NCBI Taxonomy: 149688

Ormosia amazonica (ncbi_taxid: 149688)

found 40 associated metabolites at species taxonomy rank level.

Ancestor: Ormosia

Child Taxonomies: none taxonomy data.

Sparteine

7,14-METHANO-2H,6H-DIPYRIDO(1,2-A:1,2-E)(1,5)DIAZOCINE, DODECAHYDRO-, (7S-(7.ALPHA.,7A.BETA.,14.ALPHA.,14A.BETA.))-

C15H26N2 (234.2095876)


Sparteine is a quinolizidine alkaloid and a quinolizidine alkaloid fundamental parent. Sparteine is a plant alkaloid derived from Cytisus scoparius and Lupinus mutabilis which may chelate calcium and magnesium. It is a sodium channel blocker, so it falls in the category of class 1a antiarrhythmic agents. Sparteine is not currently FDA-approved for human use, and its salt, sparteine sulfate, is one of the products that have been withdrawn or removed from the market for reasons of safety or effectiveness. Sparteine is a natural product found in Ormosia coarctata, Thermopsis chinensis, and other organisms with data available. A quinolizidine alkaloid isolated from several FABACEAE including LUPINUS; SPARTIUM; and CYTISUS. It has been used as an oxytocic and an anti-arrhythmia agent. It has also been of interest as an indicator of CYP2D6 genotype. See also: Cytisus scoparius flowering top (part of). C - Cardiovascular system > C01 - Cardiac therapy > C01B - Antiarrhythmics, class i and iii > C01BA - Antiarrhythmics, class ia C78274 - Agent Affecting Cardiovascular System > C47793 - Antiarrhythmic Agent D002317 - Cardiovascular Agents > D000889 - Anti-Arrhythmia Agents D012102 - Reproductive Control Agents > D010120 - Oxytocics Annotation level-1 CONFIDENCE Reference Standard (Level 1); INTERNAL_ID 53 CONFIDENCE Reference Standard (Level 1); INTERNAL_ID 39 CONFIDENCE Reference Standard (Level 1); INTERNAL_ID 32 INTERNAL_ID 24; CONFIDENCE Reference Standard (Level 1) CONFIDENCE Reference Standard (Level 1); INTERNAL_ID 24 CONFIDENCE Reference Standard (Level 1); INTERNAL_ID 17 CONFIDENCE Reference Standard (Level 1); INTERNAL_ID 9 CONFIDENCE Reference Standard (Level 1); INTERNAL_ID 2 relative retention time with respect to 9-anthracene Carboxylic Acid is 0.395 beta-Isosparteine is a natural product found in Ulex airensis, Ulex densus, and other organisms with data available. A quinolizidine alkaloid isolated from several FABACEAE including LUPINUS; SPARTIUM; and CYTISUS. It has been used as an oxytocic and an anti-arrhythmia agent. It has also been of interest as an indicator of CYP2D6 genotype. (+)-Sparteine is a natural product found in Baptisia australis, Dermatophyllum secundiflorum, and other organisms with data available. A quinolizidine alkaloid isolated from several FABACEAE including LUPINUS; SPARTIUM; and CYTISUS. It has been used as an oxytocic and an anti-arrhythmia agent. It has also been of interest as an indicator of CYP2D6 genotype. (-)-Sparteine is a natural alkaloid isolated from beans. (-)-Sparteine is a natural alkaloid isolated from beans. (+)-Sparteine is a natural alkaloid acting as a ganglionic blocking agent. (+)-Sparteine competitively blocks nicotinic ACh receptor in the neurons. (+)-Sparteine is a natural alkaloid acting as a ganglionic blocking agent. (+)-Sparteine competitively blocks nicotinic ACh receptor in the neurons. (+)-Sparteine is a natural alkaloid acting as a ganglionic blocking agent. (+)-Sparteine competitively blocks nicotinic ACh receptor in the neurons.

