Chalcone (BioDeep_00000014477)

Main id: BioDeep_00000001116

 

human metabolite PANOMIX_OTCML-2023 PANOMIX-Anthocyanidin Antitumor activity natural product


代谢物信息卡片


phenyl (E)--2-phenylethenyl ketone

化学式: C15H12O (208.0888)
中文名称: 查尔酮, 查耳酮
谱图信息: 最多检出来源 () 0%

分子结构信息

SMILES: C1=CC=C(C=C1)C=CC(=O)C2=CC=CC=C2
InChI: InChI=1S/C15H12O/c16-15(14-9-5-2-6-10-14)12-11-13-7-3-1-4-8-13/h1-12H/b12-11+

描述信息

Chalcone is an aromatic ketone that forms the central core for a variety of important biological compounds, which are known collectively as chalcones. They show antibacterial, antifungal, antitumor and anti-inflammatory properties. They are also intermediates in the biosynthesis of flavonoids, which are substances widespread in plants and with an array of biological activities. Chalcones are also intermediates in the Auwers synthesis of flavones.Chalcones can be prepared by an aldol condensation between a benzaldehyde and an acetophenone in the presence of sodium hydroxide as a catalyst. This reaction has been found to work in without any solvent at all - a solid-state reaction. The reaction between substituted benzaldehydes and acetophenones has been used to demonstrate green chemistry in undergraduate chemistry education. In a study investigating green chemistry synthesis, chalcones were also synthesized from the same starting materials in high temperature water (200 to 350 degree centigrade).
Chalcone is an aromatic ketone that forms the central core for a variety of important biological compounds, which are known collectively as chalcones. They show antibacterial, antifungal, antitumor and anti-inflammatory properties. They are also intermediates in the biosynthesis of flavonoids, which are substances widespread in plants and with an array of biological activities. Chalcones are also intermediates in the Auwers synthesis of flavones.Chalcones can be prepared by an aldol condensation between a benzaldehyde and an acetophenone in the presence of sodium hydroxide as a catalyst.
Chalcone is isolated from Glycyrrhiza uralensis and used to synthesize chalcone derivatives. Chalcone derivatives possess varied biological and pharmacological activity, including anti-inflammatory, antioxidative, antibacterial, anticancer, and anti-parasitic activities[1].
Chalcone is isolated from Glycyrrhiza uralensis and used to synthesize chalcone derivatives. Chalcone derivatives possess varied biological and pharmacological activity, including anti-inflammatory, antioxidative, antibacterial, anticancer, and anti-parasitic activities[1].

同义名列表

41 个代谢物同义名

phenyl (E)--2-phenylethenyl ketone; (2E)-1,3-Diphenyl-2-propen-1-one; (2E)-1,3-diphenylprop-2-en-1-one; (E)-1,3-Diphenyl-2-propen-1-one; alpha-Benzylideneacetophenone; trans-Benzylideneacetophenone; 1, 3-Diphenyl-1-propen-3-one; (E)-Benzylideneacetophenone; Phenyl 2-phenylvinyl ketone; 1,3 Diphenyl 2 Propen 1 One; 1,3-Diphenyl-2-Propen-1-One; 1-Phenyl-2-benzoylethylene; 1-Benzoyl-2-phenylethylene; Phenyl trans-styryl ketone; 2-Benzylideneacetophenone; a-Benzylideneacetophenone; beta-Phenylacrylophenone; 1-Benzoyl-1-phenylethene; trans-Benzalacetophenone; 1-Benzoyl-2-phenylethene; 1,3-Diphenyl-2-propenone; Benzylideneacetophenone; chalcone (ACD/Name 4.0); Benzylidenecetophenone; 3-phenyl-Acrylophenone; 1,3-Diphenylpropenone; 3-Phenylacrylophenone; b-Phenylacrylophenone; Styryl phenyl ketone; 2-Benzalacetophenone; Phenyl styryl ketone; beta-Benzoylstyrene; Benzalacetophenone; b-Benzoylstyrene; trans-Chalcone; Cinnamophenone; (E)-Chalcone; Chalcone; Chalkone; Chalcone; Chalcone



数据库引用编号

19 个数据库交叉引用编号

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代谢反应

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23 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：

  • PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
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