NCBI Taxonomy: 1273271
Triphoridae (ncbi_taxid: 1273271)
found 56 associated metabolites at family taxonomy rank level.
Ancestor: Triphoroidea
Child Taxonomies: Viriola, Triphora, Iniforis, Lucilina, Mesophora, Litharium, Opimaphora, Coriophora, Subulophora, Viriolopsis, Marshallora, Nototriphora, unclassified Triphoridae
Griseofulvin
Griseofulvin is only found in individuals that have used or taken this drug. It is an antifungal antibiotic. Griseofulvin may be given by mouth in the treatment of tinea infections. [PubChem]Griseofulvin is fungistatic, however the exact mechanism by which it inhibits the growth of dermatophytes is not clear. It is thought to inhibit fungal cell mitosis and nuclear acid synthesis. It also binds to and interferes with the function of spindle and cytoplasmic microtubules by binding to alpha and beta tubulin. It binds to keratin in human cells, then once it reaches the fungal site of action, it binds to fungal microtubes thus altering the fungal process of mitosis. D - Dermatologicals > D01 - Antifungals for dermatological use > D01B - Antifungals for systemic use > D01BA - Antifungals for systemic use D - Dermatologicals > D01 - Antifungals for dermatological use > D01A - Antifungals for topical use > D01AA - Antibiotics D000890 - Anti-Infective Agents > D000935 - Antifungal Agents C254 - Anti-Infective Agent > C514 - Antifungal Agent Griseofulvin(Gris-PEG; Grifulvin) is a spirocyclic fungal natural product used in treatment of fungal dermatophytes; Antifungal drug.
4,5-dibromo-N-(methoxymethyl)-1H-pyrrole-2-carboxamide
Griseofulvin
An oxaspiro compound produced by Penicillium griseofulvum. It is used by mouth as an antifungal drug for infections involving the scalp, hair, nails and skin that do not respond to topical treatment. D - Dermatologicals > D01 - Antifungals for dermatological use > D01B - Antifungals for systemic use > D01BA - Antifungals for systemic use D - Dermatologicals > D01 - Antifungals for dermatological use > D01A - Antifungals for topical use > D01AA - Antibiotics D000890 - Anti-Infective Agents > D000935 - Antifungal Agents C254 - Anti-Infective Agent > C514 - Antifungal Agent CONFIDENCE Reference Standard (Level 1) relative retention time with respect to 9-anthracene Carboxylic Acid is 1.075 Griseofulvin(Gris-PEG; Grifulvin) is a spirocyclic fungal natural product used in treatment of fungal dermatophytes; Antifungal drug.
5-[(4z)-3-bromo-8-hydroxy-1h,5h,6h-pyrrolo[2,3-c]azepin-4-ylidene]-2-imino-1h-imidazol-4-ol
[(1s,2r,5s,6s,9s,10s,13r,14r)-13-[(2r,5r)-5-ethyl-6-methylheptan-2-yl]-2,14-dimethyltetracyclo[7.7.0.0²,⁶.0¹⁰,¹⁴]hexadecan-5-yl]methyl acetate
1-[25-(3,3-dimethyloxiran-2-yl)-15-methyl-1,3,13,15-tetraazaheptacyclo[18.4.1.0²,⁶.0⁶,²².0⁷,¹².0¹⁴,²².0¹⁶,²¹]pentacosa-7,9,11,16,18,20-hexaen-3-yl]hexa-2,4-dien-1-one
(1'r,4r,5r,5's,14'r,15's,16'r,18's)-15'-(aminomethyl)-7',8'-dibromo-16'-chloro-5-hydroxy-2,3'-diimino-2',4',6',12'-tetraazaspiro[imidazolidine-4,17'-pentacyclo[10.6.0.0¹,⁵.0⁶,¹⁰.0¹⁴,¹⁸]octadecane]-7',9'-dien-11'-one
