NCBI Taxonomy: 63026

Phlojodicarpus (ncbi_taxid: 63026)

found 56 associated metabolites at genus taxonomy rank level.

Ancestor: Selineae

Child Taxonomies: Phlojodicarpus popovii, Phlojodicarpus villosus, Phlojodicarpus sibiricus

Decursin

CROTONIC ACID, 3-METHYL-, ESTER WITH 7,8-DIHYDRO-7-HYDROXY-8,8-DIMETHYL-2H,6H-BENZO(1,2-B:5,4-B)DIPYRAN-2-ONE, (+)-

C19H20O5 (328.13106700000003)


Decursin is a member of coumarins. Decursin is a natural product found in Scutellaria lateriflora, Angelica glauca, and other organisms with data available. See also: Angelica gigas root (part of). D020536 - Enzyme Activators Decursinol angelate is a natural product found in Angelica glauca and Angelica gigas with data available. See also: Angelica gigas root (part of). Decursin ((+)-Decursin) is a potent anti-tumor agent. Decursin also is a cytotoxic agent and a potent protein kinase C activator. Decursin induces apoptosis and cell cycle arrest at G1 phase. Decursin decreases the expression of CDK2, CDK4, CDK6, cyclin D1 protein at 48 h. Decursin inhibits cell proliferation and migration. Decursin shows anti-tumor, anti-inflammatory and analgesic activities[1][2][3][4]. Decursin ((+)-Decursin) is a potent anti-tumor agent. Decursin also is a cytotoxic agent and a potent protein kinase C activator. Decursin induces apoptosis and cell cycle arrest at G1 phase. Decursin decreases the expression of CDK2, CDK4, CDK6, cyclin D1 protein at 48 h. Decursin inhibits cell proliferation and migration. Decursin shows anti-tumor, anti-inflammatory and analgesic activities[1][2][3][4]. Decursinol angelate, a cytotoxic and protein kinase C (PKC) activating agent from the root of Angelica gigas, possesses anti-tumor and anti-inflammatory activities[1][2].

   

Aegelinol

2-butenoic acid, 2-methyl-, (7S)-7,8-dihydro-8,8-dimethyl-2-oxo-2H,6H-benzo(1,2-b:5,4-b)dipyran-7-yl ester, (2Z)-

C14H14O4 (246.0892044)


Decursinol is an organic heterotricyclic compound that is 7,8-dihydro-2H,6H-pyrano[3,2-g]chromen-2-one substituted by a beta-hydroxy group at position 7 and two methyl groups at position 8. It is isolated from the roots of Angelica gigas and has been found to possess significant inhibitory activity against acetylcholinesterase enzyme (EC 3.1.1.7). It has a role as an EC 3.1.1.7 (acetylcholinesterase) inhibitor, an antineoplastic agent, an analgesic and a metabolite. It is an organic heterotricyclic compound, a delta-lactone, a secondary alcohol and a cyclic ether. Decursinol is a natural product found in Smyrniopsis aucheri, Phlojodicarpus villosus, and other organisms with data available. Aegelinol is found in fruits. Aegelinol is obtained from Aegle marmelos (bael fruit). obtained from Aegle marmelos (bael fruit). Aegelinol is found in fruits. D020536 - Enzyme Activators (±)-Decursinol is a potent FtsZ inhibitor. (±)-Decursinol inhibits B. anthracis FtsZ polymerization with an IC50 of 102 μM[1]. (±)-Decursinol is a potent FtsZ inhibitor. (±)-Decursinol inhibits B. anthracis FtsZ polymerization with an IC50 of 102 μM[1]. Decursinol, isolated from the roots of Angelica gigas, possesses antinociceptive effect with orally bioavailability. Decursinol possesses anti-tumor and anti-metastasis activity[1]. Decursinol, isolated from the roots of Angelica gigas, possesses antinociceptive effect with orally bioavailability. Decursinol possesses anti-tumor and anti-metastasis activity[1].

