NCBI Taxonomy: 1905151

Streptomyces asenjonii (ncbi_taxid: 1905151)

found 8 associated metabolites at species taxonomy rank level.

Ancestor: Streptomyces

Child Taxonomies: none taxonomy data.

brevianamide F

brevianamide F

C16H17N3O2 (283.1320702)


A pyrrolopyrazine that is hexahydropyrrolo[1,2-a]pyrazine-1,4-dione bearing an indol-3-ylmethyl substituent at position 3 (the 3S,8aS-diastereomer, obtained by formal cyclocondensation of L-tryptophan and L-proline). Brevianamide F (Cyclo(L-Pro-L-Trp)) is a mycotoxin isolated from Colletotrichum gloeosporioides, with antibacterial activity. Brevianamide F shows potent PI3Kα inhibitory activity with an IC50 of 4.8 μM[1][2].

   

2-amino-4-butyl-2,5-dimethylcyclopent-4-ene-1,3-dione

2-amino-4-butyl-2,5-dimethylcyclopent-4-ene-1,3-dione

C11H17NO2 (195.12592220000002)