(4s,6s)-6-[(4-bromo-1h-pyrrole-2-carbonyloxy)methyl]-1,6-dimethyl-4,5-dihydropyrimidine-4-carboxylic acid
C13H16BrN3O4 (357.03241160000005)
2-{[(5z)-5-{3-[(4-bromo-1h-pyrrol-2-yl)formamido]propylidene}-2-iminoimidazolidin-4-ylidene]amino}ethanesulfonic acid
C13H17BrN6O4S (432.02153020000003)
4-bromo-n-(methoxymethyl)-1h-pyrrole-2-carboxamide
15'-(aminomethyl)-7',8'-dibromo-16'-chloro-5-hydroxy-2,3'-diimino-2',4',6',12'-tetraazaspiro[imidazolidine-4,17'-pentacyclo[10.6.0.0¹,⁵.0⁶,¹⁰.0¹⁴,¹⁸]octadecane]-7',9'-dien-11'-one
(2e,4e)-1-[(2r,6s,14s,22s,25r)-25-[(2s)-3,3-dimethyloxiran-2-yl]-1,3,13,15-tetraazaheptacyclo[18.4.1.0²,⁶.0⁶,²².0⁷,¹².0¹⁴,²².0¹⁶,²¹]pentacosa-7,9,11,16,18,20-hexaen-3-yl]hexa-2,4-dien-1-one
(4s,6s)-6-[(4-bromo-1h-pyrrole-2-carbonyloxy)methyl]-6-methyl-4,5-dihydro-1h-pyrimidine-4-carboxylic acid
C12H14BrN3O4 (343.01676240000006)
4,5-dibromo-n-{7'-bromo-16'-chloro-5-hydroxy-2,3'-diimino-11'-oxo-2',4',9',12'-tetraazaspiro[imidazolidine-4,17'-pentacyclo[10.6.0.0¹,⁵.0⁶,¹⁰.0¹⁴,¹⁸]octadecane]-6'(10'),7'-dien-15'-ylmethyl}-1h-pyrrole-2-carboxamide
C22H22Br3ClN10O3 (745.9114872)
7-bromo-4-hydroxy-2h,3h,4h-pyrrolo[1,2-a]pyrazin-1-one
C7H7BrN2O2 (229.96908620000002)
4-bromo-n-[3-(5-hydroxy-2-imino-3h-imidazol-4-ylidene)-2-methoxypropyl]-1h-pyrrole-2-carboxamide
(2r,6s,14s,22s,25r)-25-[(2s)-3,3-dimethyloxiran-2-yl]-3-[(2e,4e)-hexa-2,4-dienoyl]-1,3,13,15-tetraazaheptacyclo[18.4.1.0²,⁶.0⁶,²².0⁷,¹².0¹⁴,²².0¹⁶,²¹]pentacosa-7,9,11,16,18,20-hexaene-15-carbaldehyde
4-bromo-n-[(2r)-2-hydroxy-3-[(4z)-5-hydroxy-2-imino-3h-imidazol-4-ylidene]propyl]-1h-pyrrole-2-carboxamide
5-{2,3-dibromo-8-oxo-1h,5h,6h,7h-pyrrolo[2,3-c]azepin-4-ylidene}-2-iminoimidazolidin-4-one
[(1s,2r,5s,6s,9s,10s,13r,14r)-2,14-dimethyl-13-[(2r)-6-methylheptan-2-yl]tetracyclo[7.7.0.0²,⁶.0¹⁰,¹⁴]hexadecan-5-yl]methyl acetate
(1'r,4r,5r,5's,6's,14'r,15's,16'r,18's)-15'-(aminomethyl)-7',8'-dibromo-16'-chloro-5-hydroxy-2,3'-diimino-2',4',9',12'-tetraazaspiro[imidazolidine-4,17'-pentacyclo[10.6.0.0¹,⁵.0⁶,¹⁰.0¹⁴,¹⁸]octadecane]-7',9'-dien-11'-one
4-bromo-n-[3-(2,5-dihydroxyimidazol-4-ylidene)propyl]-1h-pyrrole-2-carboxamide
2-[(5-{3-[(4-bromo-1h-pyrrol-2-yl)formamido]propylidene}-2-iminoimidazolidin-4-ylidene)amino]ethanesulfonic acid
C13H17BrN6O4S (432.02153020000003)
4,5-dibromo-n-[(1'r,4r,5s,5's,14's,15's,16's,18's)-7'-bromo-16'-chloro-5-hydroxy-2,3'-diimino-11'-oxo-2',4',9',12'-tetraazaspiro[imidazolidine-4,17'-pentacyclo[10.6.0.0¹,⁵.0⁶,¹⁰.0¹⁴,¹⁸]octadecane]-6'(10'),7'-dien-15'-ylmethyl]-1h-pyrrole-2-carboxamide
C22H22Br3ClN10O3 (745.9114872)
2-{[(5z)-5-{3-[(4,5-dibromo-1h-pyrrol-2-yl)formamido]propylidene}-2-iminoimidazolidin-4-ylidene]amino}ethanesulfonic acid
C13H16Br2N6O4S (509.93204160000005)
4,5-dibromo-n-[(1'r,4r,5s,5's,14's,15's,16's,18's)-7',8'-dibromo-16'-chloro-5-hydroxy-2,3'-diimino-11'-oxo-2',4',9',12'-tetraazaspiro[imidazolidine-4,17'-pentacyclo[10.6.0.0¹,⁵.0⁶,¹⁰.0¹⁴,¹⁸]octadecane]-6'(10'),7'-dien-15'-ylmethyl]-1h-pyrrole-2-carboxamide
