Chemical Formula: C9H15N5O4

Chemical Formula C9H15N5O4

Found 10 metabolite its formula value is C9H15N5O4

4a-Hydroxytetrahydrobiopterin

(4aS,6R)-2-amino-6-[(1R,2S)-1,2-dihydroxypropyl]-4a-hydroxy-4,4a,5,6,7,8-hexahydropteridin-4-one

C9H15N5O4 (257.11239900000004)


Tetrahydrobiopterin (BH4) is essential for catalyzing the conversion of phenylalanine into tyrosine by phenylalanine hydroxylase. During this physiological reaction, the oxidation of BH4 creates 4a-hydroxytetrahydropterin (CAS: 70110-58-6) intermediates and hydrogen peroxide is formed. The hydrogen peroxide and the hydroxytetrahydropterin can both be derived from alternate breakdown routes of a common precursor, the corresponding 4a-hydroperoxytetrahydropterin (PMID: 8323303). Tetrahydrobiopterin (BH4) is essential to catalyze the conversion of phenylalanine to tyrosine by phenylalanine hydroxylase. During this physiological reaction, the oxidation of BH4 creates 4a-hydroxytetrahydropterin intermediates and hydrogen peroxide is formed. The hydrogen peroxide and the hydroxytetrahydropterin can both derive from alternate routes of breakdown of a common precursor, the corresponding 4a-hydroperoxytetrahydropterin. (PMID 8323303) [HMDB]

   

Tetrahydroneopterin

1-(2-Amino-5,6,7,8-tetrahydro-4-hydroxy-6-pteridinyl)-1,2,3-propanetriol

C9H15N5O4 (257.11239900000004)


Tetrahydroneopterin is a reduced form of neopterin. [HMDB] Tetrahydroneopterin is a reduced form of neopterin.

   

4alpha-hydroxy-tetrahydrobiopterin

2-amino-6-[(1R,2S)-1,2-Dihydroxypropyl]-4a-hydroxy-1,5,6,7-tetrahydropteridin-4-one

C9H15N5O4 (257.11239900000004)


4alpha-hydroxy-tetrahydrobiopterin, also known as 4a-hthb, belongs to biopterins and derivatives class of compounds. Those are coenzymes containing a 2-amino-pteridine-4-one derivative. They are mainly synthesized in several parts of the body, including the pineal gland. 4alpha-hydroxy-tetrahydrobiopterin is slightly soluble (in water) and a very weakly acidic compound (based on its pKa). 4alpha-hydroxy-tetrahydrobiopterin can be found in a number of food items such as garden cress, japanese pumpkin, tronchuda cabbage, and arctic blackberry, which makes 4alpha-hydroxy-tetrahydrobiopterin a potential biomarker for the consumption of these food products. In humans, 4alpha-hydroxy-tetrahydrobiopterin is involved in few metabolic pathways, which include disulfiram action pathway, phenylalanine and tyrosine metabolism, tryptophan metabolism, and tyrosine metabolism. 4alpha-hydroxy-tetrahydrobiopterin is also involved in several metabolic disorders, some of which include hawkinsinuria, monoamine oxidase-a deficiency (MAO-A), phenylketonuria, and tyrosinemia type 3 (TYRO3). 4α-hydroxy-tetrahydrobiopterin, also known as 4a-hthb, belongs to biopterins and derivatives class of compounds. Those are coenzymes containing a 2-amino-pteridine-4-one derivative. They are mainly synthesized in several parts of the body, including the pineal gland. 4α-hydroxy-tetrahydrobiopterin is slightly soluble (in water) and a very weakly acidic compound (based on its pKa). 4α-hydroxy-tetrahydrobiopterin can be found in a number of food items such as garden cress, japanese pumpkin, tronchuda cabbage, and arctic blackberry, which makes 4α-hydroxy-tetrahydrobiopterin a potential biomarker for the consumption of these food products. In humans, 4α-hydroxy-tetrahydrobiopterin is involved in few metabolic pathways, which include disulfiram action pathway, phenylalanine and tyrosine metabolism, tryptophan metabolism, and tyrosine metabolism. 4α-hydroxy-tetrahydrobiopterin is also involved in several metabolic disorders, some of which include hawkinsinuria, monoamine oxidase-a deficiency (MAO-A), phenylketonuria, and tyrosinemia type 3 (TYRO3).

   
   

(6R)-L-threo-5,6,7,8-tetrahydroneopterin

(6R)-L-threo-5,6,7,8-tetrahydroneopterin

C9H15N5O4 (257.11239900000004)


   
   
   

4a-Hydroxytetrahydrobiopterin

(6R)-6-(L-Erythro-1,2-dihydroxypropyl)-5,6,7,8-tetrahydro-4a-hydroxypterin

C9H15N5O4 (257.11239900000004)


A tetrahydropterin that is 5,6,7,8-tetrahydrobiopterin carrying an additional hydroxy substituent at the 4a-position. A 4a-hydroxytetrahydrobiopterin which has R configuration at position 6 and in which the dihydroxypropyl substituent has L-erythro configuration.

   

2-Amino-6-(1,2-dihydroxypropyl)-4a-hydroxy-1,5,6,7-tetrahydropteridin-4-one

2-Amino-6-(1,2-dihydroxypropyl)-4a-hydroxy-1,5,6,7-tetrahydropteridin-4-one

C9H15N5O4 (257.11239900000004)