NCBI Taxonomy: 1707443

Pittocaulon filare (ncbi_taxid: 1707443)

found 23 associated metabolites at species taxonomy rank level.

Ancestor: Pittocaulon

Child Taxonomies: none taxonomy data.

Senecionine

(1,6)Dioxacyclododecino(2,3,4-gh)pyrrolizine-2,7-dione, 3-ethylidene-3,4,5,6,9,11,13,14,14a,14b-decahydro-6-hydroxy-5,6-dimethyl-, (3Z,5R,6R,14aR,14bR)-

C18H25NO5 (335.1733)


Senecionine is a pyrrolizidine alkaloid isolated from the plant species of the genus Senecio. It has a role as a plant metabolite. It is a lactone, a pyrrolizidine alkaloid and a tertiary alcohol. It is functionally related to a senecionan. It is a conjugate base of a senecionine(1+). Senecionine is a natural product found in Dorobaea pimpinellifolia, Crotalaria micans, and other organisms with data available. Senecionine is an organic compound with the chemical formula C18H25NO5. It is classified as a pyrrolizidine alkaloid. See also: Petasites hybridus root (part of); Tussilago farfara flower (part of); Tussilago farfara leaf (part of). A pyrrolizidine alkaloid isolated from the plant species of the genus Senecio. D000970 - Antineoplastic Agents Annotation level-1 CONFIDENCE Reference Standard (Level 1); INTERNAL_ID 2251 CONFIDENCE Reference Standard (Level 1); INTERNAL_ID 122 CONFIDENCE Reference Standard (Level 1); INTERNAL_ID 102 CONFIDENCE Reference Standard (Level 1); INTERNAL_ID 142 CONFIDENCE Reference Standard (Level 1); INTERNAL_ID 152 CONFIDENCE Reference Standard (Level 1); INTERNAL_ID 162 CONFIDENCE Reference Standard (Level 1); INTERNAL_ID 172 CONFIDENCE Reference Standard (Level 1); INTERNAL_ID 132 CONFIDENCE Reference Standard (Level 1); INTERNAL_ID 112 [Raw Data] CB082a_Senecionine_pos_40eV_CB000034.txt [Raw Data] CB082a_Senecionine_pos_10eV_CB000034.txt [Raw Data] CB082a_Senecionine_pos_30eV_CB000034.txt [Raw Data] CB082a_Senecionine_pos_20eV_CB000034.txt [Raw Data] CB082a_Senecionine_pos_50eV_CB000034.txt Senecionine (Senecionan-11,16-dione, 12-hydroxy-) is a pyrrolizidine alkaloid could be isolated from Senecio vulgaris. Senecionine decreases the activities of glutathione S-transferase, aminopyrine demethylase and arylhydrocarbon hydroxylase (AHH)[1][2][3]. Senecionine (Senecionan-11,16-dione, 12-hydroxy-) is a pyrrolizidine alkaloid could be isolated from Senecio vulgaris. Senecionine decreases the activities of glutathione S-transferase, aminopyrine demethylase and arylhydrocarbon hydroxylase (AHH)[1][2][3].

   

Senkirkin

Senkirkine

C19H27NO6 (365.1838)


CONFIDENCE Reference Standard (Level 1); INTERNAL_ID 178 CONFIDENCE Reference Standard (Level 1); INTERNAL_ID 168 CONFIDENCE Reference Standard (Level 1); INTERNAL_ID 158 CONFIDENCE Reference Standard (Level 1); INTERNAL_ID 148 CONFIDENCE Reference Standard (Level 1); INTERNAL_ID 138 INTERNAL_ID 138; CONFIDENCE Reference Standard (Level 1) CONFIDENCE Reference Standard (Level 1); INTERNAL_ID 128 CONFIDENCE Reference Standard (Level 1); INTERNAL_ID 118 CONFIDENCE Reference Standard (Level 1); INTERNAL_ID 108 INTERNAL_ID 2283; CONFIDENCE Reference Standard (Level 1) CONFIDENCE Reference Standard (Level 1); INTERNAL_ID 2283

   

Integerrimine

4-ethylidene-7-hydroxy-6,7-dimethyl-2,9-dioxa-14-azatricyclo[9.5.1.0¹⁴,¹⁷]heptadec-11-ene-3,8-dione

C18H25NO5 (335.1733)


   

Renardin

2,9-DIOXA-14-AZABICYCLO(9.5.1)HEPTADEC-11-ENE-3,8,17-TRIONE, 4-ETHYLIDENE-7-HYDROXY-6,7,14-TRIMETHYL-, (1R,4Z,6R,7R)-

C19H27NO6 (365.1838)


Senkirkine is a macrolide. Senkirkine is a natural product found in Tussilago farfara, Senecio gallicus, and other organisms with data available. See also: Petasites hybridus root (part of); Tussilago farfara flower (part of); Tussilago farfara leaf (part of).