C22H21Br4ClN10O3 (823.8219985999999)
4,5-dibromo-n-{7',8'-dibromo-16'-chloro-5-hydroxy-2,3'-diimino-11'-oxo-2',4',9',12'-tetraazaspiro[imidazolidine-4,17'-pentacyclo[10.6.0.0¹,⁵.0⁶,¹⁰.0¹⁴,¹⁸]octadecane]-6'(10'),7'-dien-15'-ylmethyl}-1h-pyrrole-2-carboxamide
C22H21Br4ClN10O3 (823.8219985999999)
2',4,6-trimethoxy-6'-methylspiro[1-benzofuran-2,1'-cyclohexan]-2'-ene-3,4'-dione
4-bromo-n-[(2e)-3-(2-imino-1,3-dihydroimidazol-4-yl)prop-2-en-1-yl]-1h-pyrrole-2-carboxamide
2-[(5-{3-[(4,5-dibromo-1h-pyrrol-2-yl)formamido]propylidene}-2-iminoimidazolidin-4-ylidene)amino]ethanesulfonic acid
C13H16Br2N6O4S (509.93204160000005)
4-bromo-n-[3-(2-imino-1,3-dihydroimidazol-4-yl)prop-2-en-1-yl]-1h-pyrrole-2-carboxamide
[2,14-dimethyl-13-(6-methylheptan-2-yl)tetracyclo[7.7.0.0²,⁶.0¹⁰,¹⁴]hexadecan-5-yl]methyl acetate
[13-(5,6-dimethylheptan-2-yl)-2,14-dimethyltetracyclo[7.7.0.0²,⁶.0¹⁰,¹⁴]hexadecan-5-yl]methyl acetate
2-bromo-1h,5h,6h,7h-pyrrolo[2,3-c]azepine-4,8-dione
C8H7BrN2O2 (241.96908620000002)
4-bromo-n-[(2r)-3-[(4z)-5-hydroxy-2-imino-3h-imidazol-4-ylidene]-2-methoxypropyl]-1h-pyrrole-2-carboxamide
4-bromo-n-[(2r)-3-[(4z)-2,5-dihydroxyimidazol-4-ylidene]-2-hydroxypropyl]-1h-pyrrole-2-carboxamide
15'-(aminomethyl)-7',8'-dibromo-16'-chloro-5-hydroxy-2,3'-diimino-2',4',9',12'-tetraazaspiro[imidazolidine-4,17'-pentacyclo[10.6.0.0¹,⁵.0⁶,¹⁰.0¹⁴,¹⁸]octadecane]-7',9'-dien-11'-one
(2e,4e)-1-[(2r,6s,14s,22s,25r)-25-[(2s)-3,3-dimethyloxiran-2-yl]-15-methyl-1,3,13,15-tetraazaheptacyclo[18.4.1.0²,⁶.0⁶,²².0⁷,¹².0¹⁴,²².0¹⁶,²¹]pentacosa-7,9,11,16,18,20-hexaen-3-yl]hexa-2,4-dien-1-one
[(1s,2r,5s,6s,9s,10s,13r,14r)-13-[(2r,5r)-5,6-dimethylheptan-2-yl]-2,14-dimethyltetracyclo[7.7.0.0²,⁶.0¹⁰,¹⁴]hexadecan-5-yl]methyl acetate
5-{3-bromo-8-oxo-1h,5h,6h,7h-pyrrolo[2,3-c]azepin-4-ylidene}-2-iminoimidazolidin-4-one
14-(1h-imidazol-4-ylmethylidene)-2,11-dimethoxy-9-(2-methylbut-3-en-2-yl)-2,13,16-triazatetracyclo[7.7.0.0¹,¹³.0³,⁸]hexadeca-3,5,7,10-tetraene-12,15-dione
[13-(5-ethyl-6-methylheptan-2-yl)-2,14-dimethyltetracyclo[7.7.0.0²,⁶.0¹⁰,¹⁴]hexadecan-5-yl]methyl acetate
6-[(4-bromo-1h-pyrrole-2-carbonyloxy)methyl]-1,6-dimethyl-4,5-dihydropyrimidine-4-carboxylic acid
C13H16BrN3O4 (357.03241160000005)
25-(3,3-dimethyloxiran-2-yl)-3-(hexa-2,4-dienoyl)-1,3,13,15-tetraazaheptacyclo[18.4.1.0²,⁶.0⁶,²².0⁷,¹².0¹⁴,²².0¹⁶,²¹]pentacosa-7,9,11,16,18,20-hexaene-15-carbaldehyde
1-[25-(3,3-dimethyloxiran-2-yl)-1,3,13,15-tetraazaheptacyclo[18.4.1.0²,⁶.0⁶,²².0⁷,¹².0¹⁴,²².0¹⁶,²¹]pentacosa-7,9,11,16,18,20-hexaen-3-yl]hexa-2,4-dien-1-one
(4s)-7-bromo-4-hydroxy-2h,3h,4h-pyrrolo[1,2-a]pyrazin-1-one
C7H7BrN2O2 (229.96908620000002)
4-bromo-n-{3-[(4z)-2,5-dihydroxyimidazol-4-ylidene]propyl}-1h-pyrrole-2-carboxamide
(4s,6r)-6-[(4-bromo-1h-pyrrole-2-carbonyloxy)methyl]-6-methyl-4,5-dihydro-1h-pyrimidine-4-carboxylic acid
C12H14BrN3O4 (343.01676240000006)