NCBI Taxonomy: 3026922

Spilanthes leiocarpa (ncbi_taxid: 3026922)

found 21 associated metabolites at species taxonomy rank level.

Ancestor: Spilanthes

Child Taxonomies: none taxonomy data.

Alantolactone

Naphtho(2,3-b)furan-2(3H)-one, 3a,5,6,7,8,8a,9,9a-octahydro-5,8a-dimethyl-3-methylene-, (3aR-(3a alpha,5beta,8a beta,9a alpha))-

C15H20O2 (232.14632200000003)


Alantolactone is a sesquiterpene lactone that is 3a,5,6,7,8,8a,9,9a-octahydronaphtho[2,3-b]furan-2-one bearing two methyl substituents at positions 5 and 8a as well as a methylidene substituent at position 3. It has a role as a plant metabolite, an apoptosis inducer and an antineoplastic agent. It is a sesquiterpene lactone, a naphthofuran and an olefinic compound. Alantolactone is a natural product found in Eupatorium cannabinum, Pentanema britannicum, and other organisms with data available. Alantolactone is found in herbs and spices. Alantolactone is a constituent of Inula helenium (elecampane) Constituent of Inula helenium (elecampane). Alantolactone is found in herbs and spices. Alantolactone is a selective STAT3 inhibitor, with potent anticancer activity. Alantolactone induces apoptosis in cancer[1][2][3]. Alantolactone is a selective STAT3 inhibitor, with potent anticancer activity. Alantolactone induces apoptosis in cancer[1][2][3].

   

Lupeol acetate

1,2,5,14,18,18-hexamethyl-8-(prop-1-en-2-yl)pentacyclo[11.8.0.0²,¹⁰.0⁵,⁹.0¹⁴,¹⁹]henicosan-17-yl acetate

C32H52O2 (468.3967092)


   

Lupeol acetate

Acetic acid (1R,3aR,4S,5aR,5bR,7aR,9S,11aR,11bR,13aR,13bR)-1-isopropenyl-3a,5a,5b,8,8,11a-hexamethyl-eicosahydro-cyclopenta[a]chrysen-9-yl ester

C32H52O2 (468.3967092)


Lupeol acetate, a derivative of Lupeol, suppresses the progression of rheumatoid arthritis (RA) by inhibiting the activation of macrophages and osteoclastogenesis through downregulations of TNF-α, IL-1β, MCP-1, COX-2, VEGF and granzyme B[1]. Lupeol acetate, a derivative of Lupeol, suppresses the progression of rheumatoid arthritis (RA) by inhibiting the activation of macrophages and osteoclastogenesis through downregulations of TNF-α, IL-1β, MCP-1, COX-2, VEGF and granzyme B[1].

   

Lupeol acetate

1,2,5,14,18,18-hexamethyl-8-(prop-1-en-2-yl)pentacyclo[11.8.0.0²,¹⁰.0⁵,⁹.0¹⁴,¹⁹]henicosan-17-yl acetate

C32H52O2 (468.3967092)


Lupeyl acetate, also known as lupeyl acetic acid, is a member of the class of compounds known as triterpenoids. Triterpenoids are terpene molecules containing six isoprene units. Lupeyl acetate is practically insoluble (in water) and an extremely weak basic (essentially neutral) compound (based on its pKa). Lupeyl acetate can be found in burdock, date, and fig, which makes lupeyl acetate a potential biomarker for the consumption of these food products. Lupeol acetate, a derivative of Lupeol, suppresses the progression of rheumatoid arthritis (RA) by inhibiting the activation of macrophages and osteoclastogenesis through downregulations of TNF-α, IL-1β, MCP-1, COX-2, VEGF and granzyme B[1]. Lupeol acetate, a derivative of Lupeol, suppresses the progression of rheumatoid arthritis (RA) by inhibiting the activation of macrophages and osteoclastogenesis through downregulations of TNF-α, IL-1β, MCP-1, COX-2, VEGF and granzyme B[1].

   

Igalan

Igalan

C15H20O2 (232.14632200000003)


A sesquiterpene lactone that is hexahydro-1-benzofuran-2(3H)-one substituted by a methyl group at position 6, methylene group at position 3, isopropenyl group at position 5 and a vinyl group at position 6. Isolated from Inula helenium and Rudbeckia laciniata, it exhibits antiproliferative activity.