   
   

4-ethylidene-6,7,14-trimethyl-3,8,17-trioxo-2,9-dioxa-14-azabicyclo[9.5.1]heptadec-11-en-7-yl acetate

4-ethylidene-6,7,14-trimethyl-3,8,17-trioxo-2,9-dioxa-14-azabicyclo[9.5.1]heptadec-11-en-7-yl acetate

C21H29NO7 (407.1944)


   

7-(hydroxymethyl)-2,3,5,7a-tetrahydro-1h-pyrrolizin-1-yl 2-methylbut-2-enoate

7-(hydroxymethyl)-2,3,5,7a-tetrahydro-1h-pyrrolizin-1-yl 2-methylbut-2-enoate

C13H19NO3 (237.1365)


   

(1s,3s,3ar,5s,6r,7s,7ar)-1-[(1r)-1-(acetyloxy)ethyl]-3,6-bis({[(2s)-2-methylbutanoyl]oxy})-4-methylidene-7-[(2s)-2-methyloxiran-2-yl]-2-oxo-hexahydro-1h-inden-5-yl (2e)-3-methylpent-2-enoate

(1s,3s,3ar,5s,6r,7s,7ar)-1-[(1r)-1-(acetyloxy)ethyl]-3,6-bis({[(2s)-2-methylbutanoyl]oxy})-4-methylidene-7-[(2s)-2-methyloxiran-2-yl]-2-oxo-hexahydro-1h-inden-5-yl (2e)-3-methylpent-2-enoate

C33H48O10 (604.3247)


   

(4e)-4-ethylidene-7-hydroxy-6,7-dimethyl-2,9-dioxa-14-azatricyclo[9.5.1.0¹⁴,¹⁷]heptadec-11-ene-3,8-dione

(4e)-4-ethylidene-7-hydroxy-6,7-dimethyl-2,9-dioxa-14-azatricyclo[9.5.1.0¹⁴,¹⁷]heptadec-11-ene-3,8-dione

C18H25NO5 (335.1733)


   

7-(hydroxymethyl)-hexahydro-1h-pyrrolizin-1-yl 2-methylbut-2-enoate

7-(hydroxymethyl)-hexahydro-1h-pyrrolizin-1-yl 2-methylbut-2-enoate

C13H21NO3 (239.1521)


   

(1s,4z,6s,7s)-4-ethylidene-6,7,14-trimethyl-3,8,17-trioxo-2,9-dioxa-14-azabicyclo[9.5.1]heptadec-11-en-7-yl acetate

(1s,4z,6s,7s)-4-ethylidene-6,7,14-trimethyl-3,8,17-trioxo-2,9-dioxa-14-azabicyclo[9.5.1]heptadec-11-en-7-yl acetate

C21H29NO7 (407.1944)


   

(1s,3ar,5s,6r,7s,7ar)-1-[(1r)-1-(acetyloxy)ethyl]-6-{[(2s)-2-methylbutanoyl]oxy}-4-methylidene-7-[(2s)-2-methyloxiran-2-yl]-2-oxo-hexahydro-1h-inden-5-yl (2e)-3-methylpent-2-enoate

(1s,3ar,5s,6r,7s,7ar)-1-[(1r)-1-(acetyloxy)ethyl]-6-{[(2s)-2-methylbutanoyl]oxy}-4-methylidene-7-[(2s)-2-methyloxiran-2-yl]-2-oxo-hexahydro-1h-inden-5-yl (2e)-3-methylpent-2-enoate

C28H40O8 (504.2723)


   

4-ethylidene-7-hydroxy-6,7,14-trimethyl-2,9-dioxa-14-azabicyclo[9.5.1]heptadec-11-ene-3,8,17-trione

4-ethylidene-7-hydroxy-6,7,14-trimethyl-2,9-dioxa-14-azabicyclo[9.5.1]heptadec-11-ene-3,8,17-trione

C19H27NO6 (365.1838)


   

(1s,3ar,5s,6r,7s,7ar)-1-[(1r)-1-(acetyloxy)ethyl]-7-isopropyl-6-{[(2s)-2-methylbutanoyl]oxy}-4-methylidene-2-oxo-hexahydro-1h-inden-5-yl (2e)-3-methylpent-2-enoate

(1s,3ar,5s,6r,7s,7ar)-1-[(1r)-1-(acetyloxy)ethyl]-7-isopropyl-6-{[(2s)-2-methylbutanoyl]oxy}-4-methylidene-2-oxo-hexahydro-1h-inden-5-yl (2e)-3-methylpent-2-enoate

