S-Allylcysteine (BioDeep_00000011381)
Secondary id: BioDeep_00000397403
human metabolite PANOMIX_OTCML-2023 blood metabolite
代谢物信息卡片
2-Amino-3-(prop-2-en-1-ylsulphanyl)propanoic acid
化学式: C6H11NO2S (161.0510466)
中文名称: DL-S-烯丙基半胱氨酸, S-烯丙基-L-半胱氨酸
谱图信息:
最多检出来源 Homo sapiens(blood) 1.85%
Reviewed
Last reviewed on 2024-09-14.
Cite this Page
S-Allylcysteine. BioDeep Database v3. PANOMIX ltd, a top metabolomics service provider from China.
https://query.biodeep.cn/s/s-allylcysteine (retrieved
2024-11-03) (BioDeep RN: BioDeep_00000011381). Licensed
under the Attribution-Noncommercial 4.0 International License (CC BY-NC 4.0).
分子结构信息
SMILES: C=CCSCC(C(=O)O)N
InChI: InChI=1S/C6H11NO2S/c1-2-3-10-4-5(7)6(8)9/h2,5H,1,3-4,7H2,(H,8,9)
描述信息
Occurs in garlic. Potential nutriceutical. S-Allylcysteine is found in garden onion, soft-necked garlic, and onion-family vegetables.
S-Allylcysteine is found in garden onion. S-Allylcysteine occurs in garlic. Potential nutriceutica
D000970 - Antineoplastic Agents
S-Allyl-L-cysteine, one of the organosulfur compounds found in AGE, possess various biological effects including neurotrophic activity, anti-cancer activity, anti-inflammatory activity.
S-Allyl-L-cysteine, one of the organosulfur compounds found in AGE, possess various biological effects including neurotrophic activity, anti-cancer activity, anti-inflammatory activity.
同义名列表
12 个代谢物同义名
2-Amino-3-(prop-2-en-1-ylsulphanyl)propanoic acid; 2-amino-3-(prop-2-en-1-ylsulfanyl)propanoic acid; 2-Amino-3-(prop-2-en-1-ylsulphanyl)propanoate; 2-Amino-3-(prop-2-en-1-ylsulfanyl)propanoate; S-2-propenyl-L-cysteine; S-Allyl-L -cysteine; S-ALLYL-D-CYSTEINE; S-Allyl-L-cysteine; S-Allyl cysteine; S-Allylcysteine; allyl cysteine; L-DEOXYALLIIN
数据库引用编号
18 个数据库交叉引用编号
- ChEBI: CHEBI:74077
- KEGG: C16759
- PubChem: 98280
- HMDB: HMDB0034323
- Metlin: METLIN71319
- ChEMBL: CHEMBL1592541
- Wikipedia: S-Allyl cysteine
- MetaCyc: CPD-9298
- KNApSAcK: C00037771
- foodb: FDB012675
- chemspider: 88744
- CAS: 21593-77-1
- PMhub: MS000025364
- PubChem: 96023283
- PDB-CCD: I3L
- NIKKAJI: J490.173H
- RefMet: S-Allylcysteine
- medchemexpress: HY-W013573
分类词条
相关代谢途径
Reactome(0)
BioCyc(0)
PlantCyc(0)
代谢反应
0 个相关的代谢反应过程信息。
Reactome(0)
BioCyc(0)
WikiPathways(0)
Plant Reactome(0)
INOH(0)
PlantCyc(0)
COVID-19 Disease Map(0)
PathBank(0)
PharmGKB(0)
2 个相关的物种来源信息
在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：
- PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
- NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
- Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
- Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。
点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。
文献列表
- Hajime Moteki, Masahiko Ogihara, Mitsutoshi Kimura. Cell proliferation effects of S-allyl-L-cysteine are associated with phosphorylation of janus kinase 2, insulin-like growth factor type-I receptor tyrosine kinase, and extracellular signal-regulated kinase 2 in primary cultures of adult rat hepatocytes.
European journal of pharmacology.
