NCBI Taxonomy: 141960
Siparuna pauciflora (ncbi_taxid: 141960)
found 63 associated metabolites at species taxonomy rank level.
Ancestor: Siparuna
Child Taxonomies: none taxonomy data.
(S)-Boldine
C19H21NO4 (327.14705060000006)
Boldine is an aporphine alkaloid. Boldine is a natural product found in Lindera umbellata, Damburneya salicifolia, and other organisms with data available. See also: Peumus boldus leaf (part of). (S)-Boldine is found in sweet bay. (S)-Boldine is an alkaloid from Sassafras and the leaves of Peumus boldus (boldo). (S)-Boldine is a flavouring ingredient. Alkaloid from Sassafras and the leaves of Peumus boldus (boldo). Flavouring ingredient. (S)-Boldine is found in sweet bay. D018373 - Peripheral Nervous System Agents > D009465 - Neuromuscular Agents > D009466 - Neuromuscular Blocking Agents D018373 - Peripheral Nervous System Agents > D018689 - Sensory System Agents D002491 - Central Nervous System Agents > D000700 - Analgesics D020011 - Protective Agents > D000975 - Antioxidants D000893 - Anti-Inflammatory Agents D018501 - Antirheumatic Agents Boldine is an aporphine isoquinoline alkaloid extracted from the root of Litsea cubeba and also possesses these properties, including antioxidant, anti-inflammatory and cytoprotective effects. Boldine suppresses osteoclastogenesis, improves bone destruction by down-regulating the OPG/RANKL/RANK signal pathway and may be a potential therapeutic agent for rheumatoid arthritis[1]. Boldine is an aporphine isoquinoline alkaloid extracted from the root of Litsea cubeba and also possesses these properties, including antioxidant, anti-inflammatory and cytoprotective effects. Boldine suppresses osteoclastogenesis, improves bone destruction by down-regulating the OPG/RANKL/RANK signal pathway and may be a potential therapeutic agent for rheumatoid arthritis[1].
Laurolitsine
Laurolistine is an aporphine alkaloid that is noraporphine substituted by hydroxy groups at positions 2 and 9 and methoxy groups at positions 1 and 10. Isolated from Litsea glutinosa and Lindera chunii, exhibits inhibitory activity against HIV-1 integrase. It has a role as a metabolite and a HIV-1 integrase inhibitor. It is a member of phenols, an aromatic ether and an aporphine alkaloid. It is functionally related to an aporphine. Laurolitsine is a natural product found in Damburneya salicifolia, Neolitsea sericea, and other organisms with data available. Laurolitsine is an alkaloid from Sassafras and the leaves of Peumus boldus (boldo). Laurolitsine is a flavouring ingredient. Alkaloid from Sassafras and the leaves of Peumus boldus (boldo). Flavouring ingredient
Nantenine
C20H21NO4 (339.14705060000006)
A natural product found in Corydalis cava and Nandina domestica. Annotation level-1
Laurotetanine
C19H21NO4 (327.14705060000006)
Laurotetanine is found in cherimoya. Laurotetanine is an alkaloid from the leaves of Peumus boldus (boldo Alkaloid from the leaves of Peumus boldus (boldo). Laurotetanine is found in cherimoya.
Boldine
C19H21NO4 (327.14705060000006)
Boldine is an aporphine alkaloid. Boldine is a natural product found in Lindera umbellata, Damburneya salicifolia, and other organisms with data available. See also: Peumus boldus leaf (part of). D018373 - Peripheral Nervous System Agents > D009465 - Neuromuscular Agents > D009466 - Neuromuscular Blocking Agents D018373 - Peripheral Nervous System Agents > D018689 - Sensory System Agents D002491 - Central Nervous System Agents > D000700 - Analgesics D020011 - Protective Agents > D000975 - Antioxidants D000893 - Anti-Inflammatory Agents D018501 - Antirheumatic Agents (s)-boldine is a member of the class of compounds known as aporphines. Aporphines are quinoline alkaloids containing the dibenzo[de,g]quinoline ring system or a dehydrogenated derivative thereof (s)-boldine is practically insoluble (in water) and a very weakly acidic compound (based on its pKa). (s)-boldine can be found in sweet bay, which makes (s)-boldine a potential biomarker for the consumption of this food product. Origin: Plant; Formula(Parent): C19H21NO4; Bottle Name:Boldine hydrochloride; PRIME Parent Name:Boldine; PRIME in-house No.:V0322; SubCategory_DNP: Isoquinoline alkaloids, Benzylisoquinoline alkaloids Annotation level-1 relative retention time with respect to 9-anthracene Carboxylic Acid is 0.487 relative retention time with respect to 9-anthracene Carboxylic Acid is 0.480 relative retention time with respect to 9-anthracene Carboxylic Acid is 0.482 IPB_RECORD: 841; CONFIDENCE confident structure Boldine is an aporphine isoquinoline alkaloid extracted from the root of Litsea cubeba and also possesses these properties, including antioxidant, anti-inflammatory and cytoprotective effects. Boldine suppresses osteoclastogenesis, improves bone destruction by down-regulating the OPG/RANKL/RANK signal pathway and may be a potential therapeutic agent for rheumatoid arthritis[1]. Boldine is an aporphine isoquinoline alkaloid extracted from the root of Litsea cubeba and also possesses these properties, including antioxidant, anti-inflammatory and cytoprotective effects. Boldine suppresses osteoclastogenesis, improves bone destruction by down-regulating the OPG/RANKL/RANK signal pathway and may be a potential therapeutic agent for rheumatoid arthritis[1].
