnostic level of serum retinol in relation to reduced risk of hepatocellular carcinoma. Journal of the National Cancer Institute. 2006 Apr; 98(7):482-90. doi: 10.1093/jnci/djj104. [PMID: 16595784]
  • Mieko Nakamura, Minoru Sugiura, Nobuo Aoki. High beta-carotene and beta-cryptoxanthin are associated with low pulse wave velocity. Atherosclerosis. 2006 Feb; 184(2):363-9. doi: 10.1016/j.atherosclerosis.2005.04.006. [PMID: 15936762]
  • Isabella Sundl, Elisabeth Pail, Karin Mellitzer, Hermann Toplak, Brigitte M Winklhofer-Roob. Effects of orlistat therapy on plasma concentrations of oxygenated and hydrocarbon carotenoids. Lipids. 2006 Feb; 41(2):113-8. doi: 10.1007/s11745-006-5078-6. [PMID: 17707976]
  • Minoru Sugiura, Mieko Nakamura, Yoshinori Ikoma, Masamichi Yano, Kazunori Ogawa, Hikaru Matsumoto, Masaya Kato, Makoto Ohshima, Akihiko Nagao. Serum carotenoid concentrations are inversely associated with serum aminotransferases in hyperglycemic subjects. Diabetes research and clinical practice. 2006 Jan; 71(1):82-91. doi: 10.1016/j.diabres.2005.05.004. [PMID: 16005096]
  • W K Al-Delaimy, P Ferrari, N Slimani, V Pala, I Johansson, S Nilsson, I Mattisson, E Wirfalt, R Galasso, D Palli, P Vineis, R Tumino, M Dorronsoro, G Pera, M C Ocké, H B Bueno-de-Mesquita, K Overvad, Mad Chirlaque, A Trichopoulou, A Naska, A Tjønneland, A Olsen, E Lund, E H R Alsaker, A Barricarte, E Kesse, M-C Boutron-Ruault, F Clavel-Chapelon, T J Key, E Spencer, S Bingham, A A Welch, M-J Sanchez-Perez, G Nagel, J Linseisen, J R Quirós, P H M Peeters, C H van Gils, H Boeing, A L van Kappel, J-P Steghens, E Riboli. Plasma carotenoids as biomarkers of intake of fruits and vegetables: individual-level correlations in the European Prospective Investigation into Cancer and Nutrition (EPIC). European journal of clinical nutrition. 2005 Dec; 59(12):1387-96. doi: 10.1038/sj.ejcn.1602252. [PMID: 16160702]
  • Terry Coyne, Torukiri I Ibiebele, Peter D Baade, Annette Dobson, Christine McClintock, Sophie Dunn, Dympna Leonard, Jonathan Shaw. Diabetes mellitus and serum carotenoids: findings of a population-based study in Queensland, Australia. The American journal of clinical nutrition. 2005 Sep; 82(3):685-93. doi: 10.1093/ajcn.82.3.685. [PMID: 16155284]
  • Satoshi Uchiyama, Masayoshi Yamaguchi. Oral administration of beta-cryptoxanthin prevents bone loss in streptozotocin-diabetic rats in vivo. Biological & pharmaceutical bulletin. 2005 Sep; 28(9):1766-9. doi: 10.1248/bpb.28.1766. [PMID: 16141556]
  • Satoshi Uchiyama, Masayoshi Yamaguchi. beta-cryptoxanthin stimulates cell differentiation and mineralization in osteoblastic MC3T3-E1 cells. Journal of cellular biochemistry. 2005 Aug; 95(6):1224-34. doi: 10.1002/jcb.20496. [PMID: 15962303]
  • D M Clements, D A Oleesky, S C Smith, H Wheatley, D A Hullin, T J Havard, D J Bowrey. A study to determine plasma antioxidant concentrations in patients with Barrett's oesophagus. Journal of clinical pathology. 2005 May; 58(5):490-2. doi: 10.1136/jcp.2004.023721. [PMID: 15858119]
  • Shine Chang, John W Erdman, Steven K Clinton, Maya Vadiveloo, Sara S Strom, Yuko Yamamura, Cherie M Duphorne, Margaret R Spitz, Christopher I Amos, John H Contois, Xiangjun Gu, Richard J Babaian, Peter T Scardino, Stephen D Hursting. Relationship between plasma carotenoids and prostate cancer. Nutrition and cancer. 2005; 53(2):127-34. doi: 10.1207/s15327914nc5302_1. [PMID: 16573373]