2022 Jul; 927(?):175067. doi:
10.1016/j.ejphar.2022.175067. [PMID: 35654135] - Pin-Hua Chen, Chun-Han Chang, Wei-Sheng Lin, Kalyanam Nagabhushanam, Chi-Tang Ho, Min-Hsiung Pan. S-Allylcysteine Ameliorates Aging Features via Regulating Mitochondrial Dynamics in Naturally Aged C57BL/6J Mice.
Molecular nutrition & food research.
2022 04; 66(7):e2101077. doi:
10.1002/mnfr.202101077. [PMID: 35092643] - Ramkumar Samynathan, Umadevi Subramanian, Baskar Venkidasamy, Mohammad Ali Shariati, Ill-Min Chung, Muthu Thiruvengadam. S-Allylcysteine (SAC) Exerts Renoprotective Effects via Regulation of TGF- β1/Smad3 Pathway Mediated Matrix Remodeling in Chronic Renal Failure.
Current pharmaceutical design.
2022; 28(8):661-670. doi:
10.2174/1381612828666220401114301. [PMID: 35366767] - Syed Mohammed Basheeruddin Asdaq, Obulesu Challa, Abdulhakeem S Alamri, Walaa F Alsanie, Majid Alhomrani, Abdulrahman Hadi Almutiri, Majed Sadun Alshammari. Cytoprotective Potential of Aged Garlic Extract (AGE) and Its Active Constituent, S-allyl-l-cysteine, in Presence of Carvedilol during Isoproterenol-Induced Myocardial Disturbance and Metabolic Derangements in Rats.
Molecules (Basel, Switzerland).
2021 May; 26(11):. doi:
10.3390/molecules26113203. [PMID: 34071846] - Md Masud Rana, Kota Shiozawa, Katsuyuki Mukai, Katsuhiko Takayanagi, Koichi Eguchi, Halima Sultana, Yusuke Ohsaki, Michio Komai, Hitoshi Shirakawa. S-allyl Cysteine Enhances Testosterone Production in Mice and Mouse Testis-Derived I-10 Cells.
Molecules (Basel, Switzerland).
2021 Mar; 26(6):. doi:
10.3390/molecules26061697. [PMID: 33803601] - Kazuki Kurihara, Hajime Moteki, Hideshi Natsume, Masahiko Ogihara, Mitsutoshi Kimura. The Enhancing Effects of S-Allylcysteine on Liver Regeneration Are Associated with Increased Expression of mRNAs Encoding IGF-1 and Its Receptor in Two-Thirds Partially Hepatectomized Rats.
Biological & pharmaceutical bulletin.
2020; 43(11):1776-1784. doi:
10.1248/bpb.b20-00495. [PMID: 33132323] - A-Sung Lee, Sang-Hee Lee, Seunghyung Lee, Boo-Keun Yang. Effects of streptozotocin and S-allyl-L-cysteine on motility, plasma membrane integrity, and mitochondrial activity of boar spermatozoa.
Tropical animal health and production.
2020 Jan; 52(1):437-444. doi:
10.1007/s11250-019-01983-2. [PMID: 31301041] - V V Sathibabu Uddandrao, Parim Brahmanaidu, Ramavat Ravindarnaik, Pothani Suresh, S Vadivukkarasi, Ganapathy Saravanan. Restorative potentiality of S-allylcysteine against diabetic nephropathy through attenuation of oxidative stress and inflammation in streptozotocin-nicotinamide-induced diabetic rats.
European journal of nutrition.
2019 Sep; 58(6):2425-2437. doi:
10.1007/s00394-018-1795-x. [PMID: 30062492] - Mohammad-Reza Khajevand-Khazaei, Shekoofe Azimi, Ladan Sedighnejad, Sepide Salari, Atefeh Ghorbanpour, Tourandokht Baluchnejadmojarad, Parvaneh Mohseni-Moghaddam, Safoura Khamse, Mehrdad Roghani. S-allyl cysteine protects against lipopolysaccharide-induced acute kidney injury in the C57BL/6 mouse strain: Involvement of oxidative stress and inflammation.