   

Dihydrosamidin

rac Dihydro Samidin

C21H24O7 (388.1521954)


Coumarins

   

Decursin

5,5-dimethyl-13-oxo-4,14-dioxatricyclo[8.4.0.0³,⁸]tetradeca-1(10),2,8,11-tetraen-6-yl 3-methylbut-2-enoate

C19H20O5 (328.13106700000003)


   

7-Hydroxychromone

7-hydroxy-4H-chromen-4-one

C9H6O3 (162.03169259999999)


7-Hydroxychromone is a Src kinase inhibitor with an IC50 of <300 μM. 7-Hydroxychromone is a Src kinase inhibitor with an IC50 of <300 μM.

   

Aegelinol

12-hydroxy-13,13-dimethyl-4,14-dioxatricyclo[8.4.0.0³,⁸]tetradeca-1(10),2,6,8-tetraen-5-one

C14H14O4 (246.0892044)


Aegelinol is a member of coumarins. Aegelinol is a natural product found in Phlojodicarpus villosus and Angelica gigas with data available. Aegelinol is found in fruits. Aegelinol is obtained from Aegle marmelos (bael fruit). obtained from Aegle marmelos (bael fruit). Aegelinol is found in fruits. (±)-Decursinol is a potent FtsZ inhibitor. (±)-Decursinol inhibits B. anthracis FtsZ polymerization with an IC50 of 102 μM[1]. (±)-Decursinol is a potent FtsZ inhibitor. (±)-Decursinol inhibits B. anthracis FtsZ polymerization with an IC50 of 102 μM[1].

   

Aegelinol

12-hydroxy-13,13-dimethyl-4,14-dioxatricyclo[8.4.0.0^{3,8}]tetradeca-1(10),2,6,8-tetraen-5-one

C14H14O4 (246.0892044)


(±)-Decursinol is a potent FtsZ inhibitor. (±)-Decursinol inhibits B. anthracis FtsZ polymerization with an IC50 of 102 μM[1]. (±)-Decursinol is a potent FtsZ inhibitor. (±)-Decursinol inhibits B. anthracis FtsZ polymerization with an IC50 of 102 μM[1].

   

decursinol

(7S)-7-hydroxy-8,8-dimethyl-6,7-dihydropyrano[5,6-g]chromen-2-one

C14H14O4 (246.0892044)


D020536 - Enzyme Activators Decursinol, isolated from the roots of Angelica gigas, possesses antinociceptive effect with orally bioavailability. Decursinol possesses anti-tumor and anti-metastasis activity[1]. Decursinol, isolated from the roots of Angelica gigas, possesses antinociceptive effect with orally bioavailability. Decursinol possesses anti-tumor and anti-metastasis activity[1].

   

Smirino

2-butenoic acid, 2-methyl-, (7S)-7,8-dihydro-8,8-dimethyl-2-oxo-2H,6H-benzo(1,2-b:5,4-b)dipyran-7-yl ester, (2Z)-

C14H14O4 (246.0892044)


Decursinol is an organic heterotricyclic compound that is 7,8-dihydro-2H,6H-pyrano[3,2-g]chromen-2-one substituted by a beta-hydroxy group at position 7 and two methyl groups at position 8. It is isolated from the roots of Angelica gigas and has been found to possess significant inhibitory activity against acetylcholinesterase enzyme (EC 3.1.1.7). It has a role as an EC 3.1.1.7 (acetylcholinesterase) inhibitor, an antineoplastic agent, an analgesic and a metabolite. It is an organic heterotricyclic compound, a delta-lactone, a secondary alcohol and a cyclic ether. Decursinol is a natural product found in Smyrniopsis aucheri, Phlojodicarpus villosus, and other organisms with data available. An organic heterotricyclic compound that is 7,8-dihydro-2H,6H-pyrano[3,2-g]chromen-2-one substituted by a beta-hydroxy group at position 7 and two methyl groups at position 8. It is isolated from the roots of Angelica gigas and has been found to possess significant inhibitory activity against acetylcholinesterase enzyme (EC 3.1.1.7). D020536 - Enzyme Activators Decursinol, isolated from the roots of Angelica gigas, possesses antinociceptive effect with orally bioavailability. Decursinol possesses anti-tumor and anti-metastasis activity[1]. Decursinol, isolated from the roots of Angelica gigas, possesses antinociceptive effect with orally bioavailability. Decursinol possesses anti-tumor and anti-metastasis activity[1].

