Cynaropicrin

2-PROPENOIC ACID, 2-(HYDROXYMETHYL)-, DODECAHYDRO-8-HYDROXY-3,6,9-TRIS(METHYLENE)-2-OXOAZULENO(4,5-B)FURAN-4-YL ESTER, (3AR-(3A.ALPHA.,4.ALPHA.,6A.ALPHA.,8.BETA.,9A.ALPHA.,9B.BETA.))-

C19H22O6 (346.1416312)


Constituent of Cynara scolymus (artichoke). Cynaropicrin is found in cardoon, globe artichoke, and root vegetables. Cynaropicrin is found in cardoon. Cynaropicrin is a constituent of Cynara scolymus (artichoke). Cynaropicrin is a sesquiterpene lactone. Cynaropicrin is a natural product found in Pleiotaxis rugosa, Pseudostifftia kingii, and other organisms with data available. See also: Cynara scolymus leaf (part of). D009676 - Noxae > D003603 - Cytotoxins Cynaropicrin is a sesquiterpene lactone which can inhibit tumor necrosis factor (TNF-α) release with IC50s of 8.24 and 3.18 μM for murine and human macrophage cells, respectively. Cynaropicrin also inhibits the increase of cartilage degradation factor (MMP13) and suppresses NF-κB signaling. Cynaropicrin is a sesquiterpene lactone which can inhibit tumor necrosis factor (TNF-α) release with IC50s of 8.24 and 3.18 μM for murine and human macrophage cells, respectively. Cynaropicrin also inhibits the increase of cartilage degradation factor (MMP13) and suppresses NF-κB signaling.

   

Santonin

InChI=1/C15H18O3/c1-8-10-4-6-15(3)7-5-11(16)9(2)12(15)13(10)18-14(8)17/h5,7-8,10,13H,4,6H2,1-3H3/t8-,10-,13-,15-/m0/s

C15H18O3 (246.1255878)


Alpha-santonin is a santonin that is 3a,5,5a,9b-tetrahydronaphtho[1,2-b]furan-2,8(3H,4H)-dione substituted by methyl groups at positions 3, 5a and 9. It has a role as a plant metabolite. It is a botanical anti-fungal agent and a santonin. Santonin is a natural product found in Artemisia spicigera, Artemisia diffusa, and other organisms with data available. Anthelmintic isolated from the dried unexpanded flower heads of Artemisia maritima and other species of Artemisia found principally in Russian and Chinese Turkestan and the Southern Ural region. (From Merck, 11th ed.) See also: ... View More ... A santonin that is 3a,5,5a,9b-tetrahydronaphtho[1,2-b]furan-2,8(3H,4H)-dione substituted by methyl groups at positions 3, 5a and 9. D000890 - Anti-Infective Agents > D000977 - Antiparasitic Agents > D000871 - Anthelmintics C254 - Anti-Infective Agent > C276 - Antiparasitic Agent > C250 - Antihelminthic Agent ADP-ribose 1"-2" cyclic phosphate is a cyclic phosphate nucleotide that arises from tRNA processing. In eukaryotic cells, pre-tRNAs spliced by a pathway that produces a 3,5-phosphodiester, 2-phosphomonoester linkage contain a 2-phosphate group adjacent to the tRNA anticodon. This 2-phosphate is transferred to NAD to give adenosine diphosphate (ADP)-ribose 1", 2"-cyclic phosphate (Appr>p), which is subsequently metabolized to ADP-ribose 1-phosphate (Appr-1p). The latter reaction is catalyzed by a cyclic phosphodiesterase (CPDase). (PMID: 9148938). One molecule of ADP-ribose 1",2"-cyclic phosphate (Appr>p) is formed during each of the approximately 500 000 tRNA splicing events. [HMDB] Constituent of Physalis peruviana (Cape gooseberry). Withaperuvin F is found in fruits. Alkaloid found on the leaf surfaces of Brassica oleracea cv. botrytis (cauliflower) [DFC]. Cabbage identification factor 1 is found in brassicas. CONFIDENCE Reference Standard (Level 1); INTERNAL_ID 2267 INTERNAL_ID 2267; CONFIDENCE Reference Standard (Level 1) relative retention time with respect to 9-anthracene Carboxylic Acid is 0.918 relative retention time with respect to 9-anthracene Carboxylic Acid is 0.917 relative retention time with respect to 9-anthracene Carboxylic Acid is 0.915 [Raw Data] CB081_Santonin_pos_30eV_CB000033.txt [Raw Data] CB081_Santonin_pos_10eV_CB000033.txt [Raw Data] CB081_Santonin_pos_40eV_CB000033.txt [Raw Data] CB081_Santonin_pos_20eV_CB000033.txt [Raw Data] CB081_Santonin_pos_50eV_CB000033.txt Santonin is an active principle of the plant Artemisia cina, which is formely used to treat worms[1]. Santonin is an active principle of the plant Artemisia cina, which is formely used to treat worms[1].