International immunopharmacology.
2019 Apr; 69(?):19-26. doi:
10.1016/j.intimp.2019.01.026. [PMID: 30665040] - Preethi Johnson, Chitra Loganathan, Ancy Iruthayaraj, Kumaradhas Poomani, Palvannan Thayumanavan. S-allyl cysteine as potent anti-gout drug: Insight into the xanthine oxidase inhibition and anti-inflammatory activity.
Biochimie.
2018 Nov; 154(?):1-9. doi:
10.1016/j.biochi.2018.07.015. [PMID: 30059711] - Taehoon Park, Ju-Hee Oh, Joo Hyun Lee, Sang Cheol Park, Young Pyo Jang, Young-Joo Lee. Oral Administration of (S)-Allyl-l-Cysteine and Aged Garlic Extract to Rats: Determination of Metabolites and Their Pharmacokinetics.
Planta medica.
2017 Nov; 83(17):1351-1360. doi:
10.1055/s-0043-111895. [PMID: 28561204] - Parim Brahmanaidu, V V Sathibabu Uddandrao, Vadivukkarasi Sasikumar, Ramavat Ravindar Naik, Suresh Pothani, Mustapha Sabana Begum, M Prasanna Rajeshkumar, Chandrasekar Varatharaju, Balaji Meriga, P Rameshreddy, A Kalaivani, Ganapathy Saravanan. Reversal of endothelial dysfunction in aorta of streptozotocin-nicotinamide-induced type-2 diabetic rats by S-Allylcysteine.
Molecular and cellular biochemistry.
2017 Aug; 432(1-2):25-32. doi:
10.1007/s11010-017-2994-0. [PMID: 28258439] - Yue-E Sun, Wei-Dong Wang. Study on the interaction of bioactive compound S-allyl cysteine from garlic with serum albumin.
Journal of food and drug analysis.
2017 04; 25(2):385-390. doi:
10.1016/j.jfda.2016.08.013. [PMID: 28911681] - Toshiaki Matsutomo, Mitsuyasu Ushijima, Yukihiro Kodera, Masashi Nakamoto, Miyuki Takashima, Naoaki Morihara, Koichi Tamura. Metabolomic study on the antihypertensive effect of S-1-propenylcysteine in spontaneously hypertensive rats using liquid chromatography coupled with quadrupole-Orbitrap mass spectrometry.
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences.
2017 Mar; 1046(?):147-155. doi:
10.1016/j.jchromb.2017.01.029. [PMID: 28183044] - Tourandokht Baluchnejadmojarad, Zahra Kiasalari, Siamak Afshin-Majd, Zahra Ghasemi, Mehrdad Roghani. S-allyl cysteine ameliorates cognitive deficits in streptozotocin-diabetic rats via suppression of oxidative stress, inflammation, and acetylcholinesterase.
European journal of pharmacology.
2017 Jan; 794(?):69-76. doi:
10.1016/j.ejphar.2016.11.033. [PMID: 27887948] - Isabel Denzer, Gerald Münch, Monika Pischetsrieder, Kristina Friedland. S-allyl-L-cysteine and isoliquiritigenin improve mitochondrial function in cellular models of oxidative and nitrosative stress.
Food chemistry.
2016 Mar; 194(?):843-8. doi:
10.1016/j.foodchem.2015.08.052. [PMID: 26471626] - Hirotaka Amano, Daichi Kazamori, Kenji Itoh. Pharmacokinetics of S-Allyl-l-cysteine in Rats Is Characterized by High Oral Absorption and Extensive Renal Reabsorption.
The Journal of nutrition.
2016 Feb; 146(2):456S-459S. doi:
10.3945/jn.114.201749. [PMID: 26764325] - Hirotaka Amano, Daichi Kazamori, Kenji Itoh, Yukihiro Kodera. Metabolism, excretion, and pharmacokinetics of S-allyl-L-cysteine in rats and dogs.
Drug metabolism and disposition: the biological fate of chemicals.
