NCBI Taxonomy: 1847
Pseudonocardia (ncbi_taxid: 1847)
found 54 associated metabolites at genus taxonomy rank level.
Ancestor: Pseudonocardiaceae
Child Taxonomies: Pseudonocardia alni, Pseudonocardia saturnea, Pseudonocardia compacta, Pseudonocardia pini, Pseudonocardia soli, Pseudonocardia fici, Pseudonocardia nigra, Pseudonocardia lutea, Pseudonocardia lacus, Pseudonocardia oceani, Pseudonocardia humida, environmental samples, Pseudonocardia terrae, Pseudonocardia nitrificans, Pseudonocardia thermophila, Pseudonocardia halophobica, Pseudonocardia yunnanensis, Pseudonocardia tropica, Pseudonocardia acaciae, Pseudonocardia spinosa, Pseudonocardia oroxyli, Pseudonocardia tritici, Pseudonocardia autotrophica, Pseudonocardia cypriaca, Pseudonocardia mangrovi, Pseudonocardia parietis, Pseudonocardia babensis, Pseudonocardia kujensis, Pseudonocardia petroleophila, Pseudonocardia sulfidoxydans, Pseudonocardia eucalypti, Pseudonocardia abyssalis, Pseudonocardia acidicola, Pseudonocardia sediminis, Pseudonocardia bannensis, Pseudonocardia aurantiaca, Pseudonocardia artemisiae, Pseudonocardia antarctica, Pseudonocardia rhizophila, Pseudonocardia seranimata, Pseudonocardia cytotoxica, Pseudonocardia asaccharolytica, Pseudonocardia zijingensis, Pseudonocardia endophytica, Pseudonocardia kongjuensis, Pseudonocardia ailaonensis, Pseudonocardia xishanensis, Pseudonocardia callicarpae, Pseudonocardia salamisensis, Pseudonocardia spinosispora, Pseudonocardia mongoliensis, Pseudonocardia alaniniphila, Pseudonocardia adelaidensis, Pseudonocardia sichuanensis, unclassified Pseudonocardia, Pseudonocardia nantongensis, Pseudonocardia kunmingensis, Pseudonocardia nematodicida, Pseudonocardia hispaniensis, Pseudonocardia yuanmonensis, Pseudonocardia broussonetiae, Pseudonocardia xinjiangensis, Pseudonocardia khuvsgulensis, Pseudonocardia dioxanivorans, Pseudonocardia antitumoralis, Pseudonocardia benzenivorans, Pseudonocardia profundimaris, Pseudonocardia antimicrobica, Pseudonocardia thailandensis, Pseudonocardia hierapolitana, Pseudonocardia ammonioxydans, Pseudonocardia carboxydivorans, Pseudonocardia chloroethenivorans, Pseudonocardia hydrocarbonoxydans, Pseudonocardia tetrahydrofuranoxydans
Protocatechuic acid
Protocatechuic acid, also known as protocatechuate or 3,4-dihydroxybenzoate, belongs to the class of organic compounds known as hydroxybenzoic acid derivatives. Hydroxybenzoic acid derivatives are compounds containing a hydroxybenzoic acid (or a derivative), which is a benzene ring bearing a carboxyl and a hydroxyl groups. The enzyme protocatechuate 3,4-dioxygenase uses 3,4-dihydroxybenzoate and O2 to produce 3-carboxy-cis,cis-muconate. Protocatechuic acid is a drug. In the analogous hardening of the cockroach ootheca, the phenolic substance concerned is protocatechuic acid. Protocatechuic acid is a mild, balsamic, and phenolic tasting compound. Outside of the human body, protocatechuic acid is found, on average, in the highest concentration in a few different foods, such as garden onions, cocoa powders, and star anises and in a lower concentration in lentils, liquors, and red raspberries. Protocatechuic acid has also been detected, but not quantified in several different foods, such as cloud ear fungus, american pokeweeds, common mushrooms, fruits, and feijoa. This could make protocatechuic acid a potential biomarker for the consumption of these foods. It is also found in Allium cepa (17,540 ppm). It is a major metabolite of antioxidant polyphenols found in green tea. Similarly, PCA was reported to increase proliferation and inhibit apoptosis of neural stem cells. In vitro testing documented antioxidant and anti-inflammatory activity of PCA, while liver protection in vivo was measured by chemical markers and histological assessment. 3,4-dihydroxybenzoic acid, also known as protocatechuic acid or 4-carboxy-1,2-dihydroxybenzene, belongs to hydroxybenzoic acid derivatives class of compounds. Those are compounds containing a hydroxybenzoic acid (or a derivative), which is a benzene ring bearing a carboxyl and a hydroxyl groups. 3,4-dihydroxybenzoic acid is soluble (in water) and a weakly acidic compound (based on its pKa). 3,4-dihydroxybenzoic acid can be synthesized from benzoic acid. 3,4-dihydroxybenzoic acid is also a parent compound for other transformation products, including but not limited to, methyl 3,4-dihydroxybenzoate, ethyl 3,4-dihydroxybenzoate, and 1-(3,4-dihydroxybenzoyl)-beta-D-glucopyranose. 3,4-dihydroxybenzoic acid is a mild, balsamic, and phenolic tasting compound and can be found in a number of food items such as white mustard, grape wine, abalone, and asian pear, which makes 3,4-dihydroxybenzoic acid a potential biomarker for the consumption of these food products. 3,4-dihydroxybenzoic acid can be found primarily in blood, feces, and urine, as well as in human fibroblasts and testes tissues. 3,4-dihydroxybenzoic acid exists in all eukaryotes, ranging from yeast to humans. Protocatechuic acid (PCA) is a dihydroxybenzoic acid, a type of phenolic acid. It is a major metabolite of antioxidant polyphenols found in green tea. It has mixed effects on normal and cancer cells in in vitro and in vivo studies . 3,4-dihydroxybenzoic acid is a dihydroxybenzoic acid in which the hydroxy groups are located at positions 3 and 4. It has a role as a human xenobiotic metabolite, a plant metabolite, an antineoplastic agent, an EC 1.1.1.25 (shikimate dehydrogenase) inhibitor and an EC 1.14.11.2 (procollagen-proline dioxygenase) inhibitor. It is a member of catechols and a dihydroxybenzoic acid. It is functionally related to a benzoic acid. It is a conjugate acid of a 3,4-dihydroxybenzoate. 3,4-Dihydroxybenzoic acid is a natural product found in Visnea mocanera, Amomum subulatum, and other organisms with data available. Protocatechuic acid is a metabolite found in or produced by Saccharomyces cerevisiae. See also: Black Cohosh (part of); Vaccinium myrtillus Leaf (part of); Menyanthes trifoliata leaf (part of) ... View More ... A dihydroxybenzoic acid in which the hydroxy groups are located at positions 3 and 4. Protocatechuic acid. CAS Common Chemistry. CAS, a division of the American Chemical Society, n.d. https://commonchemistry.cas.org/detail?cas_rn=99-50-3 (retrieved 2024-06-29) (CAS RN: 99-50-3). Licensed under the Attribution-Noncommercial 4.0 International License (CC BY-NC 4.0). Protocatechuic acid is a phenolic compound which exhibits neuroprotective effect. Protocatechuic acid is a phenolic compound which exhibits neuroprotective effect.
99-50-3
D020011 - Protective Agents > D016588 - Anticarcinogenic Agents D000970 - Antineoplastic Agents Protocatechuic acid is a phenolic compound which exhibits neuroprotective effect. Protocatechuic acid is a phenolic compound which exhibits neuroprotective effect.