6a&alpha
C19H21NO4 (327.14705060000006)
Norboldine
Norboldine
Laurolistine is an aporphine alkaloid that is noraporphine substituted by hydroxy groups at positions 2 and 9 and methoxy groups at positions 1 and 10. Isolated from Litsea glutinosa and Lindera chunii, exhibits inhibitory activity against HIV-1 integrase. It has a role as a metabolite and a HIV-1 integrase inhibitor. It is a member of phenols, an aromatic ether and an aporphine alkaloid. It is functionally related to an aporphine. Laurolitsine is a natural product found in Damburneya salicifolia, Neolitsea sericea, and other organisms with data available. An aporphine alkaloid that is noraporphine substituted by hydroxy groups at positions 2 and 9 and methoxy groups at positions 1 and 10. Isolated from Litsea glutinosa and Lindera chunii, exhibits inhibitory activity against HIV-1 integrase.
1,2,10-Trimethoxy-5,6,6a,7-tetrahydro-4h-dibenzo[de,g]quinolin-9-ol
C19H21NO4 (327.14705060000006)
(2s)-2-[(4s)-4-[(1r,2r,5s)-2-[(acetyloxy)methyl]-1-methyl-6-oxabicyclo[3.1.0]hexan-2-yl]-3-oxocyclopent-1-en-1-yl]-2-hydroxypropyl acetate
(2s)-2-[(4r,5s)-5-[3-(acetyloxy)prop-1-en-2-yl]-4-ethenyl-4-methyl-3-oxocyclohex-1-en-1-yl]-2-hydroxypropyl acetate
(1r,3s,3'r,6e,10r)-10-[(acetyloxy)methyl]-3',6-dimethyl-5-oxo-11-oxaspiro[bicyclo[8.1.0]undecane-3,2'-oxiran]-6-en-3'-ylmethyl acetate
4,16-dimethoxy-10-methyl-10-azatetracyclo[7.7.1.0²,⁷.0¹³,¹⁷]heptadeca-1(16),2(7),3,5,13(17),14-hexaene-5,15-diol
C19H21NO4 (327.14705060000006)
10-[(acetyloxy)methyl]-3',6-dimethyl-5-oxo-11-oxaspiro[bicyclo[8.1.0]undecane-3,2'-oxiran]-6-en-3'-ylmethyl acetate
(2r)-2-[(4r,5s)-5-[3-(acetyloxy)prop-1-en-2-yl]-4-ethenyl-4-methyl-3-oxocyclohex-1-en-1-yl]-2-hydroxypropyl acetate
(9s)-4,16-dimethoxy-10-methyl-10-azatetracyclo[7.7.1.0²,⁷.0¹³,¹⁷]heptadeca-1(16),2(7),3,5,13(17),14-hexaene-5,15-diol
C19H21NO4 (327.14705060000006)
(12s,13s)-3,5-dioxa-11-azapentacyclo[10.7.1.0²,⁶.0⁸,²⁰.0¹⁴,¹⁹]icosa-1,6,8(20),14,16,18-hexaen-13-ol
4,15,16-trimethoxy-10-azatetracyclo[7.7.1.0²,⁷.0¹³,¹⁷]heptadeca-1(17),2(7),3,5,13,15-hexaen-5-ol
C19H21NO4 (327.14705060000006)
4,16-dimethoxy-10-azatetracyclo[7.7.1.0²,⁷.0¹³,¹⁷]heptadeca-1(17),2(7),3,5,13,15-hexaene-5,15-diol
4,15,16-trimethoxy-10-methyl-10-azatetracyclo[7.7.1.0²,⁷.0¹³,¹⁷]heptadeca-1(16),2(7),3,5,13(17),14-hexaen-5-ol
C20H23NO4 (341.16269980000004)
2-(4-{2-[(acetyloxy)methyl]-1-methyl-6-oxabicyclo[3.1.0]hexan-2-yl}-3-oxocyclopent-1-en-1-yl)-2-hydroxypropyl acetate
(1s,3s,3'r,6z,10s)-10-[(acetyloxy)methyl]-3',6-dimethyl-5-oxo-11-oxaspiro[bicyclo[8.1.0]undecane-3,2'-oxiran]-6-en-3'-ylmethyl acetate
2-{5-[3-(acetyloxy)prop-1-en-2-yl]-4-ethenyl-4-methyl-3-oxocyclohex-1-en-1-yl}-2-hydroxypropyl acetate
(2r)-2-[(4s)-4-[(1r,2r,5s)-2-[(acetyloxy)methyl]-1-methyl-6-oxabicyclo[3.1.0]hexan-2-yl]-3-oxocyclopent-1-en-1-yl]-2-hydroxypropyl acetate
(9s)-4,15,16-trimethoxy-10-methyl-10-azatetracyclo[7.7.1.0²,⁷.0¹³,¹⁷]heptadeca-1(16),2(7),3,5,13(17),14-hexaen-5-ol
C20H23NO4 (341.16269980000004)