Gene Association: EVC2

UniProt Search: EVC2 (PROTEIN_CODING)
Function Description: EvC ciliary complex subunit 2

found 5 associated metabolites with current gene based on the text mining result from the pubmed database.

Tetrachlorosalicylanilide

2-Hydroxy-3,4,5,6-tetrachlorobenzanilide

CONFIDENCE standard compound; INTERNAL_ID 2369 D004791 - Enzyme Inhibitors CONFIDENCE Reference Standard (Level 1); INTERNAL_ID 8640 CONFIDENCE Reference Standard (Level 1); INTERNAL_ID 8243

Phosphoramide mustard

amino[bis(2-chloroethyl)amino]phosphinic acid

C4H11Cl2N2O2P (219.9935)

Phosphoramide mustard is a metabolite of cyclophosphamide. Cyclophosphamide (trade names Endoxan, Cytoxan, Neosar, Procytox, Revimmune), also known as cytophosphane, is a nitrogen mustard alkylating agent, from the oxazophorines group. An alkylating agent adds an alkyl group (CnH2n+1) to DNA. It attaches the alkyl group to the guanine base of DNA, at the number 7 nitrogen atom of the imidazole ring. It is used to treat various types of cancer and some autoimmune disorders. (Wikipedia) D000970 - Antineoplastic Agents > D018906 - Antineoplastic Agents, Alkylating > D009588 - Nitrogen Mustard Compounds D000970 - Antineoplastic Agents > D018906 - Antineoplastic Agents, Alkylating > D010752 - Phosphoramide Mustards

3,3',4',5-Tetrachlorosalicylanilide

3,5-dichloro-N-(3,4-dichlorophenyl)-2-hydroxybenzene-1-carboximidic acid

C13H7Cl4NO2 (348.9231)

D004791 - Enzyme Inhibitors

3,3,4,5-Tetrachlorosalicylanilide

C13H7Cl4NO2 (348.9231)

D004791 - Enzyme Inhibitors

Phosphoramide mustard

C4H11Cl2N2O2P (219.9935)

D000970 - Antineoplastic Agents > D018906 - Antineoplastic Agents, Alkylating > D009588 - Nitrogen Mustard Compounds D000970 - Antineoplastic Agents > D018906 - Antineoplastic Agents, Alkylating > D010752 - Phosphoramide Mustards