NCBI Taxonomy: 5008

Taphrinales (ncbi_taxid: 5008)

found 18 associated metabolites at order taxonomy rank level.

Ancestor: Taphrinomycetes

Child Taxonomies: Taphrinaceae, Protomycetaceae, environmental samples, unclassified Taphrinales, Taphrinales incertae sedis

Brassicasterol

(1S,2R,5S,10S,11S,14R,15R)-14-[(2R,3E,5R)-5,6-dimethylhept-3-en-2-yl]-2,15-dimethyltetracyclo[8.7.0.0^{2,7}.0^{11,15}]heptadec-7-en-5-ol

C28H46O (398.3548466)


Brassicasterol belongs to the class of organic compounds known as ergosterols and derivatives. These are steroids containing ergosta-5,7,22-trien-3beta-ol or a derivative thereof, which is based on the 3beta-hydroxylated ergostane skeleton. Thus, brassicasterol is considered to be a sterol lipid molecule. Brassicasterol is a very hydrophobic molecule, practically insoluble (in water), and relatively neutral. Brassicasterol is a potential CSF biomarker for Alzheimer’s disease (PMID: 21585343). C1907 - Drug, Natural Product > C28178 - Phytosterol > C68437 - Unsaturated Phytosterol Constituent of Brassica rapa oil Brassicasterol, a metabolite of Ergosterol, plays a role in the inhibitory effect on bladder carcinogenesis promotion via androgen signaling[1]. Brassicasterol shows dual anti-infective properties against HSV-1 (IC50=1.2 μM) and Mycobacterium tuberculosis, and cardiovascular protective effect[2]. Brassicasterol exerts an anti-cancer effect by dual-targeting AKT and androgen receptor signaling in prostate cancer[3]. Brassicasterol is a metabolite of Ergosterol and has cardiovascular protective effects. Brassicasterol exerts anticancer effects in prostate cancer through dual targeting of AKT and androgen receptor signaling pathways. Brassicasterol inhibits HSV-1 (IC50=1.2 μM) and Mycobacterium tuberculosis. Brassicasterol also inhibits sterol δ 24-reductase, slowing the progression of atherosclerosis. Brassicasterol is also a cerebrospinal fluid biomarker for Alzheimer's disease[1][2][3][4][5][6]. Brassicasterol, a metabolite of Ergosterol, plays a role in the inhibitory effect on bladder carcinogenesis promotion via androgen signaling[1]. Brassicasterol shows dual anti-infective properties against HSV-1 (IC50=1.2 μM) and Mycobacterium tuberculosis, and cardiovascular protective effect[2]. Brassicasterol exerts an anti-cancer effect by dual-targeting AKT and androgen receptor signaling in prostate cancer[3].

   

Brassicasterol

ergosta-5,22E-dien-3beta-ol

C28H46O (398.3548466)


An 3beta-sterol that is (22E)-ergosta-5,22-diene substituted by a hydroxy group at position 3beta. It is a phytosterol found in marine algae, fish, and rapeseed oil. C1907 - Drug, Natural Product > C28178 - Phytosterol > C68437 - Unsaturated Phytosterol Disclaimer: While authors make an effort to ensure that the content of this record is accurate, the authors make no representations or warranties in relation to the accuracy or completeness of the record. This record do not reflect any viewpoints of the affiliation and organization to which the authors belong. Brassicasterol, a metabolite of Ergosterol, plays a role in the inhibitory effect on bladder carcinogenesis promotion via androgen signaling[1]. Brassicasterol shows dual anti-infective properties against HSV-1 (IC50=1.2 μM) and Mycobacterium tuberculosis, and cardiovascular protective effect[2]. Brassicasterol exerts an anti-cancer effect by dual-targeting AKT and androgen receptor signaling in prostate cancer[3]. Brassicasterol is a metabolite of Ergosterol and has cardiovascular protective effects. Brassicasterol exerts anticancer effects in prostate cancer through dual targeting of AKT and androgen receptor signaling pathways. Brassicasterol inhibits HSV-1 (IC50=1.2 μM) and Mycobacterium tuberculosis. Brassicasterol also inhibits sterol δ 24-reductase, slowing the progression of atherosclerosis. Brassicasterol is also a cerebrospinal fluid biomarker for Alzheimer's disease[1][2][3][4][5][6]. Brassicasterol, a metabolite of Ergosterol, plays a role in the inhibitory effect on bladder carcinogenesis promotion via androgen signaling[1]. Brassicasterol shows dual anti-infective properties against HSV-1 (IC50=1.2 μM) and Mycobacterium tuberculosis, and cardiovascular protective effect[2]. Brassicasterol exerts an anti-cancer effect by dual-targeting AKT and androgen receptor signaling in prostate cancer[3].