   

7-Hydroxy-4-benzopyrone

7-hydroxy-4H-chromen-4-one

C9H6O3 (162.03169259999999)


7-Hydroxychromone is a Src kinase inhibitor with an IC50 of <300 μM. 7-Hydroxychromone is a Src kinase inhibitor with an IC50 of <300 μM.

   

10-(acetyloxy)-8,8-dimethyl-2-oxo-9h,10h-pyrano[2,3-h]chromen-9-yl 3-methylbutanoate

10-(acetyloxy)-8,8-dimethyl-2-oxo-9h,10h-pyrano[2,3-h]chromen-9-yl 3-methylbutanoate

C21H24O7 (388.1521954)


   

(3s)-9,9-dimethyl-2-oxo-3h,4h-pyrano[2,3-g]chromen-3-yl (2e)-2-methylbut-2-enoate

(3s)-9,9-dimethyl-2-oxo-3h,4h-pyrano[2,3-g]chromen-3-yl (2e)-2-methylbut-2-enoate

C19H20O5 (328.13106700000003)


   

7-hydroxy-8,8-dimethyl-6h,7h-pyrano[3,2-g]chromen-2-one

7-hydroxy-8,8-dimethyl-6h,7h-pyrano[3,2-g]chromen-2-one

C14H14O4 (246.0892044)


   

7-{[6-({[3,4-dihydroxy-4-(hydroxymethyl)oxolan-2-yl]oxy}methyl)-3,4,5-trihydroxyoxan-2-yl]oxy}chromen-2-one

7-{[6-({[3,4-dihydroxy-4-(hydroxymethyl)oxolan-2-yl]oxy}methyl)-3,4,5-trihydroxyoxan-2-yl]oxy}chromen-2-one

C20H24O12 (456.1267704)


   

8-[3-(2-hydroxypropan-2-yl)oxiran-2-yl]-7-methoxychromen-2-one

8-[3-(2-hydroxypropan-2-yl)oxiran-2-yl]-7-methoxychromen-2-one

C15H16O5 (276.0997686)


   

(3s)-9,9-dimethyl-2-oxo-3h,4h-pyrano[2,3-g]chromen-3-yl 2-methylbut-2-enoate

(3s)-9,9-dimethyl-2-oxo-3h,4h-pyrano[2,3-g]chromen-3-yl 2-methylbut-2-enoate

C19H20O5 (328.13106700000003)


   

9,9-dimethyl-2-oxo-3h,4h-pyrano[2,3-g]chromen-3-yl (2z)-2-methylbut-2-enoate

9,9-dimethyl-2-oxo-3h,4h-pyrano[2,3-g]chromen-3-yl (2z)-2-methylbut-2-enoate

C19H20O5 (328.13106700000003)


   

7-{[(2s,3r,4s,5s,6r)-6-({[(2r,3r,4r)-3,4-dihydroxy-4-(hydroxymethyl)oxolan-2-yl]oxy}methyl)-3,4,5-trihydroxyoxan-2-yl]oxy}chromen-2-one

7-{[(2s,3r,4s,5s,6r)-6-({[(2r,3r,4r)-3,4-dihydroxy-4-(hydroxymethyl)oxolan-2-yl]oxy}methyl)-3,4,5-trihydroxyoxan-2-yl]oxy}chromen-2-one

C20H24O12 (456.1267704)