2015 May; 43(5):749-55. doi:
10.1124/dmd.115.063230. [PMID: 25681129] - Dehong Tan, Yao Zhang, Lulu Chen, Ling Liu, Xuan Zhang, Zhaoxia Wu, Bing Bai, Shujuan Ji. Decreased glycation and structural protection properties of γ-glutamyl-S-allyl-cysteine peptide isolated from fresh garlic scales (Allium sativum L.).
Natural product research.
2015; 29(23):2219-22. doi:
10.1080/14786419.2014.1003065. [PMID: 25631559] - Sanghee Lee, Nae In Chang, Miyoung Yoo, Jung Hoon Choi, Dongbin Shin. Development and validation of S-allyl-L-cysteine in rat plasma using a mixed-mode reversed-phase and cation-exchange LC-ESI-MS/MS method: application to pharmacokinetic studies.
Journal of chromatographic science.
2015 Jan; 53(1):54-9. doi:
10.1093/chromsci/bmu013. [PMID: 24668040] - B K Nirala, N K Gohil. Effect of garlic component s-allyl cysteine sulfoxide on glycated human serum albumin induced activation of endothelial cells: an in vitro study.
European review for medical and pharmacological sciences.
2015; 19(11):2125-31. doi:
NULL. [PMID: 26125278] - Tania Gómez-Sierra, Eduardo Molina-Jijón, Edilia Tapia, Rogelio Hernández-Pando, Wylly Ramsés García-Niño, Perla D Maldonado, José Luis Reyes, Diana Barrera-Oviedo, Ismael Torres, José Pedraza-Chaverri. S-allylcysteine prevents cisplatin-induced nephrotoxicity and oxidative stress.
The Journal of pharmacy and pharmacology.
2014 Sep; 66(9):1271-81. doi:
10.1111/jphp.12263. [PMID: 24779924] - Pulla Reddy Avula, Syed Mohammed Asdaq, Mohammed Asad. Effect of aged garlic extract and s-allyl cysteine and their interaction with atenolol during isoproterenol induced myocardial toxicity in rats.
Indian journal of pharmacology.
2014 Jan; 46(1):94-9. doi:
10.4103/0253-7613.125185. [PMID: 24550592] - Ganapathy Saravanan, Ponnusamy Ponmurugan, Mustapha Shabana Begum. Effect of S-allylcysteine, a sulphur containing amino acid on iron metabolism in streptozotocin induced diabetic rats.
Journal of trace elements in medicine and biology : organ of the Society for Minerals and Trace Elements (GMS).
2013 Apr; 27(2):143-7. doi:
10.1016/j.jtemb.2012.07.009. [PMID: 22981633] - Man-Hui Pai, Yueh-Hsiung Kuo, En-Pei Isabel Chiang, Feng-Yao Tang. S-Allylcysteine inhibits tumour progression and the epithelial-mesenchymal transition in a mouse xenograft model of oral cancer.
The British journal of nutrition.
2012 Jul; 108(1):28-38. doi:
10.1017/s0007114511005307. [PMID: 22011514] - Ganapathy Saravanan, Ponnusamy Ponmurugan. Antidiabetic effect of S-allylcysteine: effect on thyroid hormone and circulatory antioxidant system in experimental diabetic rats.
Journal of diabetes and its complications.
2012 Jul; 26(4):280-5. doi:
10.1016/j.jdiacomp.2012.03.024. [PMID: 22541895] - Chan Wok Sohn, Hyunae Kim, Bo Ram You, Min Jee Kim, Hyo Jin Kim, Ji Yeon Lee, Dai-Eun Sok, Jin Hee Kim, Kun Jong Lee, Mee Ree Kim. High temperature- and high pressure-processed garlic improves lipid profiles in rats fed high cholesterol diets.
Journal of medicinal food.
2012 May; 15(5):435-40. doi:
10.1089/jmf.2011.1922. [PMID: 22404600] - Mei-chin Mong, Mei-chin Yin. Nuclear factor κB-dependent anti-inflammatory effects of s-allyl cysteine and s-propyl cysteine in kidney of diabetic mice.
