NCBI Taxonomy: 507406
Combretum erythrophyllum (ncbi_taxid: 507406)
found 3 associated metabolites at species taxonomy rank level.
Ancestor: Combretum
Child Taxonomies: none taxonomy data.
Combretastatin_A-4
phenol, 2-methoxy-5-((1z)-2-(3,4,5-trimethoxyphenyl)ethenyl)-,1-(dihydrogen phosphate)
Combretastatin A4 is a stilbenoid. Combretastatin A4 is a natural product found in Combretum caffrum with data available. Combretastatin A-4 is an inhibitor of microtubule polymerization derived from the South African willow bush which causes mitotic arrest and selectively targets and reduces or destroys existing blood vessels, causing decreased tumor blood supply. C274 - Antineoplastic Agent > C186664 - Cytotoxic Chemotherapeutic Agent > C273 - Antimitotic Agent D000970 - Antineoplastic Agents Combretastatin A4 is a microtubule-targeting agent that binds β-tubulin with Kd of 0.4 μM.
(2s)-6-methyl-2-[(1s,3r,8r,11s,12s,15r,16s)-7,7,12,16-tetramethyl-6-oxopentacyclo[9.7.0.0¹,³.0³,⁸.0¹²,¹⁶]octadeca-4,17-dien-15-yl]hept-5-enoic acid
(2s)-6-methyl-2-[(1s,3r,8r,11s,12s,15r,16s)-7,7,12,16-tetramethyl-6-oxopentacyclo[9.7.0.0¹,³.0³,⁸.0¹²,¹⁶]octadeca-4,17-dien-15-yl]hept-5-enoic acid
(2r)-6-methyl-2-[(1r,3s,8r,11s,12s,15r,16r)-7,7,12,16-tetramethyl-6-oxopentacyclo[9.7.0.0¹,³.0³,⁸.0¹²,¹⁶]octadeca-4,17-dien-15-yl]hept-5-enoic acid
(2r)-6-methyl-2-[(1r,3s,8r,11s,12s,15r,16r)-7,7,12,16-tetramethyl-6-oxopentacyclo[9.7.0.0¹,³.0³,⁸.0¹²,¹⁶]octadeca-4,17-dien-15-yl]hept-5-enoic acid