   

(+)-Sesamin

1,3-BENZODIOXOLE, 5,5-(TETRAHYDRO-1H,3H-FURO(3,4-C)FURAN-1,4-DIYL)BIS-, (1S-(1.ALPHA.,3A .ALPHA.,4.ALPHA.,6A .ALPHA.))-

C20H18O6 (354.1103328)


(+)-Sesamin, also known as fagarol or sezamin, belongs to the class of organic compounds known as furanoid lignans. These are lignans with a structure that contains either a tetrahydrofuran ring, a furan ring, or a furofuan ring system, that arises from the joining of the two phenylpropanoid units. (+)-Sesamin is an extremely weak basic (essentially neutral) compound (based on its pKa). (+)-Sesamin is found, on average, in the highest concentration within sesames. (+)-Sesamin has also been detected, but not quantified in, several different foods, such as fats and oils, flaxseeds, ginkgo nuts, and ucuhuba. This could make (+)-sesamin a potential biomarker for the consumption of these foods. (+)-sesamin is a lignan that consists of tetrahydro-1H,3H-furo[3,4-c]furan substituted by 1,3-benzodioxole groups at positions 1 and 4 (the 1S,3aR,4S,6aR stereoisomer). Isolated from Cinnamomum camphora, it exhibits cytotoxic activity. It has a role as an antineoplastic agent, a neuroprotective agent and a plant metabolite. It is a lignan, a member of benzodioxoles and a furofuran. Sesamin is a natural product found in Pandanus boninensis, Podolepis rugata, and other organisms with data available. See also: Sesame Oil (part of). A lignan that consists of tetrahydro-1H,3H-furo[3,4-c]furan substituted by 1,3-benzodioxole groups at positions 1 and 4 (the 1S,3aR,4S,6aR stereoisomer). Isolated from Cinnamomum camphora, it exhibits cytotoxic activity. Constituent of sesame oil. (+)-Sesamin is found in many foods, some of which are ginkgo nuts, sesame, flaxseed, and fats and oils. D057847 - Lipid Regulating Agents > D000960 - Hypolipidemic Agents > D000924 - Anticholesteremic Agents D002317 - Cardiovascular Agents > D000959 - Antihypertensive Agents D020011 - Protective Agents > D000975 - Antioxidants D009676 - Noxae > D000963 - Antimetabolites (-)-Asarinin is a extract lignan from Asarum sieboldii Miq., mainly produced in roots of this herb[1]. (-)-Asarinin is a extract lignan from Asarum sieboldii Miq., mainly produced in roots of this herb[1]. (-)-Asarinin is a extract lignan from Asarum sieboldii Miq., mainly produced in roots of this herb[1]. (-)-Asarinin is a extract lignan from Asarum sieboldii Miq., mainly produced in roots of this herb[1]. Sesamin, abundant lignan found in sesame oil, is a potent and selective delta 5 desaturase inhibitor in polyunsaturated fatty acid biosynthesis. Sesamin exerts effective neuroprotection against cerbral ischemia[1][2]. Sesamin, abundant lignan found in sesame oil, is a potent and selective delta 5 desaturase inhibitor in polyunsaturated fatty acid biosynthesis. Sesamin exerts effective neuroprotection against cerbral ischemia[1][2].