Journal of agricultural and food chemistry.
2012 Mar; 60(12):3158-65. doi:
10.1021/jf3002685. [PMID: 22394022] - Samir Mandal, Sudip Mukherjee, Kaustav Dutta Chowdhury, Avik Sarkar, Kankana Basu, Soumosish Paul, Debasish Karmakar, Mahasweta Chatterjee, Tuli Biswas, Gobinda Chandra Sadhukhan, Gargi Sen. S-allyl cysteine in combination with clotrimazole downregulates Fas induced apoptotic events in erythrocytes of mice exposed to lead.
Biochimica et biophysica acta.
2012 Jan; 1820(1):9-23. doi:
10.1016/j.bbagen.2011.09.019. [PMID: 22033380] - Ganapathy Saravanan, Ponnusamy Ponmurugan. Ameliorative potential of S-allyl cysteine on oxidative stress in STZ induced diabetic rats.
Chemico-biological interactions.
2011 Jan; 189(1-2):100-6. doi:
10.1016/j.cbi.2010.10.001. [PMID: 20951120] - Ganapathy Saravanan, Ponnusamy Ponmurugan. Beneficial effect of S-allylcysteine (SAC) on blood glucose and pancreatic antioxidant system in streptozotocin diabetic rats.
Plant foods for human nutrition (Dordrecht, Netherlands).
2010 Dec; 65(4):374-8. doi:
10.1007/s11130-010-0192-2. [PMID: 20839055] - G Saravanan, P Ponmurugan, G P Senthil Kumar, T Rajarajan. Antidiabetic effect of S-allylcysteine: Effect on plasma and tissue glycoproteins in experimental diabetes.
Phytomedicine : international journal of phytotherapy and phytopharmacology.
2010 Dec; 17(14):1086-9. doi:
10.1016/j.phymed.2010.04.008. [PMID: 20576413] - S M Asdaq, M N Inamdar. Potential of garlic and its active constituent, S-allyl cysteine, as antihypertensive and cardioprotective in presence of captopril.
Phytomedicine : international journal of phytotherapy and phytopharmacology.
2010 Nov; 17(13):1016-26. doi:
10.1016/j.phymed.2010.07.012. [PMID: 20739164] - Hiroji Shinkawa, Shigekazu Takemura, Yukiko Minamiyama, Shintaro Kodai, Takuma Tsukioka, Mayuko Osada-Oka, Shoji Kubo, Shigeru Okada, Shigefumi Suehiro. S-allylcysteine is effective as a chemopreventive agent against porcine serum-induced hepatic fibrosis in rats.
Osaka city medical journal.
2009 Dec; 55(2):61-9. doi:
NULL. [PMID: 20088405] - Vinayagam Magendiramani, Syed Umesalma, Srinivasan Kalayarasan, Ponnuraj Nagendraprabhu, Jagadeesan Arunkumar, Ganapasam Sudhandiran. S-allylcysteine attenuates renal injury by altering the expressions of iNOS and matrix metallo proteinase-2 during cyclosporine-induced nephrotoxicity in Wistar rats.
Journal of applied toxicology : JAT.
2009 Aug; 29(6):522-30. doi:
10.1002/jat.1437. [PMID: 19391111] - Rachel M Novick, Adnan A Elfarra. Purification and characterization of flavin-containing monooxygenase isoform 3 from rat kidney microsomes.
Drug metabolism and disposition: the biological fate of chemicals.
2008 Dec; 36(12):2468-74. doi:
10.1124/dmd.108.021436. [PMID: 18775983] - Mannangatti Padmanabhan, Murugan Rajadurai, Ponnian Stanely Mainzen Prince. Preventive effect of S-allylcysteine on membrane-bound enzymes and glycoproteins in normal and isoproterenol-induced cardiac toxicity in male Wistar rats.
Basic & clinical pharmacology & toxicology.