  • Minoru Sugiura, Hikaru Matsumoto, Masaya Kato, Yoshinori Ikoma, Masamichi Yano, Akihiko Nagao. Seasonal changes in the relationship between serum concentration of beta-cryptoxanthin and serum lipid levels. Journal of nutritional science and vitaminology. 2004 Dec; 50(6):410-5. doi: 10.3177/jnsv.50.410. [PMID: 15895516]
  • Luc Dauchet, Jean Ferrières, Dominique Arveiler, John W Yarnell, Fred Gey, Pierre Ducimetière, Jean-Bernard Ruidavets, Bernadette Haas, Alun Evans, Annie Bingham, Philippe Amouyel, Jean Dallongeville. Frequency of fruit and vegetable consumption and coronary heart disease in France and Northern Ireland: the PRIME study. The British journal of nutrition. 2004 Dec; 92(6):963-72. doi: 10.1079/bjn20041286. [PMID: 15613259]
  • M C J F Jansen, A L Van Kappel, M C Ocké, P Van 't Veer, H C Boshuizen, E Riboli, H B Bueno-de-Mesquita. Plasma carotenoid levels in Dutch men and women, and the relation with vegetable and fruit consumption. European journal of clinical nutrition. 2004 Oct; 58(10):1386-95. doi: 10.1038/sj.ejcn.1601981. [PMID: 15054421]
  • Sabine Rohrmann, Ellen Smit, Edward Giovannucci, Elizabeth A Platz. Association between serum concentrations of micronutrients and lower urinary tract symptoms in older men in the Third National Health and Nutrition Examination Survey. Urology. 2004 Sep; 64(3):504-9. doi: 10.1016/j.urology.2004.04.012. [PMID: 15351580]
  • Judith M van der Horst-Graat, Frans J Kok, Evert G Schouten. Plasma carotenoid concentrations in relation to acute respiratory infections in elderly people. The British journal of nutrition. 2004 Jul; 92(1):113-8. doi: 10.1079/bjn20041155. [PMID: 15230994]
  • Minoru Sugiura, Hikaru Matsumoto, Masaya Kato, Yoshinori Ikoma, Masamichi Yano, Akihiko Nagao. Multiple linear regression analysis of the seasonal changes in the serum concentration of beta-cryptoxanthin. Journal of nutritional science and vitaminology. 2004 Jun; 50(3):196-202. doi: 10.3177/jnsv.50.196. [PMID: 15386932]
  • Christy C Tangney, Julia L Bienias, Denis A Evans, Martha C Morris. Reasonable estimates of serum vitamin E, vitamin C, and beta-cryptoxanthin are obtained with a food frequency questionnaire in older black and white adults. The Journal of nutrition. 2004 Apr; 134(4):927-34. doi: 10.1093/jn/134.4.927. [PMID: 15051849]
  • Masayoshi Yamaguchi, Satoshi Uchiyama. beta-Cryptoxanthin stimulates bone formation and inhibits bone resorption in tissue culture in vitro. Molecular and cellular biochemistry. 2004 Mar; 258(1-2):137-44. doi: 10.1023/b:mcbi.0000012848.50541.19. [PMID: 15030178]
  • Mohamad Navab, Srinivasa T Reddy, Brian J Van Lenten, Alan M Fogelman. Apparent paradox of low-fat 'healthy' diets increasing plasma levels of oxidized low-density lipoprotein and lipoprotein(a). Arteriosclerosis, thrombosis, and vascular biology. 2004 Mar; 24(3):392-3. doi: 10.1161/01.atv.0000118014.49565.fc. [PMID: 15003971]
  • Satoshi Uchiyama, Takashi Sumida, Masayoshi Yamaguchi. Oral administration of beta-cryptoxanthin induces anabolic effects on bone components in the femoral tissues of rats in vivo. Biological & pharmaceutical bulletin. 2004 Feb; 27(2):232-5. doi: 10.1248/bpb.27.232. [PMID: 14758041]