   

Anacyclin

Anacyclin; (2E,4E)-N-(2-Methylpropyl)-2,4-tetradecadiene-8,10-diynamide

C18H25NO (271.193604)


   

Methyl (Z)-2-decene-4,6,8-triynoate

Dehydromatricaria methyl ester, 1-(14)C-labeled

C11H8O2 (172.0524268)


Methyl (Z)-2-decene-4,6,8-triynoate occurs in Artemisia vulgaris (mugwort). Occurs in Artemisia vulgaris (mugwort)

   

(Z)-2-Decene-4,6,8-triynoic acid methylester

2-Decene-4,6,8-triynoic acid, methyl ester, (Z)-

C11H8O2 (172.0524268)


   

Loliolide

(6S,7aR)-6-hydroxy-4,4,7a-trimethyl-2,4,5,6,7,7a-hexahydro-1-benzofuran-2-one

C11H16O3 (196.1099386)


Loliolide, also known as (3s5r)-loliolide, is a member of the class of compounds known as benzofurans. Benzofurans are organic compounds containing a benzene ring fused to a furan. Furan is a five-membered aromatic ring with four carbon atoms and one oxygen atom. Loliolide is soluble (in water) and an extremely weak acidic compound (based on its pKa). Loliolide can be found in sunflower, tea, and wakame, which makes loliolide a potential biomarker for the consumption of these food products.

   

Dodecadienoic acid

dodeca-2,4-dienoic acid

C12H20O2 (196.14632200000003)


Dodecadienoic acid, also known as dodecadienoate, is a member of the class of compounds known as medium-chain fatty acids. Medium-chain fatty acids are fatty acids with an aliphatic tail that contains between 4 and 12 carbon atoms. Dodecadienoic acid is practically insoluble (in water) and a weakly acidic compound (based on its pKa). Dodecadienoic acid can be found in common buckwheat and dandelion, which makes dodecadienoic acid a potential biomarker for the consumption of these food products.

   

sesamin

1,3-Benzodioxole, 5,5-(tetrahydro-1H,3H-furo(3,4-c)furan-1,4-diyl)bis-, (1S-(1.alpha.,3a.alpha.,4.alpha.,6a.alpha.))-

C20H18O6 (354.1103328)


D057847 - Lipid Regulating Agents > D000960 - Hypolipidemic Agents > D000924 - Anticholesteremic Agents D002317 - Cardiovascular Agents > D000959 - Antihypertensive Agents D020011 - Protective Agents > D000975 - Antioxidants D009676 - Noxae > D000963 - Antimetabolites relative retention time with respect to 9-anthracene Carboxylic Acid is 1.233 relative retention time with respect to 9-anthracene Carboxylic Acid is 1.236 Asarinin is a natural product found in Piper mullesua, Machilus thunbergii, and other organisms with data available. (-)-Asarinin is a natural product found in Zanthoxylum austrosinense, Horsfieldia irya, and other organisms with data available. (-)-Asarinin is a extract lignan from Asarum sieboldii Miq., mainly produced in roots of this herb[1]. (-)-Asarinin is a extract lignan from Asarum sieboldii Miq., mainly produced in roots of this herb[1]. (-)-Asarinin is a extract lignan from Asarum sieboldii Miq., mainly produced in roots of this herb[1]. (-)-Asarinin is a extract lignan from Asarum sieboldii Miq., mainly produced in roots of this herb[1]. Sesamin, abundant lignan found in sesame oil, is a potent and selective delta 5 desaturase inhibitor in polyunsaturated fatty acid biosynthesis. Sesamin exerts effective neuroprotection against cerbral ischemia[1][2]. Sesamin, abundant lignan found in sesame oil, is a potent and selective delta 5 desaturase inhibitor in polyunsaturated fatty acid biosynthesis. Sesamin exerts effective neuroprotection against cerbral ischemia[1][2].