   

(2r,3r,5r,7s)-2-hydroxy-5-(2-hydroxypropan-2-yl)-11,11-dimethyl-4,10-dioxatricyclo[7.4.0.0³,⁷]tridec-1(9)-en-13-one

(2r,3r,5r,7s)-2-hydroxy-5-(2-hydroxypropan-2-yl)-11,11-dimethyl-4,10-dioxatricyclo[7.4.0.0³,⁷]tridec-1(9)-en-13-one

C16H24O5 (296.1623654)


   

(7r,8r)-7-hydroxy-3,7-dimethyl-6-oxo-8-[(3e)-2-oxoundec-3-en-1-yl]-8h-isochromene-5-carboxylic acid

(7r,8r)-7-hydroxy-3,7-dimethyl-6-oxo-8-[(3e)-2-oxoundec-3-en-1-yl]-8h-isochromene-5-carboxylic acid

C23H30O6 (402.204228)


   

(2r,3as,7ar)-2-(2-hydroxypropan-2-yl)-6-(3-methylbut-2-en-1-yl)-3,3a,4,7a-tetrahydro-2h-1-benzofuran-5-one

(2r,3as,7ar)-2-(2-hydroxypropan-2-yl)-6-(3-methylbut-2-en-1-yl)-3,3a,4,7a-tetrahydro-2h-1-benzofuran-5-one

C16H24O3 (264.1725354)


   

2-[(2s)-2-{2-[(2s)-2-{2-[(2s)-2-{2-[(2s)-2-(2,4-dihydroxy-6-methylbenzoyloxy)propyl]-4,6-dihydroxybenzoyloxy}propyl]-4,6-dihydroxybenzoyloxy}propyl]-4,6-dihydroxybenzoyloxy}propyl]-4,6-dihydroxybenzoic acid

2-[(2s)-2-{2-[(2s)-2-{2-[(2s)-2-{2-[(2s)-2-(2,4-dihydroxy-6-methylbenzoyloxy)propyl]-4,6-dihydroxybenzoyloxy}propyl]-4,6-dihydroxybenzoyloxy}propyl]-4,6-dihydroxybenzoyloxy}propyl]-4,6-dihydroxybenzoic acid

C48H48O20 (944.2738807999999)


   

(5s)-4,5-dihydroxy-2-[(1e)-prop-1-en-1-yl]cyclopent-2-en-1-one

(5s)-4,5-dihydroxy-2-[(1e)-prop-1-en-1-yl]cyclopent-2-en-1-one

C8H10O3 (154.062991)


   

2-[(2s)-2-{2-[(2s)-2-{2-[(2s)-2-{2-[(2s)-2-{2-[(2s)-2-(2,4-dihydroxy-6-methylbenzoyloxy)propyl]-4,6-dihydroxybenzoyloxy}propyl]-4,6-dihydroxybenzoyloxy}propyl]-4,6-dihydroxybenzoyloxy}propyl]-4,6-dihydroxybenzoyloxy}propyl]-4,6-dihydroxybenzoic acid