C28H42O7 (490.293)


   

(1r,4e,6s,7r,11z)-4-ethylidene-6,7,14-trimethyl-3,8,17-trioxo-2,9-dioxa-14-azabicyclo[9.5.1]heptadec-11-en-7-yl acetate

(1r,4e,6s,7r,11z)-4-ethylidene-6,7,14-trimethyl-3,8,17-trioxo-2,9-dioxa-14-azabicyclo[9.5.1]heptadec-11-en-7-yl acetate

C21H29NO7 (407.1944)


   

(3s,3ar,5s,6r,7s,7ar)-1-ethylidene-3,6-bis({[(2s)-2-methylbutanoyl]oxy})-4-methylidene-7-[(2s)-2-methyloxiran-2-yl]-2-oxo-hexahydroinden-5-yl (2e)-3-methylpent-2-enoate

(3s,3ar,5s,6r,7s,7ar)-1-ethylidene-3,6-bis({[(2s)-2-methylbutanoyl]oxy})-4-methylidene-7-[(2s)-2-methyloxiran-2-yl]-2-oxo-hexahydroinden-5-yl (2e)-3-methylpent-2-enoate

C31H44O8 (544.3036)


   

(1r,7r,7ar)-7-(hydroxymethyl)-hexahydro-1h-pyrrolizin-1-yl (2z)-2-methylbut-2-enoate

(1r,7r,7ar)-7-(hydroxymethyl)-hexahydro-1h-pyrrolizin-1-yl (2z)-2-methylbut-2-enoate

C13H21NO3 (239.1521)


   

(1z,3s,3ar,5s,6r,7s,7ar)-1-ethylidene-3,6-bis({[(2s)-2-methylbutanoyl]oxy})-4-methylidene-7-[(2s)-2-methyloxiran-2-yl]-2-oxo-hexahydroinden-5-yl (2e)-3-methylpent-2-enoate

(1z,3s,3ar,5s,6r,7s,7ar)-1-ethylidene-3,6-bis({[(2s)-2-methylbutanoyl]oxy})-4-methylidene-7-[(2s)-2-methyloxiran-2-yl]-2-oxo-hexahydroinden-5-yl (2e)-3-methylpent-2-enoate

C31H44O8 (544.3036)


   

(1r,4z,6r,7s,11z)-4-ethylidene-6,7,14-trimethyl-3,8,17-trioxo-2,9-dioxa-14-azabicyclo[9.5.1]heptadec-11-en-7-yl acetate

(1r,4z,6r,7s,11z)-4-ethylidene-6,7,14-trimethyl-3,8,17-trioxo-2,9-dioxa-14-azabicyclo[9.5.1]heptadec-11-en-7-yl acetate

C21H29NO7 (407.1944)


   

(1r,4e,6r,7s,11z)-4-ethylidene-6,7,14-trimethyl-3,8,17-trioxo-2,9-dioxa-14-azabicyclo[9.5.1]heptadec-11-en-7-yl acetate

(1r,4e,6r,7s,11z)-4-ethylidene-6,7,14-trimethyl-3,8,17-trioxo-2,9-dioxa-14-azabicyclo[9.5.1]heptadec-11-en-7-yl acetate

C21H29NO7 (407.1944)


   

(1r,4e,6s,7r)-4-ethylidene-6,7,14-trimethyl-3,8,17-trioxo-2,9-dioxa-14-azabicyclo[9.5.1]heptadec-11-en-7-yl acetate

(1r,4e,6s,7r)-4-ethylidene-6,7,14-trimethyl-3,8,17-trioxo-2,9-dioxa-14-azabicyclo[9.5.1]heptadec-11-en-7-yl acetate

C21H29NO7 (407.1944)


   

(1r,4z,6r,7r)-4-ethylidene-7-hydroxy-6,7,14-trimethyl-2,9-dioxa-14-azabicyclo[9.5.1]heptadec-11-ene-3,8,17-trione

(1r,4z,6r,7r)-4-ethylidene-7-hydroxy-6,7,14-trimethyl-2,9-dioxa-14-azabicyclo[9.5.1]heptadec-11-ene-3,8,17-trione

C19H27NO6 (365.1838)


   

(1s,4z,6s,7s,11z)-4-ethylidene-6,7,14-trimethyl-3,8,17-trioxo-2,9-dioxa-14-azabicyclo[9.5.1]heptadec-11-en-7-yl acetate

(1s,4z,6s,7s,11z)-4-ethylidene-6,7,14-trimethyl-3,8,17-trioxo-2,9-dioxa-14-azabicyclo[9.5.1]heptadec-11-en-7-yl acetate

C21H29NO7 (407.1944)