   

Cynaropicrin

2-PROPENOIC ACID, 2-(HYDROXYMETHYL)-, DODECAHYDRO-8-HYDROXY-3,6,9-TRIS(METHYLENE)-2-OXOAZULENO(4,5-B)FURAN-4-YL ESTER, (3AR-(3A.ALPHA.,4.ALPHA.,6A.ALPHA.,8.BETA.,9A.ALPHA.,9B.BETA.))-

C19H22O6 (346.1416312)


Cynaropicrin is a sesquiterpene lactone. Cynaropicrin is a natural product found in Pleiotaxis rugosa, Pseudostifftia kingii, and other organisms with data available. See also: Cynara scolymus leaf (part of). D009676 - Noxae > D003603 - Cytotoxins Cynaropicrin is a sesquiterpene lactone which can inhibit tumor necrosis factor (TNF-α) release with IC50s of 8.24 and 3.18 μM for murine and human macrophage cells, respectively. Cynaropicrin also inhibits the increase of cartilage degradation factor (MMP13) and suppresses NF-κB signaling. Cynaropicrin is a sesquiterpene lactone which can inhibit tumor necrosis factor (TNF-α) release with IC50s of 8.24 and 3.18 μM for murine and human macrophage cells, respectively. Cynaropicrin also inhibits the increase of cartilage degradation factor (MMP13) and suppresses NF-κB signaling.

   

loliolide

2(4H)-Benzofuranone, 5,6,7,7a-tetrahydro-6-hydroxy-4,4,7a-trimethyl-, (6S-cis)-

C11H16O3 (196.1099386)


A natural product found in Brachystemma calycinum.

   

SFE 11:7

methyl (2E)-dec-2-en-4,6,8-triynoate

C11H8O2 (172.0524268)


   

cis-DME

methyl dec-2Z-en-4,6,8-triynoate

C11H8O2 (172.0524268)


   

(2E,4E)-dodeca-2,4-dienoic acid

(2E,4E)-dodeca-2,4-dienoic acid

C12H20O2 (196.14632200000003)


   

Dehydromatricaria ester

Dehydromatricaria ester

C11H8O2 (172.0524268)


   

tetradec-6-en-8,10,12-triyn-3-one

tetradec-6-en-8,10,12-triyn-3-one

C14H14O (198.1044594)


   

(3e,5e)-trideca-3,5-dien-7,9,11-triyn-1-ol

(3e,5e)-trideca-3,5-dien-7,9,11-triyn-1-ol

C13H12O (184.08881019999998)


   

n-(2-methylpropyl)dec-2-en-4,6,8-triynimidic acid

n-(2-methylpropyl)dec-2-en-4,6,8-triynimidic acid

C14H15NO (213.115358)


   

(2e,8e)-n-methyl-n-(2-methylpropyl)deca-2,8-dien-4,6-diynamide

(2e,8e)-n-methyl-n-(2-methylpropyl)deca-2,8-dien-4,6-diynamide

C15H19NO (229.14665639999998)


   

(2e)-n-(2-methylpropyl)dec-2-en-4,6,8-triynimidic acid

(2e)-n-(2-methylpropyl)dec-2-en-4,6,8-triynimidic acid

C14H15NO (213.115358)


   

n-methyl-n-(2-methylpropyl)deca-2,8-dien-4,6-diynamide

n-methyl-n-(2-methylpropyl)deca-2,8-dien-4,6-diynamide

C15H19NO (229.14665639999998)


   

(2e,4e)-n-(2-methylpropyl)tetradeca-2,4-dienimidic acid

(2e,4e)-n-(2-methylpropyl)tetradeca-2,4-dienimidic acid

C18H33NO (279.2562008)


   

(2e,4e)-n-(2-methylpropyl)tetradeca-2,4-dien-8,10-diynimidic acid

(2e,4e)-n-(2-methylpropyl)tetradeca-2,4-dien-8,10-diynimidic acid

C18H25NO (271.193604)


   

(2e,4e,12e)-n-(2-methylpropyl)tetradeca-2,4,12-trien-8,10-diynimidic acid

(2e,4e,12e)-n-(2-methylpropyl)tetradeca-2,4,12-trien-8,10-diynimidic acid

C18H23NO (269.1779548)


   

n-methyl-n-(2-methylpropyl)tetradeca-2,4-dien-8,10-diynamide

n-methyl-n-(2-methylpropyl)tetradeca-2,4-dien-8,10-diynamide

C19H27NO (285.2092532)


   

methyl dec-2-en-4,6,8-triynoate

methyl dec-2-en-4,6,8-triynoate

C11H8O2 (172.0524268)


   

(2e,4e)-n-(2-phenylethyl)undeca-2,4-dien-8,10-diynimidic acid

(2e,4e)-n-(2-phenylethyl)undeca-2,4-dien-8,10-diynimidic acid

C19H19NO (277.1466564)


