Cerberin (BioDeep_00000013175)

   

PANOMIX_OTCML-2023 Volatile Flavor Compounds natural product


代谢物信息卡片


Cerberin; 2-Acetylneriifolin

化学式: C32H48O9 (576.3298158)
中文名称:
谱图信息: 最多检出来源 Chinese Herbal Medicine(otcml) 80%

分子结构信息

SMILES: CC1C(C(C(C(O1)OC2CCC3(C(C2)CCC4C3CCC5(C4(CCC5C6=CC(=O)OC6)O)C)C)OC(=O)C)OC)O
InChI: InChI=1S/C32H48O9/c1-17-26(35)27(37-5)28(40-18(2)33)29(39-17)41-21-8-11-30(3)20(15-21)6-7-24-23(30)9-12-31(4)22(10-13-32(24,31)36)19-14-25(34)38-16-19/h14,17,20-24,26-29,35-36H,6-13,15-16H2,1-5H3/t17-,20+,21-,22+,23-,24+,26-,27+,28-,29-,30-,31+,32-/m0/s1

描述信息

D020011 - Protective Agents > D002316 - Cardiotonic Agents > D002301 - Cardiac Glycosides
A cardenolide glycoside that is the 2-acetyl derivative of neriifolin.

同义名列表

4 个代谢物同义名

Cerberin; Cerberin; 2-Acetylneriifolin; 2-Acetylneriifolin; Cerberin



数据库引用编号

14 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(0)

BioCyc(0)

PlantCyc(0)

代谢反应

0 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

41 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：

  • PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。



文献列表

  • Md Shahadat Hossan, Zi-Yang Chan, Hilary M Collins, Fiona N Shipton, Mark S Butler, Mohammed Rahmatullah, Jong Bong Lee, Pavel Gershkovich, Leonid Kagan, Teng-Jin Khoo, Christophe Wiart, Tracey D Bradshaw. Cardiac glycoside cerberin exerts anticancer activity through PI3K/AKT/mTOR signal transduction inhibition. Cancer letters. 2019 07; 453(?):57-73. doi: 10.1016/j.canlet.2019.03.034. [PMID: 30930233]
  • Ritesh G Menezes, Muhammad Shariq Usman, Syed Ather Hussain, Mohammed Madadin, Tariq Jamal Siddiqi, Huda Fatima, Pradhum Ram, Syed Bilal Pasha, S Senthilkumaran, Tooba Qadir Fatima, Sushil Allen Luis. Cerbera odollam toxicity: A review. Journal of forensic and legal medicine. 2018 Aug; 58(?):113-116. doi: 10.1016/j.jflm.2018.05.007. [PMID: 29778924]
  • Jérémy Carlier, Jérôme Guitton, Fabien Bévalot, Laurent Fanton, Yvan Gaillard. The principal toxic glycosidic steroids in Cerbera manghas L. seeds: identification of cerberin, neriifolin, tanghinin and deacetyltanghinin by UHPLC-HRMS/MS, quantification by UHPLC-PDA-MS. Journal of chromatography. B, Analytical technologies in the biomedical and life sciences. 2014 Jul; 962(?):1-8. doi: 10.1016/j.jchromb.2014.05.014. [PMID: 24878878]
  • Richard G Powell. Plant seeds as sources of potential industrial chemicals, pharmaceuticals, and pest control agents. Journal of natural products. 2009 Mar; 72(3):516-23. doi: 10.1021/np8006217. [PMID: 19209890]
  • I Kippen, N Nakata, J R Klinenberg. Uptake of uric acid by separated renal tubules of the rabbit. I. Characteristics of transport. The Journal of pharmacology and experimental therapeutics. 1977 Apr; 201(1):218-25. doi: NULL. [PMID: 15103]
  • R M Kater, N Carulli, F L Iber. Differences in the rate of ethanol metabolism in recently drinking alcoholic and nondrinking subjects. The American journal of clinical nutrition. 1969 Dec; 22(12):1608-17. doi: 10.1093/ajcn/22.12.1608. [PMID: 5362487]