   

13-hydroxylupanine

(+)-13α-Hydroxylupanine

C15H24N2O2 (264.18376839999996)


   
   

17-Oxosparteine

7,14-Methano-2H,6H-dipyrido[1,2-a:1,2-E][1,5]diazocin-6-one, dodecahydro-, [7R-(7alpha,7aalpha,14alpha,14abeta)]-

C15H24N2O (248.18885339999997)


   

Ormosanine

Ormosanine

C20H35N3 (317.28308300000003)


Annotation level-1

   

Pachycarpine

(+)-Sparteine

C15H26N2 (234.2095876)


C - Cardiovascular system > C01 - Cardiac therapy > C01B - Antiarrhythmics, class i and iii > C01BA - Antiarrhythmics, class ia D002317 - Cardiovascular Agents > D000889 - Anti-Arrhythmia Agents D012102 - Reproductive Control Agents > D010120 - Oxytocics CONFIDENCE Reference Standard (Level 1); INTERNAL_ID 3 (-)-Sparteine is a natural alkaloid isolated from beans. (-)-Sparteine is a natural alkaloid isolated from beans. (+)-Sparteine is a natural alkaloid acting as a ganglionic blocking agent. (+)-Sparteine competitively blocks nicotinic ACh receptor in the neurons. (+)-Sparteine is a natural alkaloid acting as a ganglionic blocking agent. (+)-Sparteine competitively blocks nicotinic ACh receptor in the neurons. (+)-Sparteine is a natural alkaloid acting as a ganglionic blocking agent. (+)-Sparteine competitively blocks nicotinic ACh receptor in the neurons.

   

(1r,11s,13r,14r)-7,19,23-triazahexacyclo[9.9.1.1¹,¹³.1²,⁶.0⁷,²¹.0¹⁴,¹⁹]tricosane

(1r,11s,13r,14r)-7,19,23-triazahexacyclo[9.9.1.1¹,¹³.1²,⁶.0⁷,²¹.0¹⁴,¹⁹]tricosane

C20H33N3 (315.26743380000005)


   

1-(piperidin-2-yl)-3,15-diazatetracyclo[7.7.1.0²,⁷.0¹⁰,¹⁵]heptadecane

1-(piperidin-2-yl)-3,15-diazatetracyclo[7.7.1.0²,⁷.0¹⁰,¹⁵]heptadecane

C20H35N3 (317.28308300000003)


   

(1r,2s,6s,11r,13s,14s,21s)-7,19,23-triazahexacyclo[9.9.1.1¹,¹³.1²,⁶.0⁷,²¹.0¹⁴,¹⁹]tricosane

(1r,2s,6s,11r,13s,14s,21s)-7,19,23-triazahexacyclo[9.9.1.1¹,¹³.1²,⁶.0⁷,²¹.0¹⁴,¹⁹]tricosane

C20H33N3 (315.26743380000005)


   
   

(7r)-1-[(2s)-piperidin-2-yl]-3,15-diazatetracyclo[7.7.1.0²,⁷.0¹⁰,¹⁵]heptadecane

(7r)-1-[(2s)-piperidin-2-yl]-3,15-diazatetracyclo[7.7.1.0²,⁷.0¹⁰,¹⁵]heptadecane

C20H35N3 (317.28308300000003)


   

(1s,2s,7s,9r,10r)-1-[(2r)-piperidin-2-yl]-3,15-diazatetracyclo[7.7.1.0²,⁷.0¹⁰,¹⁵]heptadecane

(1s,2s,7s,9r,10r)-1-[(2r)-piperidin-2-yl]-3,15-diazatetracyclo[7.7.1.0²,⁷.0¹⁰,¹⁵]heptadecane

C20H35N3 (317.28308300000003)


   

7,19,23-triazahexacyclo[9.9.1.1¹,¹³.1²,⁶.0⁷,²¹.0¹⁴,¹⁹]tricosane

7,19,23-triazahexacyclo[9.9.1.1¹,¹³.1²,⁶.0⁷,²¹.0¹⁴,¹⁹]tricosane

C20H33N3 (315.26743380000005)


   

(1r,2r,9s,10r)-7,15-diazatetracyclo[7.7.1.0²,⁷.0¹⁰,¹⁵]heptadecan-6-one

(1r,2r,9s,10r)-7,15-diazatetracyclo[7.7.1.0²,⁷.0¹⁰,¹⁵]heptadecan-6-one

C15H24N2O (248.18885339999997)


   

(2r,10s)-7,15-diazatetracyclo[7.7.1.0²,⁷.0¹⁰,¹⁵]heptadecane

(2r,10s)-7,15-diazatetracyclo[7.7.1.0²,⁷.0¹⁰,¹⁵]heptadecane

C15H26N2 (234.2095876)


   
   

(1r,2s,6r,11s,13r,14r,21r)-7,19,23-triazahexacyclo[9.9.1.1¹,¹³.1²,⁶.0⁷,²¹.0¹⁴,¹⁹]tricosane

(1r,2s,6r,11s,13r,14r,21r)-7,19,23-triazahexacyclo[9.9.1.1¹,¹³.1²,⁶.0⁷,²¹.0¹⁴,¹⁹]tricosane

C20H33N3 (315.26743380000005)