   

(2e,4e)-n-[2-(4-hydroxyphenyl)ethyl]tetradeca-2,4-dienimidic acid

(2e,4e)-n-[2-(4-hydroxyphenyl)ethyl]tetradeca-2,4-dienimidic acid

C22H33NO2 (343.25111580000004)


   

(2e)-n-methyl-n-(2-methylpropyl)dec-2-en-4,6-diynamide

(2e)-n-methyl-n-(2-methylpropyl)dec-2-en-4,6-diynamide

C15H21NO (231.1623056)


   

n-(2-phenylethyl)undeca-2,4-dien-8,10-diynimidic acid

n-(2-phenylethyl)undeca-2,4-dien-8,10-diynimidic acid

C19H19NO (277.1466564)


   

n-[2-(4-hydroxyphenyl)ethyl]tetradeca-2,4-dienimidic acid

n-[2-(4-hydroxyphenyl)ethyl]tetradeca-2,4-dienimidic acid

C22H33NO2 (343.25111580000004)


   

(6e)-tetradec-6-en-8,10,12-triyn-3-one

(6e)-tetradec-6-en-8,10,12-triyn-3-one

C14H14O (198.1044594)


   

trideca-3,5-dien-7,9,11-triyn-1-ol

trideca-3,5-dien-7,9,11-triyn-1-ol

C13H12O (184.08881019999998)


   

(2e,4e)-n-(2-methylpropyl)deca-2,4-dienimidic acid

(2e,4e)-n-(2-methylpropyl)deca-2,4-dienimidic acid

C14H25NO (223.193604)


   

n-methyl-n-(2-methylpropyl)dec-2-en-4,6-diynamide

n-methyl-n-(2-methylpropyl)dec-2-en-4,6-diynamide

C15H21NO (231.1623056)


   

(2e,4e,12z)-n-(2-methylpropyl)tetradeca-2,4,12-trien-8,10-diynimidic acid

(2e,4e,12z)-n-(2-methylpropyl)tetradeca-2,4,12-trien-8,10-diynimidic acid

C18H23NO (269.1779548)


   

(2e,4e)-n-[2-(4-hydroxyphenyl)ethyl]dodeca-2,4-dienimidic acid

(2e,4e)-n-[2-(4-hydroxyphenyl)ethyl]dodeca-2,4-dienimidic acid

C20H29NO2 (315.2198174)


   

(2e,4e)-n-(2-methylpropyl)dodeca-2,4-dienimidic acid

(2e,4e)-n-(2-methylpropyl)dodeca-2,4-dienimidic acid

C16H29NO (251.2249024)


   

(2e,4e)-n-methyl-n-(2-methylpropyl)tetradeca-2,4-dien-8,10-diynamide

(2e,4e)-n-methyl-n-(2-methylpropyl)tetradeca-2,4-dien-8,10-diynamide

C19H27NO (285.2092532)


   

n-[2-(4-hydroxyphenyl)ethyl]deca-2,4-dienimidic acid

n-[2-(4-hydroxyphenyl)ethyl]deca-2,4-dienimidic acid

C18H25NO2 (287.188519)


   

n-(2-methylpropyl)dodeca-2,4-dien-8,10-diynimidic acid

n-(2-methylpropyl)dodeca-2,4-dien-8,10-diynimidic acid

C16H21NO (243.1623056)


   

n-[2-(4-hydroxyphenyl)ethyl]dodeca-2,4-dienimidic acid

n-[2-(4-hydroxyphenyl)ethyl]dodeca-2,4-dienimidic acid

C20H29NO2 (315.2198174)


   

(2e,4e)-n-(2-methylpropyl)dodeca-2,4-dien-8,10-diynimidic acid

(2e,4e)-n-(2-methylpropyl)dodeca-2,4-dien-8,10-diynimidic acid

C16H21NO (243.1623056)


   

(2e,4e)-n-[2-(4-hydroxyphenyl)ethyl]deca-2,4-dienimidic acid

(2e,4e)-n-[2-(4-hydroxyphenyl)ethyl]deca-2,4-dienimidic acid

C18H25NO2 (287.188519)