2008 Dec; 103(6):507-13. doi:
10.1111/j.1742-7843.2008.00244.x. [PMID: 19067678] - Chun-che Lin, Mei-chin Yin, Wen-hu Liu. Alleviative effects of s-allyl cysteine and s-ethyl cysteine on MCD diet-induced hepatotoxicity in mice.
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association.
2008 Nov; 46(11):3401-6. doi:
10.1016/j.fct.2008.08.010. [PMID: 18786595] - Sabina Segoviano-Murillo, Dolores Javier Sánchez-González, Claudia María Martínez-Martínez, Cristino Cruz, Perla D Maldonado, José Pedraza-Chaverrí. S-allylcysteine ameliorates ischemia and reperfusion induced renal damage.
Phytotherapy research : PTR.
2008 Jun; 22(6):836-40. doi:
10.1002/ptr.2396. [PMID: 18381751] - Shin Chet Chuah, Philip K Moore, Yi Zhun Zhu. S-allylcysteine mediates cardioprotection in an acute myocardial infarction rat model via a hydrogen sulfide-mediated pathway.
American journal of physiology. Heart and circulatory physiology.
2007 Nov; 293(5):H2693-701. doi:
10.1152/ajpheart.00853.2007. [PMID: 17766469] - Göksel Sener, Abdullah Sakarcan, Berrak C Yegen. Role of garlic in the prevention of ischemia-reperfusion injury.
Molecular nutrition & food research.
2007 Nov; 51(11):1345-52. doi:
10.1002/mnfr.200700078. [PMID: 17966137] - Cristino Cruz, Ricardo Correa-Rotter, Dolores Javier Sánchez-González, Rogelio Hernández-Pando, Perla D Maldonado, Claudia María Martínez-Martínez, Omar Noel Medina-Campos, Edilia Tapia, Diana Aguilar, Yolanda I Chirino, José Pedraza-Chaverri. Renoprotective and antihypertensive effects of S-allylcysteine in 5/6 nephrectomized rats.
American journal of physiology. Renal physiology.
2007 Nov; 293(5):F1691-8. doi:
10.1152/ajprenal.00235.2007. [PMID: 17686953] - Qingjun Chu, Davy T W Lee, Sai Wah Tsao, Xianghong Wang, Yong Chuan Wong. S-allylcysteine, a water-soluble garlic derivative, suppresses the growth of a human androgen-independent prostate cancer xenograft, CWR22R, under in vivo conditions.
BJU international.
2007 Apr; 99(4):925-32. doi:
10.1111/j.1464-410x.2006.06639.x. [PMID: 17155983] - Shintaro Kodai, Shigekazu Takemura, Yukiko Minamiyama, Seikan Hai, Satoshi Yamamoto, Shoji Kubo, Yasukazu Yoshida, Etsuo Niki, Shigeru Okada, Kazuhiro Hirohashi, Shigefumi Suehiro. S-allyl cysteine prevents CCl(4)-induced acute liver injury in rats.
Free radical research.
2007 Apr; 41(4):489-97. doi:
10.1080/10715760601118361. [PMID: 17454131] - M Padmanabhan, P Stanely Mainzen Prince. S-allylcysteine ameliorates isoproterenol-induced cardiac toxicity in rats by stabilizing cardiac mitochondrial and lysosomal enzymes.
Life sciences.
2007 Feb; 80(10):972-8. doi:
10.1016/j.lfs.2006.11.028. [PMID: 17182065] - Cheng-Chin Hsu, Chun-Che Lin, Ting-Sin Liao, Mei-Chin Yin. Protective effect of s-allyl cysteine and s-propyl cysteine on acetaminophen-induced hepatotoxicity in mice.
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association.
2006 Mar; 44(3):393-7. doi:
10.1016/j.fct.2005.08.012. [PMID: 16181716] - Shinjiro Mizuguchi, Shigekazu Takemura, Yukiko Minamiyama, Shintaro Kodai, Takuma Tsukioka, Kiyotoshi Inoue, Shigeru Okada, Shigefumi Suehiro. S-allyl cysteine attenuated CCl4-induced oxidative stress and pulmonary fibrosis in rats.