   

6-ethenyl-6-methyl-3-methylidene-5-(prop-1-en-2-yl)-tetrahydro-3ah-1-benzofuran-2-one

6-ethenyl-6-methyl-3-methylidene-5-(prop-1-en-2-yl)-tetrahydro-3ah-1-benzofuran-2-one

C15H20O2 (232.14632200000003)


   

5,6-diethenyl-6-methyl-3-methylidene-tetrahydro-3ah-1-benzofuran-2-one

5,6-diethenyl-6-methyl-3-methylidene-tetrahydro-3ah-1-benzofuran-2-one

C14H18O2 (218.1306728)


   

(3ar,4ar,8as,9ar)-8a-methyl-3,5-dimethylidene-3ah,4h,4ah,6h,9h,9ah-naphtho[2,3-b]furan-2-one

(3ar,4ar,8as,9ar)-8a-methyl-3,5-dimethylidene-3ah,4h,4ah,6h,9h,9ah-naphtho[2,3-b]furan-2-one

C15H18O2 (230.1306728)


   

(1s,9s,10r,12s)-4-(hydroxymethyl)-9-methyl-13-methylidene-6-oxatetracyclo[7.4.0.0³,⁷.0¹⁰,¹²]trideca-3,7-dien-5-one

(1s,9s,10r,12s)-4-(hydroxymethyl)-9-methyl-13-methylidene-6-oxatetracyclo[7.4.0.0³,⁷.0¹⁰,¹²]trideca-3,7-dien-5-one

C15H16O3 (244.1099386)


   

(3ar,4ar,8ar,9ar)-8a-methyl-3,5-dimethylidene-3ah,4h,4ah,6h,9h,9ah-naphtho[2,3-b]furan-2-one

(3ar,4ar,8ar,9ar)-8a-methyl-3,5-dimethylidene-3ah,4h,4ah,6h,9h,9ah-naphtho[2,3-b]furan-2-one

C15H18O2 (230.1306728)


   

2,5,8-trimethyl-6-methylidenetricyclo[6.3.0.0¹,⁵]undecane

2,5,8-trimethyl-6-methylidenetricyclo[6.3.0.0¹,⁵]undecane

C15H24 (204.18779039999998)


   

(3ar,5s,6s,7ar)-5,6-diethenyl-6-methyl-3-methylidene-tetrahydro-3ah-1-benzofuran-2-one

(3ar,5s,6s,7ar)-5,6-diethenyl-6-methyl-3-methylidene-tetrahydro-3ah-1-benzofuran-2-one

C14H18O2 (218.1306728)


   

(3r,3ar,5r,6r,7ar)-6-ethenyl-3,6-dimethyl-5-(prop-1-en-2-yl)-hexahydro-1-benzofuran-2-one

(3r,3ar,5r,6r,7ar)-6-ethenyl-3,6-dimethyl-5-(prop-1-en-2-yl)-hexahydro-1-benzofuran-2-one

C15H22O2 (234.1619712)


   

(2r,5s,8s)-2,5,8-trimethyl-6-methylidenetricyclo[6.3.0.0¹,⁵]undecane

(2r,5s,8s)-2,5,8-trimethyl-6-methylidenetricyclo[6.3.0.0¹,⁵]undecane

C15H24 (204.18779039999998)


   

4-(hydroxymethyl)-9-methyl-13-methylidene-6-oxatetracyclo[7.4.0.0³,⁷.0¹⁰,¹²]trideca-3,7-dien-5-one

4-(hydroxymethyl)-9-methyl-13-methylidene-6-oxatetracyclo[7.4.0.0³,⁷.0¹⁰,¹²]trideca-3,7-dien-5-one

C15H16O3 (244.1099386)


   

8a-methyl-3,5-dimethylidene-3ah,4h,4ah,6h,9h,9ah-naphtho[2,3-b]furan-2-one

8a-methyl-3,5-dimethylidene-3ah,4h,4ah,6h,9h,9ah-naphtho[2,3-b]furan-2-one

C15H18O2 (230.1306728)


   

6-ethenyl-3,6-dimethyl-5-(prop-1-en-2-yl)-hexahydro-1-benzofuran-2-one

6-ethenyl-3,6-dimethyl-5-(prop-1-en-2-yl)-hexahydro-1-benzofuran-2-one

C15H22O2 (234.1619712)


   

(1r,9s,10r,12s)-4-(hydroxymethyl)-9-methyl-13-methylidene-6-oxatetracyclo[7.4.0.0³,⁷.0¹⁰,¹²]trideca-3,7-dien-5-one

(1r,9s,10r,12s)-4-(hydroxymethyl)-9-methyl-13-methylidene-6-oxatetracyclo[7.4.0.0³,⁷.0¹⁰,¹²]trideca-3,7-dien-5-one

C15H16O3 (244.1099386)


   

(1s,2s,5r,8r)-2,5,8-trimethyl-6-methylidenetricyclo[6.3.0.0¹,⁵]undecane

(1s,2s,5r,8r)-2,5,8-trimethyl-6-methylidenetricyclo[6.3.0.0¹,⁵]undecane

C15H24 (204.18779039999998)


   

3a,5a,5b,8,8,11a-hexamethyl-1-(prop-1-en-2-yl)-hexadecahydrocyclopenta[a]chrysen-9-yl acetate

3a,5a,5b,8,8,11a-hexamethyl-1-(prop-1-en-2-yl)-hexadecahydrocyclopenta[a]chrysen-9-yl acetate

C32H52O2 (468.3967092)