2-[(2s)-2-{2-[(2s)-2-{2-[(2s)-2-{2-[(2s)-2-{2-[(2s)-2-(2,4-dihydroxy-6-methylbenzoyloxy)propyl]-4,6-dihydroxybenzoyloxy}propyl]-4,6-dihydroxybenzoyloxy}propyl]-4,6-dihydroxybenzoyloxy}propyl]-4,6-dihydroxybenzoyloxy}propyl]-4,6-dihydroxybenzoic acid

C58H58O24 (1138.3317868)


   

(2s,4r,6r,8s,9s)-9-hydroxy-6-(2-hydroxypropan-2-yl)-13,13-dimethyl-3,7,14-trioxatetracyclo[8.4.0.0²,⁴.0⁴,⁸]tetradec-1(10)-en-11-one

(2s,4r,6r,8s,9s)-9-hydroxy-6-(2-hydroxypropan-2-yl)-13,13-dimethyl-3,7,14-trioxatetracyclo[8.4.0.0²,⁴.0⁴,⁸]tetradec-1(10)-en-11-one

C16H22O6 (310.1416312)


   

2-[(2s)-2-{2-[(2s)-2-{2-[(2s)-2-(2,4-dihydroxy-6-methylbenzoyloxy)propyl]-4,6-dihydroxybenzoyloxy}propyl]-4,6-dihydroxybenzoyloxy}propyl]-4,6-dihydroxybenzoic acid

2-[(2s)-2-{2-[(2s)-2-{2-[(2s)-2-(2,4-dihydroxy-6-methylbenzoyloxy)propyl]-4,6-dihydroxybenzoyloxy}propyl]-4,6-dihydroxybenzoyloxy}propyl]-4,6-dihydroxybenzoic acid

C38H38O16 (750.2159748)


   
   

(4r,5s)-2-[(1z)-1-chloroprop-1-en-1-yl]-4,5-dihydroxycyclopent-2-en-1-one

(4r,5s)-2-[(1z)-1-chloroprop-1-en-1-yl]-4,5-dihydroxycyclopent-2-en-1-one

C8H9ClO3 (188.02401940000001)


   

(5s)-5-hydroxy-2,3-dimethylcyclopent-2-en-1-one

(5s)-5-hydroxy-2,3-dimethylcyclopent-2-en-1-one

C7H10O2 (126.068076)


   

(5r,5ar,7s,8as)-5-hydroxy-7-(2-hydroxypropan-2-yl)-2,2-dimethyl-3h,5h,5ah,6h,7h,8h,8ah,9h-indeno[5,6-b]pyran-4-one

(5r,5ar,7s,8as)-5-hydroxy-7-(2-hydroxypropan-2-yl)-2,2-dimethyl-3h,5h,5ah,6h,7h,8h,8ah,9h-indeno[5,6-b]pyran-4-one

C17H26O4 (294.1830996)


   

(3ar,6ar)-4-(2-ethenyl-4,4-dimethylcyclopent-1-en-1-yl)-tetrahydro-3h-furo[2,3-b]furan-2-one

(3ar,6ar)-4-(2-ethenyl-4,4-dimethylcyclopent-1-en-1-yl)-tetrahydro-3h-furo[2,3-b]furan-2-one

C15H20O3 (248.14123700000002)


   

(7r,8r)-7-hydroxy-3,7-dimethyl-6-oxo-8-(2-oxoundecyl)-8h-isochromene-5-carboxylic acid

(7r,8r)-7-hydroxy-3,7-dimethyl-6-oxo-8-(2-oxoundecyl)-8h-isochromene-5-carboxylic acid

C23H32O6 (404.2198772)


   

(7r,8r)-7-hydroxy-3,7-dimethyl-8-[(3e)-2-oxoundec-3-en-1-yl]-8h-isochromen-6-one

(7r,8r)-7-hydroxy-3,7-dimethyl-8-[(3e)-2-oxoundec-3-en-1-yl]-8h-isochromen-6-one

C22H30O4 (358.214398)


   

(1r,2r)-4-methyl-5-methylidenecyclopent-3-ene-1,2-diol

(1r,2r)-4-methyl-5-methylidenecyclopent-3-ene-1,2-diol

C7H10O2 (126.068076)