BioFactors (Oxford, England).
2006; 26(1):81-92. doi:
10.1002/biof.5520260108. [PMID: 16614485] - Marco A Velasco-Velázquez, Perla D Maldonado, Diana Barrera, Víctor Torres, Alejandro Zentella-Dehesa, José Pedraza-Chaverrí. Aged garlic extract induces proliferation and ameliorates gentamicin-induced toxicity in LLC-PK1 cells.
Phytotherapy research : PTR.
2006 Jan; 20(1):76-8. doi:
10.1002/ptr.1780. [PMID: 16397848] - Michel Demeule, Mathieu Brossard, Sandra Turcotte, Anthony Regina, Julie Jodoin, Richard Béliveau. Diallyl disulfide, a chemopreventive agent in garlic, induces multidrug resistance-associated protein 2 expression.
Biochemical and biophysical research communications.
2004 Nov; 324(2):937-45. doi:
10.1016/j.bbrc.2004.09.141. [PMID: 15474518] - Chun-che Lin, Mei-chin Yin, Cheng-chin Hsu, Meng-pei Lin. Effect of five cysteine-containing compounds on three lipogenic enzymes in Balb/cA mice consuming a high saturated fat diet.
Lipids.
2004 Sep; 39(9):843-8. doi:
10.1007/s11745-004-1305-4. [PMID: 15669759] - Cheng-chin Hsu, Chien-ning Huang, Yu-chuan Hung, Mei-chin Yin. Five cysteine-containing compounds have antioxidative activity in Balb/cA mice.
The Journal of nutrition.
2004 Jan; 134(1):149-52. doi:
10.1093/jn/134.1.149. [PMID: 14704308] - Perla D Maldonado, Diana Barrera, Isabel Rivero, Rachel Mata, Omar N Medina-Campos, Rogelio Hernández-Pando, José Pedraza-Chaverrí. Antioxidant S-allylcysteine prevents gentamicin-induced oxidative stress and renal damage.
Free radical biology & medicine.
2003 Aug; 35(3):317-24. doi:
10.1016/s0891-5849(03)00312-5. [PMID: 12885594] - Renee J Krause, Steven C Glocke, Adnan A Elfarra. Sulfoxides as urinary metabolites of S-allyl-L-cysteine in rats: evidence for the involvement of flavin-containing monooxygenases.
Drug metabolism and disposition: the biological fate of chemicals.
2002 Oct; 30(10):1137-42. doi:
10.1124/dmd.30.10.1137. [PMID: 12228191] - Qiaoling Peng, Amber R Buz'Zard, Benjamin H S Lau. Neuroprotective effect of garlic compounds in amyloid-beta peptide-induced apoptosis in vitro.
Medical science monitor : international medical journal of experimental and clinical research.
2002 Aug; 8(8):BR328-37. doi:
NULL. [PMID: 12165737] - R T Rosen, R D Hiserodt, E K Fukuda, R J Ruiz, Z Zhou, J Lech, S L Rosen, T G Hartman. Determination of allicin, S-allylcysteine and volatile metabolites of garlic in breath, plasma or simulated gastric fluids.
The Journal of nutrition.
2001 03; 131(3s):968S-71S. doi:
10.1093/jn/131.3.968s. [PMID: 11238798] - S T Ohnishi, T Ohnishi. In vitro effects of aged garlic extract and other nutritional supplements on sickle erythrocytes.
The Journal of nutrition.
2001 Mar; 131(3s):1085S-92S. doi:
10.1093/jn/131.3.1085s. [PMID: 11238822] - Y Y Yeh, L Liu. Cholesterol-lowering effect of garlic extracts and organosulfur compounds: human and animal studies.
The Journal of nutrition.
2001 03; 131(3s):989S-93S. doi:
10.1093/jn/131.3.989s. [PMID: 11238803] - M G Mostafa, T Mima, S T Ohnishi, K Mori. S-allylcysteine ameliorates doxorubicin toxicity in the heart and liver in mice.
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